Serological Diagnosis Of Viral Hepatitis. amna alotiby
1.1 - What is viral Hepatitis? <ul><li>Viral Hepatitis is a systemic disease, which primarily affects the liver. Viral hep...
HBV Markers  amna alotiby
2.2.3 - Serological test patterns HBV :   amna alotiby Interpretation  Test  Anti-HBc 1gM HBc total HBe Ab HBe  Ag HBs  Ab...
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Serological diagnosis of viral hepatitis

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Serological diagnosis of viral hepatitis

  1. 1. Serological Diagnosis Of Viral Hepatitis. amna alotiby
  2. 2. 1.1 - What is viral Hepatitis? <ul><li>Viral Hepatitis is a systemic disease, which primarily affects the liver. Viral hepatitis is caused by one of the following pathogens: </li></ul><ul><li>Hepatitis A virus (HAV) . </li></ul><ul><li>Hepatitis B virus (HBV) . </li></ul><ul><li>Hepatitis C virus (HCV). </li></ul><ul><li>Hepatitis D virus (HDV). </li></ul><ul><li>Hepatitis E virus (HEV). </li></ul><ul><li>Hepatitis G virus (HGV) </li></ul><ul><li>Clinically , it is difficult to make a reliable clinical distinction among cases caused by the hepatitis viruses, so, only serologic tests can distinguish these different types of viral hepatitis. </li></ul>amna alotiby
  3. 3. HBV Markers amna alotiby
  4. 4. 2.2.3 - Serological test patterns HBV : amna alotiby Interpretation Test Anti-HBc 1gM HBc total HBe Ab HBe Ag HBs Ab HBs Ag .Early acute HBV or Late incubation. - - - - - + Early acute HBV, Highly infectious - - - + - + Acute HBV + + - + - + Convalescence + + + - - - Early recovery + + + - + - Recovery - + + - + - Chronic infection (Chronic carrier) - + ± ± - + History of HBV infection Without immunity - + - - - - History of HBV infection With immunity - + - - + - HBV vaccination or Passive transfer antibodies - - - - + -
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