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Serological diagnosis of viral hepatitis

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  • 1. Serological Diagnosis Of Viral Hepatitis. amna alotiby
  • 2. 1.1 - What is viral Hepatitis?
    • Viral Hepatitis is a systemic disease, which primarily affects the liver. Viral hepatitis is caused by one of the following pathogens:
    • Hepatitis A virus (HAV) .
    • Hepatitis B virus (HBV) .
    • Hepatitis C virus (HCV).
    • Hepatitis D virus (HDV).
    • Hepatitis E virus (HEV).
    • Hepatitis G virus (HGV)
    • Clinically , it is difficult to make a reliable clinical distinction among cases caused by the hepatitis viruses, so, only serologic tests can distinguish these different types of viral hepatitis.
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  • 3. HBV Markers amna alotiby
  • 4. 2.2.3 - Serological test patterns HBV : amna alotiby Interpretation Test Anti-HBc 1gM HBc total HBe Ab HBe Ag HBs Ab HBs Ag .Early acute HBV or Late incubation. - - - - - + Early acute HBV, Highly infectious - - - + - + Acute HBV + + - + - + Convalescence + + + - - - Early recovery + + + - + - Recovery - + + - + - Chronic infection (Chronic carrier) - + ± ± - + History of HBV infection Without immunity - + - - - - History of HBV infection With immunity - + - - + - HBV vaccination or Passive transfer antibodies - - - - + -

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