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LYMPHOID TISSUE
1. Primary – Thymus
- Bone marrow
2. Secondary - lymph nodes,
lymphoid follicles in tonsils,
Peyer's patches,
spleen,
adenoids,
skin, etc.
3. Tertiary - Distributed groups
of lymphocytes
Generate lymphocytes from
Immature progenitor cells
Secondary or peripheral lymphoid organs maintain mature
naive lymphocytes and initiate an adaptive immune response
Theses are the sites of lymphocyte activation by antigen
Activation leads to clonal expansion and affinity maturation
Mature Lymphocytes recirculate between the blood and the
peripheral lymphoid organs until they encounter their
specific antigen
GALT Gut associated lymphoid tissue
MALT mucosa-associated lymphatic tissue; lymphoid tissue associated
with the mucosa of the female reproductive tract, respiratory tract, etc
SALT Skin associated - dermis of the skin
Precursor cells in the bone marrow produce lymphocytes.
B-lymphocytes (B-cells) mature in the bone marrow.
T-lymphocytes (T-cells) mature in the thymus gland.
The ducts of the lymphatic system provide transportation
for proteins, fats, and other substances in a medium called lymph.
Lymph "Means clear water and it is basically the fluid and protein
that has been squeezed out of the blood (i.e. blood plasma).
"Unlike the cardiovascular system,
the lymphatic system is not closed and has no central pump."
"Lymph movement occurs despite low pressure due to peristalsis –
smooth muscle and skeletal activity
(everyday activity and motion of the body).
Nasopharynx
Oropharynx
Laryngopharynx
Oesophagus
Cricoid
Fold by Levator palatini
Salpingopharyngeal fold
Tensor veli palatini Levator veli palatini
The palatine tonsil is an ovoid mass of lymphoid tissue
located in the oropharynx between the
anterior and posterior pillars
It has a 2 surfaces – medial and lateral and
2 poles – upper and lower
Medial surface
It is lined by stratified squamous non keratinising epithelium which dips into
the crypts
The crypts are 12-15 in number
Secondary crypts arise from the primary crypts and extend into the
substance of the tonsil
On of the crypts located in the upper part are larger than
the rest – crypta magna
It represents the ventral part of second pharyngeal pouch
The crypts serve to increase the surface area of the tonsil
The crypts may be filled witth cheesy material
– epithelial debris, food particles and bacteria
Lateral surface
It is covered by the fibrous capsule of the tonsil
The tonsillar bed is separated from the capsule by loose areolar tissue
This makes it is easy to dissect the tonsil from its bed during tonsillectomy
It is the site of collection of pus in peritonsillar abscess (quinsy)
Some fibers of palatoglossus and palatopharyngeus gets attached
to capsule of tonsil
Bed of tonsil
It is formed by the 2 muscles
Superior constrictor
Styloglossus
Tensor veli palitini Lavator veli palitini
Palatopharyngeus
Structures related to bed of tonsil
The tonsil is separated from its bed by loose areolar tissue.
The structures forming the bed of the tonsil are:
Superior constrictor muscle
Styloglossus muscle
The structures related to the bed of the tonsil are:
styloid process (if enlarged)
glossopharyngeal nerve
facial artery
submandibular salivary gland
posterior belly of digastric
medial pterygoid muscle
angle of mandible
PS: Palatine / External palatine / Paratonsillar vein
Upper pole
It extends into the soft palate
There is a semilunar fold of mucous membrane which covers the
medial part of the upper pole
It extends from anterior pillar to posterior pillar
It encloses a potential space – supratonsillar fossa
Lower pole
It is attached to the tongue
A triangular fold of mucous membrane extends from the
anterior tonsillar pillar to the lower pole
It encloses a space – anterior tonsillar space
The lower pole is separated from the tongue by the tonsillo-lingual sulcus
This sulcus may harbour carcinoma
Blood supply
The tonsil is supplied by branches of external carotid artery
The tonsil is supplied by 5 arteries:
Tonsillar branch of facial artery (main supply)
Ascending palatine branch of facial artery
Ascending pharyngeal branch of external carotid artery
Dorsal linguae branch of lingual artery
Descending palatine branch of maxillary artery
Blood supply from medial surface
Venous drainage
Blood from the tonsil drains into the paratonsillar vein which in turn
drains into the common facial vein and pharyngeal venous plexus
Lymphatic drainage
Lymphatics from the tonsil pierce the superior constrictor and drain
into the upper cervical lymph nodes especially jugulodigastric (tonsillar)
lymph node
Enlarged non tender jugulodigastric lymph node is a sign of
chronic tonsillitis
Facial vein
Omohyoid muscle Supraclavicular nodes
Digastric muscle
Internal Jugular vein
Jugulo-omohyoid node
JUGULO-DIGASTRIC NODE
Nerve supply
Lesser palatine branch of sphenopalatine ganglion
Glossopharyngeal nerve
Nerve supply
Lesser palatine branch of sphenopalatine ganglion
Glossopharyngeal nerve
Waldeyer’s lymaphatic ring
Functions of tonsil
It has a protective function in that it prevents entry of pathogens
through the nasal and oral route
The crypts on the surface of the tonsil serve to increase the
surface area and increase the efficiency of protection against pathogens
It forms a part of Waldeyer’s lymphatic ring
Applied anatomy
Tonsils prevent infection.
Infected tonsils act as septic focus
Damage of paratonsillar vein during tonsillectomy leads to
excessive venous haemorhhage
Damage to glossopharygeal nerve leads to loss of taste sensation
Infected tonsillar pain may be referred to middle ear because of
Same nerve supply

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Palatine tonsil

  • 1.
  • 2. LYMPHOID TISSUE 1. Primary – Thymus - Bone marrow 2. Secondary - lymph nodes, lymphoid follicles in tonsils, Peyer's patches, spleen, adenoids, skin, etc. 3. Tertiary - Distributed groups of lymphocytes Generate lymphocytes from Immature progenitor cells
  • 3. Secondary or peripheral lymphoid organs maintain mature naive lymphocytes and initiate an adaptive immune response Theses are the sites of lymphocyte activation by antigen Activation leads to clonal expansion and affinity maturation Mature Lymphocytes recirculate between the blood and the peripheral lymphoid organs until they encounter their specific antigen GALT Gut associated lymphoid tissue MALT mucosa-associated lymphatic tissue; lymphoid tissue associated with the mucosa of the female reproductive tract, respiratory tract, etc SALT Skin associated - dermis of the skin
  • 4. Precursor cells in the bone marrow produce lymphocytes. B-lymphocytes (B-cells) mature in the bone marrow. T-lymphocytes (T-cells) mature in the thymus gland. The ducts of the lymphatic system provide transportation for proteins, fats, and other substances in a medium called lymph. Lymph "Means clear water and it is basically the fluid and protein that has been squeezed out of the blood (i.e. blood plasma). "Unlike the cardiovascular system, the lymphatic system is not closed and has no central pump." "Lymph movement occurs despite low pressure due to peristalsis – smooth muscle and skeletal activity (everyday activity and motion of the body).
  • 6. Tensor veli palatini Levator veli palatini
  • 7.
  • 8. The palatine tonsil is an ovoid mass of lymphoid tissue located in the oropharynx between the anterior and posterior pillars It has a 2 surfaces – medial and lateral and 2 poles – upper and lower
  • 9. Medial surface It is lined by stratified squamous non keratinising epithelium which dips into the crypts The crypts are 12-15 in number Secondary crypts arise from the primary crypts and extend into the substance of the tonsil On of the crypts located in the upper part are larger than the rest – crypta magna It represents the ventral part of second pharyngeal pouch The crypts serve to increase the surface area of the tonsil The crypts may be filled witth cheesy material – epithelial debris, food particles and bacteria
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  • 11. Lateral surface It is covered by the fibrous capsule of the tonsil The tonsillar bed is separated from the capsule by loose areolar tissue This makes it is easy to dissect the tonsil from its bed during tonsillectomy It is the site of collection of pus in peritonsillar abscess (quinsy) Some fibers of palatoglossus and palatopharyngeus gets attached to capsule of tonsil
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  • 15. Bed of tonsil It is formed by the 2 muscles Superior constrictor Styloglossus
  • 16. Tensor veli palitini Lavator veli palitini
  • 18. Structures related to bed of tonsil The tonsil is separated from its bed by loose areolar tissue. The structures forming the bed of the tonsil are: Superior constrictor muscle Styloglossus muscle The structures related to the bed of the tonsil are: styloid process (if enlarged) glossopharyngeal nerve facial artery submandibular salivary gland posterior belly of digastric medial pterygoid muscle angle of mandible
  • 19.
  • 20. PS: Palatine / External palatine / Paratonsillar vein
  • 21. Upper pole It extends into the soft palate There is a semilunar fold of mucous membrane which covers the medial part of the upper pole It extends from anterior pillar to posterior pillar It encloses a potential space – supratonsillar fossa
  • 22. Lower pole It is attached to the tongue A triangular fold of mucous membrane extends from the anterior tonsillar pillar to the lower pole It encloses a space – anterior tonsillar space The lower pole is separated from the tongue by the tonsillo-lingual sulcus This sulcus may harbour carcinoma
  • 23. Blood supply The tonsil is supplied by branches of external carotid artery The tonsil is supplied by 5 arteries: Tonsillar branch of facial artery (main supply) Ascending palatine branch of facial artery Ascending pharyngeal branch of external carotid artery Dorsal linguae branch of lingual artery Descending palatine branch of maxillary artery
  • 24. Blood supply from medial surface
  • 25.
  • 26. Venous drainage Blood from the tonsil drains into the paratonsillar vein which in turn drains into the common facial vein and pharyngeal venous plexus
  • 27. Lymphatic drainage Lymphatics from the tonsil pierce the superior constrictor and drain into the upper cervical lymph nodes especially jugulodigastric (tonsillar) lymph node Enlarged non tender jugulodigastric lymph node is a sign of chronic tonsillitis
  • 28. Facial vein Omohyoid muscle Supraclavicular nodes Digastric muscle Internal Jugular vein Jugulo-omohyoid node JUGULO-DIGASTRIC NODE
  • 29. Nerve supply Lesser palatine branch of sphenopalatine ganglion Glossopharyngeal nerve
  • 30. Nerve supply Lesser palatine branch of sphenopalatine ganglion Glossopharyngeal nerve
  • 32. Functions of tonsil It has a protective function in that it prevents entry of pathogens through the nasal and oral route The crypts on the surface of the tonsil serve to increase the surface area and increase the efficiency of protection against pathogens It forms a part of Waldeyer’s lymphatic ring Applied anatomy Tonsils prevent infection. Infected tonsils act as septic focus Damage of paratonsillar vein during tonsillectomy leads to excessive venous haemorhhage Damage to glossopharygeal nerve leads to loss of taste sensation Infected tonsillar pain may be referred to middle ear because of Same nerve supply