After a symptom-free incubation period that ranges from 10 days to a year or longer (the average is 30 to 50 days), the patient complains of malaise, loss of appetite, fatigue , headache , and fever . Over half of all patients have pain (sometimes itching) or numbness at the site of exposure. They may complain of insomnia or depression .
Two to 10 days later, signs of nervous system damage appear, hyperactivity and hypersensitivity, disorientation , hallucinations, seizures, and paralysis . Death may be sudden, due to cardiac or respiratory arrest, or follow a period of coma that can last for months with the aid of life-support measures .
What diseases could be treated with gene therapy? ( From AMA website.)
About 4,000 diseases have been traced to gene disorders. Current and possible candidates for gene therapy include cancer , AIDS , cystic fibrosis , Parkinson’s and Alzheimer’s diseases , amyotrophic lateral sclerosis ( Lou Gehrig's disease ), cardiovascular disease and arthritis .