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Topicals, Opthalmics and Otics Structure of the Skin Disease Conditions Therapeutic Agents
Structure and Function of the Skin
 
<ul><li>Ultraviolet Radiation </li></ul><ul><ul><li>Skin cancer </li></ul></ul><ul><ul><li>Wrinkles </li></ul></ul><ul><li...
Common Disease of the Skin
Contact Dermatitis by Poison Ivy
 
<ul><li>Classic Poison Ivy  Poison Ivy Eye </li></ul><ul><li>Rash developed puss  edema </li></ul>
Antiseptics and Disinfectants <ul><li>A substance that inhibits the growth & developmt of moos, but does not necessarily k...
Topical Antibiotics <ul><li>Silvadene, SSD cream (silver sulfadiazine) </li></ul><ul><li>Triple antibiotics (bacitracin-ne...
Topical Corticosteroids <ul><li>OTC versus RX </li></ul><ul><li>Creams, ointments, gels, lotions </li></ul><ul><li>Agents ...
Psoriasis
Psoriasis <ul><li>Immune mediated skin disease which causes rapid growth of skin cells.  </li></ul><ul><li>Treatments </li...
www.Psoriasis.org courtesy of Jennifer Marks PTech student 2005
Fungal Infections <ul><li>DANDRUFF </li></ul><ul><li>Shedding of scales from the scalp </li></ul><ul><li>Selsun Blue </li>...
Candidiasis Infections <ul><li>Ringworm </li></ul><ul><li>Topicals </li></ul><ul><ul><li>Clotrimazole </li></ul></ul><ul><...
Diaper Rash
Acute PCN uticaria Drug Induced Maculopapular eruption Drug Induced erythema multiforme
Toxic-Drug Epidermal Necrolysis Fixed eruption by Pb Iodide acneiform eruption
Atopic Dermatitis Eruption <ul><li>Treatments </li></ul><ul><ul><li>Topical/PO Cortisone </li></ul></ul><ul><ul><li>Topica...
Infantile Phase 6 weeks to 4 yo
Eczema
ECZEMA <ul><li>Atopic </li></ul><ul><ul><li>Doxepin (Zonalon) </li></ul></ul><ul><li>Contact </li></ul><ul><ul><li>Pimecro...
Lesion of Psoriasis Keloid Scarring from acne
<ul><li>Scaly skin lesion caused by too much sun can lead to skin cancer </li></ul><ul><li>Actinex (masoprocol) </li></ul>...
<ul><li>Triggers: </li></ul><ul><li>Sun, Stress, Hot Weather/Bath </li></ul><ul><li>Wind, Exercise, Etoh,  </li></ul><ul><...
Acne Vulgaris and Wrinkles <ul><li>Overactive sebaceous glands </li></ul><ul><li>Azithromycin (qd) </li></ul><ul><li>Treti...
Scar Management <ul><li>Pressure/Compression </li></ul><ul><ul><li>Stimulates production of collagenase, reduces height of...
Viral Infection <ul><li>Shingles, cold sores </li></ul><ul><ul><li>OTC Docosanol (Abreva) </li></ul></ul><ul><ul><li>Rx or...
Moles
LICE and their Nits
Pubic Louse Body Louse
Pediculicides and Scabicides <ul><li>Human Lice & scabies are external parasites </li></ul><ul><li>Transmission by direct ...
Louse Life Cycle
Scabies <ul><li>What are they? </li></ul><ul><li>Sites of Scabies Infestation </li></ul><ul><li>Symptoms </li></ul><ul><li...
 
Hair Loss <ul><li>Rogaine (Minoxidil) </li></ul><ul><li>MOA </li></ul><ul><li>SE </li></ul><ul><li>Efficacy </li></ul>
Diseases of the Eye <ul><li>Glaucoma </li></ul><ul><li>Cataract </li></ul><ul><li>Vascular </li></ul><ul><li>Retinophathie...
<ul><li>A Look </li></ul><ul><li>Inside </li></ul><ul><li>The EYE </li></ul>
<ul><li>Why Does </li></ul><ul><li>Glaucoma </li></ul><ul><li>Happen? </li></ul>
Risk Factors <ul><li>Age </li></ul><ul><li>Diabetes </li></ul><ul><li>Family History </li></ul><ul><li>Eye Injury </li></u...
 
Agents for Glaucoma <ul><li>Goal of Treatment </li></ul><ul><li>Therapeutic Agents </li></ul><ul><ul><li>Alpha-agonist  –r...
Infections of the Eye <ul><li>Conjunctivitis-pink eye </li></ul><ul><ul><li>Inflammation of the lining & inner surface of ...
Anatomy of the EAR
<ul><li>Hearing Loss </li></ul><ul><ul><li>Age related </li></ul></ul><ul><ul><li>65-75 years of age </li></ul></ul><ul><u...
Commonly Used Otic Agents <ul><li>Analgesics </li></ul><ul><ul><li>Antipyrine-benzocaine (Auralgan) </li></ul></ul><ul><li...
Summary Slide <ul><li>Common Disease of the Skin </li></ul><ul><li>Antiseptics and Disinfectants </li></ul><ul><li>Topical...
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Topicals, opthal, otics

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Transcript of "Topicals, opthal, otics"

  1. 4. Topicals, Opthalmics and Otics Structure of the Skin Disease Conditions Therapeutic Agents
  2. 5. Structure and Function of the Skin
  3. 7. <ul><li>Ultraviolet Radiation </li></ul><ul><ul><li>Skin cancer </li></ul></ul><ul><ul><li>Wrinkles </li></ul></ul><ul><li>Phototoxicity </li></ul><ul><ul><li>Excessive response </li></ul></ul><ul><ul><li>in the presence of a </li></ul></ul><ul><ul><li>sensitizing agent </li></ul></ul><ul><ul><ul><li>Sunblocks </li></ul></ul></ul><ul><ul><ul><li>Sunscreens </li></ul></ul></ul><ul><li>Photosensitivity </li></ul><ul><ul><li>Abnormal response </li></ul></ul>
  4. 8. Common Disease of the Skin
  5. 9. Contact Dermatitis by Poison Ivy
  6. 11. <ul><li>Classic Poison Ivy Poison Ivy Eye </li></ul><ul><li>Rash developed puss edema </li></ul>
  7. 12. Antiseptics and Disinfectants <ul><li>A substance that inhibits the growth & developmt of moos, but does not necessarily kill them </li></ul><ul><li>Hibiclens (chlorhexidine) </li></ul><ul><li>Phisohex (hexachlorophene) </li></ul><ul><li>Betadine (povidine- iodine) </li></ul><ul><li>A chemical applied to objects to free them from pathogenic organisms </li></ul><ul><li>Alcohol </li></ul><ul><li>Chlorox </li></ul><ul><li>Hydrogen peroxide </li></ul>
  8. 13. Topical Antibiotics <ul><li>Silvadene, SSD cream (silver sulfadiazine) </li></ul><ul><li>Triple antibiotics (bacitracin-neomycin-polymixin B) </li></ul><ul><li>Cleocin T (clindamycin) </li></ul><ul><li>Bactroban (mupirocin) </li></ul>
  9. 14. Topical Corticosteroids <ul><li>OTC versus RX </li></ul><ul><li>Creams, ointments, gels, lotions </li></ul><ul><li>Agents </li></ul><ul><ul><li>Betamethasone (Diprolene, Diprosone) </li></ul></ul><ul><ul><li>Clobetasol (Temovate) </li></ul></ul><ul><ul><li>Fluocinonide (Lidex) </li></ul></ul>
  10. 15. Psoriasis
  11. 16. Psoriasis <ul><li>Immune mediated skin disease which causes rapid growth of skin cells. </li></ul><ul><li>Treatments </li></ul><ul><ul><li>Corticosteroids (Reduce inflammation & slow skin cell turnover </li></ul></ul><ul><ul><li>Salicylic acid -Peeler </li></ul></ul><ul><ul><li>Ultraviolet Phototherapy </li></ul></ul><ul><ul><ul><li>Reduce skin cell turnover </li></ul></ul></ul><ul><ul><li>Systemic Immune System Therapy- MTX </li></ul></ul>
  12. 17. www.Psoriasis.org courtesy of Jennifer Marks PTech student 2005
  13. 18. Fungal Infections <ul><li>DANDRUFF </li></ul><ul><li>Shedding of scales from the scalp </li></ul><ul><li>Selsun Blue </li></ul><ul><ul><li>Selenium sulfide </li></ul></ul><ul><li>Head & Shoulders </li></ul><ul><ul><li>Pyrithione zinc </li></ul></ul><ul><li>Nizoral </li></ul>
  14. 19. Candidiasis Infections <ul><li>Ringworm </li></ul><ul><li>Topicals </li></ul><ul><ul><li>Clotrimazole </li></ul></ul><ul><ul><li>Miconazole </li></ul></ul><ul><li>Oral </li></ul><ul><ul><li>Griseofulvin </li></ul></ul><ul><ul><li>Itraconzaole (Sporanox) </li></ul></ul><ul><ul><ul><li>Pulse Dose </li></ul></ul></ul><ul><li>Terbinafine (Lamisil) </li></ul>
  15. 20. Diaper Rash
  16. 21. Acute PCN uticaria Drug Induced Maculopapular eruption Drug Induced erythema multiforme
  17. 22. Toxic-Drug Epidermal Necrolysis Fixed eruption by Pb Iodide acneiform eruption
  18. 23. Atopic Dermatitis Eruption <ul><li>Treatments </li></ul><ul><ul><li>Topical/PO Cortisone </li></ul></ul><ul><ul><li>Topical (Doxepin) </li></ul></ul><ul><ul><li>Topical Calcineurin </li></ul></ul><ul><ul><li>Immunosuppressants </li></ul></ul><ul><ul><li>Emollients/Antihistam </li></ul></ul><ul><ul><li>Coal Tar </li></ul></ul>Allergic Hereditary Psychogenic
  19. 24. Infantile Phase 6 weeks to 4 yo
  20. 25. Eczema
  21. 26. ECZEMA <ul><li>Atopic </li></ul><ul><ul><li>Doxepin (Zonalon) </li></ul></ul><ul><li>Contact </li></ul><ul><ul><li>Pimecrolimus (Elidel) </li></ul></ul><ul><ul><li>Tacrolimus (Protopic) </li></ul></ul>
  22. 27. Lesion of Psoriasis Keloid Scarring from acne
  23. 28. <ul><li>Scaly skin lesion caused by too much sun can lead to skin cancer </li></ul><ul><li>Actinex (masoprocol) </li></ul><ul><li>Efudex (fluorouracil) </li></ul>Actinic Keratosis
  24. 29. <ul><li>Triggers: </li></ul><ul><li>Sun, Stress, Hot Weather/Bath </li></ul><ul><li>Wind, Exercise, Etoh, </li></ul><ul><li>Metrogel/crm (metronidazole) </li></ul>Rosacea
  25. 30. Acne Vulgaris and Wrinkles <ul><li>Overactive sebaceous glands </li></ul><ul><li>Azithromycin (qd) </li></ul><ul><li>Tretinoin </li></ul><ul><li>Benzoyl peroxide </li></ul><ul><li>Tazarotene (Tazorac) </li></ul><ul><li>Ortho Tri-Cyclen </li></ul><ul><li>Differin/Azelex </li></ul><ul><li>Retin A </li></ul><ul><ul><li>Tretinoin, retinoic acid, vitamin A acid </li></ul></ul><ul><li>Renova </li></ul><ul><ul><li>Lower dose for fine wrinkles </li></ul></ul><ul><ul><li>Moisturizing base </li></ul></ul><ul><li>Kinerase </li></ul><ul><li>Tazorac </li></ul><ul><li>Botox </li></ul>
  26. 31. Scar Management <ul><li>Pressure/Compression </li></ul><ul><ul><li>Stimulates production of collagenase, reduces height of scar thru local tissue hypoxia </li></ul></ul><ul><li>Occlusive/Silicone Sheeting </li></ul><ul><ul><li>Provides hydration </li></ul></ul><ul><li>Cortisone </li></ul><ul><ul><li>Reduces pain and itching </li></ul></ul><ul><li>Vitamin E </li></ul><ul><ul><li>Moisturizes </li></ul></ul>
  27. 32. Viral Infection <ul><li>Shingles, cold sores </li></ul><ul><ul><li>OTC Docosanol (Abreva) </li></ul></ul><ul><ul><li>Rx oral anti-virals </li></ul></ul><ul><li>Warts </li></ul><ul><ul><li>OTC Cryotherapy </li></ul></ul><ul><ul><li>Rx Aldara </li></ul></ul>
  28. 33. Moles
  29. 34. LICE and their Nits
  30. 35. Pubic Louse Body Louse
  31. 36. Pediculicides and Scabicides <ul><li>Human Lice & scabies are external parasites </li></ul><ul><li>Transmission by direct contact </li></ul><ul><li>Types </li></ul><ul><ul><li>Body lice </li></ul></ul><ul><ul><li>Head lice </li></ul></ul><ul><ul><li>Pubic lice (Crabs) </li></ul></ul><ul><li>Treatments </li></ul><ul><ul><li>Permethrin (Nix/Elimite) </li></ul></ul>
  32. 37. Louse Life Cycle
  33. 38. Scabies <ul><li>What are they? </li></ul><ul><li>Sites of Scabies Infestation </li></ul><ul><li>Symptoms </li></ul><ul><li>Etiology </li></ul><ul><li>Treatments </li></ul>
  34. 40. Hair Loss <ul><li>Rogaine (Minoxidil) </li></ul><ul><li>MOA </li></ul><ul><li>SE </li></ul><ul><li>Efficacy </li></ul>
  35. 41. Diseases of the Eye <ul><li>Glaucoma </li></ul><ul><li>Cataract </li></ul><ul><li>Vascular </li></ul><ul><li>Retinophathies </li></ul><ul><li>Retinopathy </li></ul>
  36. 42. <ul><li>A Look </li></ul><ul><li>Inside </li></ul><ul><li>The EYE </li></ul>
  37. 43. <ul><li>Why Does </li></ul><ul><li>Glaucoma </li></ul><ul><li>Happen? </li></ul>
  38. 44. Risk Factors <ul><li>Age </li></ul><ul><li>Diabetes </li></ul><ul><li>Family History </li></ul><ul><li>Eye Injury </li></ul><ul><li>Far & Nearsightedness </li></ul><ul><li>Drugs (cortisone) </li></ul>
  39. 46. Agents for Glaucoma <ul><li>Goal of Treatment </li></ul><ul><li>Therapeutic Agents </li></ul><ul><ul><li>Alpha-agonist –reduce production & increase drainage </li></ul></ul><ul><ul><ul><li>Brimonidine (Alphagan) </li></ul></ul></ul><ul><ul><li>Beta-blockers –reduce aqueous fluid </li></ul></ul><ul><ul><ul><li>Betaxolol (Betoptic) </li></ul></ul></ul><ul><ul><li>Carbonic Anhydrase Inhibitors –reduce production </li></ul></ul><ul><ul><ul><li>Dorzolamide (Trusopt) </li></ul></ul></ul><ul><ul><li>Prostaglandin Analogs –increase drainage </li></ul></ul><ul><ul><ul><li>Latanoprost (Xalatan) </li></ul></ul></ul>
  40. 47. Infections of the Eye <ul><li>Conjunctivitis-pink eye </li></ul><ul><ul><li>Inflammation of the lining & inner surface of eyelid </li></ul></ul><ul><ul><li>Allergic,Bacterial,Viral </li></ul></ul><ul><li>Stye </li></ul><ul><ul><li>Infection of sebaceous gland (hordeolum) in lid margin </li></ul></ul><ul><li>Blepharitis </li></ul><ul><ul><li>Eyelid margins, scales crusts, ulcers </li></ul></ul><ul><li>Antibiotics </li></ul><ul><ul><li>Tobramycin,gentamycin, sulfacetamide </li></ul></ul><ul><li>Antihistamines </li></ul><ul><ul><li>Zaditor, Alamast </li></ul></ul><ul><li>Corticosteroids </li></ul><ul><ul><li>Dexamethasone, Flurometholone </li></ul></ul><ul><li>Antivirals </li></ul><ul><ul><li>Vira-A (vidarabine) </li></ul></ul>
  41. 48. Anatomy of the EAR
  42. 49. <ul><li>Hearing Loss </li></ul><ul><ul><li>Age related </li></ul></ul><ul><ul><li>65-75 years of age </li></ul></ul><ul><ul><li>Environmental </li></ul></ul><ul><ul><li>Genetic </li></ul></ul>
  43. 50. Commonly Used Otic Agents <ul><li>Analgesics </li></ul><ul><ul><li>Antipyrine-benzocaine (Auralgan) </li></ul></ul><ul><li>Antibiotics </li></ul><ul><ul><li>Cortisporin HC Solution or Suspension </li></ul></ul><ul><ul><li>CiproDex </li></ul></ul><ul><li>Wax dissolvers </li></ul><ul><ul><li>Cerumenex (Rx) </li></ul></ul><ul><ul><li>Debrox (OTC) </li></ul></ul>
  44. 51. Summary Slide <ul><li>Common Disease of the Skin </li></ul><ul><li>Antiseptics and Disinfectants </li></ul><ul><li>Topical Antibiotics, Topical Corticosteroids </li></ul><ul><li>Hair Loss </li></ul><ul><li>Diseases of the Eye </li></ul><ul><li>Agents for Glaucoma </li></ul><ul><li>Conjunctivitis “Pink Eye” </li></ul><ul><li>Commonly Used Otic Agents </li></ul>
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