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With microfractures comes callus formation and hence more stiffness and more microfracture.
Third event: metaplasia of the peripheral synovial cells resulting in formation of osteochondrophytes ( combination bone, connective tissue, fibrocartilage and island of hyaline cartilage on the surface.
OA of the cervical and lumbar spine: is common. In the cervical spine the symptoms may be related to radiculitis by compression of nerve roots secondary to proliferative osteochondrophytes, functional compromise of the vertebral artery, neuromyopathy secondary to compresion, spinal cord infarcts or esophageal compression, by anterior bony projection.