Latest Hair Loss Research & Technique Breakthrough  In 2012
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Latest Hair Loss Research & Technique Breakthrough In 2012



Hair loss is a very rampant problem in men today. In fact statistics show that balding may already start around the age of 35 and with 85% of hair loss victims going totally bald or experiencing ...

Hair loss is a very rampant problem in men today. In fact statistics show that balding may already start around the age of 35 and with 85% of hair loss victims going totally bald or experiencing severe hair thinning at the age of 50.

FUE & FUE hair transplant from Esteem Cosmetic Studio in Sydney, Brisbane and Canberra. Call 1300 378 336 or visit

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Latest Hair Loss Research & Technique Breakthrough  In 2012 Latest Hair Loss Research & Technique Breakthrough In 2012 Document Transcript

  • LatestHair LossRESEARCH &TECHNIQUEBreakthroughin 2012
  • New Drugthat inhibitPGD2Hair loss in men seems to be too common that we no longermake double takes when someone sports a shiny and totallybarren scalp. But this doesn’t always hold true for those whosuffer from it. No matter how common this is for men, theimpact that this condition have on the self-esteem is a differentstory in itself. And that is why a lot are hopeful whensomething new is discovered which promises to treat hair loss.Fortunately reports surfaced claiming that a new treatment forhair loss would be available in stores soon. This was to targetanother chemical in the body that is also discovered to triggerexcessive hair loss.Just this year when dermatologists from the US claimed thatthey found an enzyme that is also responsible for hair loss. Inthe past, the commonly known reason for excessive hairshedding is 5-alpha reductase. This is an enzyme that ispresent in minute amounts in the muscle that when it comes incontact with the male hormone testosterone, it converts it toDHT or dihyrotestosterone, which causes hair loss.There are 5-alpha reductase inhibitors that are out in themarket to combat the effects of DHT to the hair. Otherindications for it include benign prostatic hyperplasia andlower urinary tract infections. However, with the discoverythat hair loss may also be triggered by another enzyme, it goeswithout saying that the common cure may not be applicablefor some cases.
  • There are 5-alpha reductase inhibitorsthat are out in the market to combat theeffects of DHTThe other villain that causes hair loss is called prostaglandingD2 or PGD2. This resulted after they screened 250 genes thatwere suspected to cause hair loss. Its destructive effects startwhen it signals the hair follicles to stop reproducing. This, ofcourse, ultimately leads to balding.However, the drugs that inhibit PGD2 are actually alreadyavailable, but the treatment of hair loss is still an off label use.And because of that George Cotsarelis, who is the head of thedermatology department in Pennsylvania University, havebeen talking to drug firms about an anti-baldness product thattargets this particular enzyme.In a research done by Cotsarelis and his team, they found outthat the hair loss that the presence of PGD2 in the scalp wasthree times higher in balding areas compared to those that stillhas hair.The studies showed that the process of hair loss starts out withthe hairs starting to thin when exposed to these specificenzyme. Then it eventually causes it to shrink and shed off.The bald areas may still produce hair; however it may berather flimsy at first. But over time it tends shrink smaller andsmaller until the hair follicle no longer produce any hair,resulting in permanent baldness.When the study was published in Science of TranslationalMedicine back in March, Cotsarelis mentioned that if theinhibition that is caused by the presence of PGD2 is removedor treated, there is a very good chance that hair would developyet again. That is why, it is not only a hope for treating hairthinning but balding as well.For those who may not be a good candidate for hair transplantand are losing their hair permanently, this could be a goodchance to restore a full head of hair.
  • Stem CellTherapy forHair LossThe approach of stem cell hair loss therapy is basically thesame as the other techniques preceding it. It does not use anyartificial materials, but rather the patient’s own blood topromote hair growth.Stem cell is found in various organs in the body and it is foundto adapt and transform itself to the tissue or organ assuming animportant role in repairing and maintaining healthy tissues.Experts thought that this also carries on to a balding scalp.This has proven to be an effective hair loss treatment whenused on mice, that is why phase II studies are underway, whichis to prove if this can also provide better hair regrowth onhumans (both males and females).The treatment would involve the process of drawing bloodfrom the patient which is then centrifuged to separate theplasma component which contains growth factors and stemcells. Once this has been collected, the surgeon injects this intothe affected area. In order to improve the migration of the stemcells to area of focus, a laser light is directed over it. The entireprocedure is reported to create some amount of discomfort butit can be finished in just an hour, and it would only have to beperformed once.Stem cell hair loss therapy is approved by the FDA as aninjectable treatment to promote wound healing in hairtransplants but not on regrowing hair. Studies are stillunderway with researchers saying that results could bepublished later this year. Meanwhile, while this promising hairloss treatment is still in the works, you can still opt for otherhair restoration measures available.
  • 2.1 Platelet Rich Plasma (PRP)PRP treatment is done by first collecting around 60-100 ml ofblood from your vein, which would have to be done by aphlebotomist or a nurse. This will placed on a special containerand then spun on a centrifuge to separate the different bloodcomponents. The time in the centrifuge would takeapproximately 15 minutes and after that your plasma will beseparated from the other blood materials.The plasma component which is teeming with stem cells andgrowth factors is then collected and prepared for injection tothe scalp. A micro needle roller device is used foradministration, but despite the size, the scalp would have to beprepared with topical anesthesia to make the procedure lesspainful.The roller device would create micro trauma to the scalpstimulating the healing process. While this is happening, PRPis also injected into the area simultaneously. The area wouldhave to be wrapped with occlusive dressing later on to preventbleeding, lessening the effectiveness of the treatment.During the healing process the platelet rich plasma willgenerate thicker and healthier hair growth as the stem cells ofthe transplanted hair follicles are stimulated. It is alsoadvisable that patients prevent taking anti-inflammatorymedications because this might impair the healing process.And they must remember to stay out of the sun and protect thearea at all times.The first few days after the procedure might cause someswelling on your scalp. In rare occasions an infection mayeven be possible. But with the right techniques used by anexperienced and reputable surgeon, this can be avoided.Allergic reactions wouldn’t be an issue in this kind oftreatment, because you are basically using your own blood.Generally, the outcome of this procedure is often highlysatisfactory with an 80% success rate. Scientific studies haveproven that Platelet Rich Plasma promotes best results for hairtransplant procedure as shown by successful results over theyears.
  • GlaucomaEye DropsWho would have thought that a possible cure for hair loss couldsimply be right before the eyes of many glaucoma patients?Studies found that the drug Lumigan which is indicated forglaucoma, an eye condition that leads to optic nerve damage dueto increased intra-ocular pressure (IOP), helps relieve hair loss.It was already observed that continued use of the drug stimulatesthe growth of the eyelashes. This was due to the active ingredientof the drug which is Bimatoprost. Research suggested that thiscould also have the same effect on scalp hair.Professor Valerie Randall, who is also the lead scientist in theresearch done at University of Bradford in Bradford, UK, said ina statement that they hoped “this study will lead to thedevelopment of a new therapy for balding which should improvethe quality of life for many people with hair loss.”There tests were able to find a molecular signaling pathway thatwas linked to hair growth of the follicles.However trials are still underway to see if bimatoprost can helptreat hair loss for both males and females. Although it wasalready FDA approved to stimulate eyelash growth, what thestudy hoped to achieve is to establish that the drug can also beused for the scalp since the two have varying characteristics.
  • Scalp hair has the tendency to be extra sensitive to hormonalchanges, particularly with fluctuations in testosterone levels,which by the way is also applicable for the ladies. Eyelashes onthe other hand are not affected by these changes.In order to test the effect of bimatoprost on other hair types, theresearchers performed three types of experiments. One sampletested bimatoprost on human cells that were grown in culture, theother are cells from the human scalp, and the third was done onthe skin on the bald areas on mice.Their results showed that all three came up with hair growth afterit was treated with Bimatoprost.With male pattern baldness, androgens signal specific pathwaysthat are linked to baldness by filling in on certain receptor siteson the cells. When the connection occurs, it acts like a switch hasbeen turned on, hardwiring the cells to adapt a certaincharacteristic. What bimatropost does is to signal the cells of thehair follicles to act oppositely thereby blocking progressive hairloss.What the researchers are hoping is that the effects of bimatoprostwould be much stronger compared to androgens. If so, this wouldmake a new and very promising treatment for hair loss.This is not the first drug that was manufactured to treat onecondition which eventually showed helpful side effects when itcomes to hair loss. Viagra for instance, which was originallymarketed to treat erectile dysfunction was also discovered toimprove hair growth. Minoxidil, which was also used primarilyfor the treatment of benign prostatic hyperplasia (BPH), is alsoknown to be a popular hair loss medication today.The phase II of the study is still underway, and results areexpected to be released before the year ends.
  • Dr Andrew Kim, MDHair Transplant SurgeonDr Andrew Kim is the founder andMedical Director of Australian Instituteof Hair Restoration, a clinic specializingin surgical hair restoration.He has a team of highly-skilled hairtransplant technicians who address theneeds of their clients after a thoroughconsultation.They operate in variouslocations in Australia including Sydney,Melbourne, and Canberra.For more information on protecting,enhancing and restoring your living andgrowing hair, call 1300 733 092, or learnmore online at