For major surgery, regular insulin is administered intravenously in an infusion of 10% of dextrose in 1/2NS to which potassium chloride has been added (0.3 units of regular insulin per gram of glucose) and infused at 100ml/hr. (15units for one pint)
Patients with diabetes should receive approximately 5 g of glucose per hour (i.e., 5 % dextrose solution in water infused at 100 mL per hour) during surgery to prevent the development of hypoglycemia, ketosis, or protein breakdown.
Type I diabetics who undergo minor surgical procedures should have their blood sugars checked every 4 hours. If the blood glucose levels is >250 mg/dl, subcutaneous (SC) rapid acting insulin should administered.