Mycotic mastitis

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Mycotic mastitis

  1. 1. K.KARTHIK, 5070, VBM.
  2. 2. MASTITIS • Inflammation of udder Causative agents include • Bacteria • Fungi • Algae,etc.,
  3. 3. INTRODUCTION • Associated with over 26 species • Candida spp., Aspergillus spp., Trichosporon spp., Cryptococcus spp., Saccharomyces spp., Penicillium spp., etc. (CARTER, 1995). • Fungi as the cause of mastitis -Rolle (1934), isolated yeasts from five cows being fed on brewery by-products. • Candida is the most common species isolated (Radostitis, 1995).
  4. 4. • Yeasts and Actinomycetes seem to be best adapted to growth in the ducts and acini of the udder yeast yeast actinomycetes
  5. 5. SYMPTOMS • Gradual development of swelling (Pounden et al .,1952) • Loss of appetite and a rise in temperature but absence of toxaemia (Simon et al.,1953) • Swelling in all four quarters within 12 hours (Galli ,1954)
  6. 6. MILK • Greyish or yellowish floccules have been reported – yeasts (Andersen & Jorgensen, 1949) • A mucilaginous secretion - cryptococcal infection
  7. 7. MASTITIS - GOAT Markedly enlarged (about 2 times) right (R) infected Markedly swollen and enlarged right udder half (R) goat 24 hrs after infection with Candida albicans.
  8. 8. HISTOPATHOLOGY • Marked neutrophil infiltration • Phagocytosed spores within the macrophages • Extensive fibrosis in the interlobular septa dividing the lobules
  9. 9. • Pseudohyphae and budding yeasts of C. albicans mixed with purulent exudate in the lumina of acini
  10. 10. Geotrichum candidum • Keratinophilic yeast • Extremely rare (mishra and panda, 1986;seddek, 1997; krzyzanowski and sielicka, 1996). • Any injury to teat sphinctures, or unhygienic milking, can lead to its entry. • Milk-watery with thick flakes, and slightly blood tinged
  11. 11. • Microscopically the fungal mycelia were septate and some were fragmented into rectangular arthrospores • Sensitive only to amphotericin-B.
  12. 12. DIAGNOSIS • Strip cup test – change in colour,consistency • Isolation and identification aspergillus candida
  13. 13. cont cryptococcus penicillum
  14. 14. CLINICAL IMPORTANCE • Administration of antibiotics may aggravate fungal mastitis as Candida spp. utilize penicillin and tetracyclines as a source of nitrogen (Meek, 1981). candida antibiotic
  15. 15. TREATMENT Antifungal drugs like:- • Nystatin , natamycin – for yeast mastitis • Amphotericin B – geotrichum

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