( Ref. Bureau of Epidemiology,DDC,MOPH : Hepatitis )
Hepatitis B Virus (Form 506 : B12) ( Ref. Bureau of Epidemiology,DDC,MOPH : Hepatitis ) Prevalence of HepatitisB By year 1997 to 2006 Per 100,000 population Report Case of Hepatitis By year 2006 Age group Per 100,000 population
Hepatitis B Virus (Form 506 : B12) ( Ref. Bureau of Epidemiology,DDC,MOPH : Hepatitis ) Report case of Hepatitis B By region year 2006 Per 100,000 population Report Case of Hepatitis By Type of HAV , HVB Year 1997 to 2006 Per 100,000 population
Province specific incidence 2006 ( Ref. Bureau of Epidemiology,DDC,MOPH : Hepatitis ) Report Case of Hepatitis per 100,000 population By Province , 2006
Thailand : EPI for Children ( Ref. who.int/immunization_monitoring/en/globalsummary/countryprofileresult )
Virus attaches to host receptors through major surface antigen and enters the cell by an unknown mechanism.
Relaxed circular DNA ( RC - DNA ) and capsid are transported via microtubules to the nucleus where DNA is released through the nuclear pore, and repaired to form covalently closed circular DNA ( cccDNA ).
Transcription by RNA polymerase II of the pregenomic RNA (pgRNA) and subgenomic mRNAs, inducing synthesis of all the viral proteins.
pgRNA is encapsidated, together with the P protein, and reverse-transcribed inside the nucleocapsid in (-)DNA covalently linked to P protein.
(+) DNA synthesis from the (-) DNA template generates new RC - DNA .
Transport to the nucleus of new RC - DNA leads to cccDNA amplification; alternatively, the RC - DNA containing nucleocapsids are enveloped and bud as virions .