INTERNAL MEDICINE<br />
Parkinson's disease<br />Def:<br />Parkinson's disease is a degenerative disorder of the central nervous system that often...
Parkinson's disease<br />Causes:<br />Idiopathic <br />Drugs- reserpine, tetrabenazine<br />Toxins- manganese, carbomonoxi...
Parkinson's disease<br />Clinical feature:<br />Trembling of hands, arms, legs, jaw and face <br />Stiffness of the arms, ...
Parkinson's disease<br />Investigation:<br />Serological test for syphilis<br />CT<br />
Parkinson's disease<br />Management:<br />A)Any identifiable causes should be treated<br />B)Drug therapy-<br />Anticholin...
Parkinson's disease<br />Management:<br />C)Surgery- stereotaticthalamotomy<br />D)Physiotherapy<br />E)Rehabilitation<br />
5 parkinson's disease
5 parkinson's disease
5 parkinson's disease
5 parkinson's disease
5 parkinson's disease
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5 parkinson's disease

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Parkinson's disease

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5 parkinson's disease

  1. 1. INTERNAL MEDICINE<br />
  2. 2. Parkinson's disease<br />Def:<br />Parkinson's disease is a degenerative disorder of the central nervous system that often impairs the sufferer's motor skills, speech, and other functions.<br />
  3. 3. Parkinson's disease<br />Causes:<br />Idiopathic <br />Drugs- reserpine, tetrabenazine<br />Toxins- manganese, carbomonoxide<br />Viral infection- post encephalitic condition<br />Truma- repeated head injury<br />Rarely neurosyphilis<br />
  4. 4. Parkinson's disease<br />Clinical feature:<br />Trembling of hands, arms, legs, jaw and face <br />Stiffness of the arms, legs and trunk <br />Slowness of movement (bradykinesia)<br />Poor balance and coordination <br />
  5. 5. Parkinson's disease<br />Investigation:<br />Serological test for syphilis<br />CT<br />
  6. 6. Parkinson's disease<br />Management:<br />A)Any identifiable causes should be treated<br />B)Drug therapy-<br />Anticholinergic agent- Benzhexol 1-5 mg 8 hrly or Phenadrine 50-100 mg 8 hrly<br />Selegiline 10 mg in morning<br />L-dopa+carbidopa 4:1 <br />Bromocriptine(Dopamine receptor agonist)<br />
  7. 7. Parkinson's disease<br />Management:<br />C)Surgery- stereotaticthalamotomy<br />D)Physiotherapy<br />E)Rehabilitation<br />

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