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Beyond the Business Plan ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Presentation starts on next page For more information: Yali Friedman, Ph.D. [email_address] www.BuildingBiotechnology.com
Beyond the Business Plan Managing unexpected risks in biotechnology business development Yali Friedman, Ph.D. – info@thinkbiotech.com
Beyond the Business Plan ,[object Object],[object Object],[object Object]
Business risks ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Freedom to operate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  Chp 7, p. 267
Amgen v. Transkaryotic:  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p. 120
Monsanto hit by submarine patent ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p. 126
Manufacturing problems ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  pp. 202, 346-7, 161
Lessons ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
If you build it, they might not come ,[object Object],[object Object],[object Object],[object Object],[object Object]
Evacyte: Classic technology push ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  pp. 264-265
Calgene’s Flavr Savr tomato ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p. 326
Path to development ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Market launch ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Why do companies aim for empty markets? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Estimating market size ,[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  pp  235-239, 273-276
Resolving valuation disagreements ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p 304
Low estimates can be detrimental ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p 275
Lessons ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Off-label use ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  pp 148-150
Fen-Phen: Yes, you can be too popular ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p 150
Fentora: Don’t buy our drug ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p 148
Avastin: Controlling off-label use ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p 282
Lessons ,[object Object],[object Object]
Shareholder / board activism BUILDING BIOTECHNOLOGY  pp. 193-197
Dyadic:  Et tu Brute ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Shareholder letter
Founder regains control … of what?
MedImmune: Shareholder activism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  pp. 195
With partners like these, who needs competitors ,[object Object],[object Object],[object Object],[object Object],[object Object]
Suing the Red Cross ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p 131
IP disputes with major backers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  p 186
Nektar: Running with the big dogs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BUILDING BIOTECHNOLOGY  pp.250-251, 308
Lessons ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The business plan is but the beginning ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Yali Friedman – info@thinkbiotech.com
Building Biotechnology on Facebook ,[object Object],[object Object],[object Object],[object Object],[object Object]

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