Werner's syndrome is a premature aging disease that begins in the early adult hood, and results in appearance of characteristics of the body.
. How is it inherited? It is inherited and transmitted from there parents and is a recessive trait. The people with this syndrome tend to live shorter lives because their cells die faster then normal people.
Some of the Symptoms Physical characteristics include short stature wrinkled skin, baldness, cataracts, muscular atrophy, wrinkling and sagging in the face, decreasing of muscle mass, thin skin loss of fat under skin, graying of hair, high-pitched voice, ect… The organs in the body also start to age as well causing weak bones, type 2 diabetes, rare cancers heat and artery disease, ect….
How it's tested The doctors start by monitoring and assessing the symptoms. They monitor the sings such as hair loss and skin discoloration. Then they have to take blood tests. They also have to genetic testing, to see if there are any mutations in the WRN gene.
Occurrence of the disease About one in every 200,000 people in the U.S. may have Werner syndrome. Werner syndrome is somewhat more common in Japan, about one in 30,000 people may have it. People that have family with werner syndrome are at a higher risk of getting it.
Treatment or no treatment There is no known treatment for werner syndrome, there are ways that you treat specific symptoms. Like your skin you could get skin graphs done.
They first used yeast to test it,because it is like our WRN protein.
often referred to as a progeroid syndrome
They typically don’t develop normally until they reach puberty.
After puberty they rapidly start to age.
Their facial appearance described as "bird-like when they reach age 30.
Werner’s syndrome is found on chromosome eight.
Usually only live to be in their late forty’s early fifties.
There was a report of two siblings with werener syndrome the first was diagnosed at age 20 and the other at age 16. they first noticed some of the early symptoms like graying hair, short stature and other things. During the 12 year follow-up period, gray hair, high-pitched voice, steatohepatosis, and osteoporosis had developed
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