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Our story of understanding of what its like  living with diabetes
 

Our story of understanding of what its like living with diabetes

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The journey of the development of the Diabetes Health Profile

The journey of the development of the Diabetes Health Profile

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    Our story of understanding of what its like  living with diabetes Our story of understanding of what its like living with diabetes Presentation Transcript

    • THE DIABETES HEALTH PROFILE (DHP)DEVELOPMENT JOURNEY1986Initialdevelopmentof the DHP-1Patient input25 In-depth patientinterviewsLiteraturereview +DHP Conceptual modelThe DHP-1 and DHP-18 are standardised diabetes-specific measures of the impact of diabetes on psychological andbehavioural dysfunctioning in Type 1 and Type 2 diabetes respectively. Compliant with FDA guidelines on PRO developmentsfor label claims.
    • Through a combination of factor analyses, internal reliability, construct, convergent and discriminantvalidity the 32-item DHP-1 conceptual framework is defined for Type 1 & Type 2 Insulin requiring patients.Compliant with FDA guidelines on PRO developments for label claims.• Meadows et al 1996; Qual Life Res; 5: 242-254; Goddjin et al. 1996; Qual Life Res; 5: 433-4421986-1996DHP-1Conceptualframeworkdevelopment
    • 1996-2000DHP-18ConceptualframeworkdevelopedFrom the original 32-item DHP-1 the 18-item DHP-18 conceptual framework is derivedfor use with Type 1 and Type 2 diabetes including insulin, oral and diet. Compliant withFDA guidelines on PRO developments for label claims.• Meadows et al. Diabetic Med 2000; 17: 572-580.
    • Type 1 & Type 2RespondentsHave completed theDHP-1 / DHP-18More than2000-2013Current& previoususers of theDHP-1/DHP-18
    • 40 45 50 55 60OralInsulinDisinhibetedeatingPsycholigicaldistressBarriers toactivityScore 0=No dysfunctioning p<0.050%10%20%30%40%50%60%70%80%90%100%35-44 45-54 55-64 65-74 >75Patients reportingseverehypoglycaemicepisodesMeanage63.9years91% Type 2 and 9% Type 1patients completed thequestionnaire.Patients (mean) scores on theDisinhibited eating domain byBMIBMI<25BMI25-34BMI>3555% 45%47.849.252.4PsychologicaldistressMOST AT RISK• Comorbidity• Severe hypoglycaemia• Female• > Age• Visit to the pyschiatristANOVA p=0.05An example of what the DHP-1/DHP-18 can tell usSource: Boini et al. Health and Quality of Life Outcomes; 2010; 8:124Psychological distress3173
    • 2013NewDevelopmentsInvestigating theminimally importantdifference of theDiabetes HealthProfile (DHP-18) andthe EQ-5D and SF-6Din a UK diabetesmellitus populationForthcoming research articleFor licensing enquiries contact Isis OutcomesEmail: Healthoutcomes@isis.ox.ac.ukTel: : +44 (0)1865 280857www.isis-innovation.com/outcomes/For further information on the Diabetes Health Profile visitwww.diabetesprofile.comEmail:info@dhpresearch.comCopyright DHP Research & Consultancy Ltd 2013 . All rights reservedDiabetes Health Profile(DHP) LicensingAssociation withIsis Outcomes.Develops eDHP