In some patients, mitral regurgitation could be treated percutaneously by placement of a device in the coronary sinus via a catheter.
Placement of the prosthetic device pushes the support structures of the mitral valve and its leaflets back into more normal alignment, mimicking a surgical annuloplasty.
The prosthesis is a metal bar, about 7 cm in usable length and 1.5 mm in diameter, flexible at both ends and stiff in the middle.
Guided by fluoroscopy and transesophageal echocardiography, the bar is positioned within the coronary sinus, near the posterior valve annulus.
By exerting pressure on the dilated annulus and pushing it and its attached leaflet closer toward the other leaflet, the device helps restore more normal valve alignment and hemodynamics.
The catheter resides within the coronary sinus The prosthesis (shown within catheter) straightens the natural curvature of the vein and exerts pressure on the dilated annulus, pushing it and its attached leaflet forward to help restore more normal valve leaflet alignment. *Evalve, Inc.
Percutaneous coronary intervention (PCI), commonly known as coronary angioplasty or simply angioplasty, is a therapeutic procedure to treat the stenotic (narrowed) coronary arteries of the heart found in coronary heart disease.
These stenotic segments are due to the build up of cholesterol-laden plaques that form due to atherosclerosis.
Percutaneous coronary intervention can be performed to reduce or eliminate the symptoms of coronary artery disease, including angina (chest pain), dyspnea (shortness of breath) on exertion, and congestive heart failure.
PCI is also used to abort an acute myocardial infarction, and in some specific cases it may reduce mortality.
Coronary artery bypass surgery, also coronary artery bypass graft surgery, and colloquially heart bypass or bypass surgery is a surgical procedure performed to relieve angina and reduce the risk of death from coronary artery disease.
Arteries or veins from elsewhere in the patient's body are grafted to the coronary arteries to bypass atherosclerotic narrowings and improve the blood supply to the coronary circulation supplying the myocardium (heart muscle).
This surgery is usually performed with the heart stopped, necessitating the usage of cardiopulmonary bypass; techniques are available to perform CABG on a beating heart, so-called "off-pump" surgery.
It is the world’s first and only FDA-approved Total Artificial Heart.
Originally designed as a permanent replacement heart, it is currently approved as a bridge to human heart transplant for patients dying because both sides of their hearts are failing (irreversible end stage biventricular failure).