Global Dementia Legacy Event: Mr. George Vradenburg

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Session Four: Exploring the financial mechanisms that can be harnessed to increase investment in
dementia.

Mr. George Vradenburg, Convenor, The Global CEO Initiative on Alzheimer's and Chairman of USAgainstAlzheimer’s & World Dementia Council Member

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Global Dementia Legacy Event: Mr. George Vradenburg

  1. 1. George Vradenburg Convener, The Global CEO Initiative on Alzheimer’s Disease Member, World Dementia Council 1
  2. 2. Mobilizing the Needed Resources Increasing our Productivity Increasing Investor Reward/Reducing their Risk Innovative Finance Mechanisms and Approaches 2
  3. 3. Increasing our Productivity Global Alzheimer’s Platform 3Examples only, not comprehensive U.K. Dementia Platform Global Goals: Longitudinal Data, Biomarkers/Diagnostics, New Targets, Reduce Time/Cost to Market, Regulatory Alignment
  4. 4. Increasing Investor Reward/Reducing Risk 4 Mechanism Example Reward: Extension of Exclusivity/IP Period Orphan Drug Policy Changes Risk: Shortening Development Times HIV/AIDS; Biomarkers + Conditional Approval; Trial- Ready Infrastructure Both: Reduce Uncertainty Accelerated and Globally Aligned Regulatory Pathways ►Here are mechanisms to change the risk/reward equation ►Each has been done elsewhere; we can do it
  5. 5. Drug Discovery/ Diagnostics Care Delivery Venture Capital Drug Development Arc of Disease Management Finance Mechanisms - Today Government Grants 5 Non-Profit, Philanthropy Industry Private Equity Hedge Funds Today Innovative Finance Mechanisms and Approaches Basic Research Government
  6. 6. Drug Discovery/ Diagnostics Care Delivery Basic Research Venture Capital Drug Development Arc of Disease Management Finance Mechanisms – In The Future Government Grants 6 Non-Profit, Philanthropy Industry Private Equity Hedge Funds Future Government Sovereign Wealth Crowd Funding Global Fund Social Impact Bonds Crowd Equity
  7. 7. Government Drug Discovery/ Diagnostics Care Delivery Basic Research Venture Capital Drug Development Arc of Disease Management Finance Mechanisms – In The Future Government Grants 7 Non-Profit, Philanthropy Industry Private Equity Hedge Funds Future Crowd Funding Global Fund Crowd Equity Non-Profit, Philanthropy & Venture Capital Global Fund & Government & Industry Sovereign Wealth Social Impact Bonds Government & Private Equity
  8. 8. THANK YOU 8 Maike Stenull, Johnson & Johnson Luc Truyen, Janssen (a Johnson & Johnson Company) Cynthia Duggan, New York Academy of Sciences The Member Companies of The Global CEO Initiative on Alzheimer’s

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