Transcript of "Welcome to Hyper-MED Australia Hyper-Med is an emerging ..."
Welcome to Hyper-MED Australia
Hyper-Med is an emerging biotechnology company committed to the future commercialization of a unique
and leading-edge process of treating degenerative and chronic illness through the regeneration of body
cells referred to as integrated neuroplasticity for neurovascular and cellular regeneration.
Hyper-Med has developed proprietary protocols including Hyperbaric Oxygenation, Advanced Vibration
Training (Oxy-Vibe), Stem Cell therapies and emerging neuro-robotic rehabilitation in the treatment and
management of complex neurovascular disorders including spinal cord injury, chronic pain syndromes,
failed back surgery, stroke, traumatic brain injury, multiple sclerosis, cerebral palsy, chronic fatigue
syndromes and chronic illness.
The Hyperbaric Foundation of Australia has also been established for clinical research cases and individuals
with financial hardship. Additional information regarding the Foundation is available on our website.
The clinical application is not a recent start-up but has built on a proven proprietary system of treating
complex orthopaedic, neurological and degenerative illnesses. Hyper-Med Australia incorporates the
trading identities of Spinal Rehabilitation Group (established 1986) and Melbourne Hyperbaric; being the
first facility in Australia to incorporate the merits of Hyperbaric Oxygenation in the treatment and
management of degenerative neurovascular disorders. Spinal Rehabilitation Group was primarily focused
on medico-legal consultation and the first group to offer a multidisciplinary approach in the treatment of
How did we get into this?
Dr Hooper quotes, during 1993 one of our six children at 18-months of age; fell into a fire and suffered
extensive burns to her arms, hands, stomach and knees. The ordeal was overwhelming; extensive donor
skin grafts were recommended being cautioned that without grafts Rachael would end up with a
permanent disability because the burns region was ischemic and that extensive scarring would lead to
significant contractures and deformity.
I was compelled as both father and practitioner to provide the best possible outcome for our daughter; we
used a range of immune stimulating supports including low level laser and together with continuing prayer
– thank God; she did not require grafts and in fact the scarring continues to subside. Rachael has emerged
as a very determined and focused young lady with a magnificent drive that has excelled her in sporting
achievements competing at both state and national levels.
Subsequent to this ordeal and continuing the search for applications to promote blood supply and reduce
scar formation I discovered Hyperbaric Oxygenation (HBOT) and the growing clinical application of
conditions being treated. I was aware that Hyperbaric was the treatment of choice for diving related illness
but I was amazed by the enormity of publications and trials being conducted world-wide ranging from
brain injury, delayed wounds, chronic immunosuppressive disease to cancers! In fact the use of Hyperbaric
Oxygenation for burns victims is a standard protocol in Russia and has been for the past 20-30 years.
However, the Australian Medicare did not and continues NOT to recognize what appears to be a major
break-through with potential to significantly alter the cause and effects of many disease processes.
Currently only 6-conditions attract Medicare rebate!
Spinal Rehabilitation Group was predominantly a multi disciplinary group providing medicolegal specialty.
It was common place for our referral patients with complex spinal disorders to be directed for the most
advanced diagnostic procedures and clinical investigations which included MRI to determine the exact
nature of the underlying spinal condition. My own clinical research continued; the fact that back and
related problems continue to get worse as a direct result of diminishing blood supply (ischemia) regardless
of the surgical approach, drug, magic potion or rub; lead to the hypothesis that perhaps Hyperbaric
Oxygenation may impact spinal disorders. Clinical publications confirmed that Hyperbaric corrects and
alters tissue hypoxia which is responsible for chronic edema and swelling; then perhaps HBOT may impact
the long term effects of chronic spinal pain syndromes and other degenerative neurological conditions.
Our first chamber was commissioned during 1995 and our pioneering work began. The application of
Hyperbaric Oxygenation in the treatment and management of spinal injury including chronic pain
syndromes associated with single and multi-level disc protrusion, canal stenosis, failed back surgery etc
has provided enormous benefit to now many thousands of patients.
Since commencing Hyperbaric Oxygenation (HBOT) in excess of 60,000 separate chamber sessions have
been performed without incident and with virtually all conditions NOT covered under the Medicare and or
Third Party Insurers. However the service provision continues to grow with in excess of 75% of patients
attending from interstate and overseas.
Currently we have 4-state of the art monoplace chambers in operation. Unlike hospital based hyperbaric
chambers; each patient is treated as an individual – you are NOT pressurized with another patient.
Hospital based chambers usually have a number of patients all in a large multi-place chamber with every
occupant going to the same depth. If one of the occupants has an ear problem or cannot pressurize then
the entire procedure is aborted!
In addition; Medicare approved conditions are typically highly infective disorders and require the patient to
receive HBOT at pressures greater than 2.8 ATA and beyond. This is NOT appropriate for chronic
neurological disorders and in fact can provide considerable risk to the neurovascular patient. Our protocol
uses lower pressures which are tailored to the patient’s individual requirements; based on MRI and clinical
investigations. HBOT provided is safe, non-invasive and provides no risk to degenerative neurological
patients. Each chamber has its own TV/DVD which provides a great opportunity to relax, enjoy the time
whilst receiving treatment specific to your needs!
We continue to focus our clinical efforts towards complex neurovascular disability including:
Complex spinal pain syndromes due to failed back surgery, spinal disc protrusion (single; multi level),
degenerative spondylolisthesis, degenerative arthritis, traumatic sports injuries, vascular diseases of the
spinal cord, peripheral neuropathy (sciatica), neuro-vascular crush injury, acute compressive and chronic
spinal cord injury (paraplegia; quadriplegia), radiation myelitis, crush-compartment syndrome, closed
head injury, acute and chronic cerebral edema, cerebral palsy, autism, delayed development syndrome,
epilepsy; multi-infarct dementia, vascular migraine, brain abscess, stroke victims, chronic illness, chronic
fatigue syndrome and immunosuppressive illness, opportunistic infection, multiple sclerosis, Parkinson’s
disease, Alzheimer’s disease, degenerative motor neuron disorders, amyotrophic lateral sclerosis,
vegetative coma, asphyxiation - drowning, near hanging, acute cardiac shock and insufficiency, myocardial
ischemia, all stages of cardiac surgery and recovery, blood loss anaemia; complex fractures including
delayed and non-union fractures, osteomyelitis, bone grafts, osteoporosis, prosthesis, peripheral vascular
disease, chronic delayed wound healing, gangrene, ischemic leg pain, frost bite, amputation, post surgical
compromise, flap repair, gastro-intestinal disorders - ulcers, bleeding, diverticulitis, enhancement of
radiosensitivity in cancer, post radiation and chemo recovery, cancer immuno-support and recovery …
All patients are thoroughly investigated prior to commencing our programs and may include MRI (Magnetic
Resonance Imaging) brain and full spine; SPECT (Single Photon Emission Computed Tomography), PET CT
Scan (Positron Emission Tomography with CT Image); and blood tests using PCR-DNA (Polymerase Chain
Reaction) investigation for underlying ‘opportunistic infections’ identified as potential ‘triggers’ associated
with the degenerative cycle.
Opportunistic infections identified with chronic illness and degenerative neurovascular disorders including
chronic pain syndromes due to failed back surgery include: Chlamydia profile, Mycoplasma profile, Epstein
Barr virus, Cytomegalovirus, Herpes profile, Rickettsia profile, Toxoplasmosis profile etc - blood is drawn at
a research lab for clinical examination and reporting. In addition; full immune and integrative related
molecular factors are tested including T Lymphocytes profile, Natural Killer Cells, Cancer markers; and
Heavy Metal toxicology investigating hair, blood and urine.
Chronic bacterial and or viral based infections can be actively involved in virtually all disease processes
ranging from heart, diabetic and stroke related conditions to patients suffering complex neurological
disease including multiple sclerosis, motor neuron disease, and even individuals with a simple bad back!
Numerous clinical studies have identified the involvement of chronic infections. In order for bacterial and
viral based activity to survive they must take residence in tissue structures of the body that has ‘low
oxygen efficiency’ known as an ‘anaerobic’ site. This is a process that occurs over time as a direct
consequence of blood supply to the specific tissue structure being compromised. Tissue structures that are
deficient in the normal supportive blood flow, resulting in less than normal vital oxygen efficiency is known
as ‘hypoxia’. MRI and other specific investigations can correctly identify the potential of hypoxic sites,
which in turn; fosters a 'host’ site for potential bacterial and viral replication.
An example of this is Multiple Sclerosis. Needle biopsy of the ‘active’ lesions identified on MRI
investigations using PCR-DNA methods have correctly identified both bacterial and viral involvement
including Chlamydia pneumonia, Epstein Barr virus, Cytomegalovirus and even Herpes related viral strains.
Clinical studies have identified the fact that many bacterial and viral based infections are extremely
opportunistic and referred to as: 'opportunistic DNA infections'. This means that they actually invade into
the weakened cell and replicate in the DNA of the host cell accelerating the destructive cycle of the disease
and or degenerative process. In the case of MS and numerous neurovascular disorders – ‘bad bugs’ are
actively involved in the disease process weakening the nerve and blood vessel wall.
Tissue biopsy and PCR-DNA analysis of MRI identified back problems; again have identified the relationship
of various bacteria including Mycoplasma infection as well as a number of other bacterial and viral based
MRI is essential to establish the exact nature of the joint and integrity of spinal cord and or the brain
structures concerned. Investigations including PCR-DNA blood tests for underlying infection will enable us
to correctly identify the bacterial and viral ‘load’ within the patient and enable us to appropriately medicate
and monitor the progress of each individual patient whilst undergoing treatment. When the ‘triggers’ are
identified and correctly dealt with, the potential for long-term success and stability is dramatically
increased and easily maintained. Unless dealt with the underlying triggers continue their cycle of
destruction and ultimately the individual emerges with an established disease profile, as they get older!
Hyperbaric Medicine (also known as Hyperbaric Oxygen Therapy or HBOT) is a method of safely delivering
high doses of 100% Oxygen to the body while inside a pressurized chamber. Most treatments to enhance
immune responses, athletic performances and the effective treatment of chronic degenerative neurological
conditions are safely performed between 1.75-2.0 ATA.
Hyperbaric works by increasing the saturative effect of dissolved oxygen into the blood and surrounding
tissue structures that have been deprived of vital oxygen (hypoxic tissue). The pressure inside the
chamber causes the Oxygen breathed to be dissolved at greater levels in the blood. Recent studies have
reported that HBOT results in about a 15-20 fold increase in oxygen saturation. This is about a 2,000%
increase of dissolved oxygen into the brain and spinal cord structures!
Approximately 20-30% of the body's consumption of Oxygen occurs within 3-5% of the body mass - the
brain and spinal cord. These structures are extremely sensitive to Oxygen deficiency, and can have the
most dramatic results with the use of HBOT. This increased tissue Oxygenation significantly accelerates
the rate of healing, stabilization and repair.
• HBOT is non-invasive. It is not a surgical procedure
• HBOT is safe
• HBOT works extremely well with other forms of physical therapies and or requisite medications. It
enhances the effectiveness of both traditional and complimentary therapies
Hyperbaric Oxygen Therapy mobilizes the patients own circulating Stem Cells
[Abstract published American Journal Physiology - Heart and Circulatory Physiology (Nov 05)] reports a
single 2-hour exposure to HBOT at @ 2 ATA doubles circulating CD34+ progenitor stem cells and at
approximately 40-hours of HBOT; circulating CD34+ cells increases eight fold (800%)!
Hyperbaric Oxygenation provides a fertile platform for mobilizing the patients own stem cell capacity whilst
preparing the body for further stem cell implantation techniques.
Hyperbaric Oxygen Therapy Benefits
• Mobilizes the patients own circulating stem cells providing a fertile neurovascular platform for
further stem cell related therapies and implantation
• Elevates the amount of dissolved Oxygen into compromised and damaged tissue structures.
Accelerates recovery and promotes stabilization of individuals suffering complex and progressive
neurodegenerative illness and disease
• Enhances immune capabilities - increasing white blood cell (WBC) and Natural Killer Cell (NK)
function; accelerating wound healing and infection control. This has a ‘killing’ effect which
dramatically raises the potential to fight chronic infection and overcome delayed healing
• Accelerates new tissue formation (fibroblast and collagen synthesis) essential for repair –
ligaments, disc, muscle and bone structures
• Increases blood flow into retarded tissue by fostering new blood vessel capillary growth into the
damaged and compromised areas. This is called neovascularization
• Activates damaged and non-functional neurons (nerve cells). This is extremely important in
chronic injury including spinal cord, brain injury and neurologically impaired patients. Chronic
swelling and inflammation deprives vital Oxygen, which results in nerve cells becoming abnormally
low in metabolic function. In fact, in many spinal cord and brain injured patients’, nerve cells are
not completely severed but remain intact. However, the nerve cells are ‘non-functional’ because of
the massive swelling that ultimately results in progressive scar formation because of Oxygen
deprivation. Studies have demonstrated by raising the amount of Oxygen efficiency into the
damaged area scar formation is reduced, blood flow is improved and dormant, non-functional and
damaged nerve cells can be reactivated. Obviously, the best outcome is to start with aggressive
HBOT in the early stages of injury
• Reinstates normal lymphatic drainage creating a ‘clearance’ effect reducing chronic swelling which
causes painful inflammation
• Many prescribed drugs, antibiotics and immune stimulating vitamins and amino acids require
Oxygen and are in fact greatly enhanced with benefits of Hyperbaric tissue Oxygenation
• HBOT changes cellular metabolism by altering Oxygen deprivation towards Oxygen efficiency at a
cellular level; changing the cellular substrate from an anaerobic metabolism (energy poor) into an
aerobic metabolism (energy rich). This has a net clearance effect enabling the body at a cellular
level to detoxify and reverse the radical accumulation of toxins that ultimately mutate into
abnormal cells (including cancer cells)
• Significantly reduces the ability of chronic infections including bacterial, viral and cancer cells to
replicate and proliferate. Chronic infections do not survive in a high Oxygenated environment
Treatment varies from individual to individual. Once we have established the nature of the condition (MRI
etc) and the triggers associated (bacterial and viral) a detailed treatment regime is discussed. Most
complex conditions require an initial base line period of between 80-100 hours to change the dynamics of
the damaged region and commence some form of worthwhile recovery. Most patients suffering complex
and advanced degenerative neurovascular disorders including stroke, closed head injury, failed back
surgery etc may in fact, require several hundred hours to effect clinical change and certainly a base line of
between 100-150 hours is typically required. Blocks of short intensive durations are recommended for
Patients typically attend and receive up to 4-hours of HBOT on each day attending. 2-hours are scheduled
morning and 2-hours in the afternoon. In between the chamber sessions appropriate physical therapy
including direct acupuncture needling with high frequency stimulation, immune stimulating injections and
advanced vibration therapy are provided.
Physical therapy that accompanies HBOT generally includes direct acupuncture needling into the affected
region although this will vary from patient to patient again depending on the presenting condition. Direct
needling with high frequency electrical stimulation promotes increased ‘neurovascular’ responses into the
targeted tissue. HBOT increases the dissolved oxygen into the body, mobilizes your own stem cell
production and increases circulating stem cells which focus on repair and restoration. Clinical acupuncture
directs the increased saturative effects of combined therapies into the target tissue.
The frequency of attendance per week is based on the complexity and urgency of the condition. Interstate
and overseas patients attend daily with most Melbourne patients commencing between 1-2 days per week.
However if both time and critical outcome is the objective we have observed the best results is when the
patient attends daily!
During the initial stages of treatment the patient will experience a range of symptomatic change. The
primary objective is to stabilize the underlying instability and promote recovery. If you have very high
levels of bacterial and or viral load in your blood then part of the initial treatment (2-4 months) is to
reduce these levels requiring fairly aggressive antibiotic and or anti-viral medication. Patients will often
experience a ‘Herxheimer’ reaction after about a 4-6 week period which is the term used that describes a
‘killing effect of the pathogens’, resulting in elevation of toxic levels in the blood. This is your immune
system responding and in particular due to an elevation of your circulating stem cells!
Simply stated you may feel tired, aching, irritable, mood swings, migratory joint pains and possibly
periods of changing bowel activity. It is important that if you experience this reaction, notify us
immediately. Please ensure that if you are experiencing a ‘Herx’ reaction – do not over exert yourself.
Keep your physical activities to the minimum, drink plenty of water, get plenty of sleep, and watch your
To combat these underlying issues and reactions, we also recommend very specific immune stimulating
vitamins and amino acids including MSM (Methylsulphonmethane) and Rehab Plus (refer to Oxy-Health
section). Rehab Plus has been developed by this facility and is pivotal in enabling your body to respond at
its best maximizing the benefits of treatment including Hyperbaric Therapy. In addition other non-drug
recommendations including immune stimulating injections are recommended.
Stage 1 - Initial Saturation Phase
Initial saturation requires an absolute base line of between 40-60 hours and this is confirmed by the fact
that your circulating adult stem cells are increased 8-fold (800%) between 40-60 hours. Typically most
patients have positive testimonial between 40-60 hours which obviously reflects that we are in the right
direction. However this does NOT mean that you have stabilized the problem! Complex degenerative
neurological conditions and immunosuppressive diseases may require several hundred hours to impact the
condition and commence positive measurable outcomes with an initial base line of between 100-150
Footballers, Rugby players and other top athletes typically commence with an initial base line of between
20-40 hours to gain the initial saturative benefits with Hyperbaric Oxygenation. Continuing HBOT is based
on individual requirements associated with training intensity, competition and the invariable ‘injury list’
that often grows throughout the season!
Stage 1 varies depending on your condition and frequency that you commence HBOT. If you are attending
daily then certainly this initial saturative effect will be achieved in a 3-4 week period i.e. 4-hours HBOT
daily 5-days per week for a 4 week period equals a total of 80-hours HBOT. Patients attending 1-2 days
per week may require a stage 1 program extending for a 4-6 month period before re-evaluation.
Stage 2 - Stabilization and Reconstructive Phase
Patients having completed the baseline treatment period may require additional MRI, blood, urine analysis;
again this will vary from patient to patient. HBOT sessions are reviewed with recommendation for
continuing treatments on an individual basis and obviously financial considerations.
Typically patients receive 4-hours of HBOT on each attending day with frequency intervals ranging from
weekly to monthly. Stage 2 is a supportive recommendation maintaining the effects gained in Stage 1.
Continuing clinical improvements are still evidenced and measurable during Stage 2 however; Booster
sessions are designed to maximize the saturative effect and elevate the salvage effects of HBOT during
this prolonged period.
All patients attending on a reduced schedule i.e. Stage 2 are scheduled Booster programs on a 4-6; or 8-
10 month basis. Booster programs are short bursts of intensive treatment with the specific purpose to
impact the deeper structures increasing the salvage effects of the HBOT program.
Booster programs are daily 4-hour HBOT sessions; vitamin injections etc and typically extend for a 1-2
week block period. Booster sessions vary between 20-40 hours with recommendation based on the
complexity of YOUR condition.
What is the Future direction of Hyper-Med Australia?
Hyper-Med Australia ushers a new era in functional rehabilitation. The final frontier in the treatment of
complex orthopaedic and degenerative neurovascular disorders including brain and spinal cord injury is
focused on ‘repair and functional restoration’. Simply stated the process of neuro-plasticity and neuro-
rehabilitation is ongoing; rehab is not just learning to cope and live with disability!
Neurodegeneration will ‘boom’ as the population continues to age; drug companies continue to compete on
a highly lucrative market fueled by the fact that we as the public do not want to get old or get sick let
alone suffer a chronic neurodegenerative illness. However, there are no magical bullets, pills, lotions or
Quality of life and life expectancy are the prime focus of all practitioners devoted to the field of
neurorehabilitation and anti-aging. However, the spirally cost to maintain a failing public health care
system that is ‘crisis care’ orientated notwithstanding the fact that the vast majority of patients with
complex neuro-disability continue to get worse; has meant that medicine must look towards innovation.
The emerging field of musculoskeletal medicine and functional neurorehabilitation is focused on what is
being seen as very clear corridors of opportunity to influence patient outcomes - ‘correcting hypoxic sites;
delivery of growth factors and stem cell therapies to promote salvage and axonal sprouting; activation of
idling and non-functional neurons whilst promoting neovascularization (new capillary formation); coupled
with neuro-robotic functional gait retraining’.
Publications world wide continue to advocate the merits of continuing functional treatment and restoration
programs for victims of brain and spinal injury and those suffering progressive degenerative neurological
disorders. At the recent World Federation of Neuroplasticity held in Zurich; numerous presentations
included Hyperbaric Oxygenation, Advanced Vibration Therapy (Whole Body Vibration), Stem Cell
applications and other significant immune modulating approaches. All clinical disorders and progressive
disease can be influenced; it is hopeful that the quality of life for those afflicted may be improved as these
emerging applications become more readily available.
This future of Hyperbaric Oxygenation combined with stem cell therapies including Neuro-Robotic
rehabilitation programs; will provide a significant break-through in the treatment and management of
complex disorders and illness including brain and spinal cord injury.
Brain and spinal cord injury leads to significant disability. However, many patients improve spontaneously,
at least to some extent after the acute traumatic period; the principal mechanisms associated with the
capacity to repair and self-regenerate are referred to as brain and spinal cord ‘plasticity’. Plasticity refers
to the capability of the brain and spinal cord to undergo rehabilitative change – salvage of the damaged
area and ultimately functional restoration.
The influence of neuro-plasticity is an obvious priority in the acute stage of injury. However, evidence
demonstrates that patients with chronic disability; even years after injury can be greatly improved by
using methods and techniques focused on the underlying factors that influence the plasticity process.
There are a number of principles that determine neuro-plasticity. One is that there is continuous
competition between body parts for representation in the central nervous system (CNS). The second is the
fact that use of the body part enhances its representation and disuse leads to loss of representation.
Simply stated - use it or lose it! This is the emerging role of Automotive Functional Gait training | Neuro-
In addition; Neuro-plasticity is dependent on a number of key factors including the extent of glial (scar)
formation; integrity of supporting blood supply and tissue oxygenation; and ultimately the ability of
surviving axons in partial lesions to take over additional functions – axon sprouting. This is the emerging
role of Hyperbaric Oxygenation.
Apoptosis refers to programmed cell death; and has been identified in the destructive changes associated
with brain and spinal cord injury fostering the cycle of continued dysfunction, degeneration and ultimate
neuronal death. In fact many brain and spinal cord patients continue to get worse and this is evidenced by
additional MRIs of the region 3-5 years post the initial injury; in many cases there is further expansion of
the original primary lesion and a cascade of secondary degenerative effects.
Oxygen deprivation (hypoxia) modifies the expression of plasticity; Apoptotic bodies and DNA
fragmentations are observed in the avascular ischemic region with increased inhibitory factors (proteins)
released into the damaged parts of the brain and spinal cord. These proteins inhibit the process of
plasticity and in fact have been identified to continue programmed cellular dysfunction and ultimate death
of the damaged and compromised cell – Apoptosis.
Current research indicate that adult brain and spinal cord fibres can be stimulated in their regenerative
abilities, and that these growing fibres are able to form new circuits that mediate functional recovery even
years after the initial injury
Functional changes to dormant and inactive regions of both brain and spinal cord can be activated and
measured with fMRI which reflects an increased BOLD-response due to increased metabolic effects within
the sensorimotor systems - neuroplasticity.
Australian rehabilitation models are outdated and do NOT comply with International Standards and
certainly do not reflect methods and clinical trials available throughout the USA, England and more
importantly the rapid expansion of stem cell and related therapies NOW available in Asian Pacific countries.
Patients with significant disabilities are inadequately treated with current medical attitude focused on the
patient learning to cope and live with disability. Fortunately most individuals are now competently seeking
the internet and making discovery for themselves.
Hyper-Med Australia is focused on resolution and functional restoration; and so is the patient! We are
endeavouring to raise venture capital to acquire a worldwide break-through in the functional rehabilitation
of brain and spinal cord injured patients - robotic spinal walking. This device is NOT in available in
Australia; currently 14-units exist in the USA.
Hyper-Med is seeking corporate sponsorship, grants and financial assistance to purchase outright the
robotic walking device (Lokomat) which is currently priced at EURO $250,000 with a capital cost and
import of AUD $500,000. The Hyperbaric Foundation of Australia has been established to facilitate
We will immediately make submission to the Medicare Advisory Commission for inclusion under the Medicare
funding for spinal and neurodegenerative entitlements however this process is projected between 2-3 years
prior to approval. It is imperative that this machine is purchased outright prior to Australian delivery!
Your assistance is greatly appreciated; please contact me direct to discuss how we can accomplish this
Good luck, I trust that together we will afford you a successful outcome.
Dr Mal Hooper
13th floor 15 Collins St Melbourne 3001
T: +61 3 9650 3136