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  • Resting brain

PowerPoint Version PowerPoint Version Presentation Transcript

  • Invest in Kids Andrea McGuire, MD, MBA Chief Medical Officer American Republic Insurance Company Iowa Early Care, Health and Education Day on the Hill Feb 2007
  • Why talk about Brain Research?
    • Data Driven
    • Evidence Based
    • Findings relate to Actions
  • Early Childhood Brain Research
    • Brain Anatomy,Cellular function and neuropathways
    • Brain Research Studies of Early Childhood
    • Conclusions
  • NeuroAnatomy
  •  
  • NeuroAnatomy
  • NeuroAnatomy
    • Synapse
  • Positron Emission Tomography
  • Newborn Brain Pet Scans* * Harry T. Chugani - Biological Basis of Emotions: Brain Systems and Brain Development - Pediatrics, Nov 1998; 102: 1225.
  • 2-3 months* * Harry T. Chugani - Biological Basis of Emotions: Brain Systems and Brain Development - Pediatrics, Nov 1998; 102: 1225.
  • 8 months* * Harry T. Chugani - Biological Basis of Emotions: Brain Systems and Brain Development - Pediatrics, Nov 1998; 102: 1225.
  • Scott Grafton, M.D. - Dept. of Neurology and Dept. of Radiology - University of Southern California John Mazziotta, M.D., Ph.D. - Dept. of Molecular and Medical Pharmacology and Dept. of Neurology - UCLA School of Medicine
  • Scott Grafton, M.D. - Dept. of Neurology and Dept. of Radiology - University of Southern California John Mazziotta, M.D., Ph.D. - Dept. of Molecular and Medical Pharmacology and Dept. of Neurology - UCLA School of Medicine
  • Synapse production & pruning # synapses age in years 20 40 60 80 4 8 12 16 0 frontal lobe visual cortex
  • Plasticity Note: The listed factors are not intended to be exhaustive. Chronic stress Social interaction Methyl mercury Activity Aluminum Sensory stimulation Metabolic abnormalities (excess phenylalanine, ammonia) Essential fatty acids Cocaine Folic acid Ionizing radiation Thyroid hormone Polychlorinated biphenyls (PCBs) Iodine Prenatal infections Adequate gestation Tobacco Micronutrients, such as iron and zinc Lead Adequate protein and energy Alcohol Oxygen Detrimental or Toxic Needed for Normal Brain Development
  • Resting Scott Grafton, M.D. - Dept. of Neurology and Dept. of Radiology - University of Southern California John Mazziotta, M.D., Ph.D. - Dept. of Molecular and Medical Pharmacology and Dept. of Neurology - UCLA School of Medicine
  • Hearing Scott Grafton, M.D. - Dept. of Neurology and Dept. of Radiology - University of Southern California John Mazziotta, M.D., Ph.D. - Dept. of Molecular and Medical Pharmacology and Dept. of Neurology - UCLA School of Medicine
  • Visual Scott Grafton, M.D. - Dept. of Neurology and Dept. of Radiology - University of Southern California John Mazziotta, M.D., Ph.D. - Dept. of Molecular and Medical Pharmacology and Dept. of Neurology - UCLA School of Medicine
  • Thinking task Scott Grafton, M.D. - Dept. of Neurology and Dept. of Radiology - University of Southern California John Mazziotta, M.D., Ph.D. - Dept. of Molecular and Medical Pharmacology and Dept. of Neurology - UCLA School of Medicine
  • Later Recall Scott Grafton, M.D. - Dept. of Neurology and Dept. of Radiology - University of Southern California John Mazziotta, M.D., Ph.D. - Dept. of Molecular and Medical Pharmacology and Dept. of Neurology - UCLA School of Medicine
  •  
  • Florida State University, Center for Educational Enhancement & Development, Wil Bechman, M.D., 1998.
  • The Child Development and Public Expenditures chart source is researchers at the RAND Corporation (see Investing in our Children in section 4). Brain development curve Figure 2.4 in D. Purves, Body and Brain , Harvard University Press, 1988. Public spending on children from Table 1 in R. Haverman and B. Wolfe, "Determinants of Children's Attainments: A Review of Methods and Findings," Journal of Economic Literature , Vol. 33, December 1995
  • Conclusions
    • Window of Opportunity
    • Return on investment
    • Nurture and Protect our Children