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    CURRICULUM VITAE.doc CURRICULUM VITAE.doc Document Transcript

    • CU R R I C U L U M V I T A E NAME Robert J. Dempsey, M.D. ADDRESS office - University of Wisconsin Hospital and Clinics Department of Neurological Surgery Clinical Science Center, 600 Highland Avenue, K4/822 Madison, Wisconsin 53792 PHONE NUMBER office - (608) 263-9585 LICENSURE Licensed Medical Doctor, State of Kentucky, 1983 Licensed Medical Doctor, State of Wisconsin, 1995 BOARD CERTIFICATION Diplomate of the American Board of Neurological Surgery, 1985 EDUCATION AND TRAINING College: 1973 University of Notre Dame (Summa Cum Laude) B.S. Degree Medical 1977 University of Chicago School: M.D. Degree Surgery: 1977-78 University of Michigan Hospitals Internship Neurosurgery 1978-83 University of Michigan Hospitals Residency
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 2 ACADEMIC APPOINTMENTS 1983 Assistant Professor (full-time) Division of Neurosurgery Albert B. Chandler Medical Center University of Kentucky Lexington, Kentucky 1986 Associate Professor Division of Neurosurgery Albert B. Chandler Medical Center University of Kentucky Lexington, Kentucky 1988 Director of the Center of Excellence in Stroke Research of the Center of Aging 1989 Associate Professor Department of Anatomy and Neurobiology 1990 Medical Director Cerebrovascular Laboratory 1991 Professor Division of Neurosurgery Albert B. Chandler Medical Center University of Kentucky Lexington, Kentucky 1991 Professor Department of Anatomy and Neurobiology 1995 Professor and Chairman Department of Neurological Surgery University of Wisconsin Hospital and Clinics Madison, Wisconsin 1996 Director Multidisciplinary Stroke Program University of Wisconsin Hospital and Clinics Madison, Wisconsin 1998 Manucher J. Javid Endowed Professorship in Neurological Surgery Department of Neurological Surgery University of Wisconsin Hospital and Clinics Madison, Wisconsin
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 3 2000 Chairman Council of Clinical Chairs University of Wisconsin Madison, Wisconsin 2004 Affiliate Professor Department of Anesthesiology University of Wisconsin Madison, Wisconsin HOSPITAL APPOINTMENTS 1983 Attending Neurosurgeon Albert B. Chandler Medical Center University of Kentucky, Lexington, KY 1983 Attending Neurosurgeon Veterans Administration Medical Center Lexington, Kentucky 1984 Consultant Marymount Hospital London, Kentucky 1986 Consulting Staff Highlands Regional Medical Center Prestonsburg, Kentucky 1995 Consulting Staff Veterans Administration Medical Center Madison, Wisconsin 1995 Department Chairman and attending Neurosurgeon University of Wisconsin Hospitals Madison, Wisconsin TEACHING ACTIVITY Director, Neurosurgery portion of 3rd year Medical Student 831 Surgery Course, 1983-1995 Participant, 4th year Medical Student 841 Neurosurgery Course, 1983-1995 Participant, 2nd year Medical Student 821 Neurosciences Course, 1983-1995 Participant, Continuing Education, U.of Kentucky Family Practice Review Course, 1983-1995 Participant, County Medical Society Continuing Education presentations on Head Trauma, Stroke, and Headache, 1983-1995 Participant, “Rehabilitation Management for the Primary Care Physician” Course, 1983-1995 Instructor, Advanced Trauma Life Support Course, “Head C-spine Injury,” 1983-1995
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 4 Participant Course, Contemporary Neurosciences 605, “Eicosanoids,” 1983-1995 Member, Surgery Education Committee, 1983-1995 Scientific Program Director for Southern Neurosurgical Society Annual Meeting, 1994 Participant, Premeeting Practical Course, American Association of Neurological Surgeons and Congress of Neurological Surgeons, 1992, 1993, 1994 Program Director for Southern Neurosurgical Society Annual Post Meeting Course, 1995 Director of Resident Education, U. of Wisconsin, Department of Neurological Surgery, 1995- Participant, 3rd year Surgery Course, 1995- Organize and Teach, Medical Mission Ecuador, 1994-1995, 1998-1999 Visiting Professor, Gundersen Lutheran Medical Center, 1996 Mentor, M.D.-PhD Program, 1997- Organization and Participant, Clinical Neurosciences Course, 1998- Visiting Professor, Meditropoli Centro Medico, Quito, Ecuador, 1999 Co-Director, Review and Update in Neurobiology for Neurosurgeons Society of Neurological Surgery 1999-2004 Visiting Professor, University of Ankara, Turkey, 2000 Visiting Professor, University of Chicago, 2000 OSCE exams to students, 1999-2000 Visiting Professor, Northwestern University, 2001 Visiting Professor, Henry Ford Medical Center, 2001 Visiting Professor, University of IL-Peoria, 2001 Visiting Professor, Stanford University, 2001 Visiting Professor, University of Michigan, 2002 Visiting Professor, Rush Medical School, 2002 Secretary, Foundation for International Education in Neurological Surgery, 2002-2007 Secretary, Society of Neurological Surgeons, 2003-2007 Mentor to medical student Michelle Naylor, winner of the American Society for Neurochemistry 2003 Young Investigator Educational Enhancement Award Visiting Professor, Medical College of Wisconsin, 2003 Visiting Professor, Loyola University, 2003 Board of Directors, Interurban Society, 2004- Visiting Professor, University of Kentucky, 2004 Visiting Professor, Oregon Health Sciences University, 2004 Visiting Professor, XVIIIth Annual Marshall Lectureship, The University of Toronto, 2005 Visiting Professor, University of Illinois-Chicago, 2005 Visiting Professor, Cornell University, 2005 Visiting Professor, Rush University, 2005 Co-Director, RUNN Conference, 2005, 2006 Visiting Professor, Albany Medical School, March 2006 Visiting Professor, Peter Bent-Brigham-Harvard Medical School, May 2006 Visiting Professor, Ohio State University, May 2006 Teacher, East Central Southern African Regional Neurosurgical Training Program, October 2006 Visting Professor, University of Utah, June 2007 National Neurosurgical Representative for the Organization of Program Directors ADVISING ACTIVITY University of Kentucky
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 5 1983 Supervision and Advising of Neurosurgery Residents (five per year) 1985 Supervision and Dissertation Committee (one Ph.D. Neuroanatomy student) 1994 Supervision and Dissertation Committee (one Ph.D. Nursing student) ADMINISTRATIVE ACTIVITY AND UNIVERSITY SERVICE University of Kentucky College of Medicine Research Committee, 1984-1992; Vice Chairman, 1986 Medical Center Animal Care Subcommittee, 1985-1993 Member, Trauma Committee, UKMC, 1985-1995 Veterans Administration, Major Equipment Subcommittee, 1985-1993 Veterans Administration, Transfusion Review Committee, 1985-1995 Medical Director, Cerebrovascular Laboratory, 1986-1995 Institutional Animal Care and Use Committee, 1986-1992 Veterans Administration Pharmacy and Therapeutics Committee, 1986-1995 Veterans Administration Surgical Case Review Committee, 1986-1994 College of Medicine, Subcommittee on Research, 1987-1995 Congress of Neurological Surgeons: Resident’s Registration Committee, 1988; Luncheon Seminar Cmt., 1988-1989, 1993 Member, Ben Eiseman Surgical Scholar Award Committee, 1988-1995 Member, MRI System RFP, Evaluation Committee, 1988 Member, Surgery Education Committee, 1988-1995 Chairman, Markey Cancer Center Review Committee, 1988-1989 Director, Center of Excellence in Stroke Research of the Center on Aging, 1988-1995 Member, Review Committee of the Alzheimer’s Disease Research Center of the Sanders-Brown Center on Aging, 1989-1995 Member, Residents’ Education Committee, 1989-1995 Member, Search Committee for Director, Markey Cancer Center, 1989; Chairman, 1990 Advanced Trauma Life Support Instructor, American College of Surgeons, 1989-1995 Advisory Subcommittee of the General Clinical Research Center, 1989-1995 Secretary-Treasurer of the Kentucky Neurosurgical Society, 1989-1991 Neurosurgery representative to the Athletic Board, University of Kentucky, 1990-1995 Veterans Administration, Research and Development Committee, 1990-1994 Member, Chancellor’s Hospital Project, 1990-1994 Member, University Committee on Organ Donation, 1991-1995 President-Elect, Kentucky Neurosurgical Society, 1991-1992 Member, University Research Advisory Committee, 1992-1995 President, Kentucky Neurosurgical Society, 1992-1993, On Committee, 1995 University of Wisconsin Clinical Chairs Committee, 1995- Medical School Faculty Board, 1995- AUP Board, 1995-1996 Clinical Practice Plan Committee, 1995-1996 General Clinical Research Centers Advisory/Executive Committee, 1995- Trauma Committee, 1996- Operating Room Committee, 1995- UW Medical School Accountability Task Force, 1996-1997 UW Stroke Program, 1996- UW Medical Foundation Clinical Chairs Committee, 1996-
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 6 Education Committee, 1995- University of Wisconsin/William Middleton Veterans Hospital Dean’s Committee, 1996- Critical Care Committee, 1996- Chair, Search Committee for Department of Radiology Chairperson, 1996- Member, Search Committee for VA Hospital Chief of Staff, 1996- Member, Operating Rooms Management Committee, 1996- UW Medical School Strategic Plan Steering Committee, 1997- Executive Committee of the Department of Rehabilitation Medicine, 1997- Board of Directors, University of Wisconsin Medical Foundation, 1997- VA Task Force for Neurology and Neurosurgery, 1997- University of Wisconsin Cardiovascular Research Center, 1998- Member, Academic Compensation Committee, 1999 Member, UWMF Funds Flow & Compensation Design Team, 1999 Chairman of the Council of Chairs, 2000 University of Wisconsin Hospital & Clinics Strategic Plan – Leadership Committee, 2000-2001 Executive Committee, University of Wisconsin Medical Foundation, 2000- Steering Committee, University of Wisconsin Medical Foundation, 2000 UW Stroke Program Surgical Director Neurosurgical ICU Director Graduate Medical Education Oversight Committee Professional Conduct Committee, 2001- Statewide Markets Subcommittee, UWHC, 2004- Finance Subcommittee, UWHC, 2004- Chair, Radiology Chair Search Committee, 2004-2005 Member, Medical School Dean and Vice Chancellor for Health Sciences Search Committee, 2005 Member, UW Health-Meriter Leadership Committee, 2005- Member, Search Committee for Dean of the Medical School Chair, Society of Neurosurgeons Committee Meeting, 2005 Chair, Anesthesiology Chair Search Committee, 2006- Member, Funds Flow Committee, UW Medical Foundation, 2006- PROFESSIONAL ACTIVITY AND PUBLIC SERVICE Fayette County Medical Society, 1983-1995 Kentucky Medical Society, 1983-1995 American Medical Association International Society of Cerebral Blood Flow and Metabolism Congress of Neurological Surgeons American Association for the Advancement of the Sciences Fellow of the Stroke Council of the American Heart Association The Kentucky Neurosurgical Society, 1983-1995 Book Reviewer for Cerebrovascular Topics, Journal of Neurosurgery American Association of Neurological Surgeons Society for Neuroscience Southern Neurosurgical Society, 1983-1995 Fellow of the American College of Surgeons Frederick A. Coller Surgical Society Ad Hoc Reviewer for Journal of Neurochemistry, 1987-1988
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 7 Joint Section of Cerebrovascular Surgery of the American Association of Neurological Surgeons and Congress of Neurological Surgeons Ad Hoc Reviewer for Experimental Neurology, 1988-1991 Book Reviewer for Cerebrovascular Neurosurgery Ad Hoc Reviewer for Journal of Surgery Ad Hoc Reviewer for Life Sciences Ad Hoc Reviewer for Neurology Instructor, Marriage Preparation Course, Catholic Diocese of Lexington, 1983-1995 Research Society of Neurological Surgeons Peer Scientist Reviewer, Journal of Magnetic Resonance Imaging Program Committee, Southern Neurosurgical Society, 1991-1994 Program Committee, 17th International Joint Conf. on Stroke and Cerebral Circulation, 1992 Program Committee, Congress of Neurological Surgeons, 1992- Ad Hoc Reviewer for Brain Research Ad Hoc Reviewer for Stroke Ad Hoc Member, Head Trauma Program Project Study Section, NIH, 1993 Member, NIH, Neurology B Study Section, Special Emphasis Panel, 1993 Medical Volunteer, Rural Health Project, Habitat for Humanity, Guatemala, Central America Board of Directors, Intersocietal Commission for Accreditation of Vascular Labs., 1993- Associate Editor, Clinical Neurosurgery, 1993- Member, Executive Committee of the Joint Section of Cerebrovascular Surgery of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, 1993-1996, 1998- Chairman, Research Committee of the Joint Committee on Education of the American Assn. of Neurological Surgeons and the Congress of Neurological Surgeons, 1993-1997 Ad Hoc Member, National Institutes of Health, Neurology A Study Section, 1994 Course Director, Congress of Neurological Surgeons Annual Meeting, 1994 Executive Committee of the Stroke Council of the American Heart Association, 1994- Medical Volunteer, Rural Health Surgical Teaching, Ecuador, South America, 1994-1995, 1998, 1999, 2001, 2002-2006, Africa 2006 Chairman, Scientific Program Committee, Southern Neurosurgical Society Annual meeting, 1994, & Post Meeting Course, 1995 Elected to membership, Society of Neurological Surgery, 1996 Elected to membership, American Academy of Neurological Surgery, 1996 Elected to membership, Neurosurgical Society of America, 1996 Reviewer, Stroke, 1997, 1999, 2000 Reviewer, Journal of Neurochemistry, 1997 - Examiner, American Board of Neurological Surgery, 1997, 2003 Editor, Cerebrovascular section, Neurosurgical Focus, 1997. Moderator, Plenary Session, The Joint Section of Cerebrovascular Surgery of the American Association of Neurological Surgeons and Congress of Neurological Surgeons, 1998 Board of Directors, Foundation for International Education in Neurological Surgery, 1998 Reviewer, Annals of Surgery, 1998, 1999 Moderator, Surgical Forum, Neurological Surgery, The American College of Surgeons, 1998
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 8 Co-Chair, Scientific Committee, Joint Section of Cerebrovascular Surgery of the American Association of Neurological Surgeons and Congress of Neurological Surgeons, 1998-State Medical Society of Wisconsin, 1999 Member, National Institutes of Health, Scientific Review Committee, 1999 Reviewer, American Journal of Neuroradiology, 1999 “An Update on ACAS and Comments on Study Concerns” Dempsey R J. American College of Surgeons, October 1999 Society of Neurological Surgeons Liaison to “Review and Update in Neurobiology for Neurosurgeons” 1999 Reviewer, Neurosurgery, 2000 Reviewer, Surgical Neurosurgery, 2000 Society of Neurological Surgery Representative to Council of Medical Specialty Societies GME Program Director’s Association, 1999-2005 Chair of Basic Science - Technology Review Panel at the Section on Cerebrovascular Surgery AANS/CNS, 2000-2003 Pharmacia-Upjohn Grant Committee, Jt Section of Cerebrovascular Surgery, 2000- Representative for Neurosurgery to ABMS-ACGME Joint Conference on Resident Evaluation, 2000 Grant Reviewer, Canada Foundation for Innovation, 2000 Editorial Board, Neurosurgery, 2001-2007 Senior Editor for Basic Science, Neurosurgery, 2007- Secretary, Foundation for International Education in Neurological Surgery, 2002- Secretary, Society of Neurological Surgery, 2002- Editorial Panel, Science Times in Neurosurgery, 2002- Moderator, Society of Neurological Surgeons Meeting, 2003 International Scientific Committee organization, 8th International Conference on Cerebral Vasospasm, 2003 NIH Special Emphasis Panel, "Brain Disorders in the Developing World", Study Section, August 2003 Board of Directors, Interurban Neurosurgical Society, 2004- Member, International Outreach Committee, American Association of Neurological Surgeons, 2005- Principal Editor for Basic Science, Neurosurgery, 2006- Discussant, “Early Outcome Following Multimodality Endovascular Reserve in Acute Stroke”, American Association of Neurological Surgeons Annual Meeting, Washington D.D., April 2007 HONORS Notre Dame Scholar Award Phi Beta Kappa University of Chicago Scholarship Award Sigma Xi Scientific Research Society The Doctor Paul R. Rosenbluth Award for neurosurgical resident research, Central Neurosurgical Society, March, 1982 Winner, 1982 Residents Award from the Michigan Association of Neurological Surgeons American Medical Association Physicians Recognition Award, 1984, 1986, 1989, 1997 Winner, 1985 World Federation of Neurological Societies Young Neurosurgeon Award, The International Congress of Neurological Surgery
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 9 Continuing Education Award in Neurosurgery, the Joint Committee on Education CNS, AANS, 1986, 1990, 1993, 1996 Clinical Investigators Development Award, NIH, 1986 Fellow of the American College of Surgeons, 1987 University of Kentucky President’s Faculty Grand Award, 1988-1991 University of Kentucky Continuing Education Award in Neurosurgery, 1990 University of Kentucky Department of Surgery, Award for Excellence in Teaching, 1991 University of Kentucky Department of Surgery, Award for Excellence in Teaching, 1992 University of Kentucky College of Medicine Faculty Research Award, 1993 Alpha Omega Alpha Honor Medical Society, 1993 Master Teacher Award, University of Kentucky College of Medicine, 1994 Saint Joseph the Worker Award, Catholic Christian Brothers, 1994 American Medical Association Physician’s Recognition Award, 1994-1997, 1999-2000, 2000-2003 “Testimonio de Gratitud,” Ambato, Ecuador, 1995, 1998 Visiting Professor, University of Chicago Neurosurgery, 1996 Dean’s Award for Excellence in Health Communication, 1996 Manucher J. Javid Endowed Professorship in Neurological Surgery, 1998 Named to “The Best Doctors in America,” 1998-1999, 2002, 2005-2006 Continuing Medical Education Award in Neurosurgery, 1999-2000 Visiting Professor, University of Chicago, 2000 Honored Guest Prof. Dr. Nurhan Avman Conference, Ankara University, Turkey, 2000 Visiting Professor, Northwestern University, 2001 Visiting Professor, Henry Ford Medical Center, 2001 Visiting Professor, University of IL-Peoria, 2001 Visiting Professor, Stanford University, 2001 Visiting Professor, University of Michigan, 2002 Visiting Professor, Rush Medical School, 2002 Reconcimiento-Hospital Provincial Docente Ambato, 2002 Tribute of Gratitude, Ambato, Ecuador, 2002, 2003 Named to “America’s Top Doctors”, 2002, 2003, 2004, 2005 Named to “Who’s Who in the 21st Century”, 2002 Named to “Who’s Who Among America’s Teachers”, 2002 Named to “Madison Magazine’s Top Docs of 2002!”, 2002 Named to UW Hospital & Clinics Best Doctors, 2003 Visiting Professor, Loyola University Medical Center, 2003 Visiting Professor, Medical College of Wisconsin, 2003 Visiting Professor, University of Kentucky, 2004 AMA Physician's Recognition Award (PRA), 2003-2006 Visiting Professor, Oregon Health Sciences University, 2004 Resident Teaching Award, Department of Neurological Surgery, University of Wisconsin Medical School, 2004 Visiting Professor, XVIIIth Annual Marshall Lectureship, The University of Toronto, 2005 Visiting Professor, University of Illinois-Chicago, 2005 Sally Harrington Goldwater Visiting Professor, Barrow Neurological Institute, May 2005 Named to "Who's Who in Medical Sciences Education", 2005 Visiting Professor, Cornell Medical School, November 2005 Visiting Professor and Neurosurgery, Rush University Medical Center, December 2005 Visiting Professor, Albany Medical School, March 2006
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 10 R.M.P. Donaghy Award for Cerebrovascular Neurosurgery, Cerebrovascular Section of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, April 2006. Visiting Professor, Peter Bent-Brigham-Harvard Medical School, May 2006 Visiting Professor, Ohio State University, May 2006 Visiting Professor, University of Utah, June 2007 SPEAKING ENGAGEMENTS AND PAPERS PRESENTED Regional Enzyme Efflux from Skeletal Muscle: Reduction by Diethylstilbestrol” Dempsey R; 31st Annual Senior Scientific Session, University of Chicago School of Medicine, May, 1977. “A Method of Pinealectomy without Neurologic Deficit in Sheep: Preparation for Hormone Manipulation Studies” Dempsey R, Hopkins J, Bittman E; Society for Neuroscience Meeting, Michigan Chapter, May 30, 1981. “Pineal Gland Function: A Historical and Experimental Study” Dempsey R, Kindt G; Michigan Association of Neurological Surgeons Annual Meeting, June, 1981. “Epidural Hematoma: Experimental Parameters in Decreasing Morbidity and Mortality” Dempsey R; Michigan Association of Neurological Surgeons, June 1982. “New Surgical Treatments of Stroke” Dempsey R; 16th Family Medicine Review, University of Kentucky, 1985. “Evaluation and Treatment of Strokes with and without CAT Scans” Dempsey R; 17th Family Medicine Review, University of Kentucky, 1986. “Stroke Research and MRI” Dempsey R; Kentucky Neurosurgical Society, 1986. “The Relationship Between Carotid Stenosis and Cerebral Ischemia” Dempsey R; Kentucky Neurosurgical Society, 1987. “Stroke in the Elderly” Dempsey R; Family Practice Review, U. of Kentucky, November, 1987. “Evaluation and Treatment of the Patient with Asymptomatic Carotid Artery Stenosis” Dempsey R; Family Practice Review, University of Kentucky, November 1987. “Cerebral Infarction and the Ages of Man” Dempsey R; 19th Family Medicine Review, University of Kentucky, 1988. “NMR after Transient Cerebral Ischemia” Dempsey R, Combs D, Smith C; Kentucky Neurosurgical Society, 1989. “ICP Management in Head Injury and Stroke” Dempsey R; Visiting Professor, Maine Medical Center, February, 1991. “The Molecular Biology of Stroke” Dempsey R; Maine Neurosurgical Society, March 1991.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 11 “Head Injury Management: State of the Art” Dempsey R; University of Kentucky Trauma Symposium, June, 1991. “Noninvasive Assessment of Cerebral Atherosclerosis” Dempsey R; Kentucky Neurosurg. Soc., 1991. “Trends and Issues in the Management of Acute Head and Spinal Cord Injury” Dempsey R; University of Kentucky 3rd Annual Trauma Symposium, 1992. “Cerebrovascular Disease” Dempsey R; 1995 Chronic Disease Conference, Cabinet for Human Resources, Lexington, Kentucky, 1995. “Cerebrovascular Disease” Dempsey R; U. of Kentucky Internal Medicine Board Review, 1995. “Cerebral Protection During Aneurysm Surgery - From the Laboratory to the Operating Room” Dempsey R; Wisconsin Neurosurgical Society, 1995, Milwaukee. “Neurologic Injury in Athletes: Prevention and Treatment” Dempsey R; Progress in Pediatrics, April 1996, Madison. “Carotid Endarterectomy” Dempsey R; American Assn. of Neuroscience Nurses, May 1996, Madison. “Carotid Endarterectomy: Lessons Learned About the Prevention of Stroke” Dempsey R; Wisconsin State Neurosurgical Society, September 1996, Lake Geneva. “Diagnosis and Treatment of Aneurysms and AVMs” Dempsey R; Midwestern Neuroscience Nurses Meeting, October 1996, Madison. “Acute Stroke Care: Emergent Response” Dempsey R; Lecture to Paramedics, University of Wisconsin Hospital & Clinics, October 22 & 23, 1996, Madison. “Football Neurological Injuries: Prevention and Treatment” Dempsey R; Update in Pediatrics, October 1996, Appleton. “Diagnosis and Management of Complex Vascular Malformation” Dempsey R; at “A Multi- disciplinary Approach to the Diagnosis and Management of Stroke,” October 1996, Kohler. “University of Wisconsin Atherosclerotic Plaque Study” Dempsey R; presented at “A Multi- disciplinary Approach to the Diagnosis and Management of Stroke,” October 1996, Kohler. Member of 3 Panels, “A Multi-disciplinary Approach to the Diagnosis and Management of Stroke,” October 1996, Kohler. “Stroke: The Changing Scene” Dempsey R; at University of Wisconsin Stroke Symposium, September 1997, Madison. “Stroke: Possible Diagnoses” Dempsey R; at University of Wisconsin Stroke Symposium, September 1997, Madison.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 12 “Research Update: Current University of Wisconsin Protocols and National Trends” Dempsey R; at University of Wisconsin Stroke Symposium, September 1997, Madison. “Management of Acute Stroke” Dempsey R; 14th Critical Care Symposium, October 1997, Madison. “Stroke: Modern Diagnosis and Treatment” Dempsey R; Norwegian Club, October 1997, Madison. “Major Closed Head Injuries” Dempsey R; Sports Medicine Symposium, May 1998, Madison. “Cytoprotective Approach to Stroke” Dempsey R; Dodgeville Hospital, Iowa Co., WI, August 1998. “Head Injury-Management and Diagnosis” Dempsey R; Beaver Dam Community Hospital, Beaver Dam, Wisconsin, September 1998. “Neuroimaging in the Evaluation and Treatment of Stroke: The Role of Duplex, MRA and Angiography” Dempsey R; at University of Wisconsin Stroke Symposium, October 1998, Madison. “Stroke Acute Care” Dempsey R; Fort Atkinson, Wisconsin Memorial Hospital, October 1998. “Role of Na+-K+-2Cl- Cotransporter in [3H]-D-Aspartate Uptake and Release from Astrocytes in High [K+]o. Su G, Dempsey R, Sun D. Annual Meeting of Midwest Neurobiologists, May 1999. “Evolving a Neuroprotective Approach to Stroke” Dempsey R. University of Wisconsin Medical Alumni Meeting, May 1999. “A Multidisciplinary Approach to Cerebrovascular Disease” Dempsey R. Wisconsin State Neurosurgical Society, June 1999. “Head Injury Management and Diagnosis” Dempsey R. St. Clare Hospital, Baraboo, WI February 2000. “Diagnosis of Acute Stroke” Dempsey R. Reedsburg Hospital, December, 2000. “Stroke: Diagnosis and Treatment” Dempsey R. University of Wisconsin Paramedic Seminar, January, 2001. “Stroke: Its Prevention and Early Treatment” Dempsey R. Wisconsin Educational Teleconference Network, March, 2001. “AVM Management” Dempsey R. Anesthesiology Grand Rounds, March, 2001. “Medical Mission Ecuador Specialized Medical Care to an Underserved Region” Dempsey R. Madison Rotary, July 2001. “Stroke is an Emergency”, Robert J. Dempsey, M.D. 33rd Annual Conference on Emergency Care, University of Wisconsin, August 2001.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 13 “The New Era of Aggressive Intervention for Stroke” Robert Dempsey, 4th Annual Professional Symposium, St. Vincent’s Hospital, Green Bay WI, September 2001. “Acute Stroke: 2001 Therapeutics Introduction”, Robert Dempsey Acute Stroke, Madison WI, November 2001. “Surgical Options for Acute Stroke” Robert Dempsey, Acute Stroke, Madison WI, November 2001. “Management of Acute Stroke” Dempsey R., Critical Care Symposium, Madison WI, November 2001. “Stroke: Acute Therapy and Prevention” Dempsey R., Annual Primary Care Conference, University of Wisconsin, Madison, WI, December 2001. “Nothing New Under the Sun: The EC-JC Bypass Revisited” Dempsey R., Neurosurgery Grand Rounds, January 2002. “Gene Therapy-Ischemia and Neurogenesis” Dempsey R., Neurosurgery Grand Rounds, March 2002. “Stroke: Its Prevention and Early Treatment” Dempsey R., Medical Grand Rounds, April 2002. “Stroke” Dempsey R., Madison Senior Center, May 2002. “Neurosurgery in Latin America” Dempsey R., Critical Care Nurses Conference, Madison, WI, May 2002. “New Concepts in the Diagnosis and Treatment of Stroke” Dempsey R., Updates in Medicine, Appleton, WI, May 2002. “Subarachnoid Hemorrhage”, Dempsey R., Neurology Grand Rounds, Madison, WI, October 2002. “Subarachnoid Hemorrhage”, Dempsey R., Neurology Grand Rounds, University of Wisconsin- Madison, October 2002. “Commitment to Excellence in a Challenging Medical World”, Dempsey R., Guest Speaker, Univerisity of Wisconsin AOA Awards, October 2002. “Noninvasive Diagnosis of Carotid Disease”, Dempsey R., Neurourgery Grand Rounds, December 2002. “Subarachnoid Hemorrhage Senitle Bleed and Symptomatic Aneurysms”, Dempsey R., University of Wisconsin Stroke Symposium, December 2002. “Subarachnoid Hemorrhage and Intracranial Aneurysms”, Dempsey R., Neuroscience Nursing, March 2003. "Neurogenesis after Stroke: Can the Brain Heal Itself?", Dempsey R., Veterinary School Seminar, October, 2003.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 14 "Cerebral Arterial Venous Malformation: A Scientific Approach to a Difficult Problem", Dempsey R, Medical College of Wisconsin, November 2003. "Carotid Plaque and Revascularization", Dempsey R., The Dynamics of Stroke Care Symposium, UW Hospital, January 2004. "Neurosurgical Humanitariasnism and Medicine in the Third World", Dempsey R, Neurosurgical Grand Rounds, April, 2004. "Stroke - Diagnosis and Treatment", Dempsey R, UW Madison Association of Retired Faculty, October 2004. "Professionalism in Medicine: Vital Responsibility or Lost Art?", Charles Lobeck Lecture, University of Wisconsin Medical School Medical Education Day Keynote Address, October 2004. "Central Nervous System Trauma", Grand Rounds, Freeport Memorial Hospital, Freeport, IL, December 2004. "Hemorrhagic Stroke", Dempsey R, 3rd Annual Conference on Stroke and Nursing Care, University of Wisconsin Hospital and Clinics, January 2005. "Stroke--Its Prevention and Early Treatment", Dempsey R, Divine Savior Healthcare, Portage, WI, May 2005. “Providing Sub-Specialty Medical Education in Developing Countries”, Dempsey R, Global health Symposium Inaugurating the Center for Global health at UW-Madison, Global Health and the Millennium Development Goals, Madison, WI, December 2005. “Science, Research and Clinical Neurosurgery: Lead or Get Out of the Way”, Dempsey R, Research Day Symposium, Department of Neurological Surgery, UW School of Medicine, September 2006. “Neurosurgery Societys and Boards – How do they Determine our Future”, Dempsey R, Department of Neurological Surgery Grand Rounds, UW School of Medicine, November 2006. “Hemorrhagic Stroke”, Dempsey R, Evolution in the Approach to Stroke in Wisconsin Conference, May 2007. National “Experimental Augmentation of Cerebral Blood Flow by Mannitol in Epidural Intracranial Masses” Dempsey R, Kindt G; The American Association for the Surgery of Trauma Annual Meeting, September, 1981. “Neurophysiology of the Pineal Gland” Dempsey R; 13th Annual Edgar A. Kahn Neurosurgical Meeting, September, 1981.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 15 “Pathologic Cerebral Vasodilation and Increased Intracranial Pressure in Experimental Hepatic Encephalopathy” Dempsey R, Kindt G; American College of Surgeons Annual Mtg., October, 1981. “Experimental Acute Hepatic Encephalopathy: The Relationship of Pathological Cerebral Vasodilation to Increased Intracranial Pressure” Robert J. Dempsey, Resident Award. Paper presented at the Central Neurosurgical Society Annual Meeting, March 1982. “Melatonin Secretion after Pinealectomy” Dempsey R, Bittman E, Hopkins J; American Association of Neurological Surgeons Annual Meeting, 1982. “Pineal Melatonin Mediates Photoperiodic Drive of Season Changes in Pulsatile LH Secretion in Sheep” Bittman E, Karsch F, Dempsey R; The Endocrine Society 64th Annual Meeting, San Francisco, California, June 16-18, 1982. “Diurnal Variation in Serum Melatonin Levels in Patients with Intrasellar and Third Ventricular Region Tumors” Dempsey RJ, Chandler WF; American Association of Neurological Surgeons 1983 Annual Meeting, April, 1983. “Beneficial Effects of Indomethacin on Ischemic Edema, Cerebral Perfusion, and Somatosensory Evoked Potential Following Experimental Stroke” Dempsey RJ, Roy M, Meyer K, Donaldson D, Young B; The Southern Neurosurgical Society, March, 1984. “The Application of Somatosensory Evoked Potentials to Experimental Cerebral Ischemia” Meyer KL, Dempsey RJ, Roy MW, Donaldson DL; The Southern Neurosurgical Society, March, 1984. “Indomethacin Reduces Ischemic Edema and Improves Somatosensory Evoked Potential in Experimental Middle Cerebral Artery Occlusion” Dempsey RJ, Roy MW, Meyer KL, Donaldson D; The American Association of Neurological Surgeons, April, 1984. “Adverse Effects of Diltiazem on the Pathophysiology of Middle Cerebral Artery Occlusion in Cats” Roy MW, Meyer KL, Dempsey RJ, Donaldson DL; The American Association of Neurological Surgeons, April, 1984. “Indomethacin-mediated Improvement in SSEP Following Middle Cerebral Artery Occlusion: Effects of Anesthesia” Meyer KL, Dempsey RJ, Donaldson DL, Roy MW; American College of Surgeons, October, 1984. “The Contribution of Ornithine Decarboxylase Activity to the Pathophysiology of Cerebral Ischemia” Dempsey RJ, Roy MW, Meyer KL, Olson JW; The American Academy of Neurological Surgery, October, 1984. “The Metabolic and Nutritional Sequelae of Non-Steroid-Treated Head-Injured Patients” Ott L, Young B, Norton J, Rapp R, Tibbs P, Dempsey R; American Society for Parenteral and Enteral Nutrition, January, 1985. “Arachidonate Metabolites in Cerebral Ischemia: A Delicate Balance” Dempsey R, Roy M, Cowen D, Edwards Maley M; Southern Neurosurgical Society, March, 1985.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 16 “The Cellular Immune Depression of Non-Steroid-Treated Severely Head-Injured Patients” Young AB, Ott L, Thompson J, Tibbs P, Dempsey R, McClain C; The Southern Neurosurgical Society, March, 1985. “Polyamine Production in Transient Cerebral Ischemia with Reperfusion: Interaction with Arachidonic Acid Metabolites” Dempsey RJ, Roy M, Meyer K, Olson J; American Association of Neurological Surgeons, April, 1985. “Penumbra Specific Improvement Associated with Imidazole in Cats Subjected to Middle Cerebral Artery Occlusion” Roy M, Dempsey R, Donaldson D, Tibbs P, Young B; American Association of Neurological Surgeons, April, 1985. “Leukotriene and Edema after Transient Cerebral Ischemia” Dempsey RJ, Roy MW, Cowen DE, Maley ME; American College of Surgeons, October, 1985. “Metabolic Events in Cerebral Ischemia: New Outlooks on an Old Problem” Dempsey RJ; 17th Annual Edgar A. Kahn Society Meeting, November, 1985. “Magnetic Resonance Imaging of Experimental Stroke” Dempsey RJ, Carr WA, Cowen D, Smith SL, Roy MW, Young AB; Southern Neurosurgical Society, February, 1986. “Polyamine Inhibition Preserves Evoked Neuronal Activity after Experimental Transient Cerebral Ischemia” Dempsey RJ, Maley ME, Cowen D, Maley B, Young AB; American Association of Neurological Surgeons, April, 1986. “Serum Osmolality and Intracranial Pressures in Severe Head-Injured Patients Randomized to Receive Parenteral or Enteral Nutrition” Young B, Ott L, Twyman D, Tibbs P, Dempsey R; Congress of Neurological Surgeons, 1986. “Measurement of Somatosensory Evoked Potential in the Mongolian Gerbil: Effects of Ischemia and Temperature” Cowen DE, Combs DJ, Dempsey RJ; Society for Neuroscience, 1986. “Ischemic Cerebral Edema: A Possible Early Marker for Stroke Damage” Dempsey RJ, Cowen DE; 32nd Meeting of the Frederick A. Coller Surgical Society, 1986. “Does Nutritional Support Affect Outcome from Severe Head Injury: A Reexamination” Ott L, Young B, Twyman D, Norton J, Rapp R, Tibbs P, Haack D, Bivins B, Dempsey R; American Society for Parenteral and Enteral Nutrition, February, 1987. “Intolerance to Enteral Feeding in Brain-Injured Patients: Possible Mechanisms” Norton J, Ott L, Adams L, Dempsey R, Tibbs P, Rapp B, Young B; American Society for Parenteral and Enteral Nutrition, February, 1987. “Does Carotid Artery Stenosis Predict Cerebral Ischemic Risk?” Dempsey RJ, Young AB; Southern Neurosurgical Society, March, 1987. “Relationship Between Admission Hyperglycemia and Neurological Outcome of Severe Brain- Injured Patients” Young B, Ott L, Haack D, Dempsey R, Tibbs P; Southern Neurosurgical Society, March, 1987.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 17 “Lipoxygenase Dependent Aspects of Focal Ischemic Edema” Roy MW, Dempsey RJ, Cowen DE, Donaldson DL; American Association of Neurological Surgeons, April, 1987. “Surgery for Single Brain Metastases: A Prospective Randomized Trial” Patchell RA, Young AB, Tibbs PA, Walsh JW, Dempsey R, Maruyama Y, MacDonald J; American Academy of Neurology, April, 1987. “Gerbil Forebrain Ornithine Decarboxylase Activity and Cellular Localization Following Transient Cerebral Ischemia” Olson J, Maley B, Combs D, Maley M, Dempsey R; The Gordon Conference on Polyamines, July, 1987. “The Acute Phase Response of Head-Injured Patients” Young AB, Ott L, Beard D, Tibbs P, Dempsey R, McClain C; American College of Surgeons Clinical Congress, October, 1987. “CNS Trauma” Dempsey RJ, Ott L; American Society for Parenteral and Enteral Nutrition, Postgraduate Course, 1987. “The Immune Status of Head-Injured Patients as Evaluated by Monoclonal Antibodies” Young AB, Ott L, Rhodes J, McClain C, Dempsey R, Tibbs P, Schoonover K, Thompson J; Congress of Neurological Surgeons 37th Annual Meeting, October, 1987. “Ornithine Decarboxylase Activity and Brain Edema after Transient Cerebral Ischemia” Dempsey R, Combs D, Olson J, Maley M; Southern Neurosurgical Society, March, 1988. “Carotid Artery Atherosclerotic Plaque without Flow Reducing Stenosis — An Indicator of Overall Ischemic Risk” Dempsey RJ; American Association of Neurological Surgeons, April, 1988. “In Vivo High Energy Phosphate Flux During Transient Cerebral Ischemia Using Very High Magnetic Field 31P NMR” Dempsey RJ, Combs DJ, Donaldson D, Thomas G; Congress of Neurological Surgeons, September, 1988. “MRI Spectroscopy in the Investigation of Cerebral Ischemia” Dempsey RJ; 34th Clinical Meeting of the Frederick A. Coller Surgical Society, October, 1988. “The Use of NMR Investigation of High Energy Phosphate Bonds after Transient Cerebral Ischemia” Dempsey RJ; 20th Annual Edgar A. Kahn Neurosurgical Meeting, October, 1988. “Altered Gastric Emptying after Head Injury and Its Relation to Feeding Intolerance” Ott L, Phillips R, young B, McClain C, Dempsey R, Tibbs P, Ryo U; American Society for Parenteral and Enteral Nutrition, February, 1989. “The Effect of Zinc Supplementation on Zinc Status after Head Injury” Holt K, Young B, Ott L, Williams F, Phillips R, Rapp R, Dempsey R, Tibbs P, McClain C; Association of Academic Physiatrists, March, 1989. “Protection from the Effects of Transient Ischemia by the Glutamate Receptor Antagonist MK-801 and Related Compounds” Dempsey RJ, Combs DJ, Carney JM, Maley M, Wu Z; American Association of Neurological Surgeons, April, 1989.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 18 “Very Rapid Dynamic MR Imaging with GdDTPA of Cerebral Vascular System” Dempsey R, Dean B, Lee C, Howard R, Dineen T, Pettigrew L, Runge V; Southern Neurosurgical Soc., April, 1990. “Induction of the Proto-Oncogene, c-fos, in Reperfused Brain after Transient Ischemia: Relationship to Brain Edema Development” Dempsey R, Kindy M, Combs D, Carney J; American Association of Neurological Surgeons, May, 1990. “Dynamic GdDTPA Brain Imaging and Cerebral Blood Flow with Turbo-Flash Imaging” Dean B, Lee C, Runge V, Howard R, Dempsey R, Pettigrew L; American Society of Neuroradiology, 1990. “Dynamic Turbo-Flash Imaging of the Normal Cerebral Vasculature with an Intravenous GdDTPA Bolus” Lee C, Dean B, Runge V, Howard R, Dempsey R, Pettigrew L; American Society of Neuroradiology, 1990. “Restenosis of Carotid Arteries after Carotid Endarterectomy” Dempsey R, Moore R, Cordero S; American Association of Neurological Surgeons, April, 1991. “The Expression of Oncogenes in the Early Response of the Brain to Transient Ischemia” Dempsey R, Kindy M, Combs D; Research Society of Neurological Surgeons, May, 1991. “An MRI Spectroscopic Study of Delayed Hyperglycemia in Focal Cerebral Ischemia” Dempsey R, Combs D, Donaldson D; Neurosurgery Society of America, May, 1991. “Carotid Endarterectomy for Non-Invasive Imaging” Dempsey R; American Association of Neurological Surgeons, April, 1992. “Cerebral Infarction and the Ages of Man” and “Evaluation and Early Treatment of Cerebrovascular Disease” Dempsey R; 4th Annual National Conference, Special Care Issues in Dentistry, American Dental Association, April, 1992. “Ornithine Decarboxylase Expression in Brain: The Molecular Biology of Brain Edema” Dempsey R, Kindy M, Carney J; Southern Neurosurgical Society, April, 1992. “Toward Noninvasive Biochemical Analysis of Carotid Artery Plaque Lipids” Dempsey R, Cassis L, Lodder R; Congress of Neurological Surgeons, November, 1992. “Zinc Supplementation Improves Recovery Rate and Visceral Protein Levels in Patients with Severe Closed Head Injury” Young B, Ott L, Moles K, Dempsey R, Tibbs P, Kryscio R, McClain C; Congress of Neurological Surgeons, November, 1992. “Lessons from Carotid Endarterectomy: Early Detection of the Patient at Risk of Progressive Plaque Development” Dempsey R, Kindy M, Lodder R; Neurosurgical Society of America, March, 1993. "Near-Infrared Imaging in Stroke Research", invited paper #674 at the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Atlanta, GA), March 1993. “Carotid Endarterectomy: Making the Diagnosis Noninvasively” Dempsey R; American Association of Neurological Surgeons, April, 1993.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 19 “Carotid Endarterectomy and Surgical Treatment of Intracranial Aneurysms” Dempsey R; National Stroke Association, 93 Symposium, October, 1993. “Surgery of the Cervical Carotid Artery” Smith R, Dempsey R, et al.; Congress of Neurological Surgeons 43rd Annual Meeting, October, 1993. “Lipoprotein Oxidation Analysis, Special Course III. Critical Care and Intensive Monitoring” Dempsey R; Congress of Neurological Surgeons 43rd Annual Meeting, October, 1993. “Accumulation of Free Fatty Acids and Edema Formation in Focal Ischemia” Prasad MR, Ramaiah C, Donaldson D, Hu Y, Dempsey R; Society for Neuroscience Annual Meeting, November, 1993. “Neurologic Functions after Lateral Cortical-Impact Brain Injury in Rats” Prasad MR, Ramaiah C, Kraemer P, Scheff S, Baldwin SA, Dempsey R; 11th Annual Meeting Neurotrauma Society, November, 1993. “Regional Levels of Lactate and Norepinephrine after Cortical-Impact Brain Injury in Rats” Prasad MR, Ramaiah C, Dempsey R, Yurek D; 11th Annual Meeting Neurotrauma Society, November, 1993. "Near-IR Spectrometry of Human Carotid Plaques", invited presentation at the 32nd Annual Eastern Analytical Symposium (Somerset, NJ), November 1993. "Near-IR Spectrometric Imaging in Symptomatic Carotid Occlusive Disease", invited presentation at the Pittlsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Chicago, IL), March 1994. “Leukotriene Inhibition Decreases Brain Edema after Transient Cerebral Ischemia” Dempsey RJ, Maley M, Donaldson D, Prasad R, Hu Y; American Association of Neurological Surgeons Annual Meeting, April, 1994. “Intra-operative Cerebral Monitoring and Protection” Dempsey R; American Association of Neurological Surgeons Annual Meeting, April, 1994. “New Aspects in Stroke Research” Dempsey R; Southern Surgeons Club Annual Mtg., April, 1994. “Carotid Surgery/Transcranial Doppler/Carotid Doppler” Dempsey R; Congress of Neurological Surgeons, October, 1994. “Leukotriene Inhibition Limits Delayed Ischemic Brain Damage” Dempsey R, Hu Y, Prasad R, Kindy M; Congress of Neurological Surgeons, October, 1994. “Non-invasive Diagnosis of Cerebrovascular Disease” Dempsey R; Congress of Neurological Surgeons, October, 1994. “Pneumatic Impactor Model of Head Injury Simulates Metabolic Aspects of Human Head Injury” Young B, McClain C, Kindy M, Dempsey R, Blouin R, Gillespie M, Scheff S; Congress of Neurological Surgeons, October, 1994.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 20 "Lipoprotein Oxidation and Symptomatic Carotid Artery Atherosclerosis", Dempsey R, David D, Lodder R and Moore R; 1994 Annual Meeting of the Neurological Society of America (Blaine, WA), 1994. “Surgical Research: From the Laboratory to the Patient” Dempsey R; University of Wisconsin Department of Neurosurgery Lecture, March, 1995. “Practical Clinic Carotid Endarterectomy. Making the Diagnosis Noninvasively” Dempsey R; American Association of Neurological Surgeons, April, 1995. “Antisense Oligonucleotide Treatment Against Cerebral Ischemic Injury” Baskaya M, Rao A, Prasad M, Kindy M, Dempsey RJ; American Association of Neurological Surgeons, April, 1995. “Insulin-like growth factor-I and Neurologic Outcome” Hatton J, Rapp, Kudsk, Brown, Bukar, Dempsey, McClain, Young; Southern Neurosurgical Society, April, 1995. Special Lecture: “Cerebral Protection During Cerebrovascular Surgery — Lessons form the Laboratory” Dempsey R; Southern Neurosurgical Society, April, 1995. “Effect of Ifenprodil on Infarct Size, Blood-Brain Barrier Breakdown and Edema Formation after Focal Cerebral Ischemia” Baskaya M, Rao A, Donaldson D, Prasad M, Dempsey R; Society for Neuroscience, November, 1995. “ODC Activity and Edema Formation In Cerebral Ischemia of Gerbils” Rao A, Baskaya M, Maley M, Prasad M, Dempsey R; Society for Neuroscience, November, 1995. “Effect of α-Difluoromethylornithine Treatment on Ornithine Decarboxylase Activity and Brain Edema after Traumatic Brain Injury” Dempsey R, Baskaya M, Rao A, Prasad M; The American Academy of Neurological Surgery, November 1-5, 1995. “Developing a Community Based Program” Dempsey R; Special Course Congress of Neurological Surgeons, October, 1995. “Carotid Surgery” Dempsey R; Congress of Neurological Surgeons, October, 1995. “Building a Carotid Practice: The Role of Special Studies” Dempsey R; Congress of Neurological Surgeons, October, 1995. “An Inverse Correlation Between Dosing Time of Dismutec and Plasma IL-8 Concentrations in Traumatic Brain Injury” Young B, Hatton J, McClain C, Salatto A, Dempsey R; Congress of Neurological Surgeons, October, 1995. “Diagnostic Evaluation” Dempsey R; Carotid Endarterectomy AANS/CNS Joint Section on Cerebrovascular Surgery, September, 1995. “Carotid Embolic Stroke: It’s Pathophysiology and Potential for Prevention” Dempsey R; University of Chicago Visiting Professor, February, 1996, Chicago, IL. “Cerebral Protection” Dempsey R; University of Chicago Visiting Professor, February, 1996.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 21 “Quantification of Regional Blood-Brain Barrier Changes after Cortical Impact Brain Injury” Baskaya M, Rao AM, Puckett L, Prasad R, Dempsey R; American Association of Neurological Surgeons, April, 1996, Minneapolis, MN. “Carotid Endarterectomy Diagnosis” Dempsey R; American Association of Neurological Surgeons, April, 1996, Minneapolis, MN. “Carotid Surgery: Practical Course” Dempsey R; Congress of Neurological Surgery, September, 1996, Montreal, Canada. “Atherosclerosis: Its Pathophysiology and Application to Surgical Practice” Dempsey R; American College of Surgeons, October, 1996, San Diego, CA. “Effect of phospholipase A2 (PLA2) inhibitor, CDP-choline on regional activities of ornithine decarboxylase (ODC) and blood-brain barrier (BBB) breakdown after transient ischemia” Rao AM, Baskaya MK, Dogan A, Dempsey RJ; Society for Neuroscience, November, 1996, Washington, D.C. “The Time Course of Regional Blood-Brain Barrier Breakdown and Correlation with Brain Edema Formation After Experimental Brain Injury” Baskaya M, Dogan A, Adibhatla R, Dempsey R. American Association of Neurological Surgeons, April 1997, Denver. “Characterization of Somatosensorial Evoked Potentials After Controlled Cortical Impact Brain Injury” Dogan A, Baskaya M, Donaldson D, Adibhatla R, Dempsey R. American Association of Neurological Surgeons, April 1997, Denver. “Imaging for Extracranial Vascular Disease” Seminar. American Association of Neurological Surgeons, April 1997, Denver. “Carotid Endarterectomy” Review Course. American Association of Neurological Surgeons, April 1997, Denver. “IGF-IGH Achieves Positive Nitrogen Balance After Acute Traumatic Brain Injury” Young B, Hatton J, Dempsey R, McClain C, Rapp R. Congress of Neurological Surgeons, October 1997, New Orleans. “The Role of the Polyamine Interconversion Pathway on Brain Edema Formation After Traumatic Brain Injury” Dogan A, Baskaya M, Rao A, Rao VLR, Dempsey R. Congress of Neurological Surgeons, October 1997, New Orleans. “Practical Carotid Surgery Course: The Value of Ultrasound” Dempsey R. Congress of Neurological Surgeons, October 1997, New Orleans. “Neuroprotective Effects of CDP-Choline on Brain Edema and Blood-Brain Barrier Breakdown After Traumatic Brain Injury” Baskaya M, Rao A, Dogan A, Rao VLR, Salamat S, Dempsey R. Congress of Neurological Surgeons, October 1997, New Orleans. “Carotid Endarterectomy: New Advances; Operating Without Angiogram” Dempsey R. Congress of Neurological Surgeons, October 1997, New Orleans.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 22 “Traumatic Brain Injury Down-Regulates Glial Glutamate Transporters GLT-1 and GLAST. Rao VLR, Baskaya M, Dogan A, Rao A, Rothstein J, Dempsey R. Soc. for Neuroscience, October 1997. “Fluorometric Assay of Nitrite and Nitrate in Brain Tissue After Head Injury and Ischemia” Rao A, Hatcher J, Baskaya M, Dogan A, Rao VLR, Dempsey R. Society for Neuroscience, October 1997. “Application of Intraluminal Suture Occlusion of Middle Cerebral Artery in Gerbils to Obtain Consistent Infarction” Baskaya M, Dogan A, Rao A, Rao VLR, Rastl J, Dempsey R. Society for Neuroscience, October 1997. “Decision-Making and Management of Unruptured Aneurysms” Dempsey R. The Joint Section of Cerebrovascular Surgery of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, February 1998. “Critical Care of Cerebrovascular Patients” Dempsey R. The Joint Section of Cerebrovascular Surgery of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, February 1998. “Decreased Cerebral Glial Glutamate Transporter GLT-1 Protein Levels Following Transient Middle Cerebral Artery Occlusion in SHR Rats” Rao VLR, Dogan A, Rothstein JD, Dempsey RJ. American Society of Neurochemistry, March 1998. “The Role of the Polyamine Interconverstion Pathway on Reperfusion Injury in Rats After Transient Focal Cerebral Ischemia” Dogan A, Rao A, Baskaya M, Vemuganti R, Temiz C, Dempsey R. American Association of Neurological Surgeons, Philadelphia, April 1998. “Transient Focal Cerebral Ischemia Down-Regulates the Expression of the Glial Glutamate Transporter GLT-1 Protein Expression in Rat Brain” Dempsey R, Rao V, Dogan A. Neurosurgical Society of America, Quebec City, May 1998. “Satellite Hospitals as a Source of Funding.” Nurturing Young Faculty. Dempsey R. The Society of Neurological Surgeons, St. Louis, May 1998. “Up-regulation of Na+-K+-2Cl- Cotransporter Activity in Glial Cells Under High [K+] a Ca++ Dependent Process” Su G, Dempsey R, Sun D. 1998 Gordon Research Conference, “Membrane Transporters: Physiological & Pathological Implications,” July 1998. “Carotid Artery Surgery: Ultrasound & TCD” Dempsey R. Congress of Neurological Surgeons, October 1998. “Protective Effects of Ifenprodil, NMDA Receptor Antagonist at Polyamine Site, on Brain Edema and Blood-Brain Barrier Breakdown After Experimental Traumatic Brain Injury” Dogan A, Baskaya M, Dempsey R. Congress of Neurological Surgeons, October 1998. “Simultaneous Assay of Ornithine Decarboxylase (ODC) and Polyamines After Central Nervous System (CNS) Injury” Hatcher J, Rao A, Baskaya M, Dempsey R. Soc. of Neuroscience, Nov. 1998.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 23 “Accumulation of Arachidonic Acid and Leukotriene C4 Causes Edema Formation After Transient Cerebral Ischemia” Rao A, Hatcher J, Dogan A, Dempsey R. Society of Neuroscience, Nov. 1998. “Neuronal Nitric Oxide Synthase Expression is Upregulated Following Traumatic Injury in Rat Brain” Rao V, Dogan A, Dempsey R. Society of Neuroscience, November 1998. “Noninvasive Diagnosis of Unruptured Aneurysms” Dempsey RJ. The Joint Section of Cerebrovascular Surgery of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, February 1999. “Glial Glutamate Transporter GLT-1 Knockout Exacerbates Ischemic Neuronal Damage” Dempsey RJ, Rao V, Dogan A, Todd K. Neurosurgical Society of America, March 1999. “Carotid Endarterectomy and Stents: An Interactive Video Clinic” Dempsey R. American Association of Neurological Surgeons, April 1999. “The NIH and the Neurosurgeon” Dempsey R. The Society of Neurological Surgery, May 1999. “New Chairman Responsibilities” Dempsey R. Neurosurgery Chairman’s Conference, July 1999. “Update on the Asymptomatic Carotid Atherosclerosis Study” Dempsey R. The American College of Surgeons, October 1999. “Surgery of the Carotid Artery: Indications and Techniques” Dempsey R. Congress of Neurological Surgeons, October 1999. “Ischemic Severity and Neuroprotection by CDP-choline” Hatcher J, Dempsey R, Rao A. Society of Neuroscience, November 1999. “Blockade of mGluR alternates ischemic-induced arachidonic acid release and neuronal death” Rao A, Hatcher J, Dempsey R. Society of Neuroscience, November 1999. “Controlled cortical impact to rat brain up-regulates peripheral-type benzodiazepine receptor expression in the thalamus” Dempsey R, Rao V, Dogan A, Bowen K. American Academy of Neurological Surgery, November 1999. “Attenuation of Brain Edema Formation and Ischemic Injury Volume by CGP40116 after Ischemic Reperfusion Injury Dogan A, Eras M, Dempsey R. Congress of Neurological Surgeons, November 1999. “Increased Peripheral-type Benzodiazepine Receptor (PTBR) Expression in Hippocampal CA1 Region Following Transient Forebrain Ischemica Rao VL, Bowen KK, Rao AM, Dempsey RJ. American Society for Neurochemistry, March, 2000. “Symposium: Cerebral Ischemia,” Moderator Dempsey R, Tomsick T. Joint Meeting of the AANS/CNS Section on Cerebrovascular Surgery and American Society of International and Therapeutic Neuroradiology, February, 2000.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 24 "Protective effects of CGP39551 on Brain Edema and Ischemic Injury Volume Induced by Ischemia/Reperfusion," Dogan A, Eras M, Unlu A, Dempsey R, American Association of Neurological Surgery, April, 2000. "Review of the Council of Medical Specialty Societies" Society of Neurological Surgeons, May 2000. “Radiologic Adjuncts to the Surgical Removal of AV Malformations” Dempsey, R. Neurological Society of America, June 2000. “Treatment of Carotid Disease: Making the Diagnosis” Dempsey, R. Congress of Neurological Surgery, September, 2000. “Practical Workshop on Duplex Doppler and TCD” Dempsey, R. Congress of Neurological Surgery, September 2000. “Adjunctive Use of Preoperative Functional Magnetic Resonance Imaging for Cerebral AV Malformation Surgery” Lapsiwala S, Nguyen P, Haughton V, Dempsey R. Congress of Neurological Surgery, September 2000. “International Program: Extreme Neurosurgery: Operating in a Hostile Environment” Dempsey R. Congress of Neurological Surgery, September 2000. “Grants: What Reviewers Look For” Dempsey, R. Congress of Neurological Surgery, September 2000. “Ornithine Decarboxylase and Normal Adaptive Responses to Transient Cerebral Ischemia” Dempsey, R. American Academy of Neurological Surgery, October 2000. New Concepts in the Diagnosis and Treatment of Arteriovenous Malformations: 21st Century Medicine in a 15th Century World” Dempsey R. University of Chicago Neurological Surgery Lecture, October 2000. “Ornithine decarboxylase activity following transient focal cerebral ischemia and reperfusion in rat” Golla N, Sailor K, Dogan A, Dempsey R. Society for Neuroscience, November 2000. “Career Tracks in Academic Neurosurgery” Dempsey R. Review and Update in Neurobiology for Neurosurgeons – Woodshole, MA, October 2000. “The Clinical Laboratory: AV Malformations from the OR to the Lab and Back Again” Dempsey R. Academic Day: Northwestern University Medical School, January 2001. “AVMs: A Clinical Protocal Based on Labatory Research” Dempsey R. Visiting Professor, Henery Ford Medical Center, March, 2001. “Molecular Biology in Cerebral Ischemia and Vasospasm” Dempsey R, Society of Neurological Surgery, Cleveland, May 2001. “Report on Council of Medical Specialty Societies” Dempsey R, Society of Neurological Surgery, May 2001.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 25 “Transcriptional Profiling of Ischemia Rat Brain Using Gene Chips” Dempsey R, Neurological Society of America, June 2001. “Treatment of Carotid Disease – Diagnostic Evaluation of Carotid Disease”, R Dempsey, Congress of Neurological Surgeons, October 2001. “Grants: What Reviewers Look For” Dempsey R, Congress of Neurological Surgoens, October 2001. “Contemporary Issues in the Management of Stroke” Dempsey R., Congress of Neurological Surgeons, October 2001. “Polyamine Interconversion Pathway in Transient Focal Cerebral Ischemia” Dempsey R, Rao A, Hatcher J, Golla N, Sailor K, Congress of Neurological Surgeons, October 2001. “Molecular Biology and Gene Therapy in Cerebrovascular Disease” Dempsey R, University of Illinois – College of Medicine, October 2001. Surgical Management of Arteriovenous Malformations Based on the Application of Investigative Results” Dempsey R, University of Illinois – College of Medicine, Grand Rounds, October 2001. “Does Citicoline Neuroprotection Go Beyond Phosphatidycholine (pc) Synthesis After Cerebral Ischemia? Adibhatla R, Hatcher J, Dempsey R, Society for Neuroscience, November 2001. “Gene Expression Analysis After Acute Spinal Cord Injury in Rat” Vemuganti R, Song G, Cechvala C, Resnick D, Dempsey R, Society for Neuroscience, November 2001. “The Foundation for International Education in Neurological Surgery: History and Goals for the Future”, R Dempsey, The American Academy of Neurolgical Surgery, November 2001. “Glial Cell Line Derived Neurotrophic Factor Protects Hippocampal Neurons After Traumatic Brain Injury in Rats”, BT Kim, VL Rao, KA Sailor, K Bowen, RJ Dempsey, The American Academy of Neurological Surgery, November 2001. “Activation of Na-K-C2 Cotransporter During Focal Cerebral Ischemia”, Yan Y, Dempsey R, Sun D, Society for Neuroscience, November 2001. “Cerebral Arteries Venous Malformations: Applying Laboratory Investigations to Clinical Treatment Protocol”, Dempsey R., Visiting Professor, Standford University, December 2001. “Can the Brain Heal Itself? Neurogenesis is Cerebral Ischemia”, Dempsey R., University of Michigan, Crosby Laboratory Presentation, March 2002. “Treatment of Complex Cerebrovascular Disorders from the Laboratory to Operating Room”, Dempsey R., Visiting Professor, University of Michigan, March 2002. “Glial Cell Line-Derived Neurotrophic Factor Protects Hippocampal Neurons after Traumatic Brain Injury in Rats”, Kim B., Dempsey R., American Association of Neurological Surgeons, April 2002.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 26 “Novel Moderators of Ischemic Preconditioning Induced Neuroprotection”, Dhodda V., Sailor K., Dempsey R., Vemuganti R., American Society for Neurochemistry Annual Meeting, June 2002. “The Scientific Basis of Treatment Cerebral AVM”, Dempsey R., Visiting Professor, Rush Medical School, September 2002. “Inclusion of a Compact Neurosurgical Curriculum Improves Third-year Medical Student Clinical Performance in the Diagnosis and Management of Lumbar Radiculopathy”, Resnick D., Ramirez L., Dempsey R., Badie B., Garell P., Iskandar B., Trost G., Congress of Neurological Surgeons, September 2002. “Glial Cell-line Derived Neurotrophic Factor Treatment Increases Remote Neuronal Proliferation after a Focal Stroke”, Dempsey R., Bowen K., Sailor K., Vemuganti R., The American Academy of Neurological Surgery, October 2002. “IGF Infusion Increases Ischemia-induced Cell Proliferation in Adult Rat Dentate Gyrus”, Sailor K., Vemuganti R., Bowen K., Dempsey R., Society for Neuroscience’s 32nd Annual Meeting, November 2002. “Novel Mediators of Ischemic Preconditioning Induced Neuroprotection”, Dhodda V., Sailor K., Dempsey R., Rao V., Society for Neuroscience’s 32nd Annual Meeting, November 2002. “Suppressor of Cytokine Signaling-3 (SOCS-3) is a Neuroprotective Gene Upregulated after Focal Ischemia”, Rao V., Bowen K., Dhodda V., Dempsey R., Society for Neuroscience’s 32nd Annual Meeting, November 2002. “IGF-1 Infusion Increases Ischemia-induced Cell Proliferation in Adult Rat Dentate Gyrus”, Society for Neuroscience’s 32nd Annual Meeting, November 2002. “Research and Update in Neuroscience for Neurosurgeons”, Dempsey R., Co-Director, October 2002. “Neurosurgery Research Philosophy and Scientific Writing: How to prepare a grant and a research paper”, Dempsey R., Research Update in Neuroscience for Neurosurgeon’s, Woodshole, MA, November 2002. “Dentate Gyrus Progenitor Cell Proliferation is Associated with IGF-1 Expressing Astrocytes after Stroke in Adult Rats”, Sailor K., Vemuganti R., Dempsey R., Society for Neuroscience, 2003. “A New Surgical Approach to Upper Cervical Region in Rats – Description of the Selective Anterior Spinal Argery Occlusion”, Tureyen K., Resnick D., Dempsey R., Hariharan N., Society for Neuroscience 2003. “Management Options in Occlusive Cervical Carotid Disease”, Dempsey R., Joint Section on Cerebrovascular Surgery Annual Meeting, Phoenix, Arizona, February 2003. “Diffusion Tensor Imaging of White Matter Tracts in Patients with Cerebral Vascular Malformations”, Dempsey R., Moftakhar R., Witwer B., Hasan K., Haughton V., Field A.,
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 27 Artanakis K., Noyes J., Moritz C., Meyerand E., Rowley H., Alexander A., Joint Section on Cerebrovascular Surgery Annual Meeting, Phoenix, Arizona, February 2003. “Report on Council of Medical Specialty Societies and Review of Neurobiology for Neurosurgeons”, Dempsey R., Society of Neurological Surgeons Annual Meeting, May 2003. "Predicting Carotid Artery Plaque Symptoms", Dempsey R, Vemuganti R, Dhodda V, Varghese T, Sailor K, Medow J, Neurosurgical Society of America, June 2003. "Use of MRI Scans in Neurosurgery", Dempsey R, Visiting Professor, Loyola University, Department of Neurological Surgery, July 2003. "Cerebral Arteriovenous Malformations: Applying Research to a Clinical Problem", Dempsey R, Visiting Professor, Loyola University, Department of Neurological Surgery, July 2003. "Pathophysiology of Carotid Disease", Dempsey R, Visiting Professor, Loyola University, Department of Neurological Surgery, July 2003. "What Makes a Carotid Atherosclerotic Plaque Symptomatic" Micro Array Analysis of Gene Expression", Dempsey R, Vemuganti R, Dhodda V, Varghese T, Salamat S, The American Academy of Neurological Surgery, October 2003. "Operative Colloquiumn: Masters of Neurological Surgery: FIENS, Neurosurgical Service and Equador", Dempsey R, Congress of Neurological Surgeons, October 2003. "The Research Idea: How to Write a Research Grant", Dempsey R, Review and Update in Neurobiology for Neurosurgeons, Woods Hole, MA, November 2003. "Dentate Gyrus Progenitor Cell Proliferation is Associated with IGF-1 Expressing Astrocytes after Stroke in Adult Rats", Sailor K, Vemuganti R, Dempsey R, Society of Neuroscience Annual Meeting, November 2003. "A New Surgical Approach to Upper Ventral Cervical Spinal Cord in Rats and Description of Selective Anterior Spinal Artery Occlusion", Tureyen K, Resnick D, Nithya H, Dempsey R, Society of Neuroscience Annual Meeting, November 2003. "Polyamine Response to CNS Injury: for Better or for Worse?", Hatcher J, Dempsey R, Adibhatla R, Society of Neuroscience Annual Meeting, November 2003. "Citocoliine Affects CTP: Phosphocholine Cytidylyltransferase and Lyso-Phosphatidylcholine after Transient Brain Ischemia", Adibhatla R, Hatcher J, Dempsey R, Society of Neuroscience Annual Meeting, November 2003. "Ischemic Preconditioning Induces Heat Shock Protein Gene Expression in Adult Rat Brain", Dhodda V, Sialor K, Dempsey R, Vemuganti R, Society of Neuroscience Annual Meeting, November 2003. "Prevention of Inflammation is a Mechianism of Preconditioning-Induced Neuroprotection Against Stroke", Vemuganti R, Dhodda V, Bowen K, Dempsey R, Society of Neuroscience Annual Meeting, November 2003.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 28 "Science, Stroke Centers and Research: Clinical Neurosurgery Must Lead the Charge or Follow the Dinosaurs", Dempsey R, 2004 Annual Meeting, Interurban Neurosurgical Society, March 2004. "The Impact of ACCME & OIG Rules on Commercial Support of Academic Medicine", Dempsey R, Council of Medical Specialty Societies, Chicago, IL, March 2004. "Report on the Council of Medical Specialities Society to the Society of Neurological Surgeons", Dempsey R, Society of Neurological Surgeons Annual Meeting, New Orleans, LA, May 2004. "The Review Update in Neurobiology for Neurosurgeons", Dempsey R, Society of Neurological Surgeons Annual Meeting, New Orleans, LA, May 2004. "The Use of Real Time Physiologic Data to Guide Intraoperative Decision-Making in AVM Resection", Dempsey R, Neurosurgical Society of America, Santa Fe, NM, June 2004. "Intraoperative Doppler to Measure Cerebrovascular Resistance as a Guide to Complete Resection of Arteriovenous Malformations", Dempsey R, Moftakhar R and Pozniak M, American Association of Neurological Surgeons Annual Meeting, May 2004. "Humanitarian Medicine: FIENS and Ecuador", Dempsey R, American Association of Neurological Surgeons Annual Meeting, May 2004. "Transient Focal Cerebral Ischemia Induces Neurogenesis in Adult Mouse Dentate Gyrus", Tureyen K, Vemuganti R, Sailor K, Bowen K and Dempsey R, American Association of Neurological Surgeons Annual Meeting, May 2004. "Carotid Atherosclerosis: Past, Present and Future based on Research Considerations", Dempsey R, 16th Annual Physical Medicine and Rehabilitation Research Day, University of Kentucky, June 2004. "Using Research to Direct the Solution to a Clinical Problem: Arteriovenous Malformations", Dempsey R, Combined Neurosurgery and Neurology Grand Rounds, Visiting Professor, University of Kentucky, June 2004. "Carotid Atherosclerosis & Stroke: The Neurosurgical Past, Present and Future", Dempsey R, Visiting Professor, Oregon Health Sciences University, September 2004. "Intraoperative Doppler ultrasound as a guide to surgical removal of cerebral arteriovenous malformation", Pozniak, MA, Dempsey RJ, Mitchell CC, American Society of Neuroradiology 2004. June 7-11, 2004, Seattle, WA. "Internationa l Opportunities in Neurosurgery", Dempsey R, Congress of Neuroloigcal Surgeons, San Francisco, CA October 2004. "Research and Clinical Neurosurgery", Dempsey R, Review and Update in Neurobiology for Neurosurgeons, Woods Hole, MA, November 2004. "Does CDP-Choline Partly Counteract TNF-α Mediated Events after Stroke?", Adibhatla RM, Hatcher JF, Tureyen K, Tsao FH, Dempsey RJ, Society for Neuroscience Meeting, November 2004.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 29 "Beneficial Effects of Exogenous Spermine in Transient Focal Cerebral Ischemia", Hatcher JF, Adibhatla RM, Tureyen K, Dempsey RJ, Society for Neuroscience Meeting, November 2004. "EGF and FGF-2 infusion increases post-ischemic progenitor cell proliferation in adult rat brain", Tureyen K, Dempsey RJ, Bowen KK, Sailor KA, Iskandar BJ, Vemuganti R, Society for Neuroscience Meeting, November 2004. "Impaired hippocampal neural progenitor cell proliferation in adult interleukin-6 knockout mice", Bowen KK, Tureyen K, Sailor KA, Dempsey RJ, Vemuganti V, Society for Neuroscience Meeting, November 2004. "Proliferation and gene expression profiles of neural stem cell cultures (neurospheres) from the DG and SVZ of adult rat brain", Kalluri H, Sailor KA, Vemuganti R, Dempsey RJ, Society for Neuroscience Meeting, November 2004. "Neurosurgical and Endovascular Volunteerism in Developing Countries", Dempsey R, Young P, Jeck D, Chicoine M, Gunel M, 8th Joint Annual Meeting of the AANS/CNS Cerebrovascular Section and the American Society for Interventional and Therapeutic Neuroradiology, February 2005, New Orleans, LA. "Stem Cells and Nanobiology", Dempsey R, Moderator, Interurban Neurosurgical Society Annual Meeting, Chicago, IL, March 2005. "Carotid Atherosclerosis and the Neurosurgeon: Past, Present and Future", University of Illinois- Chicago, Visiting Professor, April 2005. "European and United States Residency Training", Dempsey R, American Academy of Neurological Surgeons Meeting, April 2005. "Carotid Atherosclerosis and the Neurosurgeon: Past, Present and Future", Dempsey R, Sally Harrington Goldwater Visiting Professor lecture, Barrow Neurological Institute, May 2005. "Council on Medical Specialty Societies and Review and Update on Neurobiology for Neurosurgery", Dempsey R, Society of Neurological Surgeons, May 2005. “Cytokines, lipid metabolism, and CDP-Choline in Stroke”, Adibhatla RM, Hatcher J, Tureyen K, Tsao, F, Dempsey R, 36th Annual American Society of Neurochemistry, Madison, WI June 2005. "Science - Research and Neurosurgery - Lead or Get out of the Way", Dempsey R, Hoff Scientific Symposium, Ann Arbor, MI, July 2005. “Cytokines, lipid metabolism, and CDP-Choline in Stroke”, Adibhatla RM, Hatcher J, Tureyen K, Tsao, F, Dempsey R, Gordon Conference on Molecular and Cellular Biology of Lipids, Waterville Valley Resort, NH, July 2005. "Carotid Atherosclerosis: Why do some Plaques Embolize?", Dempsey R, Tureyen K, Salamat S, Vemuganti R, American Academy of Neurolgoical Surgery, Half Moon Bay, CA, September 2005.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 30 "Temporary Clipping and Ischemic Anuerysm Surgery", Dempsey R, Congress of Neurological Surgeons Annual Meeting, Boston, MA, October 2005. “Putting Scientific Thought Together: What a Reviewer looks for in a great Manuscript” Dempsey R, presented as Co-Director – Research update in Neuroscience for Neurosurgeons, Woods Hole, Massachusetts, October 23-25, 2005 Yan Y, Sailor K, Vemuganti R, Dempsey R: Increased IGF-1 Expression Plays a Role in Stroke- Induced Neurogenesis, Society for Neuroscience Annual Meeting, November 2005. Kalluri H, Vemuganti R, Dempsey R: Effect of IGF-1 on the Adult Neuroprogenitor Cells Isolated from Rat Brain, Society for Neuroscience Annaul Meeting, November 2005. "Caroid Atherosclerosis: A Potential Neurosurgical Frontier", Dempsey R, Cornell University, New York, NY, November 2005. "Carotid Atherosclerosis: Present and Future Treatment based on increased understanding of the Disease", Dempsey R, Rush University, Chicago, IL, December 2005. “Providing Sub-specialty Medical Education in Developing Countries”, Dempsey R, Global Health Symposium, December 7, 2005 “Treatment of Complex Cerebrovascular Disorders”, Dempsey R, Albany Medical School, March 2006. “Vascular Biology of Carotid Atherosclerosis”, Dempsey R, Albany Medical School, March 2006. “Vascular Biology and Atherosclerosis: How are Vessels Determine our Future”, Dempsey R, Donaghy Award Presentation, American Association of Neurolgoical Surgeons Meeting, San Francisco, CA, April 2006. “Atherosclerosis and Stroke: A Potential New Frontier for Neurosurgery, Dempsey R, Visiting Professor, Brigham and Women’s Hospital, Harvard Medical School, May 2006. “Carotid Atheroslcerosis: Lessons from the Past-Window to the Future, Dempsey R, Visiting Professor, Ohio State University, Department of Neurological Surgery, May 2006. “Models of Compensation in Academic Neurosurgery: Salary with Bonus Model”, Dempsey R, Soceity of Neurological Surgeons Meeting, Duke University, May 2006. “Cerebrovascular Research: New Frontiers”, Dempsey R, Neurosurgery Symposium, Ann Arbor, MI, August 2006. “A Critical Role of Monocyte Chemoattractant Protein-1 (MCP-1) in Neuroblast Migration Following Focal Ischemia”, Dempsey R, Yan Y, Sailor K, Lang B, Park S, Vemuganti R, The American Academy of Neurological Surgery 68th Annual Meeting, Greensboro, GA, October 2006. “Putting Scientific Thoughts Together: What a Reviewer Looks for in a Grant of Manuscript”, Dempsey R, RUNN Course, October 2006.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 31 “Carotid Atherosclerosis: Is it the Key to Delayed Vascular Dementia”, Dempsey R, Rachidian Society Meeting, February 2007. “Discussion of Early Outcome Following Multi-modality Endovascular Rescure in Acute Stroke”, Dempsey R, American Association of Neurological Surgery, April 2007. “Report on the Society of Neurological Surgeons”, Dempsey R, Society of Neurological Surgeons Annual Meeting, May 2007. “Carotid Atherosclerosis-Frontiers for Neurosurgery”, Dempsey R, University of Utah, Department of Neurological Surgery Grand Rounds”, June 2007. International “Focal Cerebral Ischemia Stimulates Regional Changes in Prostaglandin and Polyamine Markers: Contribution to the Pathophysiology of Cerebral Infarction” Dempsey RJ, Roy MW, Meyer K, Tai H, Olson JW; 8th International Congress of Neurological Surgery, July, 1985. (Awarded World Federation of Neurosurgical Societies Young Neurosurgeon Award.) “The Metabolic and Nutritional Sequelae of Nonsteroid-Treated Head-Injured Patients” Young AB, Ott LG, Norton J, Rapp RP, Tibbs PA, Dempsey RJ; 8th International Congress of Neurological Surgery, July, 1985. “Limitations of Cyclooxygenase Inhibition in Transient Cerebral Ischemia” Dempsey RJ, Roy M, Maley ME; 11th International Joint Conference on Stroke and Cerebral Circulation, February, 1987. “Ischemic Brain Edema and Leukotriene Activity: Effect of Hypothermia” Dempsey RJ, Combs DJ, Maley ME, Cowen DE, Roy MW; 12th International Joint Conference on Stroke and Cerebral Circulation, February, 1987. “Ornithine Decarboxylase Activity and Immunohistochemical Location in Post-Ischemic Brain” Dempsey RJ, Maley B, Olson J, Cowen D, Maley M, Roy M; XIIIth International Symposium on Cerebral Blood Flow and Metabolism, June, 1987. “The Effect of Cerebral Edema on Reperfusion Blood Flow Deficit in Ischemic Animals” Cowen D, Combs D, Dempsey R; 7th Int’l Symposium on Intracranial Pressure and Brain Injury, June, 1988. “The Effect of Hyperglycemia on the Progression of Vasogenic Edema Following Cold Injury” Ott L, Combs D, Beard D, Dempsey R, Haack D, Young B; 7th International Symposium on Intracranial Pressure and Brain Injury, June, 1988. “Difluoromethylornithine Inhibition of Polyamine Synthesis Decreases Post-Ischemic Edema and Blood-Brain Barrier Breakdown” Schmitz M, Combs D, Dempsey RJ; 14th International Joint Conference on Stroke and Cerebral Circulation, February, 1989. “Relationship Between Glucose, Lactate and pH in Cerebral Ischemia” Combs DJ, Dempsey RJ, Maley M, Donaldson D, Smith C; 15th International Joint Conference on Stroke and Cerebral Circulation, February, 1990.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 32 “Inducible Ornithine Decarboxylase Expression in Brain Subject to Vasogenic Edema after Transient Ischemia: Relationship to c-fos Gene Expression” Dempsey R, Kindy M, Carney J; Brain Edema 1990, 8th International Symposium, June, 1990. “Ultra-Fast Magnetic Resonance Perfusion Mapping of Brain Infarction” Pettigrew C, Lee C, Dean B, Dempsey R, Kirsch J, Runge V; 16th International Joint Conference on Stroke and Cerebral Circulation, February, 1991. “Amount of Smoking Predicts Carotid Artery Atherosclerosis Independent of Age, Hypertension, and Diabetes” Dempsey R, Moore R; 16th International Joint Conference on Stroke and Cerebral Circulation, February, 1991. “Hyperglycemia Suppresses c-fos in RNA Expression Following Transient Cerebral Ischemia” Combs D, Kindy M, Donaldson D, Dempsey R; 16th International Joint Conference on Stroke and Cerebral Circulation, February, 1991. “Effect of Hyperglycemia on In Vivo 31P Spectroscopy During Transient Cerebral Ischemia” Dempsey R, Donaldson D, Combs D; Brain-91, XVth International Symposium on Cerebral Blood Flow and Metabolism, June, 1991. “A Causal Chain from Smoking to Stroke” Dempsey R, Moore R; 17th International Joint Conference on Stroke and Cerebral Circulation, January, 1992. “Clinical Prognosis of Vertebral Artery Occlusive Disease” Pettigrew C, Moore R, Lee C, Dempsey R; 18th International Joint Conference on Stroke and Cerebral Circulation, February, 1993. “New Adjuncts in Radiologic Evaluation-Carotid Duplex-TCD” Dempsey R; 18th International Joint Conference on Stroke and Cerebral Circulation, February, 1993. “Carotid Endarterectomy Noninvasive Imaging” Dempsey R; 18th International Joint Conference on Stroke and Cerebral Circulation, February, 1993. “Near Infrared Spectroscopy in the Carotid Endarterectomy Patient” Dempsey R, Kindy M, Lodder R, Moore R; Research Society of Neurological Surgeons, June, 1993. “Carotid Plaque Morphology and Clinical Characteristics” Dempsey R, Davis D, Lodder R, Moore R; 19th International Joint Conference on Stroke and Cerebral Circulation, February, 1994. “Blockade of Ornithine Decarboxylase Limits Ischemic Brain Damage” Dempsey RJ, Hu Y, Kindy M; 19th International Joint Conference on Stroke and Cerebral Circulation, February, 1994. “Lipoprotein Oxidation and Symptomatic Carotid Artery Atherosclerosis” Dempsey R, Lodder R, Davis D, Moore R; 20th Int’l Joint Conference on Stroke and Cerebral Circulation, February, 1995. “Increased Activity of Ornithine Decarboxylase and Edema Formation in the Hippocampus after Brain Injury” Dempsey RJ, Baskaya MK, Rao AM, Prasad MR; Brain-95, XVIIth International Symposium on Cerebral Blood Flow and Metabolism, Cologne, Germany, July, 1995.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 33 “S-adenosylmethoionine (SAM) Effects on Blood-Brain Barrier Breakdown and Neuronal Cell Survival after Transient Ischemia” Rao A, Baskaya M, Maley M, Prasad R, Kindy M, Dempsey R; 21st Int’l Joint Conference on Stroke and Cerebral Circulation, January, 1996, San Antonio, TX. “Near-Infrared Spectroscopy in Carotid Endarterectomy Patients: Lipoprotein Predictors of Disease” Dempsey R, Cassis L, Davis D, Lodder R; Joint Meeting, Society of British Neurological Surgeons and Neurosurgical Society of America, April, 1997, Cambridge, England. “The Pathophysiology and Regulation of the Glutamatergic System in Traumatic Brain Injury” Dempsey R, Rao VLR, Baskaya M, Rao A, Dogan A. The American Academy of Neurological Surgery and The Canadian Neurosurgical Society, September, 1997. “The Diagnosis and Treatment of Cerebral Aneurysms” Dempsey R. To The Regional College of Medicine, Ambato, Ecuador, February 1998. “Cerebral Protection for Ischemia During Neurosurgery” Dempsey R. Meditropoli Centro Medico, Quito, Ecuador, February 1999. “New Methods to Diagnose and Treat Intracranial Aneurysms” Dempsey R. Meditropoli Centro Medico, Quito, Ecuador, February 1999. “Functioning Na+-K+-2Cl- Cotransporter in Astrocytes” Su G, Dempsey R, Sun D. International Society for Neurochemistry, August 1999. “Combined Endovascular and Open Surgical Approaches to AVMs and Atherosclerotic Cerebrovascular Disease” Dempsey R. AVMAN Conference, Ankara University, Turkey February 2000 “Cerebral Protection During Intracranial Aneurysm Surgery” Dempsey R. AVMAN Conference, Ankara University, Turkey, February 2000. “Acute Ischemic Stroke of Undetermined Etiology in a University Hospital” Dulli D, Dixit S, Levine R, Dempsey R. International Stroke Meeting, Florida, February 2001. “Diagnostic Evaluation of Carotid Disease” Dempsey R. First American-Japanese Meeting for Surgical and Endovascular Treatement of Cardiovascular Disorders, Hawaii, February, 2001. “Transcriptional Profiling of Ischemic Rat Brain Using Gene Chips” Vemuganti R, Song G, Bowen K, Dempsey R, International Society for Neurochemistry, August 2001. “Gene Chip Analysis After Spinal Cord Injury” Song G, Cechvala C, Resnick D, Dempsey R, Vemuganti R, International Society for Neurochemistry, August 2001. “CDP-Choline Effect on Lipid Alterations After Transient Forebrain Ischemia” A Rao, J Hatcher, R Dempsey, International Society for Neurochemistry, August 2001. “Molecular Biology and the Medicine of the Future”, Dempsey R., Provincial Medical Society, Ambato, Ecuador, February 2002.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 34 “Cerebral Physiology in Health and Disease”, Dempsey R., Four lectures to Ecuador Medical Students, February 2002. “Can the Adult Brain Repair Itself after Ischemia?”, Dempsey R., Combined Neurosurgical Society of America and Society of British Neurological Surgeons, Kiawah, South Carolina, April 2002. “Regionally Specific Neurogenesis in Response to Focal Cerebral Ischemia”, Dempsey R., Sailor K., Bowen K., Rao V., Brain Edema 2002, Japan, November 2002. “Neurogenesis and Brain Edema Round-up”, Dempsey R., Brain Edema 2002, Japan, November 2002. “Tripdenyltetrazolium Staining Produces “False-Positive” Infarction in Mouse Focal Ischemia”, Tureyen K., Sailor K., Dempsey R., Turkish Neurosurgical Society Congress, 2003. “Anatomical Evaluation of the Consistency of Mouse Intraluminal Middle Cerebral Artery Occlusion Using Various Intraluminal Suture Diameters”, Tureyen K., Sailor K., Dempsey R., Turkish Neurosurgical Society Congress, 2003. “Correlation of Ultrasonic and Elastographic Parameters with Carotid Atherosclerotic Plaque Histopathology”, Shi H., Varghese T., Dempsey R., Salamat S., Zagzebski J., Frank G., 28th International Symposium on Ultrasonic Imaging and Tissue Characterization, 2003. Dempsey R., Four lectures to Ecuador Medical Students, February 2003. “Citocoline Attenuates Phospholipase A2 Activation and Hydroxyl Radical Generation in Transient Cerebral Ischemia”, Adibhatla R., Hatcher J., Dempsey R., International Society for Neurochemistry Meeting, May 2003. "Experimental Treatment of Vasospasm" Moderator, Dempsey R, 8th International Conference on Cerebral Vasospasm, Chicago, IL, 2003. "TGF-1 Signaling in Preconditioning-Induced Cerebral Ischemic Tolerance", Rao V, Dempsey R, 29th International Stroke Conference, February 2004. "Molecular Biology: Directing the Future of Medicine", Dempsey R, First International Course, Millennium Hospital, Ambato, Ecuador, February 2004. "Transient Focal Cerebral Ischemia Induces Neurogenesis in Adult Mouse Dentate Gyrus", Tureyen K, Vemuganti R, Sailor K, Bowen K, Dempsey R, Turkish International Meeting, 2004. "Exogenous Stimulators and Endogenous Mediators of Neurogenesis after Focal Ischemia in Adult Rat Brain", Vemugati,R.,Sailor,K.A., Tureyen,K., Bowen,K.K., Dempsey,R.J, II International Congress on Neuroregeneration, 2004 "Cortical and Striatal Migration of Endogenous Adult Stem Cells from the Sub-Ventricular Zone and Posterior peri-Ventricular Region in Response to Stroke", Dempsey R and Sailor K, Joint Meeting, American Academcy of Neurological Surgery and the German Society of Neurosurgery, Berlin and Dresden, Germany, October 2004.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 35 "Adult Neurogenesis after Stroke - Self Repair and Future Therapies", Dempsey R, Visiting Professor, XVIIIth Annual Marshall Lectureship, University of Toronto, January 2005. "Carotid Atherosclerosis and the Neurosurgeon, Past-Present and Future", Dempsey R, Visiting Professor, University of Toronto, January 2005. "Angiogenesis: The Pathophysiology of Carotid Plaque Emboli", Dempsey R, Tureyen K, Salamat S, Vemuganti R, 13th World Congress of Neurological Surgery, Marrakesh, Morocco, June 2005. “Increased Expression of Neurodegenerative Disease Related Genes in the Carotid Plaques from Symptomatic Stroke Patients”, Dempsey R, Vemuganti R, Hermann, B, XIV International Symposium on Atherosclerosis, Rome, Italy, June 2006. “Intracranial Pressure: From Anatomy to Diagnosis to Treatment”, Dempsey R, East African Neurosurgery Conference, Neurosurgery in the Company of the Big Five, Nairobi, Kenya, October, 2006. “Intracranial Aneurysms: New Treatment Modalities”, Dempsey R, East African Neurosurgery Conference, Neurosurgery in the Company of the Big Five, Nairobi, Kenya, October, 2006. “The Future of Endogenous Neuro Precursor Stem Cells in the Treatment of Stroke”, Dempsey R, East African Neurosurgery Conference, Neurosurgery in the Company of the Big Five, Maasai Mara, Kenya, October, 2006. “Collaborative Clinical Research: Improving Neurosurgical Care in Kenya”, Dempsey R, East African Neurosurgery Conference, Neurosurgery in the Company of the Big Five, Maasai Mara, Kenya, October, 2006. “The Way Forward”, Round table participant, East Central Southern African Regional Neurosurgical Training Program, October 2006. “Deducing a Role for Angiogenesis in Vulnerable Plaque: Increased Angiogenic Gene Expression in Carotid Artery Plaques from Sympotomatic Stroke Patients”, Dempsey R, 8th World Congress for Microcirculation, Milwaukee, WI, August 2007. “Cerebral Atherosclerosis, Pathophysiology of Disease and Window to Understanding the Treatment of Neurodegenerative Disorders”, Dempsey R, East Africa Symposium, Nairobi, Kenya, August 2007. “Brain Trauma, Pathophysiology and Determine Outcome”, Dempsey R, East Africa Symposium, Nairobi, Kenya, August 2007. RESEARCH AND CREATIVE PRODUCTIVITY Publications Journals
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 36 Elliot B, Smego D, Dempsey R, Dwyer R, Dubay D, Pillar T, Fry T: A colloquium on birth control. Notre Dame Science Quarterly 2:11, 1972. Dempsey R, Morgan J, Cohen L: Reduction of enzyme efflux from skeletal muscle by diethylstilbestrol. Clinical Pharmacology and Therapeutics 18:104-111.1975. Kohler J, Dempsey R, Simonowitz D: Hemorrhagic arteriovenous malformations in the colon of an adolescent. Surgical Rounds 3:73-74, 1980. Dempsey R, Chandler WF: Choroid plexus cyst in the lateral ventricle causing obstructive symptoms in an adult. Surgical Neurology 15(2):116-119, 1981. (February) Dempsey RJ, Kindt GW: Pathologic cerebral vasodilation and increased intracranial pressure in experimental hepatic encephalopathy. Surgical Forum 32:477-479, 1981. Ercius MS, Dempsey R, Chandler WF: Successful treatment of solitary thalamic abscess. Case report. Journal of Neurosurgery 56:865-867, 1982. (June) Dempsey RJ, Kindt GW: Experimental acute hepatic encephalopathy: The relationship of pathological cerebral vasodilation to increased intracranial pressure. Neurosurgery 10(6 PT 1):737-741, 1982. (June) Dempsey RJ, Kindt GW: Experimental augmentation of cerebral blood flow by mannitol in epidural intracranial masses. Journal of Trauma 22(6):449-454, 1982. (June) Dempsey RJ, Hopkins J, Bittman EL, Kindt GW: Total pinealectomy by an occipital parasagittal approach in sheep. Surgical Neurology 18(5):377-380, 1982. (November) Dempsey RJ, Chandler WF, Sauder SE: Surgically reversible hypothalamic hypopituitarism due to aqueductal stenosis. Case report. Journal of Neurosurgery 58:932-934, 1983. (June) Bittman EL, Dempsey RJ, Karsch FJ: Pineal melatonin secretion drives the reproductive response to daylength in the ewe. Endocrinology 113(6):2276-2283, 1983. Meyer KL, Dempsey RJ, Donaldson DL, Roy MW: Indomethacin-mediated improvement of somatosensory evoked potentials following middle cerebral artery occlusion: Effects of anesthesia. Surgical Forum 35:512-513, 1984. Dempsey RJ, Chandler WF: Abnormal serum melatonin levels in patients with intrasellar tumors. Neurosurgery 15(6):815-819, 1984. (December) Meyer KL, Dempsey RJ, Roy MW, Donaldson DL: Evoked potentials as a measure of experimental cerebral ischemia. Journal of Neurosurgery 62:269-275, 1985. (February) Dempsey RJ, Roy MW, Meyer KL, Donaldson DL: Indomethacin-mediated improvement following middle cerebral artery occlusion in cats: Effects of anesthesia. Journal of Neurosurgery 62:874-881, 1985. (June) Dempsey RJ, Roy MW, Cowen DE, Maley ME: Leukotrienes and edema after transient cerebral ischemia. Surgical Forum 36:495-497, 1985.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 37 Roy MW, Dempsey RJ, Meyer KL, Donaldson DL, Tibbs PA, Young AB: Effects of verapamil and diltiazem on acute stroke in cats. Journal of Neurosurgery 63:929-936, 1985. (December) Dempsey RJ, Roy MW, Meyer K, Tai H, Olson J: Polyamine and prostaglandin markers in focal cerebral ischemia. Neurosurgery 17(4):635-640, 1985. (October) Young B, Ott L, Norton J, Tibbs P, Rapp R, McClain C, Dempsey RJ: The metabolic and nutritional sequelae of the non-steroid-treated head injury patient. Neurosurgery 17:784-791, 1985. Dempsey RJ, Roy MW, Meyer K, Cowen DE, Tai H-H: Development of cyclooxygenase and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia. Journal of Neurosurgery 64:118-124, 1986. (January) McClain CJ, Twyman DL, Ott LG, Rapp RP, Tibbs PA, Norton JA, Kasarskis EJ, Dempsey RJ, Young B: Serum and urine zinc response in head-injured patients. Journal of Neurosurgery 64:224-230, 1986. (February) Dempsey RJ, Roy MW, Cowen DE, Maley ME: Lipoxygenase metabolites of arachidonic acid and the development of ischæmic cerebral oedema. Neurological Research 8:53-56, 1986. (March) Slevin JT, Sparks DL, Dempsey RJ, Davis DG, Hansaker JC III, DeKosky ST: Altered striatal dopaminergic metabolism 36 hours after unilateral trauma to the human mesencephalon. Neurology 37(2):322-325, 1987. (February) Dempsey RJ, Combs DJ, Maley ME, Cowen DE, Roy MW, Donaldson DL: Moderate hypothermia reduces postischemic edema development and leukotriene production. Neurosurgery 21(2):177-181, 1987. (August) Young B, Ott L, Haack D, Twyman D, Combs D, Oexmann JB, Tibbs P, Dempsey R: Effect of total parenteral nutrition upon intracranial pressure in severe head injury. Journal of Neurosurgery 67:76-80, 1987. (July) Young B, Ott L, Twyman D, Norton J, Rapp R, Tibbs P, Haack D, Bivins B, Dempsey R: The effect of nutritional support on outcome from severe head injury. Journal of Neurosurgery 67:668-676, 1987. (November) Goldsmith TL, Norton JA, Young AB, Tibbs PA, Dempsey RJ, Rapp RP: Safety and efficacy of metaclopramide in metrizamide myelography. Clinical Pharmacy 6:807-810, 1987. Cowen DE, Combs DJ, Dempsey RJ: Measurement of somatosensory evoked potential in the Mongolian gerbil: The effects of cerebral ischæmia.Neurological Research 9:159-163, 1987. (Sept.) Norton JA, Ott LG, McClain C, Adams L, Dempsey RJ, Haack D, Tibbs PA, Young AB: Intolerance to enteral feeding in the brain-injured patient. Journal of Neurosurgery 68:62-66, 1988. (January)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 38 Roy MW, Dempsey RJ, Cowen DE, Donaldson DL, Young AB: Thromboxane synthetase inhibition with imidazole increased blood flow in ischemic penumbra. Neurosurgery 22(2):317-323, 1988. Dempsey RJ, Roy MW, Cowen DE, Combs DJ: Polyamine inhibition preserves somatosensory evoked potential activity after transient cerebral ischæmia. Neurological Res 10:141-44,1988. (Sep) Dempsey R, Rapp RP, Young B, Johnson S, Tibbs P: Prophylactic parenteral antibiotics in clean neurosurgical procedures: A review. Journal of Neurosurgery 69:52-57, 1988. (July) Ott LG, Schmidt JJ, Young AB, Twyman DL, Rapp RP, Tibbs PA, Dempsey RJ, McClain CJ: Comparison of administration of two standard intravenous amino acid formulas to severely brain-injured patients. Drug Intelligence and Clinical Pharmacy 22:763-768, 1988. (October) Dempsey RJ, Combs DJ, Olson JW, Maley M: Brain ornithine decarboxylase activity following transient cerebral ischæmia: Relationship to cerebral oedema development. Neurological Research 10:175-178, 1988. (September) Dempsey RJ, Maley BE, Cowen D, Olson JW: Ornithine decarboxylase activity and immunohistochemical location in postischemic brain. Journal of Cerebral Blood Flow and Metabolism 8(6):843-847, 1988. Young AB, Ott LG, Beard D, Dempsey RJ, Tibbs PA, McClain CJ: The acute-phase response of the brain-injured patient. Journal of Neurosurgery 69:375-380, 1988. (September) Combs DJ, Ott L, McAninch PS, Dempsey RJ, Young B: The effect of total parenteral nutrition on vasogenic edema development following cold injury in rats.J Neurosurgery 70:623-627, 1989. (April) Kolpek JH, Ott LG, Record KE, Rapp RP, Dempsey R, Tibbs P, Young B: Comparison of urinary urea nitrogen excretion and measured energy expenditure in spinal cord injury and nonsteroid-treated severe head trauma patients. J Parenteral and Enteral Nutrition 13(3):277-280, 1989. (May-June) Young B, Ott L, Dempsey R, Haack D, Tibbs P: Relationship between admission hyperglycemia and neurologic outcome of severely brain-injured patients. Annals of Surgery 210(4):466-473, 1989. (Oct) Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ, Markesbery WR, MacDonald JS, Young B: A randomized trial of surgery in the treatment of single metastases to the brain. New England Journal of Medicine 322:494-500, 1990. (February) Combs DJ, Dempsey RJ, Maley M, Donaldson D: Relationship between plasma glucose, brain lactate and intracellular pH in cerebral ischemia. Stroke 21(6):936-942, 1990. (June) Dempsey RJ, Combs DJ, Donaldson DL, Thomas G, Smith C: In vivo 31phosphorus spectroscopy during transient cerebral ischæmia in the gerbil. Neurological Research 12:106-110, 1990. (June)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 39 Dempsey RJ, Diana AL, Moore RW: Thickness of carotid artery atherosclerotic plaque and ischemic risk. Neurosurgery 27(3):343-348, 1990. (September) Costello L, Combs DJ, Dempsey RJ: Unilateral carotid artery ligation in the Mongolian gerbil as a model for testing infarction-reducing therapies. Neurological Research 12:237-242, 1990. (Dec.) Combs D, Dempsey R, Kumar S, Donaldson D: Focal cerebral infarction in cats in the presence of hyperglycemia and increased insulin. Metabolic Brain Disease 5:169-178, 1990. Dempsey RJ, Carney JM, Kindy MS: Inducible ornithine decarboxylase expression in brain subject to vasogenic edema after transient ischemia: Relationship to c-fos gene expression. Acta Neurochir (Suppl) (1990) 51:189-191. Rapp R, Billeter M, Hatton J, Young B, Tibbs P, Dempsey R: Intravenous ciprofloxacin versus ceftazidime in treating nosocomial pneumonia and urinary tract infections. Clinical Pharmacy 10:49-55, 1991. Kindy MS, Carney JP, Dempsey RJ, Carney JM: Ischemic induction of protooncogene expression in gerbil brain. Journal of Molecular Neuroscience 2:217-228, 1991. Ott L, Young B, Phillips R, McClain C, Adams L, Dempsey R, Tibbs P, Ryo UY: Altered gastric emptying after head-injured patient: Relationship to feeding tolerance. Journal of Neurosurgery 74:738-742, 1991. (May) Dempsey RJ, Carney JM, Kindy MS: Modulation of ornithine decarboxylase mRNA expression following transient ischemia in the gerbil brain. Journal of Cerebral Blood Flow and Metabolism 11(6): 979-985, 1991. Combs DJ, Dempsey RJ, Donaldson D, Kindy MS: Hyperglycemia suppresses c-fos mRNA expression following transient cerebral ischemia in gerbils. Journal of Cerebral Blood Flow and Metabolism 12(1): 169-172, 1992. (January) Dean BL, Lee C, Kirsch JE, Runge VM, Dempsey RJ, Pettigrew LC: Cerebral hemodynamics and cerebral blood volume: MR assessment using gadolinium contrast agents and T1-weighted turbo-FLASH imaging. American Journal of Neuroradiology 12:39-48, 1992. (January- February) Dempsey RJ, Moore RW: Amount of smoking independently predicts carotid artery atherosclerosis severity. Stroke 23(5):693-696, 1992. (May) Riley WA, Barnes RW, Applegate WB, Dempsey R, Hartwell T, Davis VG, Bond MG, Furberg CD: Reproducibility of noninvasive ultrasonic measurement of carotid atherosclerosis: The asymptomatic carotid artery plaque study (ACAPS). Stroke 23(8):1062-1068, 1992. (August) Baker CW, Anderson KW, Beaty MM, Schwartz RW, Dempsey RJ: Decreased red blood cell membrane deformability in smokers and non-smokers with atherosclerosis. Clinical Hemorrheology 13:671-678, 1993. Dempsey RJ: New concepts in the management of cerebral vasospasm after subarachnoid hemorrhage. Current Surgery 50(8):587-592, 1993. (October)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 40 Schmitz MP, Combs DJ, Dempsey RJ: Difluoromethylornithine decreases postischemic brain edema and blood-brain barrier breakdown. Neurosurgery 33(5):882-888, 1993. (November) Prasad MR, Dhillon HS, Carbary T, Dempsey RJ, Scheff SW: Enhanced phosphodiestric breakdown of phosphatidylinositol bisphosphate after experimental brain injury. Journal of Neurochemistry 63(2):773-776, 1994. (August) Prasad MR, Ramaiah C, McIntosh TK, Dempsey RJ, Hipkens S, Yurek D: Regional levels of lactate and norepinephrine after experimental brain injury. J of Neurochemistry 63(3):1086-94, 1994. (Sep) Cai WM, Hatton J, Pettigrew LC, Dempsey RJ, Chandler MH: A simplified High-Performance Liquid Chromatographic method for direct determination of warfarin enantiomers and their protein binding in stroke patients. Therapeutic Drug Monitoring 16(5):509-512, 1994. (October) Dhillon HS, Donaldson D, Dempsey RJ, Prasad MR: Regional levels of free fatty acids and Evans blue extravasation after experimental brain injury. J of Neurotrauma 11(4):405-415, 1994. (Aug) Kindy MS, Hu Y, Dempsey RJ: Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage. J Cerebral Blood Flow and Metabolism 14(6):1040-1045, 1994. (November) Dempsey RJ, Moore RW, Cordero S: Factors leading to early recurrence of carotid plaque after carotid endarterectomy. Surgical Neurology 43(3):278-283, 1995. (March) Adams HP, Byington RP, Hoen H, Dempsey R, Furberg C: Effect of cholesterol-lowering medications on progression of mild atherosclerotic lesions of the carotid arteries and on the risk of stroke. Cerebrovascular Diseases 5:171-177, 1995. Hall NC, Dempsey RJ, Carney JM, Donaldson DL, Butterfield DA: Structural alterations in synaptosomal membrane-associated proteins and lipids by transient middle cerebral artery occlusion in the cat. Neurochemical Research 20(10):1161-1169, 1995. (October) Dempsey R, Baskaya MK, Rao AM, Prasad MR: Increased activity of ornithine decarboxylase and edema formation in the hippocampus after brain injury. Presented at the XVIIth International Symposium on Cerebral Blood Flow and Metabolism, Cologne, Germany, July 1-6, 1995. Journal of Cerebral Blood Flow Metabolism 15 Supp 1, S727, 1995. Dhillon HS, Yang L, Padmaperuma B, Dempsey RJ, Fiscus RR, Prasad MR: Regional concentrations of cyclic nucleotides after experimental brain injury. Journal of Neurotrauma 12(6):1035-1043, 1995. (December) Rao AM, Baskaya MK, Maley ME, Prasad MR, Dempsey RJ: Ornithine decarboxylase activity and edema formation in cerebral ischemia of conscious gerbils. Journal of Neurochemistry 65(6):2639-2643, 1995. (December) Dhillon HS, Carbary T, Dose J, Dempsey RJ, Prasad MR: Activation of phosphatidylinositol bisphosphate signal transduction pathway after experimental brain injury: a lipid study. Brain Research 698(1-2):100-106, 1995. (November)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 41 Baskaya MK, Rao AM, Prasad MR, Dempsey RJ: Regional activity of ornithine decarboxylase and edema formation after traumatic brain injury. Neurosurgery 38(1):140-145, 1996. (January) Baskaya M, Rao AM, Prasad R, Dempsey R: Effect of ∝-difluoromethylornithine treatment on regional ornithine decarboxylase activity and edema formation after experimental brain injury. Journal of Neurotrauma 13:85-92, 1996. Young B, Ott L, Kasarskis E, Rapp R, Moles K, Dempsey RJ, Tibbs PA, Kryscio R, McClain C: Zinc supplementation is associated with improved neurologic recovery rate and visceral protein levels of patients with severe closed head injury. Journal of Neurotrauma 13(1):25-34, 1996. (January) Dempsey RJ, Davis DG, Buice RG Jr, Lodder RA: Biological and medical applications of near- infrared spectrometry. Applied Spectroscopy 50(2):18A-34A, 1996. (February) Baskaya MK, Prasad MR, Donaldson D, Hu Y, Rao AM, Dempsey RJ: Enhanced accumulation of free fatty acids in experimental focal cerebral ischemia. Prostaglandins Leukotrienes and Essential Fatty Acids. 54(3):167-171, 1996. (March) Baskaya MK, Hu Y, Donaldson D, Maley M, Rao AM, Prasad MR, Dempsey R: Protective effects of the 5-lipoxygenase inhibitor AA-861 on cerebral edema after transient ischemia. Journal of Neurosurgery. 85(1):112-116, 1996. (July) Hatton J, Lu WY, Rhoney DH, Tibbs PA, Dempsey RJ, Young B: A step-wise protocol for stress ulcer prophylaxis in the neurosurgical intensive care unit. Surg Neurology. 46:493-499, 1996. (Nov) Dempsey RJ, Baskaya MK, Combs DJ, Donaldson D, Rao AM, Prasad MR: Delayed hyperglycemia and intracellular acidosis during focal cerebral ischemia in cats.Acta Neurochir 138(6):745-51, 1996. Dempsey RJ, Baskaya MK, Combs D, Donaldson D, Rao AM, Prasad MR: Effect of hyperglycemia on reperfusion-associated recovery of intracellular pH and high energy phosphates after transient cerebral ischemia in gerbils. Neurological Research. 18(6):546-552, 1996. (December) Hatton J, Lu WY, Rhoney DH, Tibbs PA, Dempsey RJ, Young B: A step-wise protocol for stress ulcer prophylaxis in the neurosurgical intensive care unit. Surg Neurol 46(5):493-499, 1996. (Nov) Badie B, Dempsey RJ: Treatment of brain tumors: Making progress? Wisconsin Medical Journal 95(12):851, 1996. (December) Young B, Moore WS, Robertson JT, Toole JF, Ernst CB, Cohen SN, Broderick JP, Dempsey RJ, Hosking DJ: An analysis of perioperative surgical mortality and morbidity in the asymptomatic carotid atherosclerosis study. Stroke 27:2216-2224, 1996. (December) Baskaya MK, Rao AM, Dogan A, Donaldson D, Gellin G, Dempsey RJ: Regional brain polyamine levels in permanent focal cerebral ischemia. Brain Research. 744(2):302-308, 1997. (January)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 42 Rao AM, Baskaya MK, Maley ME, Kindy MS, Dempsey RJ: Beneficial effects of S-adenosyl- L-methionine on blood-brain barrier breakdown and neuronal survival after transient cerebral ischemia in gerbils. Molecular Brain Research. 44(1):134-138, 1997. (February) Baskaya MK, Rao AM, Donaldson D, Prasad MR, Dempsey RJ: Protective effects of ifenprodil on ischemic injury size, blood-brain barrier breakdown, and edema formation in focal cerebral ischemia. Neurosurgery. 40(2):364-370, 1997. (February) Hatton J, Rapp RP, Kudsk KA, Brown RO, Luer MS, Bukar JG, Chen SA, McClain CJ, Gesundheit N, Dempsey RJ, Young B: Intravenous Insulin-like Growth Factor-I (IGF-I) in moderate-to-severe head injury: a Phase II safety and efficacy trial. Journal of Neurosurgery 86(5):779-786, 1997. (May) Baskaya MK, Rao AM, Dogan A, Donaldson D, Dempsey RJ: The biphasic opening of the blood- brain barrier in the cortex and hippocampus after traumatic brain injury in rats. Neuroscience Letters 226(1):33-36, 1997. (April) Dogan A, Rao AM, Baskaya MK, Rao VL, Rastl J, Donaldson D, Dempsey RJ: Effects of ifenprodil, a polyamine site NMDA receptor antagonist, on reperfusion injury after transient focal cerebral ischemia. Journal of Neurosurgery 87(6):921-926, 1997 (December) Baskaya M, Dempsey R: Brain protection during cerebrovascular surgery. Perspectives in Neurological Surgery 8(1):95-113, 1997. Dempsey R, Cassis L, Davis D, Lodder R: Near infrared imaging and spectroscopy in stroke research: Lipoprotein distributions and disease. Ann. NY Acad. Sci., 820:149-169, 1997. Rao VLR, Baskaya MK, Rao AM, Dogan A, Dempsey RJ: Increased ornithine decarboxylase activity and protein level in the cortex following traumatic brain injury in rats. Brain Research 783(1):163-166, 1998. (February) Biller J, Feinberg WM, Castaldo JE, Whittemore AD, Harbaugh RE, Dempsey RJ, Caplan LR, Kresowik TF, Matchar DB, Toole JF, Easton JD, Adams HP, Brass LM, Hobson RW, Brott TG, Sternau L: Guidelines for carotid endarterectomy--A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart. Circulation 97(5):501-509, 1998 and Stroke 29(2):554-562, 1998. (February) Rao VLR, Baskaya MK, Dogan A, Rothstein JD, Dempsey RJ: Traumatic brain injury down- regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain. Journal of Neurochemistry 70(5);2020-2027, 1998. (May) Dogan A, Baskaya M, Rao VLR, Rao A, Dempsey R: Intraluminal suture occlusion of middle cerebral artery in spontaneously hypertensive rats. Neuroscience Research 20:265-270, 1998. (April) Rao A, Hatcher J, Dogan A, Dempsey R: Fluorometric assay of nitrite and nitrate in brain tissue after traumatic brain injury and cerebral ischemia. Brain Research 793:265-270, 1998. (May)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 43 Woodward D, Hatton J, Ensom M, Young B, Dempsey R, Clifton G: ∝-1 acid glycoprotein and CNS distribution following subarachnoid hemorrhage. Pharmacotherapy 18;1062-1068, 1998. (November) Rao A, Hatcher J, Baskaya MK, Dempsey RJ. Simultaneous assay of ornithine decarboxylase and polyamines after central nervous system injury. Neuroscience Letters 272:63-66, 1998 (November) Patchell R, Tibbs P, Regine W, Dempsey R, Mohiuddin M, Kryscio R, Foon K, Markesbery W, Young B. Postoperative radiotherapy in the treatment of single metastases to the brain. Journal of the American Medical Association 280:1485-1489, 1998 (November) Rao A, Hatcher J, Dempsey R. CDP-Choline: Neuroprotection in Transient Forebrain Ischemia of Gerbils. Journal of Neuroscience Research 58:, 1999. Rao A, Hatcher J, Kindy M, Dempsey R. Arachidonic Acid and Leukotriene C4: Role in Transient Cerebral Ischemia of Gerbils. Neurochem Research 24:1227-1234, 1999 (October) Baskaya M, Dogan A, Dempsey R. Application of endovascular suture occlusion at middle cerebral artery in gerbils to obtain consistent infarctions. Neurological Research 21:574-578, 1999 (September) Sandin J, Salamat S, Baskaya M, Dempsey R. Intracerebral hemorrhage due to the rupture of a nontraumatic middle meningeal artery aneurysm. Journal of Neurosurgery. 90:951-955, 1999 (May) Dogan A, Rao A, Baskaya M, Hatcher J, Temiz C, Vemuganti R, Dempsey R. The contribution of polyamine oxidase brain injury after trauma. Journal of Neurosurgery 90:1078-1082, 1999. (June) Vemuganti R, Dempsey R. Traumatic injury to cat brain upregulates neuronal nitric oxide synthase expression and L-[3H] nitro-organic binding. Journal of Neurotrauma 16:865-877, 1999 (October) Furlan A, et al. Intra-arterial Prourokinase for Acute Ischemic Stroke. JAMA 282:2003-2011, 1999 (December) Dogan A, Rao AM, Hatcher J, Rao R, Baskaya MK, Dempsey RJ. Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. Jrnl of Neurochemistry 72:765-770, 1999. Dogan A, Eras M, Rao V, Dempsey R. Protective effects of memantine against ischemia- reperfusion injury in spontaneously hypertensive rats. Acta Neurochirurgica 141:1107-1113, 1999. Rao A, Hatcher J, Dempsey R. “Polyamine response to CNS injury: For better or for worse?” Recent Res Devel Neurochem 2:517-532, 1999. Rao A, Hatcher J, Dempsey R. “Lipid metabolism in ischemic neuronal death.” Recent Res Devel Neurochem 2:533-549, 1999.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 44 Su G, Dempsey RJ, Sun D. Inhibition of Na+-K+-2C1- cotransporter in astrocytes enhances intracellular [3H]-L-glutamate accumulation and attenuates [3H]-D-aspartate release in high [K+]0. Society for Neuroscience 25 (part 1): 1037: 1999. Dempsey R, Baskaya M, Dogan A. “Attenuation of Brain Edema, Blood-Brain Barrier Breakdown and Injury Volume by Ifenprodil, a Polyamine-site N-methyl-o-asparatate Recepter Antagonis, after Experimental Traumatic Brain Injury in Rats.” Neurosurgery 47:399-406, 2000 (August). Rao A, Hatcher J, Dempsey R. Neuroprotection by Group I Metabotropic Glutamate Receptor Antagonists in Forebrain Ischemia of Gerbil. Neuroscience Letters, 2000. Rao A, Hatcher J, Dempsey R. Lipid Alterations in Transient Forebrain Ischemia: Possible New Mechanisms in CDP-Choline Neuroprotection. Journal of Neurochemistry 75:2528-2535, 2000 (Dec). Baskaya M, Dogan A, Rao A, Dempsey R. Neuroprotective Effects of CAP-Choline on Brain Edema and Blood Brain Barrier Breakdown After Traumatic Brain Injury. Journal of Neurosurgery 92:448-452, 2000 (March) Baskaya M, Dogan A, Temiz C, Dempsey R. Application of 2,3,5-triphenyltetrazolium chloride (TTC) staining to evaluate injury volume after controlled cortical impact brain injury: Role of brain edema in evaluation of injury volume. Journal of Neurotrauma 17:93-97, 2000 Rao A, Hatcher J, Dogan A, Dempsey R Elevated N’acetylspermidine levels in gerbil and rat brains after CNS injury. Journal of Neurochemistry 74:1106-1111, 2000. Rao VL, Rao AM, Dogan A, Bowen K, Hatcher J, Rothstein J, Dempsey R. Glial Glutamate Transporter GLT-1 Down-regulation Precedes Delayed Neuronal Death in Gerbil Hippocampus Following Transient Global Cerebral Ischemia. Neurochem Int 36:531-537, 2000. Rao VL, Dogan A, Bowen K, Dempsey R. Traumatic brain injury leads to increased expression of peripheral type benzodiazopine receptors, neuronal death and activation of astrocytes and microglia in rat thalamus. Experimental Neurology 161:102-114, 2000. Su G, Haworth R, Dempsey R, Sun D. Regulation of Na+ - K+ - Cl- Cotransporter in Primary Astrocytes by Dibutyryl cAMP and High [K+]. American Journal of Physiology: Cell Physiology 279:C1710 – C1721, 2000. Babu G, Sailor K, Sun D, Dempsey R. Spermidine/spermine N’acety/transferace activity in rat brain following transient focal cerebral ischemia and reperfusion. Neuroscience Letters. 300:17-20, 2001. Rao V, Dogan A, Todd K, Bowen K, Rothstein J, Dempsey R. Antisense Knockdown of the Glial Glutamate Transporter GLT-1 but not Neuronal Glutamate Transpoerter EAAC1 Exacerbates Transient Focal Cerebral Ischemica-Induced Neruonal Damage in Rat Brain. Journal of Neuroscience 21:1876-1883, 2001.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 45 Dulli D, Dempsey RJ, Levine R, Attitudes and Approaches to Acute Ischemia Stroke in Wisconsin Hospitals. Wisconsin Medical Journal 100:44-49, 2001 (September). Rao V, Dogan A, Bowen K, Todd K, Dempsey R, Glial Glutamate Transporter GLT-1 Knockout Exacerbates Hippocampal Neuronal Damage Following Traumatic Injury to Rat Brain. Eur J Neurosciences 13:119-128, 2001. Yan Y, Dempsey R, Sun D. Na+-K+-Cl- Cotransporter in Rat Rocal Ischemia. Journal of Cerebral Blood Flow & Metabolism 21:711-721, 2001. Rao V, Dogan A, Bowen K, Rao A, Hatcher J, Dempsey R. Ornithine Decarboxylase Knockdown Exacerbates Transient Focal Cerebral Ischemia Induced Neuronal Damage in Rat Brain. Journal of Cerebral Blood Flow & Metabolism 21:945-954, 2001 (August). Rao A, Bowen K, Dempsey R. Transient Focal Cerebral Ischemia Down-regulates Glutamate Transporters GLT-1 and EAAC1 Expression in Rat Brains. Neurochemical Research 26:497-502, 2001 (May). Rao A, Hatcher J, Dempsey R. Does CAP-Choline Modulate Phospholipase Activities? Brain Research 893:268-272 (2001). Yan Y, Dempsey R, Sun D. Expression of Na+-K+-Cl- Cotransporter in Rat Brain During Development of Its Localization in Mature Astrocytes. Brain Research (Accepted) 2001. Zhang YL, Jiang B, Dempsey RJ. Ornithine decarboxylase expression after transient global ischemia in the gerbil. Brain Research 64:451-458, 2001. Rao V, Dogan A, Todd K, Bowen K, Dempsey R, Neuroprotection by memantine, a noncompetitive NMDA receptor antagonist after traumatic brain injury in rats. Brain Research 911:96-100, 2001. Rao V, Bowen K, Rao A, Dempsey R. Up-Regulation of the Peripheral-type Benzodiazepine Receptor Expression and [3H] Pk11195 Binding in Gerbil Hippocampus Following Transient Forebrain Ischemia. Journal of Neuroscience Research (Accepted) Kim B, Rao V, Sailor K, Bowen K, Dempsey R. Glial Cell Line-Derived Neurotropic Factor Protects Hippocampal Neurons after Traumatic Brain injury in Rats. Journal of Neurosurgery (Accepted) Rao A, Hatcher J, Dempsey R. Effects of Citicaline on Phospholipid and Glutathione Levels in Transient Cerebral Ischemia. Stroke, 32, (2376-2381) October 2001. Song G, Cechvala C, Resnick D, Dempsey R, Rao V. Gene Expression Analysis After Acute Spinal Cord Injury in Rat. Journal of Neurochemistry 79:1-13, November 2001. Adibhatla RM, Hatcher J, Dempsey R. Citicoline: Neuroprotective Mechanisms in Cerebral Ischemia. Journal of Neurochemistry 80:12-23, January 2002. Adibhatla RM, Hatcher J, Sailor K, Dempsey R. Polyamines and CNS Injury: Spermine and Spemadine Decrease Following Transient Focal Cerebral Ischemia in Spontaneously Hypertensive Rats, Brain Research 938:81-86, May 2002.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 46 Arfanakis K, Haughton VM, Carew JD, Rogers BP, Dempsey RJ, Meyerand ME. Diffusion Tensor MR Imaging in Diffuse Axonal Injury, AJNR AM J Neuroradiol 23(5):794-802, May 2002. Song G, Dhodda V, Blei A, Dempsey R, Rao V. Gene Chip Analysis Shows Altered mRNA Expression of Transcripts of Neurotransmitter and Signal Transduction Pathways in the Cerebral Cortex of Portacaval Shunted Rats, Journal of Neuroscience Research 68:730-737, June 2002. Dempsey R. Balance in a Young Neurosurgeon’s Life, Young Neurosurgeons News, Spring 2002. Adibhatla RM, Hatcher JF, Dempsey RJ. Citocoline: Mechanisms and Stroke Clinical Trials. Neurology http://www.neurology.org/cgi/eletters/57/9/1595, 2002. Rao VLR, Bowen KK, Dhodda V, Song G, Franklin J, Dempsey R. Gene Expression Analysis of Spontaneously Hypertensive Rat Cerebral Cortex Following Transient Focal Cerebral Ischemia, J Neurochem, 83(5):1072-86, 2002. Yan Y, Dempsey R, Flemmer A, Forbush B, Sun D. Inhibition of Na+-K+-Cl- Cotransporter during Focal Cerebral Ischemia Decreases Edema and Neuronal Damage. Brain Research 71:208-219, 2003. Dempsey R, Rao V. Cytidinediphosphocholine Treatment Decreases Traumatic Brain Injury- Induced Hippocampal Neuronal Death Cortical Contusion Volume and Neurological Dysfuntion in Rat, Journal of Neurosurgery 98:867-873, April 2003. Rao VLR, Dhodda V, Song G, Bowen KK, Dempsey R. Traumatic Brain Injury-induced Acute Gene Expression Changes in Rat Cerebral Cortex Identified by GeneChip® Analysis. Journal of Neuroscience Research. 71:208-219, 2003 Rao M Adibhatla , Hatcher J, Dempsey R. Phospholipase A2, Hydroxyl Radicals and Lipid Peroxidation in Transient Cerebral Ischemia, in Antioxidants and Redox Signaling. 5: 647-654 , 2003. Rao VLR, Bowen KK, Dhodda V, Song G, Franklin J, Dempsey R. Microarray analysis of the gene expression changes in rat brain after focal ischemia. Journal of Neurochemistry. 83:1072-1086, 2003 Temiz Cuneyt, Tan K, Ugar Hasan, Dempsey R, Egemen N. L-Argińinē in Focal Cerebral Ischemia, Neurosurgical Research. 25(5):465-70, July 2003. Temiz C, Dogan A, Baskaya M, Dempsey R. Dose-dependent Effect of Difluoromethylornithine on Reperfusion Injury after Temporary Middle-Cerebral Artery Occlusion, Clinical Neuroscience, 87(3):581-97, November 2003. Dempsey R, Sailor K, Bowen K, Vemuganti R. Stroke-induced Progenitor Cell Proliferation in Adult Spontaneously Hypertensive Rat Brain: Effect of Exogenous IGF-1 and GDNF, Journal of Neurochemistry, 8:586-597, 2003.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 47 Dempsey RJ, Sailor K, Bowen K, Rao V. Osteopontin Infusion into Normal Adult rat Brain Fails to Increase Cell Proliferation in Dentate Gyrus and Subventricular Zone. Brain Edema XII: Supplement Acta Neurochirurgica (2003) [Suppl] 86:181-185. Babu N, Sailor K, Beck J, Sun D, Dempsey R. Ornithine Decarboxylase Activity in In Vito and In Vitro Models of Cerebral Ischemia, Neurochemical Research. 28(12) 1851-1857, December 2003. Vemuganti R, Dempsey R, Bowen K. Inhibition of Intercellular Adhesion Molecule-1 Protein Expression by Antisense Oligonucleotides is Neuroprotective after Transient Middle Cerebral Artery Occlusion in Rat, Stroke, 35:179-184, 2004. Tureyen K, Vemuganti R, Sailor K, Dempsey R. Infarct Volume Quantification in Mouse Focal Cerebral Ischemia: A comparison of Triphenyltetrazolium Chloride and Cresyl Violet Staining Techniques, Journal of Neuroscience Methods 139:203-207, 2004. Tureyen K, Vemuganti R, Sailor K, Bowen K and Dempsey R. Transient Focal Cerebral Ischemia-Induced Neurogenesis in the Dentate Gyrus of the Adult Mouse, J Neurosurgery, 101:799-805, 2004. IHAST Investigators. Mild Intraoperative Hypothermia during Intracranial Aneurysm Surgery does not Improve Neurologic Outcome, NEJM, December 2004. Griffith S, Pozniak M, Mitchell C, Ledwidge M, Dempsey R, Peters A, Taylor E. Intraoperative Sonography of Intracranial Arteriovenous Malformations - How We Do It, J Ultrasound Med 23:1065-1072·0278-4297. Tureyen K, Vemuganti R, Sailor K, Dempsey R. Ideal Suture Diameter is Critical for Consistent Middle Cerebral Artery Occlusion in Mice, Neurosurgery. (1 Supply) 56:196-200, January 2005. Rao M Adibhatla , Hatcher J, Dempsey R. Cytidine-5'-diphosphocholine Affects CTP:Phosphocholine Cytidylyltransferase and Lyso-Phosphatidylcholine after Transient Brain Ischemia, Journal of Neuro science Research 76(3):390-6, 2004 Vemuganti R and Dempsey R. Carotid Atherosclerotic Plaques from Symptomatic Stroke Patients Share the Molecular Fingerprints to Develop in a Neoplastic Fashion: A Microarray Analysis Study, Neuroscience 131: 359-374, (2005). Todd M, Hindman B, Clarke W, Torner J, for the Intraoperative Hypothermia for Aneurysm Surgery Trial (IHAST) Investigators. "Mild Intraoperative Hypothermia during Surgery for Intracranial Aneurysm, The New England Journal of Medicine, 352; 2:135-145, January 2005. Temiz C, Dogan A, Baskaya MK, Dempsey RJ. Effect of difluoromethylornithine on reperfusion injury after temporary middle cerebral artery occlusion. Journal of Clinical Neuroscience. 12: 449-452, 2005. Kalluri HS, Vemugani R, Dempsey RJ. Lack of Response to EGF in Adult Neural Progenitor Cells, NEURO-REPORT, 16:8:835-838, May 2005.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 48 Naylor M, Bowen K, Sailor K, Dempsey RJ, Vemuganti R. Preconditioning-induced ischemic tolerance stimulates growth factor expression and neurogenesis in adult rat hippocampus, NEUROCHEMISTRY International, 47:565-572, 2005. Vemuganti R, Dempsey RJ. Increased expression of genes that control ionic homeostasis, second messenger signaling and metabolism in the carotid plaques from patients with symptomatic stroke, J. Neurochem., 10.1111/j.1471-4159, 2005. Tureyen K, Vemuganti R, Bowen K, Sailor K, Dempsey R. EGF and FGF-2 Infusion Increases Post-ischemic Neural Progenitor Cell Proliferation in Adult Rat Brain, Neurosurgery 2005 Dec;57(6):1254-63; discussion 1254-63. Dempsey R, Moftakhar R, Pozniak M. Intraoperative Doppler to Measure Cerebrovascular Resistance as a Guide to Complete Resection of Arterial Venous Malformations., Neurosurgery (Accepted) Tureyen K, Vemuganti R, Salamat S, Dempsey R. Increased Angiogenesis and Angiogenic Gene Expression in Carotid Artery Plaques from Symptomatic Stroke Patients, Neurosurgery, 58:5, May 2006. Yan Y, Vemuganti R, Dempsey R, Sailor K. Insulin-Like Growth Factor-1 is an Endogenous Mediator of Focal Ischemia-Induced Neural Progenitor Proliferation, European Journal of Neuroscience, 24:45-54, 2006. Adibhatla R M, Hatcher, J F, Dempsey R J. Lipids and Lipidomics in Brain Injury and Diseases (Review) AAPS J. 8:E314-E321. Kalluri H, Dempsey R. Mechanism of IGF-I mediated proliferation of adult neural progenitor cells: Role of Akt, European Journal of Neuroscience 25:1041-1048, 2007. Dempsey R, Kalluri H. Ischemia induced Neurogenesis: Role of Growth Factors (Review), Clinics of North America 18(1):183-190, 2007. Yan Y, Sailor K, Lang B , Park S, Vemugani R, Dempsey R. Monocyte Chemoattractant Protein-1 plays a Critical Role in Neurobalst Migration following Focal Cerebral Ischemia. Journal of Cerebral Blood Flow and Metabolism 2007 Jun;27(6):1213-24. Shi H, Tu H, Dempsey R and Varghese T. Ultrasonic Attenuation Estimation in Small Plaque Samples Using a Power Difference Method. Ultrasonic Imaging 29:15-30, 2007. Submitted for Publication Haughton V, Turski P, Iskandar B, Dempsey R, Badie B, Chahal R. Clinical Utility of fMRI in the Preoperative Evaluation of Patients with Cerebral Lesions, Radiology (Submitted) Tureyen K, Sailor K, Dempsey R. Triphenyltetrazolium Staining Produces “False-Positive” Infarction in Mouse Focal Ischemia, Neurosurgical Research (Submitted) Tureyen K, Resnick D, Salamat S, Dempsey R. A New Surgical Approach to Upper Ventral Cervical Spinal Cord in Rats and Description of Selective Anterior Spinal Artery Occlusion, Journal of Neurosurgery (Submitted)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 49 Medow J, Dempsey R. Spontaneous Recanalizationof the Internal Carotid Artery: Implications for Surgical Repair, Journal of Neurosurgery (Submitted) Tureyen K, Vemuganti R, Sailor K, Dempsey R. Comparative Study of TTC and CV Staining Techniques for Quantification in Mouse Focal Cerebral Ischemia, Journal of Neurosurgery (Submitted) Kalluri H, Vemuganti R, Dempsey R. IGF-1 enhances the survival, but not the proliferation of adult neuroal progenitor cells, Molecular Pharmacology (Submitted) Trivedi M, Ward M, Hess T, Gale S, Dempsey R, Rowley H and Johnson S. Longitudinal changes in global brain volume between 79 and 409 days after traumatic brain injury: relationship with duration of coma, Journal of Neurotrauma (Submitted, January 2007). Dempsey R J, Baskaya M, Yan Y, Kalluri H. Growth Factors Enhance Neurogenesis after Traumatic Brain Injury, Department of Veterans Affairs (Submitted) Kalluri H, Vemuganti R, Dempsey R. Insulin like Growth Factor-I Enhances the Proliferatin/Survival of Adult Neural Progenitor Cells by Activating Akt, but not ERK, Biochemical Journal, (Submitted) Park S, Yan, Y, Satriotomo I, Vemuganti R, Dempsey R. Substance P promotes adult neural progenitor cell proliferation. (Accepted to Journal of Neurosurgery). Dempsey, RJ and Kalluri, H. Ischemia induced neurogenesis: Role of growth factors. (Review) Neurosurgery Clinics of North America 18:183-190, 2007. Kelley D, Meyerand M, Nelson D, Ramirez L, Dempsey R, Wolf A, Farhoud M, Alexander A and Davidson R. Individualized Whole Human Brain Stereolithography using MRI Reverse Engineering (Submitted to the American Journal of Radiology, April 2007). Wiltrout C, Lang B, Yan Y, Dempsey R and Vemuganti R. Repairing Brain after Stroke: A Reivew on Post-ischemic Neurogenesis. (Submitted to Neurochemistry International, April 2007). Medow J and Dempsey R. Ischemic Cerebral Edema. (Submitted to Neurosurgical Focus, Feburary 2007). In Preparation Medow J, Dempsey R. Physiological Basis for Vasoconstriction, in preparation for Neurosurgical Research. Kelley D, Meyerand M, Nelson D, Ramirez L, Dempsey R, Wolf A, Farhoud M, Alendar A and Davidson R. Creating Physical 3D Stereolithograph Models of Brain and Skull, in preparation for BMC Neuroscience. Books
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 50 Dempsey RJ, Schneider RC: The management of head injuries in sports. In: Sports Injuries: Mechanisms, Prevention and Treatment, Schneider RC, Kennedy JC, Plant ML, Flemming W (eds). Baltimore: Williams & Wilkins, 1985, pp 652-675. Cowen D, Combs D, Dempsey R: The effect of cerebral edema on reperfusion blood flow deficit in ischemic animals. In Intracranial Pressure and Brain Injury, Hoff J, Betz L (eds). Springer Verlag, 1989, pp 931-934. Ott L, Combs D, Beard D, Dempsey R, Haack D, Young B: The effect of hyperglycemia on the progression of vasogenic edema following cold injury. In: Intracranial Pressure and Brain Injury, Hoff J, Betz L (eds). Springer Verlag, 1989, pp 1020-1023. Dempsey RJ: Arachidonic acid derived leukotrienes in ischemic brain edema. In: Lipid Mediators in Ischemic Brain Damage and Experimental Epilepsy. Bazan NG (ed). Basel: Karger Publishing, 1990, pp 146-162. Dempsey R, Moore R: Risk factor modification for arterial occlusive disease and brain ischemia. In: Cerebrovascular Occlusive Disease and Brain Ischemia, Awad I (ed). American Association of Neurological Surgeons, 1992, pp 117-134. Dempsey RJ: Neurosonology. In: Neurological Surgery, Youmans J (ed). Philadelphia: W. B. Saunders Co, 1996, pp. 214-223. Dempsey RJ: Pathophysiology of Cerebral Ischemia. In: The Practice of Neurosurgery, Tindall G, Cooper P, Barrow D (eds). Baltimore: Williams and Wilkins, 1996, pp 1765-1774. Dempsey RJ: Intracranial aneurysm: Temporary arterial occlusion. In: Cerebrovascular Disease, Batjer HH (ed). Philadelphia: Lippincott-Raven Publishers, 1997, pp 929-937. Sandin JA III, Baskaya MK, Dempsey RJ: Management of lipid metabolism. In: Primer on Cerebrovascular Diseases, Welch KMA (ed). San Diego, Academic Press, 1997, pp 708-711. Turski P, Cordes D, Mock B, Wendt G, Sorenson J, Quigley M, Strother C, Dempsey R: Basic concepts of functional MR imaging and AVMs. In Neuroimaging Clinics of North America, Russell EJ and Meyer JR (eds). W.B. Saunders Company, Philadelphia, 1998;8 pp 371-381. Masciopinto JE, Badie B, Dempsey RJ. Ultrasonography of the nervous system. In: Neurosurgery: The Scientific Basis of Clinical Practice, Crockard, Hayward, Hoff (eds). Oxford: Blackwell Science. 2000, pp 817-828. Dogan A, Dempsey RJ. Diagnostic modalities for carotid artery disease. In: Neurosurgery Clinics of North America, Harbaugh RE, ed. Philadelphia: W.B. Saunders. April 2000, pp 205-220. Dempsey RJ, Dogan A. Recurrent carotid stenosis. In Youmans Neurological Surgery, Fifth Edition, Winn RH, ed. Philadelphia: W.B. Saunders. 2004, pp 1661-1668. Abstracts Dempsey R, Morgan J, Cohen L: The effect of diethylstilbestrol on enzyme efflux from mouse skeletal muscle. Journal of Clinical Pharmacology 15:557-558, 1975
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 51 Meyer KL, Dempsey RJ, Roy MW, Donaldson DL: The application of somatosensory evoked potentials to experimental cerebral ischemia. Neurosurgery 15:270, 1984 Dempsey RJ, Roy MW, Meyer KL, Donaldson DL, Young AB: Beneficial effects of indomethacin on ischemic edema, cerebral perfusion, and somatosensory evoked potential after experimental stroke. Neurosurgery 15:275, 1984 Ott L, Young B, Norton J, Rapp R, Tibbs P, Dempsey R: The metabolic and nutritional sequelae of non-steroid-treated head-injured patients. Journal of Parenteral and Enteral Nutrition 9:110, 1985 Dempsey R, Chandler WF, Sander SE: Surgically reversible hypothalamic hypopituitarism due to aqueductal stenosis. In: Annual Review of Hydrocephalus, Matsumato S (ed). Tokyo: Neuron Publishing Co., 1985, pp. 56-57 Dempsey RJ, Roy MW, Cowen D, Maley ME: Arachidonate metabolites in cerebral ischemia: A delicate balance. Neurosurgery 16:721-722, 1985 Dempsey RJ, Roy MW, Maley ME: Limitations of cyclooxygenase inhibition in transient cerebral ischemia. Stroke 17:130, 1986. Dempsey RJ, Roy MW, Meyer K, Tai H, Olson JW: Polyamine and prostaglandin markers in focal cerebral ischemia. Year Book of Critical Care Medicine, 1987 Dempsey RJ, Combs DJ, Maley ME, Cowen D, Roy M: Ischemic brain edema and leukotriene activity: Effect of hypothermia. Stroke 18:291, 1987 Patchell RA, Young AB, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, MacDonald JS: Surgery for single brain metastases: A prospective, randomized trial. Neurology 37(Suppl 1):308, 1987 Dempsey RJ, Maley B, Olson J, Cowen D, Maley M, Roy M: Ornithine decarboxylase activity and immunohistochemical location in post-ischemic brain. Journal of Cerebral Blood Flow and Metabolism 7(Suppl 1):573, 1987. Dempsey RJ: Does carotid artery stenosis predict cerebral ischemic risk? Neurosurgery 21:118, 1987. Norton J, Ott L, Adams L, Dempsey R, Tibbs P, Rapp B, Young B: Intolerance to enteral feeding in brain-injured patients: Possible mechanisms. Jrn of Parenteral and Enteral Nutrition 11:105, 1987. Ott L, Young B, Twyman D, Norton J, Rapp R, Tibbs P, Haack D, Bivins B, Dempsey R: Does nutritional support affect outcome from severe head injury: A reexamination. Journal of Parenteral and Enteral Nutrition 11:105, 1987. Young B, Ott L, Rhodes J, McClain C, Dempsey R, Tibbs P, Thompson J: Interleukin-2 and T lymphocyte levels predict infection in head injury patients. Neurosurgery 23:258-259, 1988.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 52 Dempsey RJ, Combs DJ, Olson J, Maley M: Ornithine decarboxylase activity and brain edema after transient cerebral ischemia. Neurosurgery 23:262, 1988. Ott L, Phillips R, Young B, McClain C, Dempsey R, Tibbs P, Ryo U: Altered gastric emptying after head injury and its relationship to feeding intolerance. Journal of Parenteral and Enteral Nutrition 13:135, 1989. Schmitz M, Combs D, Dempsey RJ: Difluoromethylornithine inhibition of polyamine synthesis decreases post-ischemic edema and blood-brain barrier breakdown. Stroke 20:146, 1989. Dempsey RJ, Kindy M, Combs D, Carney J: Induction of the proto-oncogene c-fos in reperfused brain after transient ischemia: Relationship to development of brain edema. Journal of Neurosurgery 72:345A,1990. Combs D, Dempsey R, Maley M, Donaldson D, Smith C: Relationship between glucose, lactate and pH in cerebral ischemia. Stroke 21:165, 1990. Dempsey R, Dean B, Lee C, Howard R, Dineen T, Pettigrew L, Runge V: Very rapid dynamic magnetic resonance imaging with Gd-DPTA of the cerebral vascular system. Neurosurgery 26:1081-1082, 1990. Wilson D, Dempsey RJ, John WJ: Rhaboid tumor of the conus medullaris. Journal of Neuropathology and Experimental Neurology 49:339, 1990. Combs DJ, Kindy M, Donaldson D, Dempsey R: Hyperglycemia suppresses c-fos mRNA expression following transient cerebral ischemia. Stroke 22(1):132, 1991. (January) Pettigrew C, Lee C, Dean B, Dempsey R, Kirsch J, Runge V: Ultra-fast magnetic resonance perfusion mapping of brain infarction . Stroke 22(1):142, 1991. (January) Dempsey R, Moore R: Amount of smoking predicts carotid artery atherosclerosis independent of age, hypertension, and diabetes. Stroke 22(1):150, 1991. (January) Dempsey R, Donaldson D, Combs D: Effect of hyperglycemia on in vivo phosphorus spectroscopy during transient cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism 11 (Suppl 2):5331, 1991. Dempsey R, Moore R: A causal chain from smoking to stroke. Stroke 23(1):144, 1992. (January) Dempsey R, Hu Y, Kindy M: Blockade of ornithine decarboxylase limits ischemic brain damage. Stroke 25(1):260, 1994. (January) Dempsey R, Davis D, Lodder R, Moore R: Carotid plaque morphology and clinical characteristics. Stroke 25(1):272, 1994. (January) Dempsey R, Lodder R, Davis D, et al: Lipoprotein oxidation and symptomatic carotid-artery atherosclerosis, Stroke 26:(1)170, 1995 (January)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 53 Rao VLR, Dogan A, Rothstein JD, Dempsey RJ. Decreased glial glutamate transporter GLT-1 protein levels in rat brain following transient middle cerebral artery occlusion. Journal of Neurochemistry 70 (Suppl):S68, 1998. Vemuganti R, Song G, Bowen K, Dempsey R. Transcriptional Profiling of Ischemic Rat Brain Using Gene Chips. Journal of Neurochemistry 78 (Suppl) 71, 2001. Song G, Cehcvala C, Resnick D, Dempsey R, Vemuganti R. Gene Chip Analysis After Spinal Cord Injury. Journal of Neurochemistry 78 (Suppl) 66, 2001. Rao A, Hatcher J, Dempsey R. CDP-Choline Effect on Lipid Alterations After Transient Forebrain Ischemia. Journal of Neurochemistry 78 (Suppl 1) 68, 2001. Adibhatla RM, Hatcher JF, Dempsey RJ. Citocoline: Clinical Efficacy and Mechanisms in Cerebral Ischemia? Soc. Neurosci. Abstr. 28:698.7, 2002. Dhodda VK, Sailor K, Dempsey RJ, Rao VLR. Novel Mediators of Ischemic Preconditioning Induced Neuroprotection. Journal of Neurochemistry 81 (Suppl 1) CP13-03, 2002. Rao VLR, Bowen KK, Dhodda VK, Dempsey RJ. Suppressor of Cytokine Signaling-3 (SOCS-3) is a Neuroprotective Gene Upregulated after Focal Ischemia. Society of Neuroscience Abstracts 696.13, 2002. Sailor KA, Rao VLR, Bowen KK, Dempsey RJ. IGF-1 Infuction Increases Ischemia-induced Cell Proliferation in Adult Rat Dentate Gyrus. Society for Neuroscience Abstracts 698.7, 2002. Shi H., Vargehese T, Dempsey R, Salamat S, Zagsebski J, Frank G. Correlation of Ultrasonic and Elastographic Parameters with Carotid Atherosclerotic Plaque Histopathology. Ultrasonic Imaging 25:54, 2003. Adibhatla RM, Hatcher J, Dempsey RJ. Citocholine Attenuates Phospholipase A2 Activation and Hydroxyl Radical Generation in Transient Cerebral Ischemia. Journal of Neurochemistry 85:9, 2003 (suppl). Adibhatla RM, Hatcher JF, Tureyen K, Tsao FH, Dempsey RJ: Does CDP-Choline Partly Counteract TNF-α Mediated Events after Stroke? Society for Neuroscience Abstract #455.10. Hatcher JF, Adibhatla RM, Tureyen K, Dempsey RJ: Beneficial Effects of Exogenous Spermine in Transient Focal Cerebral Ischemia. Society for Neuroscience Abstract #342.19. Tureyen K, Dempsey RJ, Bowen KK, Sailor KA, Iskandar BJ, Vemuganti R (2004) EGF and FGF-2 infusion increases post-ischemic progenitor cell proliferation in adult rat brain. Society for Neuroscience Abstracts 33.15 Bowen KK, Tureyen K, Sailor KA, Dempsey RJ, Vemuganti V (2004) Impaired hippocampal neural progenitor cell proliferation in adult interleukin-6 knockout mice. Society for Neuroscience Abstracts 35.15 Kalluri H, Sailor KA, Vemuganti R, Dempsey RJ (2004) Proliferation and gene expression profiles of neural stem cell cultures (neurospheres) from the DG and SVZ of adult rat brain. Society for Neuroscience Abstracts 832.19
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 54 Vemuganti R, Sailor KA, Tureyen K, Bowen KK, Dempsey RJ: Exogenous Stimulators and Endogenous Mediators of Neurogenesis after Focal Ischemia in Adult Rat Brain. II International Congress on Neuroregeneration, 2004. R.M. Adibhatla; J. Hatcher; K. Tureyen; F. Tsao; T. Heath; R. Dempsey (2005). Cytokine biology, lipid metabolism, and CDP-choline liposomes in stroke. Society for Neuroscience Abstracts 219.2 Dempsey R, Tureyen K, Salamat S, Vemuganti R: Angiogenesis: The Pathophysiology of Carotid Plaque Emboli, 13th World Congress of Neurological Surgery Abstracts (in press) Yan Y, Sailor K, Vemuganti R, Dempsey R: Increased IGF-1 Expression Plays a Role in Stroke- Induced Neurogenesis, Society for Neuroscience Abstracts (Accepted) Kalluri H, Vemuganti R, Dempsey R: Effect of IGF-1 on the Adult Neuroprogenitor Cells Isolated from Rat Brain, Society for Neuroscience Abstracts. Varghese T, Dempsey RJ, Mitchell C, Kliewer M, Salamat S: Elastographic Characterization of Atherosclerotic Carotid Plaque In-vivo, 2006 AIUM Annual Convention Abstracts (Accepted) Adibhatla R, Hatcher J, Larsen E, Chen Xinzhi, Sun D, Dempsey R: CDP-Choline Partly Restores the Phosphatidycholine Levels by Differently Affecting Secretory Phospholipase A2 IIA and CTPPhosphochoine Cytidylyltransferase after Stroke, American Society for Biochemistry and Experimental Biology Abstracts #90.13, April 2006, San Francisco, CA. Adibhatla R, Hatcher J, Larsen E, X. Chen, Sun D, Dempsey R: CDP-Choline Partly Restores the Phosphatidycholine Levels by Differently Affecting Secretory Phospholipase A2 IIA and CTPPhosphochoine Cytidylyltransferase after Stroke, Society of Neurochemistry Abstracts, March 2006, Portland OR. Adibhatla R, Hatcher J, Tureyen K, F. Tsao, Dempsey R (2005). Cytokines, lipid metabolism, and CDP-Choline in Stroke Abstracts, #219.2 Society for Neuroscience, 2005, Washington, D.C.) Kalluri, H., Eickstaedt, J and Dempsey RJ (2006) Effect of oxygen glucose deprivation on the proliferation of adult neural progenitor cells. 36th Annual meeting of the Society for Neurosci. Atlanta, GA.(Accepted and presented) Adibhatla RM, EC Larsen, JF Hatcher, RJ Dempsey (2006). CDP-choline restores the phosphatidylcholine levels by differentially affecting phospholipase A2 and CTP-phosphocholine cytidylyltransferase after focal cerebral ischemia. Soc. Neurosci. Oct 2006, Atlanta, GA. #314.8 (oral presentation) Adibhatla RM, Hatcher JF, Dempsey RJ, Kalluri H (2007). Mechanisms of action of D609: anti- proliferative effects mediated by PC-PLC/sphingomyelin. (Submitted to Soc. Neurosci.) Dempsey RJ, Kalluri H, Yan Y, Sailor KA, Vemuganti R (2007). IGF-I and FGF2 synergistically promote adult neural progenitor cell proliferation under normal and ischemic onditions (Brain 2007 and Brain PET 2007 Meeting, Osaka, Japan)
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 55 Book Reviews and Letters to the Editor Chandler WF, Dempsey R: Symptomatic choroid plexus cyst. Surgical Neurology 16:390, November, 1981 (letter to the editor). Goldstein S, Dempsey R: Cerebral Revascularization for Stroke, in Journal of Neurosurgery 63:814, 1985 (book review). Dempsey R: Microsurgery of Cerebral Veins, in J of Neurosurgery 64:683-684, 1986 (book review). Dempsey RJ, Roy MW: Effect of indomethacin in focal cerebral ischemia. Neurosurgical Forum, Journal of Neurosurgery 70:151, 1989. Dempsey RJ: Prophylactic parenteral antibiotics in neurosurgery. Neurosurgical Forum, Journal of Neurosurgery 70:151, 1989. Dempsey RJ, Rapp RP, Young B: Prophylactic parenteral antibiotics in neurosurgery. Neurosurgical Forum, Journal of Neurosurgery 70:152, 1989. Dempsey RJ: Pharmacology of Cerebral Ischemia 1988, in Neurosurgery 27:496-497, 1990 (book review). Dempsey RJ: Prevention and Treatment of Delayed Ischæmic Dysfunction in Patients with Subarachnoid Hæmorrhage, in Neurosurgery (book review). (In Press) Patchell R, Tibbs, Regine, Mohinddin, Krysern, Markesbery, Fenn, Young, Dempsey: Postoperative Radiotherapy for Single Brian Metastases. JAMA 281:1696, May 1999. Letter to the Editor GRANTS Active Neurogenesis after Stroke: Effect of Growth Factors. Robert J. Dempsey, M.D., Principal Investigator, National Institutes of Health, $367,000 (total), 7/1/07-6/30/08. Siblings with Ischemic Stroke Study. Robert J. Dempsey, M.D., Local Principal Investigator, National Institutes of Health, $6,000, 2001-2007. CDP-choline: Mechanisms in Cerebral Ischemia. Rao Adibhatla, Ph.D., Principal Investigator, Robert J. Dempsey, M.D., Co-Investigator, National Institutes of Health, $1,157,603 (total), 2003-2008. The Role of Na+/H+ Exchanges in Cerebral Ischemia. Dandan Sun, M.D., Ph.D., Principal Investigator, Robert J. Dempsey, M.D., Co-Investigator, National Institutes of Health, $1,137,798, 2003-2008. Microwave Hyperthermia of Brain Tumors. Robert J. Dempsey, M.D., Co-Principal Investigator, University of Wisconsin Cancer Center, $26,380, 5/1/05-
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 56 Na-K02Cl Cotransporter in Cerebral Ischemia, Dan Dan Sun, M.D., Ph.D., Principal Investigator, National Institutes of Health, $190,000/year, 2003-2007. fMRI of Neurobehavioral Recovery after TBI, Sterling Johnson, Principal Investigator, National Institutes of Health, $200,000/year, 2002-2007. Carotid Occlusion: Surgery Study (COSS), Robert J. Dempsey, M.D., Local Principal Investigator, The National Institutes of Health, $250,000, 2001-2007 GRANTS Pending Carotid Strain Imaging for Detection of Vulnerable Plaque, Robert Dempsey, M.D., Co- Investigator, National Institutes of Health, $1,812,120, 4/08-3/13 Mechanism of Post-Ischemic Neurogenesis leading to Functional Recovery, Robert Dempsey, M.D., Principal Investigator, National Institutes of Health, $1,837,500, 10/07-9/12 Structural Stability of Carotid Plaque and Cognition, Robert Dempsey, M.D., Principal Investigator, National Institutes of Health, $1,439,920, 2007-2011 The Mechanisms of Ischemia Induced Neural Progenitor Migration, Robert Dempsey, M.D., Principal Investigator, American Heart Association, $132,000 Mechanism of IGF-1 Mediated Proliferation and Differentiation of Adult Neural Progenitor Cells, Robert Dempsey, M.D., Co-Investigator, National Institutes of Health, $404,250 Prior Carotid Occlusion: Surgery Study (COSS), Robert J. Dempsey, M.D., Local Principal Investigator, The National Institute of Health, $250,000, 2001-2006. Polyamines in Cerebral Ischemia. Robert J. Dempsey, M.D., Principal Investigator, Rao Adibhatla, Ph.D., Co-Principal Investigator, American Heart Association, $130,000, 2003-2005. Role of Inflammatory Mediators and Transcription in Modulation. Neuronal Damage After Transient Focal Cerebral Ischemia. Rao Vemuganti, Robert Dempsey, American Heart Association, Bagher Foundation, $400,000, 2002-2005, National Center Research Program, $215,000, 2002-2004. Neurogenesis after Stroke: Effect of Growth Factors. Robert J. Dempsey, M.D., Principal Investigator, National Institutes of Health, $649,002 (total), 2002-2005. Elastographic Imaging of Artherosclerotic Plaque. Robert J. Dempsey, M.D., Co-Investigator. Tomy Varghese, Principal Investigator, $20,000, Howard Hughes Medical Institute, 2002-2003. Vitamin Intervention for Stroke Prevention. Robert J. Dempsey, M.D., Principal Investigator of University of Wisconsin site. James Toole, M.D., overall Principal Investigator, approved, $170,000, NIH, 1997-2003.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 57 Intraoperative Hypothermia for Aneurysm Surgery Trial 2. Robert J. Dempsey, M.D., (Local) Co-Principal Investigator, $60,000, NIH, 1999-2003. Role of Polyamines in Modulating Neuroplasticity after Transient Cerebral Ischemia. Robert J. Dempsey, M.D., Co-principal Investigator, American Heart Association, $100,000, 2001-2003. Glutamate Transporter Expression and Function in Transient Focal Cerebral Ischemia. Vemuganti Rao Ph.D. Principal investigator Robert J. Dempsey Co-Investigator, Approved $164,988, American Heart Association, 1999-2002. “Na+-K+-2Cl- Cotransporters in Cerebral Ischemia.” Dandan Sun, M.D., Ph.D., Principal Investigator, Robert J. Dempsey, M.D., Co-Investigator, approved, NIH. $602,977 (total), 1999-2002. Investigation of the Effects of Diethylstilbestrol and Other Stibene Derivatives on the Leakage of Enzymes from Skeletal Muscle. Robert J. Dempsey, L. Cohen, American Cancer Society, Institutional Grant #IN-41-0, approved and funded, 1976-1977. Effects of Nutritional Support in Head-Injured Patients. Robert J. Dempsey, M.D., A. Byron Young, M.D., UKMC Research Fund, Major Equipment Grant, approved and funded, $15,000, 1983. The Role of Lipoxygenase Inhibitors in Decreasing Infarction and Edema Formation after Transient Cerebral Ischemia. Robert J. Dempsey, M.D., Mark W. Roy, Ph.D., Biomedical Research Support Grant, approved and funded, $6,700, 1983-1984. A Comparison of the Acceptability, Utility, and Tolerance of Sustacal® versus Ensure® in Cerebrovascular Accident Patients. A. Byron Young, M.D., Linda G. Ott, M.S., Robert J. Dempsey, M.D., Mead-Johnson Nutritional Division, approved and funded, $14,000, 1984-1985. Limiting Cerebral Infarction after Transient Ischemia. Robert J. Dempsey, M.D., A. Byron Young, M.D., American Heart Association, Kentucky Affiliate, approved and funded, $17,733, 1984-1985. Effects of Leukotrienes on the Early Development of Ischemic Edema after Transient Global Ischemia. David E. Cowen, B.S., Robert J. Dempsey, M.D., B. E. Maley, College of Medicine Dean’s Research Fellowship, approved and funded, $7,500, 1985-1986. NMR Characterization of Ischemic Edema. W. A. Carr, S. Smith, Robert J. Dempsey, D. E. Cowen, Biomedical Research Support Grant, approved and funded, $4,000, 1985-1986. Pathophysiology of Polyamine Production in Transient and Focal Cerebral Ischemia. Robert J. Dempsey, M.D., PSP Research Fund, approved and funded, $11,000, 1985-1986. Comparative Efficacy of Medium Chain Triglyceride Blended I.V. Fat Emulsion 10% and Liposyn II in Mild to Moderately Stressed Patients Maintained on Total Parenteral Nutrition. Byron Young, M.D., Robert Rapp, Pharm.D., Phillip Tibbs, M.D., Linda Ott, M.S., Robert Dempsey, M.D., Daniel E. Kenady, M.D., Abbott Laboratories Research Grant, approved and funded, $72,000, 1985-1986.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 58 Role of Ca++ Channels and Arachidonate Metabolites in Stroke. Robert J. Dempsey, M.D., Mark W. Roy, Ph.D., Veterans Administration Merit Review, approved and funded, $56,437, 1985-1987. Neurophysiologic Changes Following Transient Cerebral Ischemia. Robert J. Dempsey, M.D., David E. Cowen, B.S., American Heart Association Student Scholarship in Cerebrovascular Disease, approved and funded, $1,500, 1986. Hyperglycemia Enhanced Ischemic Cerebral Edema — Involvement of Polyamines. David J. Combs, Ph.D., Robert Dempsey, M.D., PSP Research Fund, approved and funded, $8,000, 1986-1987. Polyamines in Stroke-Related Vasogenic Edema. Robert J. Dempsey, M.D., American Heart Association, Kentucky Affiliate, approved and funded, $18,043, 1986-1987. Pathologic sequelae of Incomplete Cerebral Ischemia. Robert J. Dempsey, M.D., NIH clinical Investigative Development Award, approved and funded, $316,200, 1986-1992. Transcranial Doppler Measurement of Vasospasm. Robert J. Dempsey, M.D., University of Kentucky Experimental Bond Equipment Fund, approved and funded, $19,160, 1987. Polyamines and Arachidonate Metabolites in Experimental Cerebral Ischemia. Robert J. Dempsey, M.D., Principal Investigator, VA Merit Review, approved and funded, $15,744, 1987-1990. Involvement of Leukotrienes in Cerebral Ischemic Edema. David J. Combs, Ph.D., Robert J. Dempsey, M.D., Louis Costello, American Heart Association Student Scholarship in Cerebrovascular Disease, approved and funded, $1,500, 1988. Cerebral Metabolic Recovery after Transient Ischemia in the Presence of Hyperglycemia: An In- Vivo NMR Spectroscopy Study. David J. Combs, Ph.D., Robert J. Dempsey, M.D., Stanford Smith, Ph.D., Dennis Haack, Ph.D., Biomedical Research Support Grant, approved and funded, $7,147, 1988-1989. Diabetes-Associated Hyperglycemia in Ischemic Stroke. David J. Combs, Ph.D., principal investigator, Robert J. Dempsey, M.D., co-investigator, Juvenile Diabetes Foundation International, approved and funded, $41,000 (1st year), 1988-1990. President’s Faculty Grand Award, funded, $7,500, 1988-1991. Effects of Growth Factors on Cerebral Ischemic Outcome. John Carney, Principal Investigator, Robert Dempsey, CoInvestigator, Ethicon Research Foundation, approved and funded, $48,000, 1989. Red Cell Rheology in Atherosclerotic Patients. Robert J. Dempsey, M.D., Richard W. Schwartz, Carl Baker, Mark Beaty, American Heart Association Student Scholarship in Cerebrovascular Disease, approved and funded, $1,500, 1990. Ornithine Decarboxylase and Ischemic Brain Edema. Robert J. Dempsey, M.D., principal investigator, National Institutes of Health, approved and funded, $413,690, 1990-1993.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 59 Evaluation of Gastric pH Control in Head Trauma Patients by Continuous Infusion of Cimetidine. Jimmi Hatton, Pharm.D., Robert Rapp, Pharm.D., Daniel Wermeling, Pharm.D., Byron Young, M.D., Robert Dempsey, M.D., Phillip Tibbs, M.D., John Walsh, M.D., Marcus Schmitz, M.D., Marc Sturgill, Pharm.D., no % effort, Smith Kline Beecham, $23,161, 1991-1992. The Effect of Protein Binding in Drug Distribution into the CNS Following Subarachnoid Hemorrhage. Jimmi Hatton, Pharm.D., G. Dennis Clifton, Pharm.D., Mary H. H. Chandler, Pharm.D., Byron Young, M.D., Robert Dempsey, M.D., Phillip Tibbs, M.D., Marcus Schmitz, M.D., no % effort, American College of Clinical Pharmacy, Mead-Johnson CNS Pharmacology Award, $10,000, 1991-1992. A Phase II Open Label, Randomized Controlled Study of rH-IGF-1 in Patients with Severe Head Injury. Robert Rapp, Pharm.D., Jimmi Hatton, Pharm.D., Byron Young, M.D., Robert Dempsey, M.D., Phillip Tibbs, M.D., John Walsh, M.D., Marcus Schmitz, M.D., Craig McClain, M.D., no % effort, Genentech, $199,000, 1991-1993. A Controlled Trial of Intravenous Plus Oral RS-87476 in Acute Non-hemorrhagic Cerebral Infarction. Robert J. Dempsey, M.D., L. Creed Pettigrew, M.D., Institute of Clinical Medicine, Syntex Research, approved and funded, $100,000, 1992-1993. Efficacy/Safety Study of Tirilazad Mesylate (U-74,006F) in Patients with Subarachnoid Hemorrhage. Robert J. Dempsey, M.D., Principal Investigator at U. of Kentucky, Upjohn, $100,000, 1992-1993. Asymptomatic Carotid Artery Plaque Study — Trial of Mevinolin and Aspirin in Atherosclerosis. Curt D. Furberg, principal investigator, Robert J. Dempsey, M.D., co-investigator at regional center, National Institutes of Health, approved and funded, $234,000 per year 89, 1988-1994. Master Agreement Proposal for Cerebrovascular Research — for Clinical Research Studies on Transient Ischemic Attack, Acute Ischemic Stroke, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Dementia Secondary to Cerebrovascular Disease. Robert J. Dempsey, M.D., principal investigator, National Institutes of Health — NINCDS, approved, 1989-1994. Near-IR Laser for Medical Imaging. Robert Lodder, principal investigator, Robert Dempsey, co- principal investigator, 0% effort, NIH, approved and funded, $126, 892, 1993-1994. Asymptomatic Carotid Artery Stenosis Collaborative Study. James Toole, principal investigator, Robert Dempsey, M.D., co-investigator at regional center, National Institutes of Health, approved and funded, $44,000 per year, 1986-1995. Metabolic Mediators of Cerebral Ischemic Edema. Robert J. Dempsey, M.D., principal investigator, Veterans Administration Merit Review, approved and funded, $208,400, 1990-1995. Warfarin-Aspirin Recurrent Stroke Study. J. P. Mohr, overall principal investigator, Robert J. Dempsey, M.D., principal investigator at University of Kentucky, approved and funded, $18,263,918 total, 1992-1995. Detection of Carotid Atherosclerotic Plaque Oxidation. Robert J. Dempsey, M.D., principal investigator, American Heart Association, Kentucky Affiliate, $27,000, 1993-1995.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 60 Master Agreement for the Clinical Evaluation of Investigational Antiepileptic Drugs NINDS 92-17, awarded to the University of Kentucky. A. Byron Young, M.D., principal investigator, National Institutes of Health, NINDS, approved, 1993-1997. (RJ Dempsey, MD, co-investigator, 1993-1995) Peripheral Vascular Disease in the VA HDL Intervention Trial (HIT). James Anderson, M.D., principal investigator, VAMC Cooperative Studies Program and Parke-Davis, approved and funded, $117,970 total, 1993-1998. (Robert Dempsey, M.D., co-investigator, 1993-1995) Patent Foramen Ovale in Cryptogenic Stroke Study. S. Homma, M.D., overall principal investigator, Robert J. Dempsey, M.D., principal investigator at University of Kentucky, National Institutes of Health, approved, 1994-1995. Pharmacokinetics and Safety of Tirilazad Mesylate at Doses of 6, 10, and 15 mg/Kg/day in Patients with Subarachnoid Hemorrhage. Robert J. Dempsey, M.D., principal investigator, approved and funded, $72,000, Upjohn Pharmaceuticals, 1994-1995. Phospholipases in Cerebral Ischemia. Rao M. Adibhatla, Ph.D., principal investigator, Robert J. Dempsey, M.D., co-investigator, approved and funded, $30,000, American Heart Association, Kentucky Affiliate, 1995. (Awarded for 1995-1997, but rescinded when Dr. Adibhatla moved from the University of Kentucky to the University of Wisconsin.) Alpha-1 Adrenergic Receptor in Traumatic Brain Injury. M. Renuka Prasad, Ph.D., principal investigator, Robert J. Dempsey, M.D., co-investigator, National Institutes of Health, approved and funded, $384,623, 1992-1996. Ornithine Decarboxylase and Ischemic Brain Edema. Robert J. Dempsey, M.D., principal investigator. National Institutes of Health, approved and funded, $480,235 total, 1993-1996. LES02-Assessment of the Efficacy and Safety of Eliprodil in Patients with Acute Ischemic Stroke. Robert J. Dempsey, principal investigator, approved, Lorex, 1995-1996. Safety/Efficacy Study of 15 mg/Kg/day Tirilazad Mesylate in North American Women with Subarachnoid Hemorrhage. Robert J. Dempsey, M.D., principal investigator, approved and funded, $203,060 (est. total), Upjohn Pharmaceuticals, 1995-1997. An Exploratory Study of Tirilazad Mesylate (6, 10 and 15 mg/Kg/day) in Male Patients with Subarachnoid Hemorrhage. Robert J. Dempsey, M.D., principal investigator, approved and funded, $203,060 (est. total), Upjohn Pharmaceuticals, 1995-1997. A Prospective, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Group Sequential-Design, Multicenter Study to Determine the Safety and Efficacy of Intravenously Administered SDZ EAA 497 in Hospitalized Patients with Severe Traumatic Brain Injury. Robert J. Dempsey, M.D., principal investigator, pending, Sandoz, 1995-1997. A Prospective, Multicenter, Dose-Ranging Study of Intra-Arterial Thrombolysis in Acute Middle Cerebral Artery Distribution Thromboembolic Stroke, Part II. Robert J. Dempsey, M.D., principal investigator, approved, $50,146 (est. total), Abbott Laboratories, 1996-1998.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 61 A Double-Blind, Placebo-Controlled, Parallel-Group, 3-Day Treatment and 3-Month Follow-Up, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Fosphenytoin (Cerebyx) in Patients with Acute Ischemic Stroke. Robert J. Dempsey, M.D., Douglas Dulli, M.D., co- principal investigators, approved, $110,000 (est. total), Parke-Davis, 1997-1998. An International, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess Over 3 Months the Safety and Efficacy and Pharmacoeconomics of an 800mg Loading Dose and Fine 200mg Maintenance Doses of GV150526 in the Treatment of Patients with a Clinical Diagnosis of Acute Stroke. Rob’t Dempsey, Principal Investigator, approved, Glaxo Wellcome, 1998. Glutamate Transporter Expression and Function in Transient Focal Cerebral Ischemia. Rao Vemuganti Ph.D., Principal Investigator, Robert J. Dempsey, Co-Investigator. $130,000, American Heart Association Affiliate, 1998-1999. Acute Cellular Response to Brain Injury. University of Wisconsin subcontract, with Robert J. Dempsey, M.D., as Principal Investigator, of University of Kentucky Program Project grant, “Mechanisms of Brain Injury and Its Systemic Sequelæ,” with A. Byron Young, M.D., as overall Principal Investigator, approved and funded, $30,277 (96-97) for UW subcontract, National Institutes of Health, 1994-2000. Ornithine Decarboxylase (ODC) and Ischemic Brain Edema. Robert J. Dempsey, M.D., principal investigator, approved, $532,725 (total), NIH, 1997-2000. SB 214857/030-Blockade of the GP 11B/111A Receptor to Avoid Vascular Occlusion (BRAVO). David Ende, M.D., Robert J. Dempsey, M.D., Co-Principal Investigators, $84,000, Smith Kline Beecham, 1999-2002. A Double-Blind, Placebo-Controlled, Safety, Efficacy and Dose-Response Trial of Two Intravenous Doses of BMS-204352 in Patients with Acute Stroke. Robert J. Dempsey, M.D., (Regional) Principal Investigator, approved and funded, $128,460, Bristol-Meyers Squibb, 1999-2002. The Clomethiazole Acute Stroke Study in Ischemic Stroke. A Double-Blind, Parellel Group, Multinational, Multicenter Study of the Efficacy and Safety of I.V. Clomethiazole Compared to Placebo in Patients with Acute Ischemic Stroke. Douglas A. Dulli, M.D., (Local) Principal Investigator, Robert J. Dempsey, M.D., (Local) Sub-Investigator. Astra USA, Inc., 1999-2002. ADDITIONAL STUDIES OR COURSES Neurology Rotation at the University of London, Queen Square Hospital, London, England, from January 3, 1980, to February 26, 1980. Attended Review Course in Neuropathology. The Armed Forces Institute of Pathology, Washington, D.C., January, 1981 Attended Review Course in Neurological Surgery, Cook County Graduate School of Medicine, February, 1982
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 62 Midax Rex Surgical Institute, October, 1983 “Spinal Instrumentation in the Management of Thoracolumbar Fracture,” Southern Neurosurgical Society, March 14, 1984 Postgraduate Seminar, “Chemonucleolysis,” S.I.U. School of Medicine, May 12, 1984 “Neurosurgical Micro-operative Techniques and Microsurgical Instrumentation,” Southern Neurosurgical Society, February 26, 1986 Toronto Stroke Workshop, University of Toronto, September, 1986 “Recent Advances in Carotid Doppler,” September, 1986 2nd International Symposium and Tutorial on “Intracranial Hemodynamics: Transcranial Doppler and Cerebral Blood Flow,” February 1988 “Techniques for Intra-operative Localization of Lesions in the Brain,” Southern Neurosurgical Society, March 30, 1988 “Laser One International Symposium on Endovascular Laser Use,” May, 1989 “The International Symposium on Advances in Laser Surgery,” Cincinnati Laser Center, May, 1989 Advanced Trauma Life Support Instruction Course (20 hours), Amer. Coll. of Surgeons, June, 1989 “Intensive Care for the Neurosurgeon,” Southern Neurosurgical Society, March, 1990 “Methods and Tools of Quality Improvement,” Institute for Healthcare Improvement, March, 1992 Cerebral Hemodynamics Basic Tutorial on Transcranial Doppler and Advanced Tutorial on Cerebrovascular Monitoring, International Cerebral Hemodynamic Society, February, 1993 Focus on Health, Radio Program on Stroke Prevention, Madison, WI, March, 1996 “Brain Surgery Microscope,” Center for Health Sciences Video News, U. Wisconsin, October, 1996 “Reimbursement Update for Neurosurgeons,” American Assn. of Neurological Surgeons, Nov., 1996. “An Introduction to the ACGME and the Accreditation Process,” Accreditation Council for Graduate Medical Education, Chicago, March, 1997. “Anterior Skull Base Surgery,” Congress of Neurological Surgeons, New Orleans, September 1997. “MKM Training: IGS School,” Zeiss course, New York, November, 1997.
    • Robert J. Dempsey, M.D. Curriculum Vitae Page 63 “Research Update in Neurosciences for Neurosurgeons,” Woods Hole, MA, October 1999. "Assessing Clinical Skills and Quality," Council of Medical Specialty Societies, Spring Symposium 2000. “Neurovascular Centers of Excellence: A Blueprint for Development,” Chicago, November 2000. Last updated: September 2007