2. What Is Cancer ? Cancer is a disease of uncontrolled cell growth caused by exposure to carcinogens (cancer-causing substances), genetic defects, or viruses. Cancer cells can multiply and form a large mass of tissue called a tumor. Some tumors are limited to one location and can be surgically removed. These tumors may cause little harm and are therefore termed benign. Cancer cells of other tumors may spread, or metastasize (muh-TASS-tuh-size), to surrounding tissue or other organs of the body. Such aggressive tumors are termed malignant. Cancer is a word used usually to describe malignant, not benign, tumors. The study of cancer is called oncology. A transmission electron micorgraph of two spindle cell nuclei from a human sarcoma. Sarcomas are cancers of the connective tissue
4. What is Cancer Cell ? Cancer Cell is the first Cell Press journal to focus on a specific disease field, with an editorial scope spanning from basic to clinical-oriented researches and a strong emphasis on translational research. Cancer Cell provides a high-profile forum for showcasing advances in cancer research, from those elucidating significant advances in understanding the disease processes of cancer to those establishing new paradigms in the diagnosis, therapy, and prevention of cancers.
6. How Cancer Cells are Formed ? The transformation of a normal cell into a cancer cell can occur when the genetic material (deoxyribonucleic acid or DNA) of a cell is changed, or mutated. A tumor is the result of multiple gene mutations within a single cell. Years or decades before a tumor forms, a cell can become weakened by various factors, making it more susceptible to later transformation into a cancer cell. Cancer is often a disease of age, with many occurring after age fifty.
13. Properties of Cancer Cells Unlimited Replicative Potential Absence of Apoptosis Absence of Telomere Shortening Angiogenesis Metastasis
14. Cancer Prevention Research Nutritional Science Cellular and Molecular Biology Infectious Disease Surgery Public Health Policy Epidemiology Behavioral Medicine Imaging/ Screening Pharmacology
15. Cancer Prevention and Control The Cancer Prevention and Control Program has three broad research themes with specific objectives. These are Theme 1: Prevention Objective 1 - Alter behaviors that are related to development of cancers (smoking, unsafe sexual practices) Theme 2: Early Detection Objective 2 - Increase screening for breast and colorectal cancer and translate these findings to clinical practice Theme 3: Diagnosis and Survivorship Objective 3 – Identify and test interventions for symptoms experienced by cancer survivors and families.
