Development of nano-scale technologies for food safety protection

Improving Life through Science and Technology. Development of nano-scale technologies for food safety protection Matthew Taylor, Ph.D. Department of Animal Science, Texas AgriLife Research September 14, 2011

Nanotechnology Significance
“ Nanotechnology holds great promise for the development of new treatments and diagnostics.”
Andrew Von Eschenbach, MD
FDA Commissioner, 2007
FDA Nanotechnology Task Force Report, 2007

Global Nanotechnology Research Funding Adapted from Bugusu (2010). Food Technology (www.ift.org)

Nano-materials in Foods
Naturally occurring
Food macro-, micro-components & nutrients
DNA, RNA
Casein micelles
Synthetic systems
Encapsulates
Nano-wires
Biosensors

Nano-materials entry into foods Magnuson et al. 2011. J. Food Sci. 76:R126.

Food Safety Applications of Nanotechnology
Antimicrobial encapsulation/delivery strategies
Encapsulates
Nano-wires
Active packaging/antimicrobial-bearing films
Pathogen detection/diagnostics
Biosensors

Nanotechnologies: Regulatory Concerns
Definition of nano and engineered versus naturally occurring
Purpose(s) of engineered nanotechnology use in foods
Detection of nanomaterial presence in foods
Characterization of interactions with food components
Safety and toxicity of nanomaterials

Antimicrobial Encapsulations
Liposomes, Micelles
Self-directed formation
Entrapment rate can be high
Formed from lipids dispersed in aqueous systems
Not long-term stable without post-formation modifications

Liposomal Formulations Taylor et al. 2006. Crit. Rev. Food Sci. Nutr. 45:587.

L. monocytogenes Inhibition in Milk with Liposomal Nisin (50 IU/ml) at 20°C Schmidt et al. 2009. Probiotics Antimicrob. Prot. 1:152-8.

E. coli O157:H7 Inhibition in 2% Milk with 0.5% Eugenol Microemulsions Gaysinsky et al. 2007. J. Food Protect . 70: 2631-7. Assay Detection Limit

Polymeric Encapsulate Research
Β -Cyclodextrins
Antimicrobials (Essential Oils)
Carvacrol
Thymol

Texas A&M Nanotechnology Research in Food Safety
Dairy (Fluid Milk): Liposomes with entrapped nisin inhibit Listeria monocytogenes (Schmidt et al. 2009)
Fresh Produce (Pre-, Post-Harvest)
Micellar organic acids, essential oils
Field application, packing house
Pathogen inhibition
USDA Funding: NIFSI, AFRI
Processed/RTE poultry: Incorporated pre-lethality for L. monocytogenes control post-processing
Corporately sponsored
Validation of antimicrobial activity

Forced nano-particle/pathogen interaction on produce surfaces

Collaborators (TAMU)
Investigators:
Elsa Murano
Alex Castillo
Luis Cisneros-Zevallos
Carmen Gomes
Christine Alvarado
Graduates:
Laura Hill (PhD)
Keila Perez (PhD)
Songsirin Ruengvisesh (PhD)
Shannon Schmidt (MS)

T. Matthew Taylor, PhD
310 Kleberg Animal and Food Sciences Center, College Station, TX, 77843-2471
P: 979.862.7678; F: 979.862.3475
Email: matt_taylor@tamu.edu
http://animalscience.tamu.edu/facultystaff/faculty/taylor.htm

Thank you!

Development of nano-scale technologies for food safety protection

by dedmark on Sep 19, 2011

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Development of nano-scale technologies for food safety protection — Presentation Transcript