Church apr2013
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Church apr2013

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Talk to high school students visiting NIH.

Talk to high school students visiting NIH.

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  • What exactly do we mean by ‘The Human Genome’
  • This is a picture of one person’s genome

Church apr2013 Church apr2013 Presentation Transcript

  • Human Genomes
  • The Human Genome Project
  • Figure 1. Identification of recombination events.Chowdhury R, Bois PRJ, Feingold E, Sherman SL, et al. (2009) Genetic Analysis of Variation in Human Meiotic Recombination. PLoS Genet 5(9):e1000648. doi:10.1371/journal.pgen.1000648http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000648
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  • Figure 1. Sequence Structure of Structural Variant and Genotyping Assay DesignKidd JM, Newman TL, Tuzun E, Kaul R, et al. (2007) Population Stratification of a Common APOBEC Gene Deletion Polymorphism. PLoS Genet3(4): e63. doi:10.1371/journal.pgen.0030063http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030063
  • ClonesClonesIHGSC, Nature 2004
  • RP11-34P13 64E8 RP4-669L17 RP5-857K21 RP11-206L10 RP11-54O7Gaps
  • http://theamazingios6maps.tumblr.com/
  • Preview of GRCh38 (scheduled Fall 2013)TEX28 TKTL1LOC101060233(opsin related)LOC101060234(TEX28 related)GRCh37 (current reference assembly)chrX
  • 23andMe
  • NOT
  • Matsunaga (1962)