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Healthcare 2020: Intelligent Medicine
                March, 2010
Issues and Opportunities in the Pharmaceutical Industry


                                    Issues                      ...
Proteus Snapshot

                                            Company Overview
     Founded in 2001
     Total of $115 mil...
Proteus Approach: The “Networked Pill”


     Incorporate sensors into existing drugs; measure therapy delivery and its ef...
Raisin Intelligent Pharmaceutical System




5
Networking the Daily Pills You Already Take


         Proteus Ingestible Event Marker (IEM)
                             ...
Monitoring via a Band-Aid Familiar to Consumers




                                              •   Wearable sensing dev...
Information Delivered to the Cell Phone In Your Pocket




8
Summary: Raisin Enables Truly Personal Personalized Medicine


    • Combines behavioral and physiologic data at individua...
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Proteus Overview

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Transcript of "Proteus Overview"

  1. 1. Healthcare 2020: Intelligent Medicine March, 2010
  2. 2. Issues and Opportunities in the Pharmaceutical Industry Issues Opportunities • Do I get a benefit? • I see my therapy helping Patient • I know I get side effects • I am more in control • Is it worth it? • I am rewarded for success • What are the right drugs and doses? • Patient-specific therapy Physician • Little time, too much to diagnose • Efficient, positive office visits • Is it worth it? • Focus on the right patients and issues • Is the branded drug necessary? • Objective measurement of benefit Payer • Most drugs don’t work over time • Post-market risk assessment • Is it worth it? • Empowered members are happy/quiet Overall • Dubious value, lack of trust, no • Measured value, aligned goals, enduring sustainable product loyalty connection to product system 2
  3. 3. Proteus Snapshot Company Overview Founded in 2001 Total of $115 million in financing (Carlyle, EWHV, Kaiser Permanente, Medtronic, St. Jude, Itochu, Novartis, ON Semiconductor, others) Unique organization Novel integrated circuit, MEMS and sensor design for custom medical applications Signal processing and software development for intra-body communication Product design, development and manufacturing from bench to clinical investigation Physician and Nurse Remote Strategic partnerships with global pharmaceutical and medical devices companies Connectivity 300+ patent filings Patient 3 programs in clinical trials Personal Support Group Medical Connectivity Named a Technology Pioneer by the World Economic Forum and a Top 10 Technology Records Breakthrough in 2008 by Wired Magazine First product launch 2012 3
  4. 4. Proteus Approach: The “Networked Pill” Incorporate sensors into existing drugs; measure therapy delivery and its effect on individual patients Use this information, wellness tools and communication technologies to improve patient care and outcomes Increase productivity of clinical caregivers Include and acknowledge the family caregiver Empower patients and treat them like consumers Build on existing reimbursement driven revenue models Deliver greater medico-economic value to support reimbursement model Build direct connection to family and consumer to support subscription model Leverage network effects to maximize overall franchise revenue potential 4
  5. 5. Raisin Intelligent Pharmaceutical System 5
  6. 6. Networking the Daily Pills You Already Take Proteus Ingestible Event Marker (IEM) • Single < 1mm chip • Senses and signals unique identifier when swallowed • Accurate: >97% detection in human clinical trials • Safe: made from ingredients in food • Cheap: 250,000 produced on $1,000 wafer • Private: EKG-like signal conducted only in body Enables Device-Based Sensing and Monitoring of Pharmaceuticals 6
  7. 7. Monitoring via a Band-Aid Familiar to Consumers • Wearable sensing device − Sensors for intelligent pharmaceuticals − Sensors for physiological response • Sensing of drug ingestion, HR, respiration, physical activity and body angle Enables Continuous Correlation of Therapeutic Event and Response 7
  8. 8. Information Delivered to the Cell Phone In Your Pocket 8
  9. 9. Summary: Raisin Enables Truly Personal Personalized Medicine • Combines behavioral and physiologic data at individual patient level • Customizable and collaborative care tool to affect behavior change • Compatible with other disease management devices • Consistent with global business and social trends • Anywhere, anytime mobile connectivity • Personal healthcare responsibility • Social networking and online health communities 9
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