Xopenex
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Xopenex

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Xopenex Xopenex Presentation Transcript

  • Xopenexlevalbuterol
    By Danielle Gill
    UC PharmD Candidate
    Plateau Medical Center
  • Beta-2 agonist
    R-isomer of albuterol
    Fast-acting
    Used for the prevention of bronchiospasm
    Asthma and Chronic Obstructive Pulmonary Disease (COPD)
    Pharmacologic Category
  • Coughing
    Sneezing
    Chest tightening
    Shortness of breath
    Relaxes Tightened muscles around the airway
    Symptom relief
  • XOPENEX Inhalation Solution (nebulizer)
    ages 6-11: 0.31 mg up to 0.63 mg TID
    12 or over: 0.63-1.25 mg TID
    This form is turns the medicine into a vapor like mist so it can be inhaled by the patient.
    Dosage
  • Tachycardia
    Increase in blood pressure
    Dyspepsia
    Leg cramps
    Dizziness
    Tremor
    Adverse Effects
  • heart disease (e.g., reduced heart circulation, high blood pressure, and irregular heartbeat)
    seizures
    high levels of thyroid hormone
    diabetes
    Precautions for patients
  • Store XOPENEX in the protective foil pouch at room temperature (68°F - 77°F).
    Protect from light and excessive heat. Keep unopened vials in the foil pouch.
    Once the pouch is opened, the vials should be used within two weeks.
    Vials removed from the pouch, if not used immediately, should be protected from light and used within one week.
    Discard any vial that is opaque
    Storage requirements
  • Albuterol is equivalent in effectiveness to Xopenex and it costs more ($0.42 vs. $5.61/day)
    Xopenex was shown to cause greater changes in heart rate and blood sugar then Albuterol
    Pharmacy is looking into discontinuing this drug on their formulary.
    Possible Problems
  • Orzali Peter. Xopenex. Pharmacy Proposal for Formulary Removal.
    Xopenex website available at www.xopenex.com
    Lexi-Comp. University of Charleston School of Pharmacy. Online.
    References