Micronutrients

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Micronutrients

  1. 1. Micronutrients - Vittal
  2. 2. CHOOSE YOUR TRACE METAL IRON IODINE COPPER ZINC COBALT CHROMIUM SELENIUM COPPER MANGANESE MOLYBDINUM NICKLE VANADIUM IRON IODINE COPPER ZINC COBALT CHROMIUM SELENIUM COPPER MANGANESE MOLYBDINUM NICKLE VANADIUM
  3. 3. IRON SOURCE FUNCTION DEFICIENCY Fish, Liver, meat, jaggary, Meat group, Leafy Greens, cereals, legumes, dates, turmeric, watermelon Constituent of Hb., enzymes, role in O2 transport LBW, Blood loss, hook worm, malabsorption , poor intake
  4. 4. IRON Clnical Features Requirement Remarks Pallor, dyspnoea, CCF, irritability, lack of conc.,pica, koilonychia, Prophylaxis: 2 mg/kg/d Treatment: 6 mg/kg/d O for 3-4 mo. Oxalates, Zn, phytates inhibit absorption Toxicity: GI Upset, metabolic derangement, acidosis, hepatic failure. Tt. : Gastric lavage, Desferoxamine, Deferiprone
  5. 5. IODINE SOURCE FUNCTION DEFICIENCY Sea foods, drinking water, iodized salt Constituent of thyroxine Low content in water, excessive intake of cabbbage, cauliflower
  6. 6. IODINE Clnical Features Requirement Remarks Goitre, hypothyroidism, still birth, CNS defect Investigations: Urinary iodine, PBI, T3, T4, TSH, Iodine uptake 50-150 mcg/day Iodized salt to contain 15 mcg/g (15 ppm) uptp 30 ppm is added t tackle loss Toxicity: Goitre
  7. 7. COPPER SOURCE FUNCTION DEFICIENCY Liver, fish, meat, oyster, legumes, Constituent of enzymes, ceruloplasmin role in hemopoisis, bone metabolism LBW, preterm, TPN, PEM, Nephrotic syndrome
  8. 8. COPPER Clnical Features Requirement Remarks Liver, fish, meat, oyster, legumes, nuts, prunes Constituent of enzymes, ceruloplasmin role in hemopoisis, bone and connective tissue metabolism, nerve fibres and skin Hypochromic anemia, neutropenia, hypopigmentatio n of hair, bony defects Inv: S.Cu: 75- 150 mcg% S.Cerulo: 10-15 mcg%
  9. 9. ZINC SOURCE FUNCTION DEFICIENCY Liver, beef, oyster, wheat germ, nuts, grapes. Phytates reduce absorption Constituent of enzymes, ceruloplasmin role in protein and nucleic acid synthesis PEM, hepatitis, TPN, nephrotic syndrome, acrodermatitis eneteropathica
  10. 10. ZINC Clnical Features Requirement Remarks Growth retardation, anroexia, gonadal atrophy, alopecia, diarrhoea, reduced taste sensation Inv.: S.Zn: (60 – 150 mcg%), Hair Zn. 5 -15 g / d Treatment: 1-2 mg / kg / d Used as adjuvant in Tt. Of Wilson;s Disease, Diarrhoeal disorders Toxicity: GI Upset, Cu deficiency
  11. 11. COBALT SOURCE FUNCTION DEFICIENCY Meat group Constituent of B12, role in iron absorption, iodine utilization PEM, TPN
  12. 12. COBALT Clnical Features Requirement Remarks Hypothyroidism, anemia, goitre, Inv. : S.Co. (0.007 mcg%) Not known Excess can cause goitre and cardiomyopathy
  13. 13. CHROMIUM SOURCE FUNCTION DEFICIENCY Yeast, liver, cereals, nuts, cocoa, pepper, cheese, chickens, mushrooms, molasses Facilitates insulin action PEM, TPN
  14. 14. CHROMIUM Clnical Features Requirement Remarks Hyperglycemia, encephalopathy Inv. : S.Cr. (0.02 mcg%) 10 mcg/d Treatment: 180 mcg single dose Renal failure, dermatitis
  15. 15. MOLYBDINUM SOURCE FUNCTION DEFICIENCY Legumes, whole grains, greens, meat group, nuts Components of xanthine oxidase, instrumental in iron storage. Instrumental in production of uric acid. TPN, poor soil content
  16. 16. MOLYBDINUM Clnical Features Requirement Remarks Mouth and esophageal cancers, tachycardia, coma Inv. : S.Mo. (0.07 mcg%) 250-500 mcg/d Bony defects, hyperurecemia, competes with Cu absorption. Deficiency never occurs
  17. 17. SELENIUM SOURCE FUNCTION DEFICIENCY Meat group, greens, garlic, oysters Antioxidant co- factor, maintains liver integrity PEM, TPN, poor soil content
  18. 18. SELENIUM Clnical Features Requirem ent Remarks Keshan cartiomyopathy, arthritis, myalgia, growth retardation, liver necrosis, risk of cancer , Kashin-Beck Disease (chondrodystrophy) Inv. : S.Se. (13 mcg %) 100 mcg/d Dental caries, alopecia, garlic odour in breath
  19. 19. MANGANESE SOURCE FUNCTION DEFICIENCY Cereals, nuts, legumes, whole grains, egg yolk, greens, tea Component of superoxide dismutase, role in oxidative phosphorylation, bone and tendon formation TPN
  20. 20. MANGANESE Clnical Features Requirement Remarks Growth retardation, reddening of hair, increased prothrombin time Inv. S. Mn. (0.06 mcg) 1-5 mg / d Encephalitis, goitre, cardiomyopath, cholestasis. Iron decreases absorption of Mn
  21. 21. NICKLE SOURCE FUNCTION DEFICIENCY Chacolates Component of urease, nickle, plasmin, stabilizes membranes TPN
  22. 22. NICKLE Clnical Features Requirement Remarks Inv. S. Ni. (0.02 mcg) Not known Dermatitis, linver, necrosis, nasal and lung cancers
  23. 23. SILICON SOURCE FUNCTION DEFICIENCY Cross linkage of collagen TPN
  24. 24. SILICON Clnical Features Requirement Remarks Growth retardation, defective bone growth Not known Glaucoma and fibrosis of lung
  25. 25. VANADIUM SOURCE FUNCTION DEFICIENCY Protein rich food TPN PEM
  26. 26. VANADIUM Clnical Features Requirement Remarks Associated with nutritional edema Not known

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