Rob Scoffin, Cresset, 'The Cresset Future'
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  • 1. The Future of Cresset?
    Dr Robert Scoffin
    Chief Executive Officer
  • 2. Customer Thanks
    You are the reason we are here
    Our motivation is to create the best possible tools to aid drug discovery
    Your input drives future developments
    Your financial support enables us to keep the lights on
    You are also the reason we will be here next year
    Our ongoing commitment to maintaining the high quality of our solutions
    Focus on innovation in both science and service
    Returning value for your investment in us
  • 3. 2010-2011 Year In Review
    Cresset
    Business grew 25% from 2009 to 2010
    Continued growth in 2011 – projecting > 35% 2010 to 2011
    Strong additions to the team – Mike, Rae, Viv, Janany, Chris, Martin, Rachel.
    Science
    Extension of FieldAlign with 3D-QSAR methodology
    On-going development of new application for ‘Molecular Designers’
    Extended applications in peptide mimetics, drug re-profiling, etc.
    Portfolio Expansion
    Extended Professional Services/Consulting offerings – driven by Martin Slater, backed up by Chris Earnshaw, Andy, Rob, Tim & Mark
    Software-as-a-Service (SaaS) offering of FieldScreen (initially – others to follow)
  • 4. Diverse Cresset Users
    Medicinal Chemists
    Molecular Modellers
  • 5. Strategy for Growth
    Consolidate our position in existing markets
    Strengthen current tools
    Look for other applications we can build on the existing science
    Further expand the science base of Cresset
    Develop New Markets
    Med. Chem focus through new applications
    New users for existing technology: Patenting, In-Licencing, ADMET, etc.
    Expanded Services Offerings
    Consulting services around use of the applications
    New delivery platforms for existing applications
  • 6. New delivery platforms
    The latest addition to the Cresset team
    The Cresset cow
    Cluster On Wheels
    Portable, on-demand computing infrastructure
    Pre-loaded FieldScreen application and database
    Plug-in and go capacity expansion
    Secure – data on portable, removable drives
    The Cresset COW
  • 7. Scientific Focus
    FF3
    Free Dr Vinter up from mundane day-to-day activities to focus on completing FF3
    Extensive validation and testing cycle – aim to release in 2012
    Re-Profiling/Re-Purposing
    Extend applications in drug re-profiling
    TSB funded project with Biolauncher to build re-profiling database and toolkits
    Massively parallel computing
    New initiative to re-code Cresset tools (initially FieldScreen, others to follow) to run on GPU’s
    OpenCL implementation of the scoring functions
    Fields/Field points on proteins
    Further investigation and application of Field approach to protein surfaces and structures
  • 8. May the Force (field) be with you…
    There’s a disturbance in the Nitrogen force
    When will FF3 be ready?
  • 9. Scientific Focus
    FF3
    Free Dr Vinter up from mundane day-to-day activities to focus on completing FF3
    Extensive validation and testing cycle – aim to release in 2012
    Re-Profiling/Re-Purposing
    Extend applications in drug re-profiling
    TSB funded project with Biolauncher to build re-profiling database and toolkits
    Massively parallel computing
    New initiative to re-code Cresset tools (initially FieldScreen, others to follow) to run on GPU’s
    OpenCL implementation of the scoring functions
    Fields/Field points on proteins
    Further investigation and application of Field approach to protein surfaces and structures
  • 10. Ridley Scott’s Tribute to Andy
    Tyrell: The light that burns twice as bright burns for half as long - and you have burned so very, very brightly, Roy Andy. Look at you: you're the Prodigal Son; you're quite a prize! 
    Batty: I've done... questionable things. 
    Tyrell: Also extraordinary things; revel in your time. 
    Andy Vinter
    Batty: Nothing the God of biomechanicsdrug discovery wouldn't let you into heaven for. 
  • 11. rob@cresset-group.com
    Questions welcomed