PURITY (HPLC) 99.95% or Higher
http://www.mybodybuildingcoupons.com
Creatine Monohydrate has been used for years by millions of athletes as a safe and
effective method of increasing endurance while diminishing the time it takes the body to recover.
The body produces certain levels of creatine naturally. As these stores are used up, fatigue and
lactic acid buildup sets in. By augmenting the body's own production with a creatine supplement,
additional creatine becomes available to muscle cells helping to increase power, endurance and
muscle size by means of cell volumizing.
Athletic potential is determined in part by two very significant factors, power and endurance. By
increasing these two factors, an athlete can look forward to greater ability and achievement.
While many supplements have been introduced with the promise of delivering increased athletic
performance, actual results were never realized.
In 1922, research published in the British medical journal "Clinical Science" cited remarkable
benefits obtained from a new supplement administered to athletes. The supplement was Creatine
Monohydrate and the results from the research would create a new path for athletes to follow to
attain greater physical conditioning.
What is Creatine Monohydrate?
The body actually produces its own store of Creatine. The amino acids Arginine and Glycine are
synthesized into Creatine by the liver and kidneys. 95% of the Creatine produced is transported
to muscle cells where it is use in manufacturing the energy-producing molecule Adenosine
Triphosphate (ATP). The levels of Creatine available to muscle fiber determines the amount of
ATP produced. When Creatine stores in the body are depleted from physical exertion, the level of
ATP diminishes causing muscle fatigue and increased levels of lactic acid.
By supplementing the diet with Creatine Monohydrate, the body's store of Creatine is increased
along with the production of ATP. Ingested Creatine Monohydrate enters the bloodstream making
its way to the cells of muscle tissue. Sufficient intake literally "saturates" the muscles with
Creatine providing increased strength and faster recovery time from intense physical training.
The benefits of taking Creatine Monohydrate can be seen quickly, often within a few days.
Athletes can expect a marked improvement in power and endurance from the addition of the
amazing compound. For example, an athlete involved in weight training may find the number of
repetitions at a given weight increase in number.
In addition, Creatine Monohydrate can help increase muscle size. The cells of muscle tissue are
made of approximately 70% water. When the muscle cells absorb Creatine, they also take in
water. This process, called "Cell Volumizing" or "Cellular Hydration," allows the muscle to
increase in mass. During cell volumizing, the water is stored in the muscle cell and is not to be
confused with water retention where water is stored outside the cells. Sci entific research
supports the theory that as cell volumizing is increased, the rate of protein metabolism is also
increased leading to faster muscular development.
Using only American made raw material, Vitalabs Creatine Monohydrate is guaranteed to be of
the highest quality possible. Every batch is certified by independent laboratory analysis and must
meet the following specifications:
Creatine
Monohydrate:
99.95%
PURITY (HPLC) or
Higher

CREATININE 0.01%
HEAVY METAL CONTENT
BQL@PQL of 0.1 PPM
Less
DICYANDIAMIDE than
0.1%
Less
CYCLOCREATINE than
0.1%
Supplement Facts
Serving Size: 5 grams (2 scoops)
Servings Per Container: 60
Amount Per Serving % Daily Value
Creatine Monohydrate 5,000 mg *
*% Daily Value not established
Ingredients: Creatine Monohydrate powder guaranteed to be a
minimum of 99% pure
Suggested Use
• As a dietary supplement, take five grams (2 scoops) 30 to 45 minutes before and /or after
training with 8-12 ounces of juice or high carbohydrate beverage.
• It may be advisable take this product in cycles: 4 to 6 weeks on, then 4 to 6 weeks off.
• Do not exceed 10 grams per day
Caution
• Maintain sufficient fluid intake while taking this product.
The “Strength Supplement” that Improves Brain Power
By Dr. Edward R. Rosick
Some in mainstream medicine believe that anti-aging researchers and physicians are a
hedonistic lot, interested only in preserving their young and supple physiques at any cost. In my
experience, however, nothing could be further from the truth. I find that a vast majority of anti-
aging physicians are proponents not only of keeping their patients looking and feeling their best,
but also of keeping their minds sharp and their memories intact.

For those interested in maintaining a sharp mind and a supple figure, creatine is a must-take
supplement. Many know creatine only as a popular supplement used by athletes, bodybuilders,
and other fitness enthusiasts to maintain muscle mass and improve exercise performance. But
exciting new scientific evidence shows that creatine not only can help people with degenerative
neurological disorders, but also may help just about everyone maintain a healthy, clear-thinking
mind.
Keeping Muscles Strong and Healthy
Creatine, a compound comprising the amino acids methionine, glycine, and arginine, was
discovered and isolated from meat extract in 1835. Humans produce creatine in the kidney, liver,
and pancreas, but store most of it in muscles, including the heart. While creatine has been known
since the early 1800s, not until the end of the 20th century did scientists discover that when taken
as a supplement, creatine can be of significant help in adding muscle mass.
More than 500 well-researched studies have been conducted showing that creatine supplements
can help everyone—men and women, young and old—maintain muscular fitness and ward off
some of the most debilitating effects of aging, such as sarcopenia, the age-related loss of muscle
mass and strength. A study published in February 2003 examined the effect of 250 supplements
on lean muscle mass and strength gains with resistance exercise. Of all the supplements,
creatine was one of the few that consistently augmented lean muscle mass and strength in both
the young and old.1 Another study published in 2003, which reviewed over 300 studies on the
potential ergonomic value of creatine supplementation, concluded: “the preponderance of
scientific evidence indicates that creatine supplementation appears to be a generally effective
nutritional ergonomic aid for a variety of exercise tasks in a number ”2
Essential for Maintaining Energy
Creatine increases exercise capacity and muscle mass through its role in regenerating adenosine
triphosphate, or ATP. ATP is the body’s primary “energy molecule” and is used in cells as energy.
A useful analogy is to think of ATP as the body’s natural fuel in the same way natural gas is
burned in a modern power plant to produce electricity. In the body, ATP is broken down, or
“burned,” to produce biochemical energy. During this biochemical process, ATP loses one of its
phosphate molecules and is changed to adenosine diphosphate, or ADP, and it is here that
creatine becomes so vitally important. Creatine, which is stored in the body as creatine
phosphate, or phosphocreatine, recharges ADP by giving up, or donating, a phosphate molecule
to ADP, which produces more ATP that can then be used to make more energy. Without creatine
to recharge ATP, we literally would be “starved” for energy.
The Brain’s Thirst for Energy
The next time you watch a football game, take a close look at one of the larger players on the
offensive or defensive lines. Then try to imagine what part of his body consumes the most
energy. Is it his tree-like arms? His barrel-sized chest? Or is it his massive legs, which have to
carry that 350-pound frame all over the playing field?
The surprising answer is none of the above. The part of the human body that needs the most
energy is the small, three-pound mass of gray matter residing in the skull—the brain. While the
human brain makes up only 1-3% of a person’s total body weight, its billions of neurons (the
brain’s active nerve cells) use 15-20% of the body’s total ATP-derived energy.
Energy derived from ATP is used by the brain for neuronal repair, to produce, package, and
secrete neurotransmitters, and to power the bioelectrical discharges that occur when neurons
communicate with one another. This bioelectrical process, which is active every second of every
day, occurs via the rapid, continuous exchange of sodium and potassium ions across neuronal
membranes, a process that depends on biochemical “pumps” inside the membrane to move the

sodium and potassium ions back and forth. It has been estimated that as much as 45% of a
neuron’s ATP may be used to power these all-important sodium-potassium pumps.
Creatine and Neurodegenerative Disorders
When you realize how important ATP and thus creatine is to brain function, it should come as no
surprise that certain genetic disorders characterized by inborn errors in brain creatine metabolism
can cause significant neurological defects. The first inborn error of brain creatine metabolism,
GAMT (guanidinoacetate methyltransferase) deficiency, was clinically described in 1994.3
GMAT deficiency is an autosomal recessive disorder in which creatine levels in the brain are
almost undetectable. This genetic deficiency manifests early in life as developmental delay,
mental retardation, speech disabilities, and muscular weakness. Studies have shown that oral
creatine supplementation by patients with this disorder can help slow or even reverse some of its
most debilitating symptoms. AGAT (arginine: glycine amidinotransferase) deficiency is another
autosomal genetic disorder in which minimal or no creatine metabolism in the brain results in
mental retardation, language disorders, and poor fine motor skills.3 In a study of two sisters aged
four and six years with AGAT deficiency, creatine supplementation caused rapid progress in fine
motor skills and an increase in general cognitive development.
Three Deadly Neurological Diseases
Recent studies have shown that creatine can help not only in genetic disorders of creatine
metabolism but also in nongenetic disorders of the central nervous system. It is now postulated
by many brain researchers that dev-astating neurological disorders such as Parkinson’s,
Huntington’s, and Alzheimer’s diseases share fundamental biochemical processes in their
pathogenesis, such as oxidative stress and the impairment of creatine-powered ATP energy
metabolism. To support this theory, varieties of animal models and, in some cases, human
studies have shown that creatine supplementation can significantly ameliorate various common
symptoms of many neurological diseases. It is believed that creatine may accomplish this by
acting as a “booster” to the ATP energy system and also as a direct antioxidant.4
Parkinson’s is a chronic neurological disease that was first described in 1817 by Dr. James
Parkinson, a London physician. Since that time, some limited medical therapies have been
developed to treat this progressive disease, yet scientists still do not know what causes Park-
inson’s disease. What is known is that neurons in the area of the brain known as the substania
nigra degenerate and die, causing reduced levels of dopamine, a vital brain neurochemical.
Common symptoms of Park-inson’s include resting tremors, rigidity, balance problems, and
depression.
While scientists continue to search for the cause of Park-inson’s, some medical researchers are
postulating that impairment of the ATP energy-generated system and oxidative damage to
neurons may play key roles in the pathogenesis of this disease affecting 1.5 million Americans.5
Supplements such as creatine, which can help boost ATP levels and work as antioxidants, are
being examined as possibly safe and effective fighters of Parkinson’s disease. Recent animal
studies are quite promising and show that creatine supplementation can protect against both the
dopamine depletion and neuronal loss seen in Parkinson’s.5,6 While no human studies have
been published, it makes sense to think that supplements such as creatine, which can act as a
potent brain antioxidant and boost ATP function, may prove to be valuable tools in combating
Parkinson’s.
Creatine supplementation also may prove to be a valuable weapon in the fight against
Huntington’s disease. This devastating, irreversible neurological and genetic disorder affects a
quarter of a million Americans and robs them of the ability to walk, think, talk and reason. At
present, no effective cure exists for Huntington’s disease. Yet here again, creatine
supplementation may prove to be useful in ameliorating some of the disease’s most debilitating

effects. A 1998 study found creatine supplementation offered significant protection against
Huntington’s-like brain damage in rats.7 The study’s authors concluded, “oral administration of
either creatine or cyclocreatine can buffer cellular ATP concentrations and can attenuate cell
death in animal models that mimic the neuropathological and clinical phenotype of Huntington’s
disease.” More good news emerged from a study published in July 2003 that examined the
effects of 10 grams a day of creatine on patients with Huntington’s disease.8 After one year,
patients who took supplemental creatine showed no measurable change in their mental condition,
a sign that creatine was able to stop the neurological degeneration associated with Huntington’s
disease.
Some researchers believe that creatine may even be useful in combating the debilitating mental
effects of Alzheimer’s disease. In cultured rat neurons, creatine has been shown to prevent the
toxic effects of b-amyloid, a significant component of Alzheimer’s disease. With this in mind, the
authors of a recent study that examined elderly patients who have the ApoE genotype (known to
be a genetic risk factor for Alzheimer’s) stated: “… the potentially therapeutic effects of creatine in
cognitive impairment and AD [Alzheimer’s disease] might merit further inquiry and should perhaps
best not be overlooked.”9
Keeping Mind and Memory Strong
While creatine may prove useful in combating some of our most debilitating neurological
diseases, recently published research highlights how creatine can help people without
neurological disorders maintain optimal brain function and even improve memory.
Several well-researched studies have conclusively demonstrated that brain creatine levels are
tied to optimal memory ability and retention. One study published in 2000 examined working
memory ability—defined as the brain’s capacity to “hold” information for future use without the
use of external cues—in children using magnetic resonance spectroscopy to measure various
brain neurochemicals.10 The researchers found that children with the highest levels of creatine
had the most robust working memory, and concluded: “… we speculate that higher resting
creatine levels may allow for greater in-task activation [and] facilitate processing.”
Brain creatine levels also have been found to correlate with memory ability in older adults. A
study published in February 2003 examined via magnetic resonance spectroscopy changes in the
brain in 20 older adults (average age of 70) during memory training tasks.11 The researchers
found that brain creatine levels rose during memory training. Another article published recently in
Neuroscience Research examined the effects of supplemental creatine on mental fatigue in 24
adult men and women.12 In this double-blind, placebo-controlled trial, subjects who took 8 grams
of creatine daily over a five-day period showed significantly less mental fatigue while performing
simple mathematical calculations compared to the subjects who did not take creatine. The
authors noted that while they did not know the specific mechanism of action, creatine appeared to
help increase oxygen utilization in the brain.