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Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
Bioinformatics with HPC Midlands
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Bioinformatics with HPC Midlands

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  • 1. Bioinformatics with HPC Midlands Martin Hamilton, Centre Manager
  • 2. Themes 1. The Landscape 2. HPC Midlands 3. What’s in Scope? 4. Next Steps
  • 3. Themes 1. The Landscape 2. HPC Midlands 3. What’s in Scope? 4. Next Steps
  • 4. The Landscape
  • 5. The Landscape
  • 6. The Landscape
  • 7. Themes 1. The Landscape 2. HPC Midlands 3. What’s in Scope? 4. Next Steps
  • 8. HPC Midlands – hpc-midlands.ac.uk – Centre of Excellence in High Performance Computing • £1m seed funding from EPSRC/BIS – Remit is to make Supercomputing Accessible to Industry • Working with startups and leading firms such as Airbus, E.ON, Rolls-Royce, RWE npower and Tata Steel • Flexible licensing from ISVs including ANSYS, CD-adapco and MSC Software
  • 9. HPC Midlands
  • 10. HPC Midlands
  • 11. HPC Midlands
  • 12. HPC Midlands 3,000 cores (48 Teraflops) 11 chassis (18 blades each) 15TB RAM 120TB Lustre storage Non-blocking QDR Infiniband 188 compute node blades: 2 x 2.0GHz (8 core) Sandy Bridge 140 with 64GB RAM (4GB/core) 48 with 128GB RAM (8GB/core)
  • 13. HPC Midlands
  • 14. Themes 1. The Landscape 2. HPC Midlands 3. What’s in Scope? 4. Next Steps
  • 15. What’s in Scope? – Bias towards industrially linked R&D work – Majority of use to date has been science and engineering – Interest from biotech sector – Links to big pharma and startups/spinouts
  • 16. Themes 1. The Landscape 2. HPC Midlands 3. What’s in Scope? 4. Next Steps
  • 17. Next Steps
  • 18. Next Steps – Use cases • “Conventional” MPI codes and off-the-shelf parallel apps • High Throughput Computing / embarassingly parallel codes – Bioinformatics applications • BLAST/CS-BLAST/CSIBLAST, Bowtie, Cufflinks, FAST A, GATK, … • HPC plugin for i2b2?
  • 19. Next Steps
  • 20. Next Steps – Collaborators sought! – Local or remote i2b2 database? • NHS infosec requirements • Redaction/anonymization/consent – Combining sources, e.g. Mosaic • Machine Learning • Big Innovation Centre: “Data Switzerland” etc – New or existing project?
  • 21. Bioinformatics with HPC Midlands Martin Hamilton, Centre Manager

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