A. DefinitionA genetic blooddisorder caused by thepresence of anabnormal form ofhemoglobin. Thesehemoglobin moleculestend to aggregate afterunloading oxygenforming long, rod-likestrictures that forcethe red cells to assumea sickle shape.
Signs & Symptoms Fatigue (tiredness) pale skin nail beds Jaundice shortness of breath Sudden episode of pain throughout the body.
Oral Manifestation An increased risk for periodontitis, or gum disease Abnormally pale tissue in mouth Glossitis
GLOSSITISPALE GUMS PERIODONTITIS
Oral Care SCD patients must undergo a thorough oral and dental examination, using appropriate radiographs. Proper hygiene. Strict dental appointments. Extractions should be done atraumatically
Classification of Sickle CellAnemia as a disease: •Mendelian- autosomal recessive genetic disease •Cytogenetics- The HBB gene is found in region 15.5 on the short (p) arm of human chromosome 11.