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Lesson 5 the role of the neuron in memory formation 2012 sh

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  • 1. Lesson 5 - The role of Neurons in Memory formationFriday, 13 April 2012
  • 2. Last lesson...... From which form of declarative memory is retrieval of information often more difficult? Why? 3 marksFriday, 13 April 2012
  • 3. Last lesson...... From which form of declarative memory is retrieval of information often more difficult? Why? 3 marks Answer Retrieval of information is often more difficult from episodic memory.There memories are less well learned, and are more context dependent and state-dependent in nature.Friday, 13 April 2012
  • 4. Todays lesson............ •Review the function of a neuron •Explain the role of the neuron in memory formation informed by the work of E. Richard Kandel!Friday, 13 April 2012
  • 5. Revision - The NeuronFriday, 13 April 2012
  • 6. Kandel found that any experience resulting in memory produces physical changes in the brain at the neuronal level, changes in structure and function of neurons.Friday, 13 April 2012
  • 7. Kandel’s Research on the role of neurons Eric Kandel studies the sea slug Aplysia for the following reasons: •Very simple nervous system •Only 20,000 neurons •Largest neurons in the world and can be seen with the naked eyeFriday, 13 April 2012
  • 8. Kandel’s experiments Studied simple learning and remembering of the gill- withdrawal reflex of Aplysia Observed changes at the synapse (i.e. point of communication by adjacent neurons) in the structure and function of neurons in three ways: •Release extra neurotransmitter •Increase number of receptor sites •Growth of new synapses These changes are called collectively Long Term PotentiationFriday, 13 April 2012
  • 9. Long Term PotentiationFriday, 13 April 2012
  • 10. Friday, 13 April 2012
  • 11. Friday, 13 April 2012