H1 N1 And Your Immunity

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H1 N1 And Your Immunity

  1. 1. H1N1 AND YOUR IMMUNITY Carol Morley, Naturopathic Doctor Zawada Health, Mississauga
  2. 2. Overview <ul><li>What is H1N1? </li></ul><ul><li>What is the history? </li></ul><ul><li>Transmission, progression and symptoms </li></ul><ul><li>Guidelines </li></ul><ul><ul><li>Health Canada, Ministry of Health, CDC, Motherisk </li></ul></ul><ul><li>Prevention </li></ul>
  3. 3. H1N1 <ul><li>Flu virus – human swine influenza </li></ul><ul><ul><li>Subtype influenza A </li></ul></ul><ul><ul><li>Genetic elements from four different flu viruses – North American swine influenza, North American avian influenza, human influenza, and swine influenza virus typically found in Asia and Europe </li></ul></ul><ul><ul><li>Result of reassortment of human and swine influenza viruses </li></ul></ul>
  4. 4. H1N1 – history <ul><li>1918 flu pandemic – “Spanish flu” </li></ul><ul><li>1930 </li></ul><ul><li>1976, 1988 – isolated human cases </li></ul><ul><li>1998, 2007 – in swine </li></ul><ul><li>2009 pandemic </li></ul><ul><ul><li>Respiratory illness outbreak in March/April 2009 </li></ul></ul><ul><ul><ul><li>Patient zero was a 6 month old girl in Mexico </li></ul></ul></ul><ul><ul><li>Farm in Alberta with a link to the outbreak in Mexico </li></ul></ul>
  5. 5. H1N1 Pandemic <ul><li>World Health Organization (WHO) definition </li></ul><ul><ul><li>emergence of a disease new to a population </li></ul></ul><ul><ul><li>agents infect humans, causing serious illness </li></ul></ul><ul><ul><li>agents spread easily and sustainably among humans </li></ul></ul><ul><ul><li>6 levels - geographical </li></ul></ul><ul><li>Must be infectious i.e. not cancer </li></ul><ul><li>H1N1 – pandemic as of June 2009 </li></ul>
  6. 6. H1N1 Spread <ul><li>When someone coughs or sneezes, tiny droplets filled with virus can travel up to two metres away. </li></ul><ul><li>If these droplets land in your eyes, nose or mouth, you may become infected with the virus. </li></ul><ul><li>Doorknobs, pens </li></ul><ul><li>Not through pork </li></ul>
  7. 7. Attacking the Body <ul><li>Starts in the nose and then moves into lower airways </li></ul><ul><ul><li>No symptoms </li></ul></ul><ul><li>Attaches to cells and divides </li></ul><ul><ul><li>Symptoms may start </li></ul></ul><ul><ul><li>2-7 days for symptoms to begin after ‘infection’ </li></ul></ul><ul><ul><li>Strength of immune system determines path taken </li></ul></ul>
  8. 8. Symptoms <ul><li>Almost always : </li></ul><ul><li>Cough and fever (≥100° F / 37.8° C) </li></ul><ul><li>Common: </li></ul><ul><li>Fatigue </li></ul><ul><li>Muscle aches </li></ul><ul><li>Sore throat </li></ul><ul><li>Headache </li></ul><ul><li>Decreased appetite </li></ul><ul><li>Runny nose </li></ul><ul><li>Sometimes: </li></ul><ul><li>Nausea </li></ul><ul><li>Vomiting </li></ul><ul><li>Diarrhea </li></ul><ul><li>Cold vs flu? </li></ul><ul><li>Seasonal flu vs H1N1? </li></ul>
  9. 9. Who? <ul><li>Median age of confirmed cases: 12 years </li></ul><ul><li>Median age of hospitalized cases: 20 years </li></ul><ul><li>Median age of lethal cases: 37 years </li></ul><ul><li>>65 years of age </li></ul><ul><li> Hospitalized Deaths </li></ul><ul><li>Seasonal flu 60% 90% </li></ul><ul><li>2009 H1N1 5% 8% </li></ul>
  10. 10. Who? <ul><li>Patients hospitalized with H1N1 influenza </li></ul><ul><li>Adults with associated risks </li></ul><ul><ul><li>asthma, chronic lung or heart disease </li></ul></ul><ul><li>Children with associated risks </li></ul><ul><ul><li>asthma, chronic lung disease, neurologic disease, or sickle cell disease </li></ul></ul><ul><li>6% were pregnant women </li></ul>
  11. 11. Who? <ul><li>Case fatality is reported to be 0.4% </li></ul><ul><li>2.4% for the 1918 influenza pandemic </li></ul><ul><li>0.1% for seasonal flu </li></ul><ul><li>The highest death rate is in persons 50-64 years. </li></ul>
  12. 12. H1N1 Vaccine <ul><li>Arepanrix from GlaxoSmithKline </li></ul><ul><li>Stimulates an immune response using a killed or weakened virus that uses the body’s own defense mechanisms to prevent infection. </li></ul><ul><li>With the H1N1 flu vaccine you will have some immunity to the current strain of the H1N1 flu virus within 10 – 21 days. </li></ul>
  13. 13. H1N1 Vaccine <ul><li>Priority groups for immunization clinics: </li></ul><ul><ul><li>pregnant women </li></ul></ul><ul><ul><li>children 6 months to 5 years </li></ul></ul><ul><ul><li>under 65 with chronic conditions </li></ul></ul><ul><ul><li>people who live with or care for infants under 6 months old </li></ul></ul><ul><ul><li>immuno-compromised </li></ul></ul><ul><ul><li>healthcare workers </li></ul></ul>
  14. 14. H1N1 Vaccine <ul><li>Egg – potential allergen </li></ul><ul><li>Thimerosol in multi-dose vials </li></ul><ul><ul><li>mercury </li></ul></ul><ul><li>Adjuvant </li></ul><ul><ul><li>Boosts an immune response </li></ul></ul><ul><ul><li>Stretches out a vaccine to provide more </li></ul></ul><ul><ul><li>Vitamin E, squalene (shark liver oil), and water </li></ul></ul>
  15. 15. H1N1 Vaccine – Pregnancy <ul><li>Adjuvanted for 20 weeks + or with underlying conditions. </li></ul><ul><ul><li>Adjuvanted now considered ok <20 weeks (Oct 30, 2009) </li></ul></ul><ul><li>Unadjuvanted vaccine is considered the preferred option. </li></ul><ul><ul><li>extensive experience regarding the safety of unadjuvanted seasonal influenza vaccines in pregnant women </li></ul></ul><ul><ul><li>there is currently no data on the safety of the adjuvanted H1N1 vaccine in this group </li></ul></ul>
  16. 16. H1N1 Vaccine <ul><li>Who Shouldn’t Get the Vaccine? </li></ul><ul><li>Not approved for children under six months of age. </li></ul><ul><li>You have had a previous anaphylactic (severe allergic reaction) to any element of the vaccine. </li></ul><ul><li>You have a hypersensitivity to eggs (e.g. hives, swelling of mouth and/or throat, breathing difficulty). </li></ul><ul><li>You currently have a high fever. </li></ul><ul><li>You have experienced Guillan-Barre Syndrome within eight weeks of receiving a seasonal flu vaccine. </li></ul>
  17. 17. Conventional Treatment <ul><li>Antivirals </li></ul><ul><li>Must be taken within the first 24 to 48 hours after getting sick </li></ul><ul><li>Available in two forms: </li></ul><ul><ul><li>a pill (called oseltamivir or Tamiflu®) </li></ul></ul><ul><ul><li>an inhaler (called zanamivir or Relenza®). </li></ul></ul>
  18. 18. Prevention <ul><li>Wash your hands. </li></ul><ul><li>Disinfect door knobs, surfaces. </li></ul><ul><li>Sneeze into your sleeve. </li></ul><ul><li>Avoid large crowds. </li></ul><ul><li>Alcohol-based hand sanitizer. </li></ul>
  19. 19. Naturopathic Immune Strategies <ul><li>Nutrition </li></ul><ul><ul><li>More fruits, veggies, garlic, onions, less sugar and alcohol </li></ul></ul><ul><ul><li>Vitamin D, probiotics </li></ul></ul><ul><li>Herbal </li></ul><ul><ul><li>Astragalus, cat’s claw, licorice </li></ul></ul><ul><li>Lifestyle </li></ul><ul><ul><li>Gargle with warm salt water, neti-pot </li></ul></ul><ul><ul><li>Stress management </li></ul></ul><ul><ul><li>Sleep </li></ul></ul>
  20. 20. Resources <ul><li>http://www.phac-aspc.gc.ca/alert-alerte/h1n1/index-eng.php </li></ul><ul><li>http://www.who.int/en/ </li></ul><ul><li>http://www.motherisk.org/women/index.jsp </li></ul><ul><li>http://www.flu.gov/index.html </li></ul><ul><li>Thank you! </li></ul><ul><li>Carol Morley, ND </li></ul><ul><li>Zawada Health, 201 City Centre Drive, Mississauga </li></ul>

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