2011
Nurse’s
Drug
Handbook
92381_FMxx_pi-xx 6/2/10 7:13 PM Page iii
The Drug Reference
That Gives You More!
Take drug information with you wherever you go!
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Jones & Bartlett Learning
2011
Nurse’s
Drug
Handbook
Tenth Edition
92381_FMxx_pi-xx 6/2/10 7:13 PM Page v
World Headquarters
Jones & Bartlett Learning books and products are available through most bookstores and online book-
sel...
Advisors, Reviewers, and Clinical Consultants ix
How to Use This Book xiv
Foreword xix
Overview of Pharmacology 1
Principl...
92381_FMxx_pi-xx 6/2/10 7:13 PM Page viii
Jack E. Fincham, RPh, PhD
Dean and Professor of Pharmacy
Practice
School of Pharmacy
University of Kansas
Lawrence, KS
Mar...
Reviewers
Peter J. Ambrose, PharmD
Associate Clinical Professor, Step III
Director
Los Angeles-Orange County Area
Clerkshi...
Jan K. Hastings, PharmD
Assistant Professor
College of Pharmacy
University of Arkansas for Medical
Science
Little Rock, AR...
xii
Reviewers (cont’d)
Vinita B. Pai, PharmD
Assistant Professor of Pharmacy
Practice
College of Pharmacy
Idaho State Univ...
Clinical Consultants
Madeline Albanese, RN, MSN
Nurse Educator
Hospital of the University of
Pennsylvania
Philadelphia, PA...
Jones & Bartlett Learning 2011 Nurse’s
Drug Handbook gives you what today’s
nurses and nursing students need: accu-
rate, ...
on the drugs that you’ll typically admin-
ister. To help you find the information
you need quickly, drug entries are organ...
xvi
for each administration route. The onset
of action is the time a drug takes to be
absorbed, reach a therapeutic blood ...
xvii
Teaching your patient about drug therapy
Your teaching about drug therapy will vary with your patient’s needs and you...
xviii
time, however, this section doesn’t repeat
basic patient-teaching points. (For a
summary of those, see Teaching your...
Safe, effective drug therapy is one of your
most important responsibilities. Not
infrequently, a patient’s life will depen...
xx
The Physicians’ Desk Reference, the FDA’s
website of new drug approvals, and the
USP DI’s Drug Information for the Heal...
Understanding the basics of pharmacolo-
gy is an essential nursing responsibility.
Pharmacology is the science that deals
...
modifiers, antineoplastic enzymes, and
hormonal antineoplastics.
Pharmacokinetics
Pharmacokinetics is the study of a drug’...
absorbed into the lower GI tract, rectal
drugs enter the circulation through the
inferior vena cava, bypassing the liver a...
solutions, such as vasopressin, are admin-
istered by this route specifically to pro-
duce systemic effects.
Vaginal: Vagi...
as the protective effects of a topical oint-
ment) or chemical reaction (such as an
antacid’s effect on the gastric mucosa...
include giving drugs, including antihista-
mines and corticosteroids, to counteract
the allergic response.
An anaphylactic...
from adult dosages.
The FDA has provided drug manufac-
turers with guidelines that define pedi-
atric age categories. Unle...
Because there are thousands of drugs and
hundreds of facts about each one, taking
responsibility for drug administration
c...
tion route is missing from the prescrip-
tion, consult the prescriber before giving
the drug. Never substitute one route f...
will affect the drug’s release. You may
need to consult a pharmacist to deter-
mine which tablets can be crushed or
capsul...
Sublingual
In S.L. administration, tablets are placed
under the tongue and allowed to dissolve.
Nitroglycerin is commonly ...
A systematic approach to nursing care,
the nursing process helps guide you as
you develop, implement, and evaluate
your ca...
and ask him if he knows the results of the
latest monitoring or laboratory tests.
ALLERGIES
Find out if the patient is all...
lished by the North American Nursing
Diagnosis Association (NANDA).
One of the most common nursing
diagnoses related to dr...
Documentation
You’re responsible for documenting all
your actions related to the patient’s drug
therapy, from the assessme...
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abatacept 17
AA
abatacept
Orencia
Class and Category
Chemical class: Soluble fusion protein,
human recombinant fusion prot...
treatment, as ordered, before starting abat-
acept. Also screen patient for hepatitis B. If
present, expect abatacept to b...
forming a clot that eventually blocks a
coronary artery. By binding to receptor
sites, abciximab prevents normal binding o...
acamprosate calcium20
GABA
Glutamate
Glutamate
Glutamate
Glutamate
ReceptorReceptor
Receptor
Receptor
ReceptorReceptor
Rec...
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