Cinderella's approach

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What advantages does Cinderella’s approach bring? Important advantages are illustrated in this presentation, including renouncing the profit principle, restarting the interrupted development of drugs considered to have insufficient potential for the generation of profits and bringing new drugs to patients for an affordable price by using a scientifically and economically sound study design

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Cinderella's approach

  1. 1. Cinderella is the first Dutch not-for-profit organization making new drugs available for an affordable price.
  2. 2. Cinderella focuses on step child drugs: Promising drugs, but of low interest to the commercial pharmaceutical industry due to their low potential to generate profits.
  3. 3. Cinderella is convinced the clinical development of stepchild drugs can be completed successfully by the application on novel study methodology.
  4. 4. To reach this goal Cinderella renounces the profit principle and adopts top clinical physician/scientists to execute her projects. Charity organizations and individuals who subscribe to Cinderella’s approach will provide the necessary financial support .
  5. 5. Initiate development of stepchild drugs by initiating clinical: Renouncing the profit principle. Selecting the most promising step child drugs.
  6. 6. Cinderella’s drug selection: Drugs shelved by the pharmaceutical industry for their lack of profit making potential. Drugs promising a high therapeutic ratio based on results obtained in preclinical research and phase 1 studies.
  7. 7. Cinderella is only interested in phase 2 studies: Phase 2 studies can be completed in a brief period of time at low costs Short study duration and low costs are achieved by entering limited numbers of patients on study (approx. 30).
  8. 8. Drugs shelved for their inability to generate a sizeable profit can still be studied in patients. Advantages of Cinderella’s approach:
  9. 9. Drugs shelved for their inability to generate a sizeable profit can still be studied in patients. All studies focused on improving the quality of life of the patient. Top medical specialists are the principal investigators. Advantages of Cinderella’s approach:
  10. 10. Drugs shelved for their inability to generate a sizeable profit can still be studied in patients. All studies focused on improving the quality of life of the patient. Top medical specialists are the principal investigators. Coordination is in the hands of the Cinderella Therapeutics Research Corporation. Advantages of Cinderella’s approach:
  11. 11. Drugs shelved for their inability to generate a sizeable profit can still be studied in patients. All studies focused on improving the quality of life of the patient. Top medical specialists are the principal investigators. Coordination is in the hands of the Cinderella Therapeutics Research Corporation. A corporate approach leads to higher efficiency. Advantages of Cinderella’s approach:
  12. 12. Advantages of Cinderella’s approach: Cinderella subscribes to the open source principle.
  13. 13. Cinderella subscribes to the open source principle. Obtained results will be published forthwith in scientific journals. Advantages of Cinderella’s approach:
  14. 14. Cinderella subscribes to the open source principle. Obtained results will be published forthwith in scientific journals. Patent applications to protect commercial interests have become obsolete. Advantages of Cinderella’s approach:
  15. 15. No marketing costs. Advantages of Cinderella’s approach:
  16. 16. No marketing costs. Therapies found to be ineffective in Cinderella studies will not increase the price charged for other, new and effective Cinderella therapies. Advantages of Cinderella’s approach:
  17. 17. No marketing costs. Therapies found to be ineffective in Cinderella studies will not increase the price charged for other, new and effective Cinderella therapies. Cinderella’s new type of drug development will be 10 to 100 times cheaper than the current drug development strategy of the Pharmaceutical Industry. Advantages of Cinderella’s approach:

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