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Nervous System Mas Maganda
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Nervous System Mas Maganda

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  • 1. Nervous system
  • 2. Action potential
    • Caused by voltage difference across the plasma membrane
    • Due to ionic composition
      • Inside: more K + than Na +
      • Outside: more Na + than K +
      • Anions: primarily inside and composed of large molecules
  • 3. Channels
    • Channels are responsible for the permeability of the membrane
      • Voltage-gated ion channels
      • Chemically-gated ion channels
  • 4.  
  • 5. Propagation of AP
    • Neuron is stimulated
    • Voltage-gated ion channels will open
    • K will move outside due to conc gradient
    • Will return due to electrical gradient
    • Na reverse reaction of K
    • Resting membrane potential of -70mV rather than -85mV
  • 6. REMEMBER!!!!!!!!!!!!!!!
    • Dissipation of membrane potential is hindered due to the presence of the sodium potassium pump
  • 7. The very important graph
  • 8. The very important terms……
    • Polarization- creation of different charges inside/outside the cell membrane
    • Depolarization- membrane is more positive (dec in electrical gradient)
    • Hyperpolarization- membrane is more negative (inc electrical gradient)
  • 9. Terms pa rin……..
    • Threshold potential- amount of potential difference needed to create an action potential
    • Action potential- electrical stimulus that creates signal/message in an axon
    • Hyperpolarization- do not produce action potential
  • 10.
    • Graded potential if it is dependent on the amount of stimulus
    • Action potential in case of neurons that need to meet the threshold potential
  • 11. AP is the nerve impulse
    • TANDAAN!!!!!!
      • Nongraded all or none response/event
  • 12. Ang pagbabalik…….
  • 13. Ano ba nangyayari?
    • Start with voltage-gated ion channel
      • K- one gate; closed-resting, opens slowly during depolarization
      • Na- two gates; activation gate- closed-resting, opens rapidly during depolarization
      • inactivation gate- open when resting, closes slowly due to depolarization
  • 14. Huh?
    • K is responsible for hyperpolarization because they remain open during repolarization
    • Na is responsible for depolarization
  • 15. synapse
    • Voltage
    • Chemical
  • 16. EPSP vs IPSP
    • Excitatory postsynaptic potential
    • Inhibitory postsynaptic potential
      • Temporal vs summation
  • 17. Magbasa……..
    • Magbasa ng mga neurotransmitter at different kinds ng organization of nervous system
  • 18. Hyperpolarization
    • Responsible for the unidirectional movement of the action potential
  • 19.