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    Mentor Index card Mentor Index card Presentation Transcript

    • UMCCTS Mentors
    • Schahram Akbarian, MD, PhD
      Associate Professor of Psychiatry
      Director-Brudnick Neuropsychiatric Research Institute
      • Internationally recognized on the molecular
      pathology of schizophrenia & other neurodevelop-
      mental disorders
      • NIH funded since 2000, studying epigenetic
      mechanisms in the pathophysiology of depression,
      psychosis & Rett syndrome
      • 1997 NIMH Outstanding Resident Award
      • 2008 NARSAD Staglin Family Schizophrenia
      Research Award
      • Mentored more than 10 instructors & assistant
      professors, post-doc fellows & graduate students
    • Jeroan Allison, MD, MS
      Professor & Vice Chair-Quantitative Health Sciences
      Associate Vice Provost for Health Disparities
      • Research focuses on quality measurement, implementation science, and statistical methods, with special emphasis on eliminating racial/ethnic disparities
      • 10-year history of sustained extramural funding, including the NIH, AHQR, RWJ Foundation
      • Co-Editor-in-Chief of Medical Care, sponsored by American Public Health Association
    • Dario Altieri, MD
      Professor of Cancer Biology
      Chair-Department of Cancer Biology
      • Internationally recognized for work on cell
      death regulation and survival in human
      diseases, including cancer & acute vascular injury
      • Led development and preclinical characterization
      of apoptosis modifiers now in clinical trials
      • NIH funded since 1989; MERIT award from
      Heart, Lung and Blood Institutes
      • Mentored more than 25 pre- and post-doc
    • Victor Ambros, PhD
      2008 Lasker Prize for Basic Medical Research
      Silverman Chair in Natural Sciences
      Professor of Molecular Medicine
      • Developmental geneticist using the nematode Caenorhabditiselegans to study genetic regulatory mechanisms that control animal development
      • Major focus on microRNAs function in gene
      regulatory networks
      • NIH funded for more than 20 years
      • 2008 Gairdner International Award; Benjamin
      Franklin Medal in Life Sciences
      • National Academy of Sciences Member
      • Mentored more than 20 students & post-docs
    • Elliot Androphy, MD
      Professor and Vice Chair of Medicine
      • Internationally recognized expert on the molecular
      biology of human papillomaviruses, studying novel
      drug-like compounds to inhibit a key viral protein
      & can be used to treat HPV induced malignancies
      • NCI funded to develop drug for cervical cancer
      • Also internationally known expert in the patho-
      genesis of spinal muscular atrophy (SMA)
      • NIH funded through NICHD & the Chemical
      Genomics Center NIMH Roadmap grant
      • Mentored more than 30 post-doc fellows, graduate
      & medical students
    • Neil Aronin, MD
      Professor of Medicine and Cell Biology
      Chief-Division of Endocrinology and Metabolism
      • Internationally recognized expert on the
      pathogenesis of Huntington’s disease
      • Directs the Neuroendocrinology Laboratory
      • Basic research focuses on gene silencing for
      autosomal dominant, neurodegenerative disease
      • Clinical research examines human growth
      hormone in patients with hypopituitarism &
      genetics of familial & sporadic pheochromocytoma
      • NIH or NSF funded since 1979
      • Mentors MD/PhD & PhD students & sponsors
      post-doc fellows for NIH & HHMI
    • Leslie Berg, PhD
      Professor of Pathology
      Chair-Immunology & Virology Program
      • Internationally recognized expert on lymphocyte signaling, investigating the functions of key tyrosine kinases required for T cell activation &
      the generation of a productive immune response to infections
      • NIH funded to study signaling proteins in mouse models of immunity
      • Chair of the Board of Scientific Counselors for
      the National Institute on Aging
      • Mentored over 30 graduate students & post-docs
    • Silvia Corvera, MD
      Professor of Molecular Medicine
      • The Corvera lab studies the cellular & molecular
      basis of energy metabolism
      • NIH funded studies elucidate factors controlling
      angiogenesis in human adipose tissue
      • Bariatric surgery studies are performed in tight
      coordination & collaboration with surgeons &
      endocrinologists & closely involve residents,
      mentored in the basic aspects of the research
      • Mentored more than 10 students & post-doc
      fellows in the past 5 years
    • Michael Czech, PhD
      Professor of Molecular Medicine
      Founding Chair-Program in Molecular Medicine
      • Recognized for major contributions to diabetes
      research and adipocyte biology
      • NIH MERIT award; 2000 Banting Medal of the
      American Diabetes Association
      • Czech laboratory focuses on the underlying
      mechanisms of insulin signaling & the molecular
      basis of insulin resistance in obesity & type 2
      • NIH funded for more than 25 years
      • Mentoreddozens of graduate students & post-
      doc fellows
    • Roger Davis, MA MPhil, PhD, FRS
      Howard Hughes Medical Institute Investigator
      H. Arthur Smith Chair & Professor of Molecular Medicine
      • Internationally recognized expert in signal
      transduction mechanisms related to the stress
      • NIH-funded
      • Research on cancer, diabetes, inflammation, &
      stroke has helped identify new molecular targets
      • Elected to The Royal Society (London) in 2002
      • Editor-in-Chief, Molecular & Cellular Biology
      • Mentored many trainees; now successful faculty
      at other Medical Schools
    • Kate Fitzgerald, PhD
      Associate Professor of Medicine
      • Internationally recognized expert on innate
      immunity and host defense with a particular focus
      in pattern recognition receptors (Toll-Like
      Receptors, RIG-Like Receptors, NOD-Like
      Receptors) and their associated signaling pathways
      • Recipient of several Young Investigator awards
      • NIH funded since 2004
      • Actively involved in the Immunology & Virology
      • Mentored post-doc fellows, graduate & medical
    • Terence Flotte, MD
      Dean, Provost, Executive Deputy Chancellor
      Professor of Pediatrics
      • Internationally recognized as a pioneer in human
      gene therapy, currently investigating its use for
      pediatric genetic diseases, mainly Cystic Fibrosis
      • First to use adeno-associated virus (AAV) to
      deliver corrective genes to targeted sites in the
      body, including the damaged airways of adults
      with CF, paving the way for new viral vectors for
      CF gene therapy, currently undergoing pre-clinical
      testing & soon to be tested in patients
      • Mentored more than 20 individuals
    • Patricia Franklin, MD MBA MPH
      Associate Professor of Orthopedics &
      Physical Rehabilitation, Director-Musculoskeletal Clinical &
      Outcomes Research, Director-Clinical/Translational Research
      Pathway for Medical Students
      • Expert in clinical and outcome data analysis
      • NIAMS-funded research on intervention to
      Enhance TKR patient adherence during rehab
      • RWJF-fundedeHealth research includes a
      multi-site trial testing the efficacy of emails on
      diet & physical activity change & development
      of web-based outcome prediction tools
      • Supervises orthopedic clinical research of
      residents (MD) & pre- & post-doc trainees
    • Robert Goldberg, PhD
      Professor of Medicine and Epidemiology
      Director-Master of Science in Clinical Investigation
      • Internationally recognized for research in cardiovascular epidemiology & preventive cardiology
      • NIH funded for 25 years; current MERIT awardee
      • Recent NIH funding for two large scale
      epidemiologic studies, one to understand care
      seeking in patients with acute heart failure, the
      other studying venous thromboembolic disease
      • Senior Epidemiologist for the GRACE (Global
      Registry of Acute Coronary Events)
      • Mentored more than 50 post-doc fellows,
      medical & graduate students
    • Douglas Golenbock, MD
      Professor of Medicine, Molecular Genetics
      & Microbiology
      Chief-Division of Infectious Diseases
      • Internationally recognized expert on the innate
      immune system, particularly in the recognition &
      response to microbial products
      • Recent work includes collaboration with Brazilian
      investigators on patient studies in the patho-
      Genesis of P. falciparum malaria
      • NIH funded since 1987; currently an NIH MERIT
      awardee from NIGMS
      • Mentored more than 40 post-doc fellows,
      graduate & medical students, & ID fellows
    • Ellen Gravallese, MD
      Professor of Medicine & Cell Biology
      Chief-Division of Rheumatology
      • Internationally recognized expert on pathogenesis
      of rheumatoid arthritis (RA), with recent emphasis
      on the destruction of joint bone & cartilage
      • Lab uses animal models of RA & patient tissue
      samples to understand pathogenic mechanisms of disease & identify novel treatment pathways
      • Harvard Medical School Scholars in Medicine Award
      • NIH and Arthritis Foundation funded
      • Mentored 14 post-doc fellows, graduate & medical students, & rheumatology fellows
    • Michael Green, MD, PhD
      Professor of Molecular Medicine
      Howard Hughes Medical Institute Investigator
      Director-Program in Gene Function & Expression
      • Internationally recognized expert in eukaryotic
      gene regulation & its role in human cancers
      • Uses molecular biology, molecular genetics,
      biochemical & RNA interference technology to
      perform genome-wide screens to identify new
      genes & pathways & address questions in cancer
      molecular biology
      • NIH funded since 1984
      • Mentored more than 90 post-doc fellows,
      graduate & MD/PhD students
    • Jerry Gurwitz, MD
      Dr. John Meyers Professor in Primary Care Medicine
      Executive Director- Meyers Primary Care Institute
      Chief-Division of Geriatric Medicine
      • Recognized for expertise in optimal drug therapy
      in the elderly & improving medication safety
      • Agency for Healthcare Research & Quality funded;
      NHLB-funded HMO Cardiovascular Research Network
      • William B. Abrams Award in Geriatric Clinical
      Pharmacology; George F. Archambault Award;
      • John M. Eisenberg Patient Safety and Quality
      • Mentored over 25 trainees
    • Thomas K. Houston, MD, MP
      Director-Division of Health Informatics & Implementation Science
      Professor of Quantitative Health Sciences & Medicine
      • Leader in health informatics & technologically-
      based, patient-centered interventions to improve clinical care
      • Funded through NIH & VA
      • Co-chair, Behavioral Informatics Group, Society of Behavioral Medicine
      • Chair, Consumer Health Informatics working group, American Medical Informatics Assoc
      • Editorial board, Journal of Medical Internet Research Thomas.Houston@umassmed.edu
    • ShaleshKaushal, MD, PhD
      Associate Professor of Ophthalmology
      Chair-Department of Ophthalmology
      • Expert in vitreoretinal disorders & first in the world
      to use complement inhibitor molecules to treat
      patients for wet age-related macular degeneration
      • Current research uses gene therapy to treat a
      congenital blindness known as Leber Congenital Amaurosis
      • Basic research targets the biochemical basis of
      retinal & macular degeneration, including small
      molecule drug discovery & the molecular & cellular
      fate of misfolded proteins associated with retinal degeneration
    • Catarina Kiefe, PhD, MD
      Professor and Founding Chair-Quantitative Health Sciences
      • Continuous research funded since 1993 by the NHLBI, NCI, AHRQ, VA, and CDC
      • Nationally and internationally recognized for work in quality health care measurement and patient outcomes improvement
      • Associate Editor of the Annals of Epidemiology (1995-2000)
      • Co-Editor-in-Chief of Medical Care
      • Afounding Senior Scholar in the VA National Quality Scholars Fellowship
      • Mentored over 60 post-doc trainees & junior faculty Catarina.Kiefe@umassmed.edu
    • John Keaney, MD
      Professor of Medicine & Physiology
      Chief-Division of Cardiovascular Medicine
      • Internationally recognized expert on vascular & endothelial cell biology
      • Research involves biochemical, cellular, animal & human manifestations of vascular disease
      • NIH funded since 1995, including Multidisciplinary Training in Cardiovascular Research grant
      • Mentored over 25 post-doc fellows, graduate & medical students, & cardiology fellows
    • Katherine Luzuriaga, MD
      Professor of Pediatrics & Molecular Medicine
      Director-Clinical Research Scholars (K12) Program
      Associate Provost-Global Health
      • Internationally recognized for Informing
      understanding of viral & host factors influencing
      the establishment of persistent viral infections
      (HIV, CMV, and EBV) in infants & children
      • First to characterize the ability of young infants to generate virus-specific CD8 T cell responses & to demonstrate the efficacy of early antiretroviral treatment in HIV-infected infants
      • NIH funded; NIH Mid-Career Award to mentor
      graduate students, post-doc fellows, & jr faculty
    • Craig Mello, PhD
      2006 Nobel Prize in Medicine or Physiology
      Howard Hughes Medical Institute Investigator
      Blais University Chair in Molecular Medicine
      Director-RNAi Therapeutics Institute
      • Internationally recognized as co-discoverer
      of RNAi, a process & state-of-the-art method by
      which scientists “knock-out” or silence the
      expression of specific genes to identify the
      gene’s function
      • Mentored more than 40 post-doc fellows &
      graduate students
    • John L. Sullivan, MD
      Vice Provost for Research
      Director-UMass Center for Clinical & Translational Science
      Professor of Pediatrics & Molecular Medicine
      • Internationally recognized for pioneering use of
      nevirapine to reduce HIV maternal-to-fetal trans-
      mission in sub-Saharan Africa
      • Ongoing research focuses on immunopathogenic
      consequences of HIV infection & pathogenesis of
      herpes virus infection
      • NIH funded more than 25 years
      • Mentored 6 graduate students & 12 post-doc
    • Gyongyi Szabo, MD, PhD
      Professor of Medicine
      Director-Medical Scientist Program
      Associate Dean-Clinical & Translational Science
      • Internationally recognized authority on the role
      of innate immunity in liver disease
      • NIH funded since 1990
      • Research includes animal models & patients with hepatitis C infection, alcoholic & non-alcoholic
      liver disease
      • PI on the HALT-C multi-center NIDDK-supported
      clinical trial
      • Mentored 18 post-doc fellows
    • Carole Upshur, EdD
      Professor of Family Medicine & Community Health
      Associate Dean-Clinical & Population Health Research
      • Nationally known researcher on the
      integration of primary care & mental health
      services, organization & management of
      behavioral health care for children, & treating
      chronic pain in primary care
      • Funded through AHRQ, NIMH, Robert Wood
      Johnson & Annie E. Casey Foundations, &
      Health Foundation of Central Massachusetts
      • Mentored over 30 doctoral students
    • Zhiping Weng, PhD
      Professor of Biochemistry & Molecular Pharmacology
      Director-Program in Bioinformatics & Integrative Biology
      • Known for contributions in two areas—
      transcriptional regulation & protein-protein
      • PI on National Human Genome Research
      Institute grant to computationally predict &
      experimentally test transcriptional factor
      binding sites in the human genome (part of
      the International Consortium called
      Encyclopedia of DNA Elements (ENCODE)
      • Mentored more than 30 trainees
    • Phillip Zamore, PhD
      Howard Hughes Medical Institute Investigator
      Gretchen Stone Cook Professor of Biomedical Sciences
      Professor of Biochemistry & Molecular Pharmacology
      • International leader in the study of RNAi
      & other RNA silencing pathways
      • NIH funded; High Q Foundation grant to develop
      therapies for Huntington’s disease
      • Pew Scholar in Biomedical Sciences; W.M. Keck
      Foundation Young Scholar in Medical Research;
      Schering Plough Award
      • Mentored more than 25 trainees, including
      medical and graduate students, PhD/MDs, &
      post-doc fellows
    • Douglas Ziedonis, MD, MPH
      Professor of Psychiatry
      • International expert on co-occurring
      mental illness & addiction, in particular tobacco dependence & including developing innovative programs, research training, & policy
      • NIH funded through NIMH, NIDA, & CSAT
      • Senior Fellow, SAMHSA’s Co-Occurring
      Disorders Center for Excellence
      • Norman H. Edelman Clinical Sciences Mentoring Award
      • Developed “Training the Mentor” programs