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Most common initial treatments (% those treated); 2002-5
Other improvements Published experience Increased use of electronic data at source Merging datasets
Validation GPRD validations 357 validations 183 diagnoses median cases confirmed 89% range 24–100% Herrett, E et al, British Journal of Clinical Pharmacology 2010
Validation Deaths in 1 year (THIN) 99.6% of 1,399 deaths had died In medical & admin. files as well as designated field 0.3% of deaths <1 year dated 366-485 days Hall GC, Pharmacoepidemiol Drug Saf 2009
Validation 63% had an electronic COD 47% from coded entries 17% from free text
Validation 7 suicides were identified 1 was coded as suicide 2 had a cause of death indicative of suicide 4 had no cause of death or indication of suicide