Quality Products for Quality Life Products for a variety of Seasons & ReasonsOne the fastest growing pharmaceutical companies CORE GROUP is known growing,for developing and marketing one of the lowest cost high quality safe cost, quality, safe,effective and proven medicines for a wide variety of seasons and reasons The reasons.aim is to help people live longer, live better.Core Group’s varied product basket includes prescription Antibiotics & Life Saving medicines,Analgesic & Pain Killers, Gynecological, Pediatric, Gastrointestinal, Orthopedics, Injectibles andexpectorants. The gynecological range may further be sub-divided into Calcium Supplements,Iron Supplements, Multi-vitamin, Multi-mineral and products for anti-nauseant / antiemeticmanagement of nausea and vomiting during Pregnancy (NVP). Likewise the gastrointestinalrange includes Anti-emetic, Anti-Anorexia, Antacids and Anti-Secretary medicines.To add further punch to its gastrointestinal range the company is now launching a new productcalled Hitolive (L-ornithine L-aspartate) –a prescription drug for severe liver impairment. L-Ornithine-L-Aspartate is useful in the treatment of high ammonia levels or when a patient’sliver function is extremely poor. L-O-L-A is very effective for end-stage cirrhotic patients.All these products are manufactured as per US Food and Drug Administration (USFDA) andWorld Health Organizations Good Manufacturing Practice (WHO GMP) Regulations.Sometimes also referred to as cGMPs or Current Good Manufacturing Practices these are a setof regulations, codes, and guidelines for the manufacture of drugs, medical devices, diagnosticaids and Active Pharmaceutical Ingredients (APIs) to ensure ensures a drug with zero defects.GMP is a concept that goes beyond manufacturing. It involves commitment to total qualityacross the organization. It is something imbibed in the very culture of the organization. One ofthe essential requirements of GMP is to maintain high degree of sanitation and hygienicconditions in the manufacturing facilities and by the personnel operating the machines. TheWorld Health Organization (WHO) version of GMPs is used by pharmaceutical regulators andthe pharmaceutical industry in over 100 countries worldwide, primarily in the developing world.Anyone using Core’s products is assured of finest quality, safe and reliable productsmanufactured with utmost care. Core’s Group products are manufactured at state-of-the-artmanufacturing facilities conforming to stringent international WHO and GMP norms. The entireproduction process is carried out at per well-defined Standard Operating Procedures (SOP) andquality control checks from raw materials to finished goods. Most of these facilities have ultra-modern state-of-the-art machinery and trained manpower at each stage to produce world
class, safe and reliable pharmaceutical products. Another aspect of Core Group’s strength isthat many of the production units manufacturing its products are US-FDA approved. This is nomean achievement considering the fact that India has the distinction of having the largestnumber of US-FDA approved manufacturing units, outside of the United States for productionof Active Pharmaceutical Ingredient (API).ANTIBIOTICS & LIFE SAVING PRODUCTSCore Group’s key strength lies in its vast range of broad spectrum antibiotics and life savingproducts. Derived from the synthesis of two Greek words Anti – meaning “against" and Bios –meaning "life" – Antibiotics – are essentially chemicals that destroy or prevent the growth andreproduction of many types of germs and bacteria. Antibiotics are powerful medicines that fightbacterial infections. They can be injected, given orally, or applied to the skin in ointment form.Antibiotic are commonly classified as Penicillins, Cephalosporins, Fluoroquinolones,Tetracyclines, Macrolides, Aminoglycosides, Sulfonamides, Carbapenems, Polypeptides andNitro-imidazole. Of these Core Group has products under Penicillins (Remoxid-625, Remoxid-DCL & Remoxid-kid) Cephalosporins (Alcepid, Alcepid kid, Cefiante and Cefiante – Kid)Fluroquinolones (Levid & Oflina Oz)GYNEACOLOGICAL:Another weapon in Core Group’s arsenal is its wide range of Gynecological products rangingfrom Calcium supplement with Calcium and vitamin D3 combination (Calider), Iron supplements(Sanger & Sanger Plus) Antihistaminic–Antiemetic drug for nausea and vomiting duringpregnancy (Folicante-D), comprehensive health supplement with a wide range of vitamins,minerals and other nutrients that contribute to overall health and wellness (Provytal) andNutritional Dietary Supplement with Multi Vitamins & Multi Minerals (Alvitina).Recent study has demonstrated that giving calcium supplements to women during pregnancyhelp prevent tooth decay in the mother as well as child. The study revealed that children whosemothers who took calcium supplement had a 27 percent less missing teeth and decay in bothpermanent and primary teeth. The study went on to suggest that taking calcium supplement bywomen during pregnancy provides prolonged protection throughout childhood. When it comesto that the situation is really grim as most Indian women are calcium deficient. According toArthritis Foundation of India, majority of Indian women are calcium as well as Vitamin Ddeficient. On an average, a healthy woman needs 1,000 mg of calcium per day. But Indianwomen have a dietary intake of around 400-500 mg of calcium a day (provided they take twoglasses of milk, paneer and curd). This in other words means that most Indian women have adeficiency of almost 500 mg. In addition to this they have Vitamin D levels of around 4 to 12nanograms, as against a recommended level of around 30 nanograms.
For bone health, Vitamin D and calcium go hand in hand. Though itself not a Vitamin but aHormone-- Vitamin D keeps bones strong, protects against diabetes, tuberculosis, cancer, colds,and flu. Studies have indicated Vitamin D deficiency doubles the risk of hypertension duringpregnancy. Vitamin D is essential for the Calcium absorption. Vitamin D helps absorb Calciumfrom the digestive tract.Similarly Iron (Fe) — is essential to most life forms. A component of red blood cells andmuscles, it assists in transportation of oxygen throughout the body. Almost two-thirds of iron inthe body is found in hemoglobin, the protein in red blood cells that carries oxygen to tissues.Women lose twice the amount of iron than men and are more likely to be deficient, particularlyduring the child bearing years. Iron requirements of pregnant women are approximately doublethat of normal women because of increased need of the fetus, and blood losses during delivery.A pregnant woman requires 30mg of iron per day particularly during second and thirdtrimester. If iron intake does not meet increased requirement, this could lead to iron deficiencyor anemia which is responsible for morbidity, premature deliveries and low birth weight babies.This apart, Nausea and vomiting (NVP) -- often referred to as "morning sickness" is one of themost common medical conditions during pregnancy, affecting almost 80% of all pregnantwomen. Since each woman and each pregnancy is different, the severity and the managementof NVP will vary from woman to woman.PEADIATRIC:Core Group has a well defined pediatric range with MultiVitamins & MultiMinerals drops(Alvitina-Kid), oral third generation cephalosporin antibiotics (Cefiante-Kid & Alcepid-Kid),Broad spectrum Penicillin Derivative antibiotic (Remoxid-kid), quinolone antibiotics (Oflina OZ).ANALGESICS & PAIN KILLERSLikewise Core Group’s range of Analgesic Painkillers include non-steroidal anti-inflammatorydrug (NSAID) with analgesic and antipyretic properties (Nimante P), Analgesic and Anti-inflammatory, Antirheumatic for management of moderate to severe or chronic pain (Indoler Pand Indoler APS).GASTROINTESTINALIn keeping with its name Core Gestra which itself is derived from “gastric” or relating to thestomach or digestive tract, the Company’s gastrointestinal collection includes proton pumpinhibitors for treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD) (Lapanto40 and Lapanto DSR), digestive aid for easy digestion of starch, carbohydrates, fats & proteinsand mitigation of loss of appetite (Easy Zyme) and antacid (Mycid Gel).
ORTHOPEDIC:Core Group’s Orthopedic product range include Calcium supplement with vitamin D3 (Calider),centrally acting opioid analgesic, used in treating moderate to severe pain (Indoler P andIndoler APS), non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyreticproperties (Nimante-P)INJECTIBLES:A popular belief, particularly in rural India is that injections are more effective and act fasterthan oral medication. Tablet, Syrup, Inhaler, Ointment, Capsule or Injection— ever since timesimmemorial, an ongoing debate in the medical fraternity has been to find out the mostappropriate means of administrating a particular medication to a particular patient. It wouldnot be wrong to say that it’s one thing to take the right medicine but unless it is absorbed in thebody in sufficient quantity… it does not work.All over the world injections have become one of the most common medical procedures informal and informal health care settings today. According to an estimate over 40 billioninjections are administered worldwide annually.Injections are one of the fastest ways of getting a drug to the brain by injecting it directly intothe bloodstream. Intravenous injection ("mainlining") triggers effects almost before a user canpull out the needle. Given at the right time and right manner an injection can make a differencebetween life and death. The effect of the injection can also be formulated to last days ormonths.Typically the Core Group’s injectible range includes amino glycoside used to treat differenttypes of bacterial Infections (Amikante), third-generation cephalosporin antibiotics (Triader &Triader S) Proton Pump Inhibitor (PPI) that suppresses the final step in gastric acid production(Lapanto 40 Inj) and extended-spectrum penicillin antibiotic (Pipante TZ).EXPECTORANTWhen diabetes and hypertension are fast becoming lifestyle altering diseases, cough and coldmedications still remain the largest selling segment in the Indian pharma market. Withphenomenal total sales worth Rs 270 crore, Cough and cold formulations were clearly amongthe 10 top selling brands in the domestic market. Core Group’s presence in this marketed ismarket by its champion brand Moredex-AT (Terbutaline Sulphate + Bromhexine Hcl +Guaiphensin + Menthol)—an expectorant. By definition expectorants are medication that helpsbring up mucus and other material from the lungs, bronchi, and trachea, promote drainage ofmucus from the lungs by thinning the mucus and also lubricate the irritated respiratory tract.Moredex-AT eases respiratory function, breaks down mucus and facilitates expectoration.
Terbutaline is a bronchodilator to make breathing easier. Bromxhexine functions as amucolytic and mucokinetic, and facilitates ciliary clearance of the sputum while Guaiphenisin--an expectorant, acts by enhancing the output of respiratory tract fluid. By increasing thevolume of secretions in the respiratory tract, it facilitates sputum removal by ciliary action andcoughing. Moredex-AT is prescribed for relief from Cough & cold, wet cough, Allergic Cough,Smoker Cough and Pain relief.Core Group aim always and every time, is to create brands people love and contribute to abetter and healthier world. Core Group’s unending quest is to provide specialty products andinnovative solutions - that can satisfy unmet medical needs and contribute to the health andwell being of faceless and hopeless people worldwide.