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Performance enhancers bad effects of doping avik basu

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2nd and 3rd September 2011,a General Lecture Theatre, Dr Chirantan Mandal, Dr Avik Basu, Dr Dipayan Sen Dr Ushnish Adhikari,Dr Srimanti Bhattacharya, Dr Shubham Presided by Dr Arnab Sengupta …

2nd and 3rd September 2011,a General Lecture Theatre, Dr Chirantan Mandal, Dr Avik Basu, Dr Dipayan Sen Dr Ushnish Adhikari,Dr Srimanti Bhattacharya, Dr Shubham Presided by Dr Arnab Sengupta (Physiology Dept Medical College Kolkata)

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Transcript

  • 1. EXERCISE AND SPORTS PHYSIOLOGY
    PERFORMANCE ENHANCERS IN SPORTS
    Presented by:
    AVIK BASU
  • 2. WHAT IS ‘PERFORMANCE ENHANCEMENT’ IN SPORTS?
    3…
    2…
    1…
  • 3. Introduction
    In 1997, Sports Illustrated asked 198 aspiring US Olympians,
    “Would you take a banned performance enhancing substance if you were guaranteed to win and not get caught?”
    98% said “YES”
  • 4. Then, when asked,
    “Would you take the same undetectable substance if it would contribute to winning every competition for 5 years, then result in death?”
    Over 50% still said “YES!!!”
  • 5. When your best just isn’t good enough…
  • 6. DRUGS USED AS PERFORMANCE ENHANCERS
    Anabolic Agents
    Peptide Hormones and Analogues
    Creatine
    Stimulants
    Diuretics
    Cannabinoids
  • 7. ANABOLIC AGENTS AS PERFORMANCE ENHANCERS
    Anabolic Steroids
    TESTOSTERONE PRECURSORS
    • Enhance muscle mass gained from strength training
    • 8. Speed recovery after exercise
  • NAMES OF SOME ANABOLIC AGENTS
    Androstendiol
    Danazole
    Nandrolone
    Androstenedione
    DHT
    Clenbuterol
  • 9. ADVERSE EFFECTS OF ANABOLIC STEROIDS
    • Gynaecomastia, Testicular atrophy,
    Increased libido
    • Irregular menstruation, masculinization,
    acne
    • Hepatic peliosis, Hepatoma, HCC
    • 10. Adverse lipid profile
    • 11. Premature epiphyseal closure
    • 12. Mood alterations
  • PEPTIDE HORMONES AND ANALOGUES
    • Human Growth Hormone
    • 13. Insulin-like Growth factor
    • 14. Erythropoietin
    Protein anabolic action
    Newly discovered
    Increases PCV
  • 15. CREATINE
    • Regeneration of muscle ATP store
    • 16. Cr + Ph = Cr-Ph; Cr-Ph + ADP +
    H+ = Cr + ATP
    • Adverse Effects:- (1) Muscle cramps
    (2) Interstitial
    nephritis
  • 17. STIMULANTS
    Increased alertness
    Increased catecholamine
    Increased lipolysis
    CNS stimulation
    Improved respiratory function
    Allays fatigue
  • 18. DIURETICS
    • Any diuretic may be used
    • 19. Mechanism of Action:-
    (1) Body weight reduction
    (2) Elimination of other doping agents
    through urine
    • Adverse Effects:- (1) Dehydration
    (2) Cardiac arrhythmias
  • 20. CANNABINOIDS
    • Raise the pain threshold
    • 21. Adverse Effects:- (1) Lowered psychomotor
    performance
    (2) Altered perception
  • 22. METHODS OF DOPING
    • Blood Doping
    • 23. Gene Doping
    • 24. CARBOHYDRATE LOADING
  • CONCLUSION…
    Before you attempt to beat the odds…
    be sure you could survive the odds beating you
  • 25. THANK YOU!

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