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Academic Centers Research Node of PECARN

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  • 1. Academic Centers Research Node of PECARN ( “ACORN” ) Supported by Project #U03 MC00001-01 from the Maternal and Child Health Bureau, Health Resources and Services Administration, Department of Health and Human Services
  • 2. Who We Are
    • University of California, Davis Medical Center,
    • University of California, Davis School of Medicine
    • Children’s Hospital of Wisconsin,
    • Medical College of Wisconsin
    • Children’s Hospital of Philadelphia,
    • University of Pennsylvania School of Medicine
    • St. Louis Children’s Hospital,
    • Washington University School of Medicine
    • Primary Children’s Medical Center,
    • University of Utah School of Medicine
    • Children’s Hospital Medical Center,
    • University of Cincinnati School of Medicine
  • 3. University of California, Davis Medical Center University of California, Davis
    • Nathan Kuppermann, MD, MPH
    • Chair, Department of Emergency Medicine,
    • Professor of Emergency Medicine/Pediatrics
    • Emily Kim, MPH
    • ACORN Node Administrator
    • James Holmes Jr., MD, MPH
    • Trauma Consultant
    • Associate Professor of Emergency Medicine/Pediatrics
  • 4. Children’s Hospital of Wisconsin, Medical College of Wisconsin
    • Marc Gorelick, MD, MSCE
    • Medical Director, Emergency Department,
    • Professor of Pediatrics and Emergency Medicine
  • 5. Children’s Hospital of Philadelphia, University of Pennsylvania
    • Elizabeth Alpern, MD, MSCE
    • Assistant Professor of Pediatrics
    • Kathy Shaw, MD, MSCE
    • Division Chief, Pediatric Emergency Medicine,
    • Professor of Pediatrics
    • Evaline Alessandrini, MD, MSCE
    • Associate Professor of Pediatrics
  • 6. St. Louis Children’s Hospital, Washington University in St. Louis School of Medicine
    • David Jaffe, MD
    • Medical Director of Emergency Services,
    • Professor of Pediatrics
    • Walton Schalick, MD, PhD
    • Ethics Consultant
    • Assistant Professor of Bioethics, Medical History, Pediatric
    • Orthopedics & Rehabilitation
    • University of Wisconsin-Madison
  • 7. Primary Children’s Medical Center, University of Utah
    • Douglas Nelson, MD
    • Professor of Pediatrics
    • Associate Chief, Emergency Pediatric Medicine
  • 8. Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine
    • Richard Ruddy, MD
    • Director, Division of Emergency Medicine,
    • Professor of Clinical Pediatrics
  • 9. Where We Are Located
  • 10. ACORN Organizational Structure
  • 11. Key Features of the ACORN Node
    • Comprised of Three HEDA Cores
    • Administrative
    • Ethics/ Human Subjects
    • Epidemiological/Biostatistics
  • 12. Key Features of the ACORN Node
    • HEDA Cores
    • Administrative
          • Overall nodal organizational responsibility
          • Oversee generation of nodal research priority list
          • Oversee the conduct of nodal research
          • Oversee intranodal, internodal communications
          • Build partnerships with the MCHB/EMSC
  • 13. Key Features of the ACORN Node
    • HEDA Cores
    • Ethics / Human Subjects
          • Insure the protection of human subjects
          • Review ethical content of all nodal research by committee
          • Advise nodal investigators regarding all ethical issues pertaining to nodal research prior to submission to PECARN
          • Review IRB issues at nodal HEDAs and help coordinate activities which require cooperation between IRBs
  • 14. Key Features of the ACORN Node
    • HEDA Cores
    • Epidemiology / Biostatistics
          • Review nodal research proposals and provide specific feedback to investigators on issues of study design, sources of bias and confounding, sample size and power, logistics and feasibility
          • Assist in the development of surveys and other data collection instruments
          • Assist with statistical analysis of completed nodal research, including multivariable statistical models and techniques for validation
          • Assist with preparation of research presentations and manuscripts
  • 15. ACORN Proposal Generation & Review Process
  • 16. ACORN Research
    • Approved Projects:
    • Randomized Trial of Oral Dexamethasone in Acute Bronchiolitis
    • PECARN Core Data Project (with CARN)
    • Head Injury Project
    • Cervical Spine Injury Project
    • Intra-abdominal Injury Project
    • Patient Safety Project (with CARN)
    • Quality Measures Project
  • 17. Concluding Statement
    • The ACORN Node of PECARN is committed to applying our strengths and expertise to the study of the prevention and treatment of acutely ill and injured children.
    • We will forge strong collaborations with all other Nodes of PECARN and the MCHB/EMSC.
    • We are confident that the strong commitment of all the Nodes of PECARN will insure the success of this novel and exciting network.