LogPad® System with SimpleSend™ Transmissions
The Voice of the Patient — Delivered
Trustworthy Patient Data
Not too long ago, it would have seemed impossible for sponsors, sites and regulatory authorities to trust
PRO data captured outside the clinic.
• How could researchers know when a patient filled out a diary?
• How could data managers reconcile illogical responses? (For example, a patient who reports
no pain, but then rates evening pain intensity as 7 out of 10.)
• How could sites know when a patient was non-compliant, perhaps for weeks at a time, or
entering worsening symptoms?
PHT’s LogPad System has forever changed the way ePRO data are captured and managed in clinical
research. Protocol-specific eDiary applications, designed with support from PHT’s PROVision™ scientific
team, use intuitive features and quality controls to transform complicated diaries into simple ones.
• Restricted time response windows Timely and verified data entry with no unplanned recall
• Accurate timestamps bias or prospective responses.
• Reminder alarms High compliance and fewer subject drop-outs to reduce
• Regular communication with sites missing data.
• Missed Diary Minder
• Branching logic Logical, legible and complete data and significantly
• Edit checks eased respondent burden.
• Structured response options
• SafetyPRO™ alerts Proactive safety and compliance management enabled
• Missed Diary Minder by automatic email and phone alerts based on custom
criteria and thresholds The LogPad’s flexible architecture is deployed
on a range of convenient touchscreen devices
• TrueCompute™ calculations Real-time symptom and eligibility scores are performed from proven hardware manufacturers including
on field devices without having to connect to the server. Hewlett-Packard and Palm.
• 100% application integrity LogPads prevented from reverting to PDAs after soft/hard
resets or battery loss; timestamps are always accurate. PHT’s experienced PROVision science team
and expert project managers help sponsors
• Private access codes Confidentiality elicits honest subject answers in trials for determine the ideal device for their specific
sensitive indications. study and patient population requirements.
eSense™ Measurement Device Integration
Research shows that subjects report false measurement data by transcribing it incorrectly or by outright
inventing it. Consider the asthma sufferer who forgets his Peak Expiratory Flow (PEF) meter at work and
estimates an evening FEV1 score, or the diabetic patient who misreports her high blood sugar level.
eSense solves these problems by integrating objective physiological measurements directly with subjec-
tive self-assessments on the LogPad using Bluetooth, infrared and exclusive low-power RF. By ensuring
measurement devices are used appropriately and on time, according to the protocol, eSense enables
scientific researchers to ask new questions and provides sponsors with a more complete patient picture.
In one client study, 174 subjects were given the choice of either using eSense or transcribing data
manually into the LogPad after each blow into a PEF meter. 86% of 12,195 expected blows were
recorded by eSense, while only 13% were transcribed manually and less than 1% were missing.
Imagine the improvements in data reliability as compared to paper or other separate eSource methods!