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Biotechnology In Every School
 

Biotechnology In Every School

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Tina Doss ...

Tina Doss
Science Instructor/Department Head
Carlmont High School
Belmont, CA

Dan Raffa
Science Instructor
Carlmont High School
Belmont, CA

This workshop is for schools seeking to incorporate an innovative science program that will increase students’ skills in science. Participants will learn how two teachers have implemented a 3-year hands-on biotech program in their high school and learn valuable tips on how to start one in your school.

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Biotechnology In Every School Biotechnology In Every School Presentation Transcript

  • Carlmont High School Biotechnology 3-year Program Tina Doss [email_address] Dan Raffa [email_address]
  • So you want to start an Innovative Science class.
    • Goals and Objectives?
    • Target Students?
    • Teacher/Classroom?
    • Cost of Program?
    • Future Pathways?
    • Curriculum?
    • Financial Support?
    • Administrative Support?
  • Goals and Objectives
    • To better prepare students for higher education?
    • To better prepare students for industry?
    • To increase scientific literacy in students?
    • All of the above.
  • Target Students?
    • Honor students?
    • Middle 50% students?
    • Low-level or high-risk students?
    • Will you have prerequisites?
  • Teacher / Classroom
    • Who will teach the class?
      • Enthusiastic Teacher
      • Willing to learn
    • Where will it be taught?
      • Designated Space
      • Storage
      • Computers?
      • Will you have to share a room?
    • Timeline for Implementation
  • Cost of Program
    • $10,000 - $500,000
    • Length of your program
    • Series of labs
    • Computers?
  • What is Biotechnology? Manipulation of living things or their components to benefit humankind. Insulin
  • Carlmont HS Biotechnology Program
    • Why did this happen?
      • Bay Area has been a leader in the industry for over 25 years.
      • Local media such as the San Jose Mercury (December 4, 2002) point to the industry’s desperate need for a well educated workforce and mention in particular the need to draw more minority students into the sciences.
  • Carlmont HS Biotechnology Program
    • How did this happen?
      • Measure G funds
      • SSP
      • Ellyn Daugherty, Biotechnology Teacher
      • Industry Donations
  • Chemistry for Biotechnology Students: Standard Chemistry with specific Biotech applications. Caffeine Spec Analysis, Quantitative Analysis, Organic & Protein Chemistry Biotechnology 3 -4 Advanced SLOP, Plant, “How to Videos” Pharmaceutical and Agricultural Biotechnology, Diagnostic Biotechnology, Product Productivity Project Biotechnology 1-2 SLOP, Scientific Notebook, Lab Safety, DNA/ Protein Purification, Protease Project
  • Where can students go after:
    • ROP Regional Occupational Program (spring/summer program)
    • Community College (AA Bio-manufacturing)
    • UC/CSU/Private Universities
  • Skyline College - BIOMAPS Location
  • Bay Area Bioscience Cluster
    • Birthplace of Biotechnology—Cetus founded in 1971 / Genentech founded in 1976
    • 9 counties, 101 cities, 7,000 square miles of land
    • 900 Life Science Companies
    • 90,000 Employed in Bioscience Directly
    • $6 Billion Payroll
    • Average wage $68,000
    • 393 marketed products / 400 products in Phase II and Phase III
  • INTRODUCTION TO BIO SCIENCE (Employability, Life Skills, Ergonomics) CONTEXTUALIZED BIO SCIENCE LITERACY/ VESL TRAINING (100-150 hours) ASSISTANT MEDIA PREP 30K – 40K + Benefits PREPARATION (11-12 th grade literacy Training) ENTRY LEVEL TRAINING (300 hrs of community college credited course) UPGRADE E MPLOYMENT ADVANCE EMPLOYMENT Originally developed by Workforce Strategy Center GRUBER & PEREIRA ASSOCIATES, LLC. Workforce and Economic Development Consulting THE SAN MATEO REGIONAL BIOTECH CAREER LADDER SYSTEM GRUBER&PEREIRA ASSOCIATES SAN MATEO LABOR COUNCIL PENINSULA WORKS SKYLINE COLLEGE OHLONE COLLEGE STATE OF CALIFORNIA – EDD BIO INDUSTRY PARTNERS PHARMACEUTICAL MATERIALS SPECIALIST 32K – 45K + Benefits BIO PROCESS MANUFACTURING TECHNICIAN 35k – 45k + Benefits 1-3 MONTHS PAID WORK EXPERIENCE ($14.00+ per hour) BIO PROCESS/ASSISTANT MEDIA PREP/ PHARMACEUTICAL MATERIALS SPECIALIST TRAINING (Biological Sciences, Physical Sciences, Engineering) (300 hours) QUALITY CONTROL (QC) ANALYST TECHNICIAN 40k – 50k + Benefits ENTRY LEVEL EMPLOYMENT LABWARE TECH. 30K – 40K + Benefits ASST. FINAL PRODUCT INSPECTOR 30K – 40K + Benefits MFG. DOCUMENTATION REVIEWER 30K – 40K + Benefits LABELING AND PACKAGING OPERATOR 30K – 40K + Benefits 4 MONTHS UPGRADE TRAINING UPGRADE TRAINING (300 hrs of Chemistry, Biology, GMP, FDA) PAID WORK EXPERIENCE
  • SB 70 (Scott) -- Economic Development and Career Technical Education Reform Initiative
    • Senate Bill 70 provides $20 million to the California Community Colleges. The funds, which became available January 1, 2006, are being used for several types of projects:
    • "Quick Start" Partnerships, which will enhance linkages and pathways between secondary schools and selected economic and workforce development initiatives in community colleges
    • Projects that will grow program capacity and infrastructure
    • Projects that will strengthen Career and Technical Education sectors at secondary school.
  • BIOMAPS Quickstart Project
    • Meet industry-driven workforce needs;
    • Expand certificate programs
    • Develop articulated courses
    • Expand work experience opportunities,
    • Initiate mentor programs (BIOMentors),
    • Conduct company tours (BIOBus),
    • Provide faculty (including counselors) professional development.
  • BIOBus Tour of South San Francisco
    • Skyline College and Carlmont High School sponsored a BIO-Bus Tour of the South San Francisco Biotechnology Industry.
    • Twenty-seven Carlmont Students, toured a circular route through the area with stops at Genentech and Cell Genesys for on-site tours.
    • The tour ended at Skyline College with activities in the new Science Facilities and lunch in the new Student and Community Center.
    • Skyline faculty led experiments to provide the students with experiential learning in biotechnology.
  • Curriculum Support
    • Text
      • Biotechnology: Science for the New Millennium, Ellyn Daugherty
    • Biotech Education Groups (workshops)
      • County (Gene Connection, SCCBEP etc.)
      • Regional (BABEC)
      • National (Bio-link, BIO etc.)
    • On the web
      • bio-link.org, accessexcellence.org, biospace.org, bio.org
    • Consultant
      • Ellyn Daugherty AEEDaugher@aol.com
    • Ellyn Daugherty
    • Founder of the San Mateo Biotechnology Career Pathway (SMBCP) and recipient of The Biotechnology Institute’s first National Biotechnology Teacher-Leader Award , has been teaching from the Biotechnology: Science for the New Millennium in her SMBCP courses for ten years. Teachers throughout the country have used her model program to launch Biotechnology programs in their schools .
  • Financial Support
    • School (Dept. Staff Dev., PTA, Boosters, Principal)
    • District (Grant Writer)
    • State (Specialized Secondary Program -SSP, SB70)
    • National (NSF, NIH)
    • Industry (Applied Biosystems, Alza, VWR)
    • Private (Peninsula Community Foundation)
  • 4 Major Projects In CBCP
  • 1. Stock Project
    • Students conduct research and invest $1,000 in a minimum of two Biotechnology companies.
    • Weekly, students check progress of stock.
    • Students may sell and buy new stock after 60 days.
    • Final project is a PowerPoint presentation to the class explaining:
      • Stocks Price Per Share as it changed over time.
      • Stocks Total Value Per Share over time.
      • Reasons for fluctuation in the stocks.
  • Stock Summaries of Genentech, Gene Logic, Chiron, and Biogen
  • Genentech
    • biotechnology company
    • that discovers, develops,
    • manufactures and commercializes biotherapeutics for significant unmet medical needs.
    • 13 biotechnology products in the United States.
    • licenses additional products to other companies
    • product development efforts cover a range of medical conditions: cancer, respiratory disorders, cardiovascular diseases, endocrine disorders and inflammatory and immune problems.
  • Gene Logic Continued…
    • The Stock value per stock when I first bought 129 shares of Gene Logic was $3.71 and after 18 weeks the stock value per share was $3.45 (Decrease of $.26 per share)
    • The total price of the stock went from $478.59 to $445.05
  • Price Per Share for Genentech and Gene Logic for 18 Weeks!!!
  • Total Value of Stocks for Genentech and Gene Logic for 18 weeks
  • 2. Protease Project
    • Students use existing scientific knowledge to design an experiment that tests for the presence of protease in unknown samples.
    • Formal lab write-up.
    • Story board (including camera angles, camera person, narrator, actors, etc.).
    • Procedures are filmed in iMovie. Each group of 4 students gets 1 digital camera and 1 iBook.
    • Final experiment is presented in PowerPoint with iMovies converted to QuickTime.
  • You know how protease works. It breaks down proteins. You are going to plan an awesome experiment. With this experiment, you will make millions of dollars. Developing a Protease Assay To protect your money, you need to patent your experiment with the government. However, the government is only accepting experiments that show procedures in movie form.
  • Developing a Protease Assay Objective: (for your group of 4) To design an assay (test) for the presence of protease (protein-digesting enzymes) Materials: Protease (Adolf’s Meat Tenderizer) and 3 unknown samples. Any other chemicals from the lab or grocery store. Include glassware. You list your own materials in this section. Procedures: You design a valid, controlled experiment to test for protease in unknown samples. Make sure your experiment has: 1. Positive and Negative Controls 2. Multiple replications 3. Everything the same in each trial except the variable being tested. 4. “reasonable” volumes and concentrations 5. MEASURABLE DATA
  • 3. "How To" Videos
    • Students work in groups of 4 and choose a scientific concept.
    • Students must review concepts to be taught and write-out a script (Step-by-Step Procedures).
    • Students similarly storyboard project (camera angles, etc.)
    • Students turn in a QuickTime movie for peer review.
    • Fellow students watch one another’s videos and check for scientific inaccuracies.
    • Groups re-film and re-edit to make a final movie.
  •  
  • 4. Product Production Pipeline
    • Working solo and acting as a sales and marketing specialist, a student chooses a biotechnology product they are interested in.
    • Research is conducted, a letter is sent to the company requesting an annual report, and an expert is encouraged to be found on that specific product (contact company, etc.)
    • Students are to become an expert on his/her product and turn in a final PowerPoint presentation to the class.
    • Examples are Roundup Ready Soybeans, Nerve Growth Factors, Pulmozyme, ABD #3948 DNA Synthesizer, etc.
  •  
  • THANK YOU Any Questions? We are all ears. [email_address] [email_address]