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Industrial Biotechnologies China News Sample - Published by CCM International Ltd


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Industrial Biotechnologies China News is a monthly report with 12 issues per annum published by CCM International Limited. It's your gateway to know what is happening in China Market. Key columns …

Industrial Biotechnologies China News is a monthly report with 12 issues per annum published by CCM International Limited. It's your gateway to know what is happening in China Market. Key columns include bio-fuel, bio-produts, bio-based chemicals, bio-materials,etc. If you are interested in this newsletter or ask for the latest sample, please contact or 86-20-38767072.

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  • 1. Industrial Biotechnologies China News Vol.1 Issue 9, 2009 Biotechnologies Copyright © CCM International Limited
  • 2. Industrial Biotechnologies China News Vol.1 Issue 9, Sep. 8, 2009 Industrial Biotechnologies China News 0909 BIO-FUELS ...................................................................... 1 Ready reports related to Lianhai Biotech to expand butanol with new technology...................... 1 industrial biotechnology: SFB expands xanthoceras sorbifolia capacity........................................ 2 - Future of White Biotechnology in China Guizhou launches 10,000t/a biodiesel production line .......................... 4 Edition (2) - Biofuels Market in China – Edition (1) BIO-PRODUCTS .............................................................. 6 - Production and Market of Monosodium Donta Group enlarging yeast production ................................................ 6 Glutamate (MSG) in China Edition (1) Continent Biotech expanding enzyme preparation ................................ 9 - Future of White Biotechnology in China- CAS building largest lactase production base in China ...................... 10 Edition (1) Novozymes expands enzyme production.............................................. 12 - Future of Enzyme in China – Edition (1) Hunan Yuyuan expands in microbial fertilizer ...................................... 14 - Production & Market of Yeast Extract in SK sells SCR enzyme technology to China........................................... 15 China - Edition (1) BIO-BASED CHEMICALS ............................................. 16 China’s citric acid export volume up but price down........................... 16 Coming reports related to VC export price rises ............................................................................... 17 industrial biotechnology: Jianding Biotechnology established...................................................... 19 - Future of Green Biotechnology in Baolingbao to develop FOS and dietary fiber ....................................... 21 China - Future of Red Biotechnology in China BIO-MATERIALS ........................................................... 23 - Lactic Acid Bacterium Industry in Shenzhen Ecomann launches 5,000t/a PHA.......................................... 23 China Tiancheng Corn to carry out PLA project.............................................. 24 - Future of Starch in China NEWS IN BRIEF............................................................. 25 - Future of Enzyme in China – Edition China holds 2009 summit forum on microbial fertilizer ....................... 25 (2) Green Energy Group invests in biodiesel.............................................. 25 - Production and Market of Yeast in Asia Laibin Tianren launches160,000t/a biofertilizer plant........................... 26 Pacific Rim China to cultivate large-scale energy forests........................................ 26 Ministry of Health approves 26 food additives...................................... 26 CCM related newsletter: Beijing founds biogas technology strategic alliance ........................... 26 - Corn Products China News Guangzhou establishes biotechnology service alliance ..................... 26 Nanyang Tianrong builds 6,000t/a PPC catalyst ................................... 26 Sichuan Guanghe to build 100,000t/a sweet potatoes ethanol ........... 26 Contact us for more information about CCM. Copyright CCM International Ltd. Email:
  • 3. CCM Newsletter Industrial Biotechnologies China News Headlines of Industrial Biotechnologies China News 0909 ■ Lianhai Biotech will expand butanol production Editor’s Word based on its new technology. Welcome to September Issue of Industrial Biotechnologies China News ■ Guizhou launched a 10,000t/a bio-diesel published by CCM International, a professional consulting company who has production line on Aug. 6th 2009. been intently focusing on dynamics of China’s industrial biotechnologies industry. ■ Shuangfeng Forestry Bureau is expanding XS production capacity in Yichun City. Growing concerns on environmental protection and energy security have ■ Donta Group is to launch its yeast expansion become key drivers for China’s fast growing industrial biotechnology. Successive project by the end of Sep. 2009. supporting policies are clear indicators showing China’s determination to develop ■ Continent Biotech is building a 15,000t/a enzyme this industry----On June 2nd, 2009, China's State Council announced a policy preparation plant. package to accelerate bio-industry development; ---during Aug. 2009, some local ■ Novozymes will construct an enzyme production governments like Shandong and Shenzhen issued their own plans; ----Also, in base in Tianjin. the 11th Five-Year Plan (2006-2010), Chinese government has proclaimed to ■ CAS is building a lactase production base in promote biodegradable materials. Jiangxi, aiming to capture China’s huge lactase market. Attracted by its huge potential, enterprises both domestic and overseas have ■ Hunan Yuyuan signed a capital increase displayed strong interests in bio-industry. For example, Shenzhen Ecomann’s agreement with Shenzhen Fortune Venture in order investment in PHA and Tiancheng Corn’s in PLA, the two promising materials to expand. from renewable resources, covered in this issue are both evidences ■ SK Holding sold SCR enzyme technology to China demonstrating the trend. Besides, Novozymes’ global strategy on enzymes Power in late July 2009. expansion covered indicates a global trend for second-generation bio-ethanol. ■ In the first seven months of 2009, VC export price has climbed and may keep growing. Besides, under recovering global economy and growing environmental protection ■ Jianding Biotechnology plans to launch its awareness worldwide, more players domestic and overseas are expected to first-phase glucosamine and activated carbon increase investment in China’s biotechnology sector. production lines by the end of this year. ■ Baolingbao plans to enter FOS and dietary fiber Main companies and institutes mentioned in this issue market through getting listed on Shenzhen Stock Exchange. ■ China’s citric acid export volume has climbed up with price fall in the first seven months of 2009. ■ Shenzhen Ecomann launched a 5,000t/a PHA production line in Shandong. ■ Tiancheng Corn is planning to construct 10,000t/a PLA with several production lines. Copyright CCM International Ltd. Email:
  • 4. CCM Newsletter Industrial Biotechnologies China News BIO-FUELS Lianhai Biotech to expand butanol with new technology Jiangsu Lianhai Biological Technology from flour deep-processing as raw this expansion project is divided into Co., Ltd. (Lianhai Biotech) will produce material. three phases (TABLE 1). butanol on a large scale by adopting fermentation method using wastewater With total investment of USD400 million, TABLE 1: Information of the project Item Investment (USD) Capacity (t/a) Launch time First phase 60 million 35,000 Sep. 2008 Second phase N/A 100,000 Oct. 2009 Third phase N/A 200,000 Mar. 2011 Source: CCM International The core technology adopted in this industry domestic market. expansion project uses the patented To achieve energy conservation strain technology from Shanghai and consumption reduction; At present, there are eight domestic Institute for Biological Science (SIBS) of To achieve recycling and clean enterprises producing butanol by Chinese Academy of Sciences (CAS), production; fermentation, among which Jilin Ji’an and is jointly developed b y Lianhai To promote Lianhai Biotech to be Biochemical Co., Ltd. (Jilin Ji’an) is the Biotech and Jiangnan University. the largest butanol producer at biggest one with the capacity of According to CAS and experts from home. 50,000t/a, and another three, namely China's fermentation industry, the Jiangsu Jinmaoyuan Biochemical Co., technology has reached international The project has been declared as a Ltd. (Jiangsu Jinmaoyuan), Guangxi advanced level. major provincial project of transferring Guiping Jinyuan Alcohol Co., Ltd. scientific & technological achievements. (Guiping Jinyuan) and Jilin Cathay By adopting this new technology, this And in early Aug., it has passed the Industrial Biotechnology Co., Ltd. (Jilin project will make the following major online assessment by the experts from Cathay) (FIGURE1), has capacity of breakthroughs: Provincial Science and Technology 30,000t/a for each. To achieve recovery of wastewater Department. Upon completion, butanol from flour deep-processing supply will become relatively sufficient in 1 Copyright CCM International Ltd. Email:
  • 5. CCM Newsletter Industrial Biotechnologies China News FIGURE 1:Capacity of domestic butanol enterprises in 2008 60,000 50,000 50,000 40,000 (Unit: t/a) 30,000 30,000 30,000 30,000 20,000 10,000 5,000 5,000 5,000 5,000 0 Jilin Ji'an Jiangsu Guiping Jilin Cathay Jilin Zhonghai Heilongjiang Tangshan Tongliao Jinmaoyuan Jinyuan Haocheng Jidong Zhongke Tianyuan Source: CCM International Note: Jilin Zhongha: Jilin Zhonghai Chemical Co., Ltd. Heilongjiang Haocheng: Heilongjiang Haocheng Chemical Co., Ltd. Tangshan Jidong: Tangshan Jidong Solvent Co., Ltd. Tongliao Zhongke Tianyuan: Tongliao Zhongke Tianyuan Starch Chemical Co., Ltd. Domestic butanol supply has been enterprises plan to expand their producers. However, butanol application falling short of demand, with the output production capacity. And annual is expected to become an irreversible 50% less than the consumption. From increased capacity of the butanol trend, given the potential pressing 2000 to 2006, domestic butanol projects will reach 730,000 tonnes. situation of oil resources depletion and consumption had increased year by Through continuous project expansion, the expected price rise of oil, so butanol year, and in 2006, the consumption China will be able to reverse the fermentation industry is sure to become reached 7,400,000 tonnes at home. dependence on imports. promising. Meanwhile, the butanol prices have risen from about USD1,318/t in Jan. in Although crude oil prices has dropped to 2006 to USD2,342/t at present. below USD50/barrel caused by financial crisis since H2 2008, which had led to Currently, some domestic butanol production suspension of many butanol SFB expands xanthoceras sorbifolia capacity Shuangfeng Forestry Bureau (SFB, biggest bio-energy production base in initiated since 2008, which is expected located in Yichun City, Heilongjiang Heilongjiang upon completion. to be launched by the end of 2010. The Province) is building a xanthoceras second phase with 266 hectares XS is sorbifolia (XS) base in Yichun City, This XS base construction is divided being built at present and will be which is expected to become the into two phases. The first-phase launched by the end of 2012. In fact, construction with 133 hectares XS has SFB has planned to expand its XS 2 Copyright CCM International Ltd. Email:
  • 6. CCM Newsletter Industrial Biotechnologies China News capacity to 1,000 hectares in the next XS (PICTURE) is an ideal raw material no environmental pollution parameter five years. for biodiesel and bioethanol production like sulfur and nitrogen, etc, which with its high oil content, with seed oil conforms to the quality indexes of Insider reveals that after the launch of content of about 30%-36% and kernel biodiesel. Since 2005, China has this XS base, it will supply XS for China oil content of 50%-70%. Besides, it has successfully developed the technology Nature Petroleum Company (CNPC) as high output of about 1,500-2,000kg/h. to produce biodiesel with XS as raw the raw material for biodiesel or Moreover, it is said that biodiesel material. bioethanol production. produced from XS has about 93.4% hydrocarbons with 18 carbons and has PICTURE: Cross-section of XS Source: At present, there are about 5,300 for carbon content in biodiesel. Those However, raw material cost is too much hectares XS in China, mainly distributed biodiesel producers using waste animal for producers using high oil content in four provinces – Shanxi, Inner oil and vegetable oil as raw material plant to produce biodiesel (TABLE 2), Mongolia, Liaoning and Shaanxi. And were seriously affected by this standard which is a bottleneck for their some other provinces like Gansu are and some even went bankrupt. The development. For example, Sichuan also trying to cultivate this plant, and quality of biodiesel produced from waste Gushan Oil Chemical Co. Ltd. (Sichuan Chinese Academy of Forestry has animal oil and vegetable oil varies a lot, Gushan) produces biodiesel by using provided great support to these areas which can do harm to machines. soybean or colza with capacity of by popularizing the XS planting 240,000t/a, and the cost on raw material technology, aiming to provide ample raw This standard has driven biodiesel has seen continuous increase, thus material for biodiesel production in the producers to actively search for some hindering the development of biodiesel, future. Currently, most of XS are used in high oil content plants as raw materials. according to Mr. Zhao, president of edible oil, medicine, etc, in China. Guizhou, for instance, had launched a Sichuan Gushan. 10,000t/a biodiesel production line with Chinese government enacted a jatropha as raw material this month. ‘National standards for biodiesel ‘in 2008, which requires a higher demand 3 Copyright CCM International Ltd. Email:
  • 7. CCM Newsletter Industrial Biotechnologies China News TABLE 2: Main biodiesel producers in China and their raw materials Company Raw material Sichuan Gushan Soybean or colza. Liuzhou Minghui Biofuels Co., Ltd. Jatropha, tung, tea plant Longyan Zhuoyue New Energy Development Co. Ltd Waste animal oil and vegetable oil Source: CCM International XS can be planted in a barren land, production capacity has reached which is easy for mass production. As As estimated, the demand for biodiesel 3,000,000 tonnes in 2008, while actual non-staple food, XS price is expected in China will increase a lot in the near output was only 300,000 tonnes, be less influenced by price fluctuation of future due to global energy shortage. indicating a huge development other products like agricultural products, The prices of petroleum products have potential. industrial products, etc, which will increased for 24 times in 2009, driving contribute to development of XS-based the government to make more efforts to biodiesel. seek new energies. Besides, biodiesel Guizhou launches 10,000t/a biodiesel production line Guizhou has launched the first-phase Academy of Sciences, and all indexes biodiesel project takes Jatropha as raw 10,000t/a biodiesel production line in of the samples have reached the material and is divided into three phases. New Material Industrial Park (Guiyang National Biodiesel BD100 standards. Upon completion of the three phases City, Guizhou Province) on Aug. 6th (TABLE 3), the total capacity will reach 2009. Invested by the No.061 Base of China 160,000t/a. Aerospace Science & Industry Currently, the first biodiesel samples of Corporation (located in Guizhou), a this project have been sent for test by large scientific research and production Guangzhou Energy Institute of Chinese center for aerospace products, this TABLE 3: Information of the biodiesel project Phase Investment (USD) Planned capacity (t/a) Launch time First phase 4,390,000 10,000 2009 Second phase 7,320,000 50,000 2010 Third phase N/A 100,000 2012 Source: CCM International The successful launch of Guizhou’s Autonomous Prefecture of Qianxinan in cultivation, and through scientific 10,000t/a biodiesel line is based on the southwest Guizhou, as well as the cultivation, the average per- hectare following advantages. valleys of Nanpan River, Beipan River, yield of fruit can reach 4,500 kilograms, Red River and Duliu River. which can produce about 100 to 200 First of all, Guizhou is rich in biological kilograms biodiesel. Using Jatropha as resources. There are abundant wild What’s more, there are many barren the main raw material for biodiesel Jatropha resources in Bouyei-Miao mountains suitable for Jatropha production can not only reduce 4 Copyright CCM International Ltd. Email:
  • 8. CCM Newsletter Industrial Biotechnologies China News production cost, but also increase the At present, some domestic and foreign Oil Corporation (CNOOC) will invest in local peasants’ income and prevent land energy companies also concern about Hainan and Sichuan, and British desertification. the potential development of Jatropha in Sunshine Technology Group, a China, and have invested in Jatropha commercial forestry plantation company, Besides, local market prospect of cultivation. For example, PetroChina cooperates with the Honghe Prefecture biodiesel is expected to be bright, as Limited (Petrol China), the biggest Forestry Bureau of Yunnan Province to there are many mining companies in controlled subsidiary of China National jointly develop Jatropha base. Guizhou and diesel is greatly needed in Petroleum Corporation(CNPC), plans mining operation. to invest in Jatropha production base in Yunnan, and China National Offshore PICTURE: Distribution of Jatropha bases Main Jatropha planting regions Minor Jatropha planting regions Source: CCM International At present, there are dozens of biodiesel capacity has reached demand is estimated to reach biodiesel enterprises including private, 3,000,000t/a in 2008, the actual annual 20,000,000 tonnes by 2010 in China. In join stock and state-owned enterprises. output is only 300,000 tonnes, indicating view of the huge gap between the Hebei Zhenghe Co., Ltd., Sichuan a huge development potential. supply and the demand, related Gushan Group Co., Ltd. and Fujian enterprises are expected to seize the Zhuoyue Co., Ltd. are relatively larger By 2010, China’s annual biodiesel market opportunity and speed up the enterprises with annual output of above output will reach 1,000,000 tonnes, and biodiesel investment (FIGURE 2). 10,000 tonnes. Although China’s 9,000,000 tonnes by 2020. And the 5 Copyright CCM International Ltd. Email:
  • 9. CCM Newsletter Industrial Biotechnologies China News FIGURE 2: Capacity of major biodiesel producers in 2008 250,000 240,000 200,000 150,000 100,000 (Unit: t/a) 100,000 50,000 50,000 50,000 30,000 12,000 10,000 10,000 6,000 0 Sichuan Liuzhou Longyan Xiamen Hebei Heibei Jiangsu Guizhou Shanxi Gushan Minghui Zhuoyue Zhuoyue Zhenghe Fukuan Keyuan Jiangnan Huashuo Hangtian Source: CCM International As an emerging industry in China, to promote its development. National Taxation Supporting Policy for biodiesel is characterized by both great People's Congress has implemented Bioenergy and Biochemical Industry’ development potential and various the ‘Renewable Energy Law’ since 2006, and so on. These policies are expected restrictions in the early stage. Chinese and the Ministry of Finance, National to provide a strong support for domestic government has attached great Development and Reform Commission biodiesel development. importance to the development of and other departments jointly issued biofuels and released relevant policies ‘Advices on Implementing Fiscal and BIO-PRODUCTS Donta Group enlarging yeast production Dongguan Donta Group Co., Ltd. Ltd. (Guangxi Yipinxian) in Laibin City, Donta Group’s yeast expansion project (Donta Group, headquartered in Guangxi Province for its yeast capacity is based on the following advantages. Dongguan City, Guangdong Province) is expansion. expanding yeast production and is Firstly, this project can take the expected to launch its 48,000t/a dried Actually, these two subsidiaries were advantage of adequate raw material yeast and 10,000t/a yeast extract jointly invested by Donta Group, supply in local areas. As the biggest facilities by the end of Sep. 2009. Guangxi Laibin Donta group Co., Ltd. sugar cane production region in China, (Laibin, a local subsidiary of Donta Guangxi has taken up more than 70% of Early in May 2006, Donta Group had Group, established in 2003) and China’s total sugar cane output these established two subsidiaries, Guangxi Lesaffre Group (the world’s biggest years. And Laibin took up 18% of Danbaoli Yeast Co., Ltd. (Guangxi yeast producer), with investment of Guangxi’s total with 8.3 million tonnes in Danbaoli) and Guangxi Yipinxian USD102 million. 2008. Besides, Donta Group has 7 Biochemical Science & Technology Co., sugar processing bases supplying 6 Copyright CCM International Ltd. Email:
  • 10. CCM Newsletter Industrial Biotechnologies China News treacle as common raw materials of exports its products to Southeast Asia, yeast for the new project. Besides, local Middle East, South America, Africa, etc., With fast growth of some local government has been paying much which will provide mature sales companies, China’s yeast market has attention to developing yeast industry by networks for these two new companies. seen intense competitions in recent releasing tax preferential policies for years, thus Lesaffre Group prefer to yeast companies. In addition, there are few yeast seek some cooperators to enlarge its producers in Guangxi, but the market share in China. As the biggest Secondly, this project is equipped with consumption volume is estimated at yeast producer in the world, Lesaffre advanced production technology and 50,000 tonnes per year, indicating a big Group launched a yeast production equipments sourced from Lesaffre market opportunity. base with capacity of 3,000t/a in Anhui Group, who has been producing yeast Province of China in 1999, and then it for 150 years. With the strong technical This cooperation can achieve a win-win built a sales company in Shanghai in support from Lesaffre Group, the new situation. Donta Group wants to bring in 2002. facilities are expected to make the best new advanced technology for deeper use of the advanced equipments. development in yeast field, and Lesaffre In 2008, China’s total yeast production Group intends to expand its market capacity reached 190,000t/a, Besides, Donta Group has a subsidiary share in China and cut down the accounting for nearly 20% of the world’s named as Guangdong Danbaoli Group production cost with local rich raw total capacity, and the actual total output Co., Ltd. (Guangdong Danbaoli) with material supply and large sales network reached 100,000 tonnes. It is expected current dried yeast capacity of 16,000t/a, of Donta Group, according to Mr. Guo, that, as some producers are expanding which has strong sales network technical engineer of Guangdong production, the total yeast capacity will throughout China and extensively Danbaoli. reach 210,000t/a in 2009 (FIGURE 3). FIGURE 3: China’s total yeast capacity, 2005 ~ 2009est. 250,000 210,000 200,000 190,000 170,000 150,000 150,000 (Unit: t/a) 120,000 100,000 50,000 0 2005 2006 2007 2008 2009est. Source: CCM International 7 Copyright CCM International Ltd. Email:
  • 11. CCM Newsletter Industrial Biotechnologies China News Besides, yeast industry is becoming accounting for over 70% of China total put great efforts to expand their more and more concentrated in China capacity. In recent years, the top 2 have capacity. with the top 3 players (TABLE 4) TABLE 4: Major yeast producers in China, 2009 Manufacturer Location Capacity ’08 Hubei Angel Yeast Co., Ltd. Xinjiang, Shandong, Inner Mongolia, Henan, Guangxi and Hubei 91,000 Mauri Yeast Heilongjiang, Hebei, Shandong, Guangdong, Xinjiang 30,000 Guangdong Danbaoli Yeast Co., Ltd. Guangdong 16,000 Guangdong Zhuhai Aoli Yeast Co., Ltd. Guangdong 2,000 Anhui Lesaffre (Mingguang) Anhui 3,000 Shandong Yantai Hongde Food Industry Co., Ltd. Shandong 2,000 Guangdong Jiangmen Center for Biotech. Co., Ltd. Guangdong 4,000 Shandong Xiwang Leavening Co., Ltd. Shandong 1,500 Qiqiha’er Longtai Food Co., Ltd. Heilongjiang 1,500 Source: CCM International PICTURE: Distribution of major yeast production regions in China Source: CCM International In addition, in recent years, China’s estimated, the major potential market dry yeasts, showing a huge market demand for yeast and yeast extract has for yeast in China is rural areas, where potential. been increasing year by year attributed about 90% of homemade flour products to the development of related industries except sour dough do not apply active Donta Group is a state-owned like feedstuff and flour products, etc. As enterprise established in 1935, and has 8 Copyright CCM International Ltd. Email:
  • 12. CCM Newsletter Industrial Biotechnologies China News a raw sugar processing base with conglomerate with 21 factories and series of products, namely sugar, processing capacity of 700,000t/a, companies located in 4 provinces - biological engineering, thermal-electric which provides part of molasses for Guangdong, Guangxi, Shanxi, Yunnan, power and paper-making. Guangdong Danbaoli. As a Donta Group is mainly engaged in four Continent Biotech expanding enzyme preparation Continent Biotech Group Co., Ltd. xylanase will remain the company’s key Continent Biotech has been paying (Continent Biotech, headquartered in products. great attention to after-sales service for Qingdao City, Shandong Province) is clients both at home and abroad. It built now constructing a 7,000t/a solid Actually, Continent Biotech is the first a biotech research institute in Shandong enzyme preparation production line, the enzyme producer at home to in 2005, for the sake of developing second phase of its 15,000t/a enzyme industrialize liquid enzyme spraying market-target and high-quality feed preparation plant, in Weifang City, uniformity technology which is enzyme and supply technology support Shandong Province. developed independently in 2001. By for various clients in clients. applying this technology in its enzyme Continent Biotech’s 15,000t/a enzyme preparation production, reaction In 2008, there were over one hundred preparation plant consists of the temperature can keep below 60℃ thus feed enzyme producers in China with first-phase 8,000t/a for liquid enzyme maintaining high enzyme activity, as in relatively small production capacity and preparation, which was completed on normal reaction temperature would low-quality products, except Jul. 20th 2009 with investment of surpass 60℃ with enzyme activity Novozymes (China) Biotechnology Co., USD12 million, and the second-phase losing largely. Ltd, the largest enzyme producer in the 7,000t/a for solid enzyme preparation world. Owing to lack of strong market with investment of USD22 million. Upon Besides, with this technology, Continent competitiveness, in terms of technology completion of this plant, Continent Biotech has built another two liquid feed and capitals, many domestic Biotech will expand its total enzyme enzyme production bases respectively small-scale feed enzyme producers preparation capacity to 20,000t/a, and is in Binzhou City with 3,000t/a complex choose to stop or suspend expansion, expected to become the largest enzyme enzyme and Linyi City with 1,000t/a except Continent Biotech and preparation producer in Shandong. phytase and 1,000t/a xylanase in recent Guangdong VTR Bio-tech Co., Ltd., years. both of which continue capacity Early in Aug. 2008, Continent Biotech expansion. The latter in July launched a has begun to construct this 15,000t/a According to Mr. Duan, technical 20,000t/a feed enzyme base in Inner enzyme preparation plant in Weifang. At engineer of Continent Biotech, enzyme Mongolia. present, the company has constructed products produced by this technology one major workshop with 240 m3 have been accepted by users because The demand for feed enzyme will fermentation capacity, one distilling of its high quality and short supply. In continue to rise in the future in China, as workshop and two power workshops. In 2008, Continent Biotech’s sales network more and more feedstuff producers this plant, Continent Biotech will has spread throughout China, even to realize that feed enzyme can greatly produce various enzyme preparations some other countries in Asia like Japan, enhance utilization rate of nutrition in like feed enzyme, edible enzyme and Philippines, etc. , and its sales value feed, which can efficiently decrease industrial enzyme etc. But feed reached about USD44 million. production cost. Given this trend, feed enzymes like phytase, alkaline pectase, enzyme is expected to be widely used in liquid complex enzyme and alkaline animal feedstuff. Moreover, increasing 9 Copyright CCM International Ltd. Email:
  • 13. CCM Newsletter Industrial Biotechnologies China News feedstuff output in China year on year is feed enzyme preparation (FIGURE 4). another key driver for increasing use of FIGURE 4: Feedstuff output in China, 2005~2009 160 140 (Unit: million tonnes) 120 100 80 60 40 20 0 2005 2006 2007 2008 2009 est Source: CCM International Meanwhile, increasing numbers of feed enterprises. Actually, feed enzyme enzyme, probiotics, protein, bio-fertilizer, enterprises expect to cooperate with producers should develop new allicin and so forth. The company is feed enzyme producers, based on technology to improve the quality of equipped with the most advanced liquid high-quality feed enzyme and good products, thus increasing and solid-state fermentation facilities in after-sales service. In this situation, feed competitiveness in the future. the world and ascends into the leading enzyme producers taking advantage of large-scale biological preparation and high-quality products and good Established in 2001, Continent Biotech manufacturing enterprises. after-sales performance can resolve is composed of six manufacturing various production difficulties for feed enterprises and mainly engaged in CAS building largest lactase production base in China Chinese Academy of Science (CAS) Jiangxi Province, aiming to capture stages, consisting of seven production established a subsidiary Chinese China’s huge lactase market. lines. Upon completion, CASL will Academy of Science Lactase Co., Ltd. achieve 3,000t/a lactase capacity th (CASL) on Aug.18 , 2009, and started With total investment of USD19.02 (TABLE 5). to construct China’s biggest lactase million, the construction of this production base in Dean County, production base is divided into two TABLE 5: Information of CASL’s new project Item First phase Second phase Capacity 1,500t/a 1,500t/a Investment USD11.7 million USD7.32 million Start time Aug. 2009 Oct. 2010 Launch time 2010 2011 Source: CCM International 10 Copyright CCM International Ltd. Email:
  • 14. CCM Newsletter Industrial Biotechnologies China News Lactase, also named as lactase, which can rapidly and efficiently and inefficient technology, thus leading beta-galactosidase (β-galactosidase), hydrolyze lactose to glucose and to small profit, given the adverse normally exists in human body in galactose with 6,000u/g, compared with situation of economic downturn at that intestinal epithelial cells, thereby 3,000u/g or 5,000u/g for existing time. Owing to domestic insufficient contributing to digestion of lactose products. supply but huge demand, 98% of present in dairy foods. However, large China’s lactase is imported from other numbers of people in Asia and Africa, At present, China has few lactase countries like US and Japan, etc., as accounting for 70% of Asia and Africa’s producers, and most of them have small estimated. total as estimated, have a genetic capacity. As reported, the total lactase deficiency of this enzyme and are production capacity in China was only Thanks to increasing demand for low unable to digest lactose. 20t/a in 2008. For example, Harbin lactose milk products, the demand for Meihua Biotechnology Co., Ltd. (Meihua lactase in China has been increasing in The new base will adopt the technology Biotechnology), the only active producer recent years. It was estimated that of using thalli Mutated Aspergillus Niger in China currently, has lactase capacity Chinese demand for lactase was about to produce lactase developed by CAS in of only 8t/a. 2,700 tonnes in 2008, most of which 2006, which can enhance lactose was imported from overseas at price of hydrolysis efficiency and cut down the According to Mr. Zhang, salesman of about USD59,000/t, higher than that of production cost compared to using the Meihua Biotechnology, some USD43,000/t in domestic market other thalli under the same condition. companies stopped lactase production (FIGURE 5). Besides, it will mainly produce a new in 2008 due to its high production cost FIGURE 5: Output of lactose milk products and demand for lactase in China, 2005~2008 3,500,000 3,000 2700 3,000,000 3,000,000 2300 2,500 2,500,000 2000 2,500,000 1800 2,000 Unit: tonne 2,000,000 2,000,000 1,850,000 1,500 1,500,000 1,000 1,000,000 500,000 500 0 0 2005 2006 2007 2008 Lactose milk products Lactase Source: CCM International For the sake of better lactose absorption Yang, Deputy Secretary General of 92%, implying promising market for low when consuming dairy products, many Chinese Nutrition Society, the lactose milk, as well as a huge demand countries add lactase to dairy foods or proportion of Chinese adults suffering for lactase to decompose lactose for other dairy meals. According to Ms. from lactose intolerance is as high as reasonable nutrition absorption. 11 Copyright CCM International Ltd. Email:
  • 15. CCM Newsletter Industrial Biotechnologies China News Novozymes expands enzyme production Novozymes, the world’s biggest Area and expects to launch it by 2010. After the launch of this new base, with industrial enzymes producer, Through this expansion, Tianjin total investment of about USD53 million announced on Aug. 3rd 2009 that it will Novozymes will become Novozymes’ and coverage area of 5,599m2, construct an enzyme preparation third global enzyme production base. Novozymes is predicted to double its production base in Tianjin enzyme preparation capacity in China Economic-Technological Development (FIGURE 6). FIGURE 6: Main enzyme producers’ market share in the world 22% 47% 6% 21% 4% Novozymes BASF Danisco DSM Others Source: Novozymes’ annual report, 2007 According to Mr. Ren, senior manager agro-forestry wastes as a large fields since 1998 (FIGURE 7). And after from Asia Bioenergy Department of agricultural country. Also, Novozymes nearly 10 years’ research and Novozymes, the company is very predicts that the second generation development, it has solved some major optimistic about China’s future bioethanol consumption will explosively technical obstacles in development of the second generation grow in 2012. second-generation bioethanol bioethanol, namely using crop wastes production process, and is expected to as raw materials, as China highly Novozymes has been producing various produce second bioethanol enzymes on concerns about energy supply and enzymes that are widely used in food, a large scale in 2010. security and has abundant supply of brewing, washing and other industrial FIGURE 7: Novozymes enzyme annual sales, 2004~2008 1,600 1,200 (Unit: million USD) 800 400 0 2004 2005 2006 2007 2008 Source: CCM International 12 Copyright CCM International Ltd. Email:
  • 16. CCM Newsletter Industrial Biotechnologies China News Enzymes production cost is an crop wastes to produce fuel ethanol on more and more attention to important factor influencing the a large scale. second-generation bioethanol. On July development of second-generation 9th 2009, the enzyme preparation bioethanol production. At present, The second-generation bioethanol has branch of China Fermentation Industry enzyme preparation cost accounts for a long value chain, including raw Association held a discussion in 35% of total production cost for material collection, transport and Qingdao. Over twenty domestic large second-generation bioethanol storage, as well as cellulosic ethanol biotechnology enterprises and research production, and after large-scale production, sales and so on, among institutes attended the meeting industrialization, the cost proportion will which the cellulose technology can (FIGURE 8). The branch president be reduced to 20-25%. According to reduce production cost largely. And the announced the development plan of the Novozymes’ estimation, the breakthrough of this technology needs enzyme preparation industry. Although second-generation bioethanol multilateral collaboration to achieve a domestic biotechnology enterprises production cost in China will be mutual development. Novozymes and have made rapid progress in recent USD2.59 per gallon in 2010, and can be COFCO in early 2009 reached a new years, their enzyme annual output is still reduced to USD1.5 per gallon by 2015, cooperation agreement with Sinopec to much less than multinational which will be very competitive compared initiate large-scale commercial enterprises’. with gasoline price (USD2 per gallon). production by using crop wastes as raw materials to produce second-generation According to Mr. Steen Riisgaard, CEO bioethanol. of Novozymes, there is only one step away for the company to make use of Chinese government has been paying FIGURE 8: Major enzyme producers’ capacity in 2008 10,000 8,000 8,000 6,500 6,000 6,000 (Unit: t/a) 4,000 4,000 2,000 0 Hunan Jinshi Zhengzhou Jiangyin Henan Yangshao Fuyuan Baishenglong Source: CCM International Note: Hunan Jinshi Group Co., Ltd. Zhengzhou Fuyuan Biotechnology Co., Ltd. Jiangyin Baishenglong Bioengineering Co., Ltd. Henan Yangshao living to turn the engineering Co., Ltd. 13 Copyright CCM International Ltd. Email:
  • 17. CCM Newsletter Industrial Biotechnologies China News Hunan Yuyuan expands in microbial fertilizer Hunan Yuyuan Bio-technological Co., opportunities for microbial fertilizer potassium and phosphate and fix Ltd. (Hunan Yuyuan, located in Hunan manufacturers. nitrogen, but also can greatly increase national bio-industry base Changsha fertilizer utilization rate, so it is City, Hunan Province), a leading Compared with common fertilizer, increasingly favored by farmers. enterprise of microbial fertilizer industry, microbial fertilizer has advantages in signed an agreement with Shenzhen ecological protection, crop quality Fourthly, microbial fertilizer has a large Fortune Venture Capital Co., Ltd. improvement and fertilizer efficiency profit margin, compared with common (Shenzhen Fortune Venture) to obtain enhancement, as microbial fertilizer can fertilizer. And currently, only a few have capital for capacity expansion and R&D increase beneficial bacteria in soil to been engaged in microbial fertilizer strengthening on Aug. 21st 2009. help crops use nutrients. According to production, and thus they have huge Fertilizer Testing Center of Ministry of development potential to capture market Actually, after establishment, Hunan Agriculture, farm products output can share amid this less intense market Yuyuan had invested about USD15 increase 12% ~20% by using microbial competition. The large formal million to build a 10,000 t/a.microbial fertilizer. So in vegetable growing manufacturers, in particular, like Hunan fertilizer production line. This production regions like Shouguang, farms use Yuyuan, are expected to work hard and line has the largest investment and microbial fertilizer more and more make great progress on this field, largest production capacity, and its widely. depending on their sufficient funds and technical level and equipment are the strong scientific and technological most advanced in China. And currently, Furthermore, the average utilization rate background. As for other small it has putt high concentrations of of common fertilizer is only 20%~30%, companies, like family workshops, they bacteria powder into commercial mass while that of microbial fertilizer is more are running on a small scale and weak production. higher , for example, the nitrogen fixed in competitiveness. in rhizobia can almost all be absorbed Hunan Yuyuan’s expansion of microbial by plants. Currently, there are more 500 microbial fertilizer is attributed to at least four fertilizer companies in China (TABLE 6), reasons. More and more farmers realize annual output is about 5 million tonnes, important role of microbial fertilizer in and the application areas are nearly 6 Firstly, Chinese government has practical production, so microbial million hectares. Microbial fertilizer formulated some policies to promote the fertilizers have become more and more product categories continue to increase, extensive use of microbial fertilizer. For popular than common fertilizers with so far, the products registered in the example, the first document release by farmers. Ministry of Agriculture are divided into Chinese government this year stipulate two major categories of antimicrobial to strengthen the protection and Thirdly, the current status of the soil and microbial fertilizer including 11 improvement of soil, and to promote and gives business opportunities to varieties. In the next five years, China's the use of microbial fertilizer in the microbial fertilizer manufacturers. The microbial fertilizer annual output is whole country. soil compaction and salinization have expected to reach 8 million ~ 10 million become widespread, as farmers have tones. And it is expected that microbial Secondly, some farmers have begun to been using nitrogen fertilizer for a long fertilizer industries will play a more accept and use microbial fertilizer, time. Compared with common fertilizer, important role in agricultural production. which has brought tremendous microbial fertilizer not only can break 14 Copyright CCM International Ltd. Email:
  • 18. CCM Newsletter Industrial Biotechnologies China News TABLE 6: Some domestic microbial fertilizer companies in 2008 Company Capacity (t/a) in Location Hebei Fuhua Kangtute Environmental Co., Ltd. 100,000 Shijiazhuang, Hebei Hebei Juwei Biological Engineering Co., Ltd. 100,000 Baoding, Hebei Dezhou Sunshine Biotechnology Co., Ltd. 100,000 Dezhou, Shandong Dalian Shibeide Biotechnology Co., Ltd. 100,000 Dalian, Liaoning Shenyang Shennongren Biochemical Engineering Co., Ltd. 30,000 Shenyang, Liaoning Liaoning Yuanheng Biotechnology Co., Ltd. 30,000 Chaoyang, Liaoning Beijing Wlong Technology Co., Ltd. 30,000 Beijing, Beijing Heilongjiang Suihua Nongken Chenhuan Biology Science & Technology Co., Ltd. 20,000 Suihua, Heilongjiang Shanxi Yi’an Biological Engineering Co., Ltd. 5,000 Yuncheng, Shanxi Beijing First Biological Engineering Co., Ltd. 5,000 Beijing Source: CCM International Although, due to the financial crisis in economy see rapid development and will increase the demand for microbial 2008, market demand for microbial increase in per capita income, Chinese fertilizer. Meanwhile, the new industry fertilizer production has experienced government will increase the system will also prompt domestic weak growth. In the long run, with the investments in microbial fertilizer, which microbial fertilizer industry to reshuffle. SK sells SCR enzyme technology to China SK Holding Co., Ltd. (SK Holding, agreement with Germany-based EnBW chemistry catalysts technology headquartered in Seoul, South Korea) Group in July 2007 and began to commonly adopted in China, which sold its Selective Catalytic Reduction explore the overseas markets. uses chemicals like vanadium pentoxide (SCR) enzyme technology to Qingdao and titanium dioxide as raw materials to Huatuo Technology Co., Ltd., a Insider reveals that SK Holding will deal with pollutants of nitrogen oxide subsidiary of China Power Investment cooperate with more companies to and sulphur dioxide, etc, SCR enzyme Company (China Power) in late July promote this enzyme technology in technology has higher catalysis 2009, which will enable China Power to power plants and chemical plants and efficiency and lower temperature, and be the first Chinese company to apply enhance its application in China in the can reclaim more kinds of exhaust enzyme technology into industrial near future. emissions, even solid waste. exhaust emissions treatment at home. Based on varieties of Bacillus, SCR At present, there are several kinds of SCR enzyme technology can be used to enzyme technology uses enzyme as exhaust emissions treatment clean up the exhaust emissions like catalysts, which enjoys higher technologies in China, (TABLE 7), such carbon dioxide, sulfur dioxide, carbon purification efficiency, simpler operation as carbon dioxide reclaiming technology, monoxide, etc. Researched by SK and lower cost compared with the other which has played a growingly important Holding since 1996, this technology has exhaust emission treatment role in recent years due to the been successfully used in South technologies in China, thus it’s expected greenhouse effect caused by rising Korea’s power plants after 2003, to be applied in a variety of recycling carbon dioxide emission. But it can only accounting for 20% of the country’s total and waste treatment enterprises. treat one or two kinds of waste gases, market share currently. Besides, SK thus restricting its wider application. Holding signed a cooperation For instance, compared with SCR 15 Copyright CCM International Ltd. Email:
  • 19. CCM Newsletter Industrial Biotechnologies China News TABLE 7: Major exhaust emission technologies in China Technology Main adopters Launch time ZH active carbon adsorbing organic exhaust gases Hangzhou South Environment Protective Coating Equipment 1993 purifying & recycling treatment technology Co., Ltd. Jiangsu Zhongke Energy-Saving Environmental Protection SCR chemistry catalysts technology 2006 Technology Co., Ltd. Carbon dioxide reclaiming technology Chengdu Demei Engineering Technology Co., Ltd. 2001 High-voltage electrostatic trapping technology Gansu Kejin Environmental Technology Co., Ltd. 2002 Phosphorus emission reclaiming technology Yunnan Nanlin Group Co., Ltd. 2008 Source: CCM International With the rising awareness of standard of ‘Absorption Gas Cleaner for which satisfies China’s demand for environmental protection, more and Industrial Emission’, which clearly environmental technologies, is expected more Chinese countries intend to seek stipulates the technical standards for to be accepted by more enterprises. new technologies to reduce pollution. In popular waste treatment devices. 2008, Chinese government issued a Therefore, SCR enzyme technology, BIO-BASED CHEMICALS China’s citric acid export volume up but price down Despite US and EU’s anti-dumping year to 393,616 tonnes in the first seven the same period of 2008 since early duties on Chinese citric acid in 2009, months of 2009 (FIGURE 9). Except to 2009. China’s citric acid export volume has EU and US, export price of citric acid to still kept increasing, up 1.2% year on other countries has slipped largely over FIGURE 9: China’s citric acid export volume, Jan. ~Jul. 2009 80,000 68,707 70,000 62,089 60,624 62,905 60,000 53,910 48,181 50,000 (Unit: tonne) 37,200 40,000 30,000 20,000 10,000 0 Jan-09 Feb-09 Mar-09 Apr-09 May-09 Jun-09 Jul-09 Source: China Customs 16 Copyright CCM International Ltd. Email:
  • 20. CCM Newsletter Industrial Biotechnologies China News Respectively since Jun. 2008 and Sep. importer of Chinese citric acid currently. remained similar to that in H1 2008, but 2008, EU and US have begun to levy sulphuric acid price has plummeted to high anti-dumping duties on China’s key Prices of homemade citric acid exported around USD30/t from USD245/t since citric acid producers like Anhui BBCA to EU and US have stayed at relatively the breakout of global financial crisis. At Biochemical Co., Ltd. and Shandong high level of around USD1,000/t, due to present, sulphuric acid price is still at TTCA etc., which erodes Chinese anti-dumping duties during this period, low level of USD36/t and corn price players’ price advantage in these but export prices to other countries like keeps stable at around USD234/t in markets. Southeast Asia, Africa and South Northeast China. America saw a big drop, ranging from As an export-oriented product, USD680/t and USD820/t, Citric acid export price has kept stable homemade citric acid’s encountering USD100~200/t lower than that in the currently, and it is hard to raise the price anti-dumping sanction from EU and first seven months of 2008. due to current citric acid surplus supply USA has seriously impacted domestic in China. Once both sulphuric acid and citric acid export, because nearly 40% Although Ministry of Commerce corn price rise in the following months, of China’s citric acid export was to EU Administration has executed Export citric acid price may also be pushed up and US before. According to statistics License Administration on domestic slightly in the market. from China Customs, in the first seven citric acid exporters since early 2009, months of 2009, US citric acid import this Export License Administration with China has been the largest citric acid volume from China has decreased by relatively low requirements for domestic producer with total output of around 87.6% and EU import down 28%. citric acid producers couldn’t efficiently 750,000 tonnes per year in the world, restrain pernicious price competition and has exported around 80% of its total However, domestic citric acid producers among them. In order to enlarge market output on average in recent years. have been endeavoring to develop share in oversea markets with no However, its production has been other new and large markets like India, anti-dumping duties, domestic citric acid restrained by the government due to Mexico, Thailand and Indonesia etc. exporters choose to cut down the price. high pollution during citric acid after the anti-dumping duties had been production. implemented. Actually, India has totally Besides, decreasing raw material price imported 32,424 tonnes citric acid from also resulted in price fall of domestic China during the first seven months in citric acid. Corn and sulphuric acid are 2009, up 39% over the same period of key raw materials for citric acid 2008, which makes it the largest production. In H1 2009, corn price VC export price rises Average export price of Vitamin C (VC) Customs (TABLE 8), in the first seven downtrend. The impacts of weak has climbed up in the first seven months months of 2009, VC average export domestic demand have been partly of 2009, continuing an uptrend price has reached USD10,297/t, up offset by the high VC export price. compared to the same period last year. 29.6% compared to the same period last year, while most of the other vitamin According to statistics from China export prices have experienced 17 Copyright CCM International Ltd. Email:
  • 21. CCM Newsletter Industrial Biotechnologies China News TABLE 8: China’s VC export situation, Jan~ Jul, 2009 Item Jan - Jul, 2008 Jan - Jul, 2009 Growth rates (%) Export (tonne) 51,632 47,905 -7.2 Value (USD) 410,165,661 493,274,479 20.3 Average (USD/t) 7,944 10,297 29.6 Source: China Customs The main reasons for VC export price low production cost. rise are as follows: The four biggest domestic VC In recent years, with strong enterprises include (FIGURE 10) Firstly, China has become the world’s competitiveness of China’s VC, some Northeast Pharmaceutical Group Co., VC production base, thus enabling multinational corporations have Ltd (NPC), North China Pharmaceutical domestic VC enterprises to price the gradually stopped VC production. As a Group Co., Ltd (NCPC), China products. result, global dependence on Chinese Shijiazhuang Pharmaceutical Group Co., VC has gradually increased. For Ltd (CSPC) and Aland (Jiangsu) As an important exporter of VC, China example, China VC export volume was Nutraceutical Co., Ltd. (Aland). The VC has strong competitiveness in global VC less than 80,000 tonnes in 2007, but it export prices of these four enterprises market. China produces VC by using increased to 85,239 tonnes in 2008. By all stayed at a relatively high level of two-step fermentation process, which the end of 2008, China VC sales value about USD1,000/t, a big upthrust has reached the world-advanced level had accounted for 86% of total VC sales compared with the same period last and thus being prohibited for export. value in US market. At present, about year, signifying their strong pricing Based on the technology edge, China’s 80% of the world’s VC products are power. VC has good product quality and enjoys sourced from China. FIGURE 10: Capacity of major domestic VC enterprises in 2008 40,000 35,000 30,000 25,000 (Unit: t/a) 20,000 20,000 18,000 10,000 0 CSPC NPC Aland NCPC Source: CCM International Secondly, VC is mainly used in less being affected by economic are not sensitive to the price change of industries of pharmaceuticals, health downturn. And VC only constitutes a VC. food, and food additives, etc. that very small proportion of its downstream provide necessary daily products, thus products’ cost, so downstream clients Thirdly, VC products have seen 18 Copyright CCM International Ltd. Email:
  • 22. CCM Newsletter Industrial Biotechnologies China News excellent sales performance after the promoting the soaring demand of VC. fluctuated slightly in early June. outbreak of H1N1 influenza around the However, to curb the slight price decline world, as VC preparation can effectively In light of huge VC demand and its high this June, the four biggest VC prevent influenza. Besides, many new prices currently (FIGURE 11), the four enterprises decided to stop production kinds of VC composite preparations can VC enterprises had been in full from July to September. As a result, VC also effectively enhance immunity and operation in the first five months this price has risen in July, and is expected prevent influenza, so they had sold well year. With sufficient VC supply in the to maintain uptrend in the near future from last winter to this spring, thus domestic markets, its price only with reduced supply. FIGURE 11: Domestic VC export prices, Jan. – Jul. 2009 10,800 10,600 10,551 10,558 10,400 10,415 10,409 10,202 (Unit: USD/t) 10,200 10,000 10,033 9,903 9,800 9,600 9,400 Jan-09 Feb-09 Mar-09 Apr-09 May-09 Jun-09 Jul-09 Source: CCM International In the long run, VC export price may autumn and winter this year. Secondly, small and medium-sized companies maintain relatively high level, attributed the price of corn, one of VC’s raw plan to produce VC, their products only to the following factors. Firstly, H1N1 materials, may keep at high level sell in domestic market, so their influenza may continue its prevalence because of current severe drought in expansions can not affect VC export for a long time and may break out in the China. Thirdly, although some domestic price. Jianding Biotechnology established Jiangsu Jianding Biotechnology Co., Ltd. Jianding Biotechnology has huge economic and environmental (Jianding Biotechnology), a company independent technology for benefits by reutilizing waste from newly established on Aug. 10th 2009, co-production of glucosamine and production. has initiated the construction of activated carbon. Adopting this first-phase production lines of 3,000t/a technology, glucosamine can be For one thing, glucosamine, as an glucosamine and 12,000t/a activated extracted from citric acid waste, and important health product, is widely used carbon, which will be launched by the then the waste is further processed to as nutritional supplements for articular end of 2009. produce high-quality activated carbon. cartilage treatment, and is the only This technology is believed to create health product approved by the medical 19 Copyright CCM International Ltd. Email:
  • 23. CCM Newsletter Industrial Biotechnologies China News community and nutrition research technology is predicted to have a highly technology can greatly relieve the institutions in US and Europe, for its competitive position in health products environmental pressure. therapeutical effect on bone and joint market as this technology is developed diseases. The market value of independently at home, and the It is thus expected that Jianding glucosamine and its downstream overseas market has not obtained the Biotechnology will have a very important products like health products and technology up to now. position in China’s health product pharmaceuticals is estimated to reach For another, co-production of industry, and will promote China’s USD7 billion. glucosamine and activated carbon can overall health product industry to reduce environmental pollution. With its develop more eco-friendly. Currently, domestic glucosamine activated carbon capacity accounting for production mainly use shrimp shell and more than 1/3 of global total, China is With entry into health products industry crab shell as raw materials, which leads the world’s largest producer of activated in the 1980s, China has rapidly to heavy metal residues and large carbon, a major chemical material with developed in this field in the past amounts of ash contained in annual consumption volume of more decade. By the end of 2007, China has glucosamine products. With than one million tonnes in the world. But approved more than 8,900 varieties of vegetarianism spreading over Europe currently, large quantities of high-quality health products. And more than 1,640 and US, enabling citric acid-based timber and bamboo are consumed at health product manufacturers have glucosamine products to become home to produce activated production achieved total production value of over greatly popular among consumers, every year, leading to high energy USD17 billion annually (FIGURE 12). glucosamine products produced by consumption and severe environmental Jianding Biotechnology using this pollution. Therefore, using this FIGURE 12: Glucosamine output in China, 2002~2007 10,000 9,000 8,000 7,000 (Unit: tonne) 6,000 5,000 4,000 3,000 2,000 1,000 0 2002 2003 2004 2005 2006 2007 Source: CCM International Some enterprises from other industries Corporation to enter health care market. waiting for an opportunity to enter health are very optimistic on the future product industry in China. development of China health product Mr. Wang Dahong, Secretary General of industry. In the end of 2008, , Wuliangye China Health Care Association, said ‘Food Safety Law’ and ‘Rules of Group Co., Ltd., a well-known liquid that some Japanese automobile Supervision and Administration on brand, cooperated with Giant companies with sufficient funds are Health Food Products’ will also promote 20 Copyright CCM International Ltd. Email:
  • 24. CCM Newsletter Industrial Biotechnologies China News integration in health product industry, manufacturers’ competitive landscape in which will change glucosamine China (TABLE 9). TABLE 9:Information of glucosamine manufacturers in China, 2008 Number of Number of Locations Capacity '08, t/a Output '07, t Capacity '08 Output '07 manufacturers, ‘08 manufacturers ‘08 Zhejiang 9 7,150 3,430 33.30% 36.80% 38.00% Jiangsu 9 4,960 2,645 33.30% 25.50% 29.30% Shandong 4 3,110 1,360 14.80% 16.00% 15.10% Fujian 2 3,510 1,320 7.40% 18.10% 14.60% Shanghai 1 350 180 3.70% 1.80% 2.00% Liaoning 1 200 50 3.70% 1.00% 0.60% Jiangxi 1 150 30 3.70% 0.80% 0.30% Total 27 19,430 9,015 100% 100% 100% Source: CCM International Despite facing many challenges, and management enhancement. Capital Co., Ltd. (Top-Bridge Capital) China’s health care products industry is and another two companies, namely expected to have huge development Note: With USD3,000,000 investment, Nantong Foreign Trade Medicines and potential with the rising market demand Jianding Biotechnology was jointly Health Products Co., Ltd. and Jiangsu and continuous technological advances established by Jiangsu Top-Bridge Bochuan Chemical Co., Ltd. Baolingbao to develop FOS and dietary fiber Baolingbao Biology Co., Ltd. oligosaccharide in China. output. Moreover, the two production (Baolingbao, located in Shandong and lines can share parts of the mainly supplies food additive) got listed These two new production lines will both infrastructure, thus reducing the total on Shenzhen Stock Exchange on Aug. adopt membrane filter and enzyme production cost. 19th 2009 with an IPO of 20 million A catalysis methods to produce higher stocks, aiming to raise fund for its purity FOS and water-solubility dietary Also, Baolingbao Biology can promote oligofructose (FOS) and dietary fiber fiber, which can improve the purity from new products with its strong sales production lines. 50% to 80%, insiders revealed. At network, thereby further strengthening present, some Chinese companies have its status as China’s leading prebiotics With total investment of USD39.8 million, begun to use enzyme catalysis method, processor. Currently, it has established Baolingbao will construct production such as Jiangmen Quantum Hi-tech stable business relationships with many facilities of FOS (USD22 million, Biological Engineering Co., Ltd. with large enterprises, including Mengniu, 10,000t/a), a kind of oligosaccharide, current oligosaccharide capacity of Yili, Coca-Cola, etc. Some products and water-soluble dietary fiber 15,000t/a. have major roles in China with a large (USD17.8 million, 30,000t/a). Upon market share. For example, Baolingbao completion of these two projects, Besides, the new method enjoys accounted for about 70% of domestic Baolingbao will become the largest various advantages. For example, it can Isomaltooligosaccharide (IMO) market oligosaccharide production base with simplify the processes, shorten the with IMO sales of 46,000 tonnes in 2008 the most comprehensive variety of production time, and generate higher (TABLE 10). 21 Copyright CCM International Ltd. Email:
  • 25. CCM Newsletter Industrial Biotechnologies China News TABLE 10: Sales volume and market share of Baolingbao’s two main products Product IMO High fructose corn syrup Year 2007 2008 2007 2008 Sales volume (tonne) 27,000 33,000 57,000 62,000 Market share in China 70% 70% 11% 10% Source: CCM International According to Mr. Liu, president of oligosaccharides into food products. In Baolingbao, the company at present At present, the demand for FOS and 2008, there were about 8 FOS can meet different market demands for dietary fiber has increased year by year processors with capacity amounting to these two products, which will (FIGURE 13). With people’s increasing 40,000t/a in China (TABLE 11). As consolidate the basis of existing health awareness, these food products estimated, domestic FOS downstream customers. Besides, it will enrich its adding oligosaccharides for treatment of (milk products, beverage, biscuit, etc.) product varieties and improve the intestinal diseases have been accepted demand will reach around 80,000 ingredient system, which is expected to gradually by Chinese people. More and tonnes in 2010, with high-purity powder attract new customers and enhance more upstream and downstream FOS demand sharing around 50% of Baolingbao’s competitiveness. sectors extensively add their total. FIGURE 13: Demand for FOS in China, 2006-2010est. 80,000 80,000 70,000 Unit: tonne 60,000 44,000 50,000 40,000 25,000 30,000 16,000 20,000 8,000 10,000 0 2006 2007 2008 2009est 2010est Source: TABLE 11: Main FOS processors in China Company Launch time FOS capacity in 2008 Jiangmen Quantum Hi-tech Biological Engineering Co., Ltd. 1997 15,000t/a Yunnan Tianyuan Health-Care Food Co., Ltd. 1998 3,000t/a Guangxi Honghua Aoligao Biological Science & Technology Co., Ltd. 2003 1,500t/a Zhuhai Hightech Zone Weideli Bioengineering & Technology Co., Ltd. 1999 10,000t/a Source: CCM International 22 Copyright CCM International Ltd. Email:
  • 26. CCM Newsletter Industrial Biotechnologies China News Chinese government has promulgated a labeled ‘dietary fiber’ - liquid food (with 110,000 tonnes. Insiders believe that it policy of ‘Food Nutrition Labeling content of 1.5%), solid food (3%), which will be largely applied in food industry in Regulation’, which explicitly requires the increases water-soluble dietary fiber the near future. statement of water-soluble dietary fiber demand. In 2008, China’s output of addition volume for foods that are water-soluble dietary fiber reached BIO-MATERIALS Shenzhen Ecomann launches 5,000t/a PHA Shenzhen Ecomann Bio-technology Co., polyhydroxyalkanoics (PHAs) the construction of this production base Ltd. (Shenzhen Ecomann, production base in Zoucheng City, is divided into three phases. Upon headquartered in Shenzhen, Shandong Province on July 29th, 2009. completion, the PHAs base will achieve Guangdong Province) launched its 100,000t/a total capacity (TABLE 12). first-phase 5,000t/a With total investment of USD93 million, TABLE 12: Construction plan of Shenzhen Ecomann’s PHA base Item First phase Second phase Third phase Investment USD12 million USD51 million USD30 million Capacity 5,000t/a 50,000t/a 45,000t/a Starting time May 2008 May 2010 Early 2011 Launch time July 2009 2011 Late 2011 Source: CCM International PHAs is a kind of PHA, which is named Shenzhen Ecomann has established more. by Shenzhen Ecomann, and is mainly partnership with some Japanese and produced by using corn as raw material American end users, and has exported Besides, supply shortage of corn is currently. The company is working hard its PHA products to these countries another barrier for Chinese PHA to adopt other raw materials like potato, according to Mr. Yang. development. Five tonnes of corn is sugar cane, corn straw and vegetable needed to produce one tonne of PHA. fibre, etc. in the near future. Actually, there are some difficulties for Therefore a 100,000t/a PHA plant will PHA development. At present, China’s need 500,000 tonnes of corn every year. According to Mr. Yang, salesman of application of biodegradable materials, Though, Shenzhen Ecomann can use Shenzhen Ecomann, PHAs is produced especially PHAs, is not as extensive as other raw materials with higher price, through fermentation, a monomer that of Japan and US, due to poor such as non-grain materials like cane containing 4 carbon atoms, which has performance and high cost (as sugar with current price of USD600/t, higher tenacity for PHAs than Tianjin estimated, PHA production cost is depending on its strong fiscal ability, the Green Biotechnology Co., Ltd. (Tianjin around USD6/kg, while traditional PVC company still depends on corn, which is Green)’s PHBV (another type of PHA) plastic is around USD1/kg). However, still the major raw material. And this has with 5 carbon atoms. some high-end materials like materials become a common problem restricting for surgery in China use PHA more and the development of PHA. 23 Copyright CCM International Ltd. Email:
  • 27. CCM Newsletter Industrial Biotechnologies China News PHBV plant in Tianjin September, which will enable Tianjin At present, there are only 3 PHA Economic-Technological Development Green to become China’s largest PHA producers in China 2009 (TABLE 13). Area (TEDA) is still being constructed producer. However, Tianjin Green’s 10,000t/a and is expected to be launched this TABLE 13: PHA producers in China, 2009 Producer Establishment Time Current capacity, t/a Planned capacity, t/a Ningbo Tian’an Biologic Material Co., Ltd. 2003 2,000 5,000 Tianjin Green 2004 10 10,000 Shenzhen Ecomann 2005 5,000 100,000 Source: CCM International Established in 2005, Shenzhen production and sales of renewable City is invested by Shenzhen Ecomann, Ecomann is a technology-based materials. On May 27th 2008, the covering area of 14 hectares. enterprise specializing in development, construction of PHAs plant in Zoucheng PICTURE: Founding ceremony of Shenzhen Ecomann’s PHA project in Shandong Source: Shenzhen Ecomann Tiancheng Corn to carry out PLA project Jilin-based Tiancheng Corn renewable resources such as corn third stage project of Tiancheng Corn’s Development Co., Ltd. (Tiancheng starch and sugarcanes) project with corn deep processing and grain logistics Corn), a modern enterprise specializing capacity of 10,000t/a. It will initiate project started in 2005 (TABLE 14). The in the deep and fine processing of corn, construction before the end of 2009. company will cooperate with Jiangxi is planning to carry out a polylactic acid Provincial Academy of Sciences to (PLA, a biodegradable, thermoplastic, Using corn starch as raw material, the finish this stage of project. aliphatic polyester derived from PLA project will be constructed as the TABLE 14: Tiancheng Corn’s corn deep processing and grain logistics project Stage Investment (USD) Launch time Increased capacity (t/a) First stage 171,288,000 2006 300,000 Second stage 24,888,000 2008 300,000 Third stage 70,272,000 2010 10,000 Source: CCM International 24 Copyright CCM International Ltd. Email:
  • 28. CCM Newsletter Industrial Biotechnologies China News Tiancheng Corn is confident that its PLA Though Taizhou-based Zhejiang Hisun difficulty in getting sufficient raw material project will enjoy a promising prospect Biomaterials Co., Ltd. (Zhejiang Hisun) with low price. It was reported that in the future, thanks to the following is currently the largest PLA producer in Siping’s corn output was 500 million aspects. China with capacity of 5,000t/a, its tonnes in 2008. leading position will be replaced by Firstly, as an environmentally friendly Tiancheng Corn after the new PLA Fourthly, Tiancheng Corn enjoys very biomaterial, PLA has been widely used project launched. convenient transportation. Siping City is in the world and enjoys an increasing an important transportation hub in the demand. With increasing awareness on Secondly, PLA is a deep-processing Northeast with intensive highways and environmental protection, Chinese product with high added value. Though railways extending to all directions. government has paid more attention to being more and more widely used in Besides, it is surrounded by four airports environmentally friendly materials and various fields, there are few companies and is close to the ports of Yingkou, provided much support to their mastering its production technology at Jinzhou and Dandong. With such development. For example, Chinese present. So profit margin for PLA convenient transportation, Tiancheng government has listed the promotion production is still large. Corn will be able to save a handsome and development of biodegradable sum in product transport. materials (including PLA) in the 11th Thirdly, the project will have sufficient Five-Year Plan (2006-2010), aiming to raw material supply. Located in Siping, a It is believed that the convenient boost the development. large corn production city in Jilin transportation will contribute a lot the Province, Tiancheng Corn will have no Tiancheng Corn’s further development. NEWS IN BRIEF China holds 2009 summit forum on microbial fertilizer China held the 2009 summit forum on on microbial fertilizer prospect in China. China Agricultural University, and microbial fertilizer on Aug. 31st 2009 in Summit organizers include Chinese Chinese Ministry of Agriculture Microbial Nanyang Business Hotel, which focused Academy of Agricultural Sciences, Fertilizer Testing Center. Boeing to cooperate with China on biofuel In late Aug. 2009, according to Mr. Technology Department, Boeing is commercial production. At present, the Matthew Ganz, vice president of Boeing strengthening the cooperation with bilateral cooperation is underway. Commercial Airplanes (Boeing) as well China on biofuel development, in terms as manager from Research & of raw material sourcing and the Green Energy Group invests in biodiesel Green Energy Group Co., Ltd. (Green Jatropha-based biofuel refinery project biodiesel and other biochemical Energy Group) declared on Aug. 24th and began to cultivate Jatropha. byproducts. 2009 that the company would construct Besides, this pilot plant will also produce 25 Copyright CCM International Ltd. Email:
  • 29. CCM Newsletter Industrial Biotechnologies China News Laibin Tianren launches160,000t/a biofertilizer plant Laibin Tianren Bio-organic Fertilizer Co., City, Guangxi Province, to launch a sugar cane bagasse as raw materials. Ltd. (Laibin Tianren) on Aug. 17th 2009 160,000t/a biofertilizer plant, using crop held a foundation ceremony in Laibin wastes like corn stalks, peanut vine and China to cultivate large-scale energy forests Mr. Zhang, deputy director from the cultivate about 13,000,000 hectares more than 6,000,000 tonnes of State Forestry Administration said in energy forests nationwide. These biodiesel. early Aug. 2009 that China would energy forests will meet the demand of Ministry of Health approves 26 food additives China Ministry of Health approved 26 enzyme preparations, food spices, etc. safety. types of food additives on Aug. 6th 2009, to stipulate the additive varieties that including nutrient supplement, food can be added into food to ensure food .Beijing founds biogas technology strategic alliance On Aug. 25th 2009, Biogas Technology Bureau of Chinese Academy of development and technology support for Strategic Alliance was set up in Beijing Sciences, Tsinghua University, etc. This companies. by 19 members including High-tech alliance will focus on biogas Guangzhou establishes biotechnology service alliance Guangzhou established a biotechnology including Guangzhou Bio-Engineering Co., Ltd. of Sun Yat-sen University, etc., service alliance on Aug. 19th 2009, Center, Guangzhou Baiyunshan aiming to improve the biotechnology which was achieved by 20 members Pharmaceutical Factory, Da’an Gene development of Guangdong. Nanyang Tianrong builds 6,000t/a PPC catalyst With investment of USD6.6 million, 6,000t/a PPC (a degradable plastic) Ltd., aiming to improve its catalyst Nanyang Tianrong Technology Industry catalyst, which will exclusively supply business through this leading company Co., Ltd. (Nanyang Tianrong) is building products to Henan Tianguan Group Co., in PPC industry. Sichuan Guanghe to build 100,000t/a sweet potatoes ethanol With investment of USD98 million, Guanghe) is building 100,000t/a ethanol market depending on rich raw materials Sichuan Guanghe Energy Technology base with sweet potatoes as raw in Sichuan. Development Co., Ltd. (Sichuan material, targeting to capture ethanol 26 Copyright CCM International Ltd. Email:
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