Catalina Bermúdez González               Third semester             Molecular biologyBolivarian Pontifical University
• DNA be template for the synthesis ofTranscriptio RNA by the enzyme RNA polymerase     n              • RNA serves as an ...
   Science Daily (Jan. 9, 2012)
   The Scientifics are searching    alternatives genetic molecules    for know how the first life began   TNA is a nucle...
   A single strand of TNA can    bind with DNA and RNA    using polymerase enzymes   TNA     nucleotides  could    attac...
   TNA can fold into complex shapes that can    bind to a desired target with high affinity so    the scientifics hope to...
Beside for be a newknowledge with a greatapplication in medicine andhigh technologist especiallyin    gene      therapy,  ...
   By Sabrina Richards     (January 19, 2012)
   Use          DNA’s    simplicity to build    nanostructures   of    DNA that mimic    polymerases      or    another  ...
   DNA nanostructures is    used    to enzymatic    reactions   Meta-DNA     structures    was build using pieces    of ...
   Meta-DNA act like enzymes and providing an    opening for other single-stranded bit of    meta-DNA to bind. New meta-b...
This      development        wouldfacilitate      gene       therapyand become more efficientin             terms         ...
   These     developments       increasingly    specialized can be used extensively in    medicine, especially in gene th...
   The TNA can be adopted to    mark    places  of   micro    clots       doing       to    bring human protein Throm    ...
   With     regard    to   self-    replication of DNA if a    string        can       start    processes                ...
   MARTINEZ SANCHEZ , Lina       María. Biología    molecular. 6. ed. Medellín: UPB. Facultad de    medicina, 2012. 70 p....
The search of the origin of DNA and alternative functions
The search of the origin of DNA and alternative functions
The search of the origin of DNA and alternative functions
The search of the origin of DNA and alternative functions
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The search of the origin of DNA and alternative functions

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The search of the origin of DNA and alternative functions

  1. 1. Catalina Bermúdez González Third semester Molecular biologyBolivarian Pontifical University
  2. 2. • DNA be template for the synthesis ofTranscriptio RNA by the enzyme RNA polymerase n • RNA serves as an intermediary to carry the genetic information from the nucleus to the cytoplasmTranslation • Serves as template for the synthesis of proteins DNA RNA Double chain Single chain Desoxirribose Ribose sugar sugar Uracil Timine
  3. 3.  Science Daily (Jan. 9, 2012)
  4. 4.  The Scientifics are searching alternatives genetic molecules for know how the first life began TNA is a nucleic acid similar to DNA and RNA but has a threose (tetrose sugar) so is more simple than de ribose or desoxiribose sugar, so could assemble more easily in a probiotic world
  5. 5.  A single strand of TNA can bind with DNA and RNA using polymerase enzymes TNA nucleotides could attach by complementary base pairing to a random sequence of DNA, forming a hybrid DNA-TNA strand
  6. 6.  TNA can fold into complex shapes that can bind to a desired target with high affinity so the scientifics hope to produce a TNA as a high-specificity binding receptor for the human protein thrombin
  7. 7. Beside for be a newknowledge with a greatapplication in medicine andhigh technologist especiallyin gene therapy, ifit continues to deepen thestudy could be a new theoryabout the origin of life .
  8. 8.  By Sabrina Richards (January 19, 2012)
  9. 9.  Use DNA’s simplicity to build nanostructures of DNA that mimic polymerases or another enzymes for do biological process
  10. 10.  DNA nanostructures is used to enzymatic reactions Meta-DNA structures was build using pieces of DNA Meta-bases are three strands of double- stranded DNA. The ends of strand complement the other two
  11. 11.  Meta-DNA act like enzymes and providing an opening for other single-stranded bit of meta-DNA to bind. New meta-bases could start binding allowing for possible enzymatic reactions. The meta-DNA should eliminate unnecessary unpredictability of RNA and proteins but to become useful, have to interact proteins and the preform reactions more slowly
  12. 12. This development wouldfacilitate gene therapyand become more efficientin terms ofreduction process should bedone, but I think it is a studythat is still notvery viable becausethe target DNA requirethe interaction withproteins andreactions develop moreslowly
  13. 13.  These developments increasingly specialized can be used extensively in medicine, especially in gene therapy.
  14. 14.  The TNA can be adopted to mark places of micro clots doing to bring human protein Throm bin receptor be useful for surgery As the TNA a precursor molecule of primitive life forms could be created vectors carrying DNA strands or drugs directly to cellular receptors
  15. 15.  With regard to self- replication of DNA if a string can start processes that normally require many other factors, would be more efficient therapy. The most important thing is to give the patient the greatest possible comfort and quality of life because after all the objetive of science is always to serve the people
  16. 16.  MARTINEZ SANCHEZ , Lina María. Biología molecular. 6. ed. Medellín: UPB. Facultad de medicina, 2012. 70 p. Simpler Times: Did an Earlier Genetic Molecule Predate DNA and RNA?. Science daily [seriada en línea]. Enero 9, 2012. Disponible en: URL: http://www.sciencedaily.com/releases/2012/01/12 0109103029.htm. Consultado Enero, 2012. RICHARDS, Sabrina. Can DNA Self-replicate?.The Scientist: Magazine of the life sciences [Seriada en línea] Enero 19, 2012. Disponible en: URL:http://the-scientist.com/2012/01/19/can- dna-self-replicate/. Consultado Enero, 2012
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