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Leveraging Free Clinical Trial Data
 

Leveraging Free Clinical Trial Data

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  • Note, this presentation is a sample of the types of analysis that can be derived from clinical trials.gov. This analysis is limited to studies which mention the word pain in the title, condition or intervention or are classified as “pain” trials upon searching the clinical trials .gov website. Therefore this deck would not include clinical trials for “migraine”, for instance, if the word pain was not mentioned anywhere throughout the body of the text. Further analysis can be done to group drug interventions by brand/class/therapeutic category and/or by searching for specific conditions/diseases related to pain.

Leveraging Free Clinical Trial Data Leveraging Free Clinical Trial Data Presentation Transcript

  • Clinical Trials.gov Clinical Trials Related to Pain
  • Overview
    • This presentation illustrates the types of competitive insights that can be derived by utilizing data downloads from clinicaltrials.gov.
    • Analyses can be constrained to particular diseases, therapeutic categories 1 , study designs, phases, location, size of trials (enrollees), duration of trials, location (US or foreign), sub-grouped by industry and non-industry sponsors, etc.
    • With additional data extraction 2 and effort, it is possible to compile lists of principal investigators and compare/contrast primary endpoints.
  • There are over 72K trials listed 1 of which 7.6% are related to pain 2 !
    • There are over 72K clinical trial NCT ids listed on the clinicaltrials.gov website.
    • 5,475 of these trials are related to pain.
    • Both the volume and percent of trials related to pain is increasing annually.
    • Almost 1/10 trials listed in 2008 related to pain.
  • There are over 72K trials listed 1 of which 7.6% are related to pain 2 !
    • Over 1/3 of all pain-related trials are currently recruiting patients.
  • 51% of all pain-related trials are/have been conducted within the USA.
    • Currently 53% of open pain trials are located in the USA.
  • Over ½ of all pain-related trials list a drug as the intervention.
    • Combined, procedures and devices make up 1/4 th of the interventions for these pain trials.
  • Over 1.9M patients 1 have been enrolled for pain-related trials.
    • One out of five trials are recruiting patients limited to one age cohort (child or adult or senior).
    • Only 18% of pain-related trials recruit/ed children.
  • Industry has funded 1 40% trials and 49% of reported enrollees.
  • Pfizer has funded 1 more pain related trials than any other manufacturer.
    • The top 10 manufacturers of pain-related trials are listed above.
  • 15% of open trials are listed as Phase IV
    • The chart below is limited to open trials but includes those trials not yet recruiting.
  • Conditions of Phase IV Trials
  • Conditions of Phase IV Trials Con’t.
  • Conditions of Phase IV Trials Con’t.
  • Conditions of Phase IV Trials Con’t.
  • Conditions of Phase IV Trials Con’t.