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Carlos Santos UPR-Cayey CV

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  • 1. Carlos Santos-Pérez Urb Sierra Real Box 246 Cayey, PR 00736-9003 T 7873671030 carlos.santos9@upr.edu carlossantos791@gmail.comPROFILEInnovation and critical thinking are two factors that motivate me to learn more in thescientific research field. I am interested in all areas of science ranging from social science tonatural science. My strengths are that I am perseverant, responsible, a team member and holdmy self to a high standard. On the other hand, I recognize that I need to work on myweaknesses.E D U C AT I O NBiology Student, University of Puerto Rico- Cayey (UPR-C) — 2010-2014I am a biology major. Currently I am preparing for a Ph.D. in cancer biology. My GPA is4.00 with 109 credits approved.RESEARCH EXPERIENCEResearch Assistant, Dr. Richer Laboratory; The Endocrine Society - University of Colorado— Summer 2011My work focused on breast cancer research- MDV3100 as a Treatment for Luminal BreastCancer’. In order to perform this project I read scientific papers to understand completely theprocedures that I made in the laboratory (Real Time RT-PCR, Growth Assays,Immunocytochemistry and Western Blot) In addition to that I read additional information inorder to understand the background information and the basic science behind this researchtopic. Our aims were to determine if MDV3100 was an estrogen antagonist and how it wasable to inhibit the proliferation of the MCF7 cells (Luminal breast cancer cell line).Research Assistant, Dr. Maldonado Laboratory; UPR-Cayey — August 2011 to May 2012Using computational techniques we were looking for novel drugs to treat patients withDengue Virus. This project involved techniques related to bioinformatics, computationalbiology and In silico drug discovery and development. Also I was able to learn how to designmolecules and to test if this molecules could be possible treatment against dengue virus. Atthis point, potential possible treatments identified in our in silico approaches are going to betested in vitro.Research Assistant, Dr. Shupnik Laboratory; The Endocrine Society- University of Virginia— Summer 2012I was working on a project called ‘Dax-1 and WT-1: Novel Regulators of the LHßtranscription’. Using Western Blot, Luciferase Assay and other techniques, we looked intohow these two proteins modulate the synthesis of the Luteinizing Hormone in conjunctionwith the Gonadotropin Releasing Hormone and the proteasome degradation system of the
  • 2. cell. Luteinizing Hormone over expression is associated with diseases like Polycystic OvarianSyndrome and other female reproduction endocrine disorders. Results from this research aregoing to be publish next year.Research Assistant, Dr. Maldonado Laboratory; UPR-Cayey — August 2012 to present‘In silico drug discovery of Wee1 Kinase Inhibitors’ In this project we are identifyingpotential drug-like compounds that may inhibit uncontrolled growth of cancer cells. Rightnow, we are in the phase of finding potential protein targets associated with cancerprogression. It have been identified several targets associated with breast cancer, prostatecancer and lung cancer.HONORS• First Place, Poster Presentation, 22nd Student Research Symposium at the University of Puerto Rico at Cayey, September, 2011.• Outstanding Presentation at ABRCMS meeting (Cancer Biology Category), November 2011.• Outstanding Presentation at 23rd Student Research Symposium at the University of Puerto Rico at Cayey, December 2011.• First Place, Frank G. Brooks for Excellence in Student Research, Oral Presentation, Caribbean Regional Convention National Biological Honor Society, March, 2012.• Minority Access Program Award Recipient, The Endocrine Society April 2011.• Honor Student of the HHH association at the University of Puerto Rico at Cayey.• Outstanding Poster Presentation at ENDO 2012 (The Endocrine Society National Conference) Minority Mentoring and Poster Reception, June 2012• Outstanding Poster Presentation at SACNAS 2012, October 2012• Award for Academic Excellence; Academic Affairs Dean’s Lists at the University of Puerto Rico at Cayey, April 2011 and 2012.P O S T E R P R E S E N TAT I O N S22nd Student Research Symposium in the University of Puerto Rico at Cayey August,2011. Title presented: MDV3100 as a Treatment for Luminal Breast Cancer.
  • 3. Annual Biomedical Research Conference for Minority Students (ABRCMS) 2011 November2011 Title presented: MDV3100 as a Treatment for Luminal Breast Cancer24th Student Research Symposium in the University of Puerto Rico at Cayey August,2012 Title presented: Dax-1 and WT-1: Novel Regulators of the LHß transcription.95th The Endocrine Society National Conference (ENDO 2012), June 2012 Title presented: MDV3100 as a Treatment for Luminal Breast Cancer.Society for Advancement of Chicanos and Native Americans in Science (SACNAS) NationalConference, October 2012 Title presented: In silico Discovery of Dengue Virus Protease Inhibitors.O R A L P R E S E N TAT I O N SGEMS 2011; University of Colorado Denver, Anshutsz Medical Campus; Summer 2011. Title Presented: MDV3100 as a Treatment for Luminal Breast Cancer.23rd Student Research Symposium in the University of Puerto Rico at Cayey — December,2011 Title Presented: In Silico Drug Discovery for Dengue Protease InhibitorsCaribbean Regional Convention National Biological Honor Society at the University ofPuerto Rico at Cayey — March, 2012 Title Presented: MDV3100 as a Treatment for Luminal Breast CancerSRIP 2012 University of Virginia — August 2012 Title Presented: Dax 1 and WT 1: Novel Regulators of the LHß trasncriptionPROFESSIONAL MEMBERSHIPSAssociate Member of The Endocrine Society Attended to ENDO meetings of 2011 and 2012
  • 4. National Biological Honor Society (Tri-Beta; Zeta Epsilon Chapter) at the University ofPuerto Rico at Cayey Treasurer 2012-2013HHH Honor Society Student Member of the University of Puerto Rico at CayeySociety for Advancement of Chicanos and Native Americans in Science (SACNAS)Student Member of American Association for Cancer Research (AACR)FUTURE GOALSPhD in Cancer Biology or Cell BiologyMD/PhDREFERENCESSteven Anderson PhD Margaret Shupnik PhDVice-Chair of Research, Senior Associate Dean for Research University of VirginiaUniversity of Colorado at Denver Dean’s office: (434) 982-3408Phone: 303-724-3742 Lab office: (434)(82-0010 mas3x@virginia.edusteve.anderson@ucdenver.edu

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