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Raskar TEDMED 2013
 

Raskar TEDMED 2013

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  • Bulky, expensive , trained professionalsHere is a cataract exam with a slit lamp .. A device that hasn’t really changed for decades
  • And here getting a retinal scan .. But checkout the user interface .. It is a quarter million dollar device but the nurse has to shove my head into the eyepiece
  • And here to get eyeglasses, I am lost in a phoropter.This diagnostics while a fine solution in developed countries is not going to scale in developing countries lack of diagnostics .. Millions worldwide are suffering from conditions that have proven treatmentsReading charts appear to be an easy solution, this method has too many problems. Sharpness of legible text is very subjective. The brightness of the chart has to be very carefully chosen otherwise the pupil size will change, increasing depth of field, and allowing user to recognize even lower rows.The trial lenses + the lens frame the doctor will use also cost over $150% Reading chart tests involve using a frame or a phoropter. The doctor will swing a sequence of lenses in front of your eye and ask for which lens allows you to see the lower rows on the reading chart.
  • ImagineWe call our tool NETRA: a one dollar clip on eye piece that goes on top a cellphonenear eye tool for refractive assessmentsuch as nearsightedness/far/astigmatism
  • Many systemic diseases manifest themselves in the eye, and indeed ophthalmologist already search for indicators of such disease in the routine eye exams. Additionally, ocular manifestations require frequent monitoring, determining the follow up (the precise time intervals is critical).-----------------------------------------Just as FYI: Yellow blurry spots: Toxoplasmosis (parasitic- protozoan)White yellow deposits indicate Diabetes, Hypertension
  • Hypertension affects all blood vessels of the body and is initially asymptomatic, and can bring disastrous consequences later, like heart attack and stroke. An ophthalmological examination, even in early stage disease, detects vascular changes due to the disease.
  • For example, Many patients have a diagnosis of AIDS during an eye examination, although signs in the eye are not the first symptoms to arise.
  • The rheumatoid arthritis may have ocular symptoms that help in the diagnosis and monitoring of disease activity (autoimmune response can becontrolled by medication) .
  • The increased cholesterol is related to various cardiovascular diseases. This increase can be seen in the cornea and the eyelid.
  • Conditions which cause increased intracranial pressure can lead to the onset of papilledema (swelling of the disc), such as brain tumors.Some intracranial tumors can cause asymptomatic increased intracranial pressure, papilledema is usually observed.Metastasis usually occurs in the choroid, which is the most vascularized layer of the eye. The most common places that send tumors to the eye are lung and breast.
  • Wilson's disease can cause many systemic symptoms. The finding of Kayser-Fleischer ring in the ophthalmologic examination can help with the diagnosis. HOUSE YOUTUBE VIDEOCLIP
  • Heart attack and stroke are the leading causes of death in developed countries today. Microvascular changes are related to early alterations of these diseases. Studies involving the microcirculation could demonstrate this relationship more strongly in the future.------------FYI. Also Red spots (due to vein blockage) and Pale retina (due to artery block associated with Carotid artery disease – risk for stroke
  • The eye manifestations of parkinsons and alzheimers are not yet well studied. If you have some more info and data then we could understand how these disease work in the eye, considering the optic nerve presents a direct link to the brain/CNS.
  • Pupil opening and eyelid movement could indicate neuromuscular problems in early stage. Eye muscle can be the first muscles in your body affected by disease because of their frequent use (blinking).
  • The main component of the sclera is collagen, and this can be changed in collagen disorders.

Raskar TEDMED 2013 Raskar TEDMED 2013 Presentation Transcript

  • Eye .. Window to Health
  • 3Slit Lamp Exam Retinal Scan
  • Phoropter
  • Vitor Pamplona, Ankit Mohan, Manuel Oliveira, Ramesh Raskar SIGGRAPH 2010eyeNETRA - Refraction and CataractRx
  • Diabetic Retinopathy
  • eyeMITRA.com
  • Lawson, Roesch, Canham, Ben-Ezra, Raskar 2013Credits:Wired UK
  • Eye .. Window to CURRENT Health
  • DiabetesSyphilisGrave’s diseaseSjogrenMarfan’sSyndromeSickle CellDiseaseToxoplasmosisCoagulationDisorderTuberculosisSystemic Conditions – Lagging Indicators
  • Monitor
  • First Indicator
  • HypertensionRed SpotsBlurred VesselsColor ChangesHarrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper DIllustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R
  • AIDS, CMVBlurry vessels“Cheese and Ketchup”RetinographyHarrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper DIllustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R
  • Red SpotsThinner ScleraChoroid visible (black)Other Symptoms:Joint PainNodules in Finger JointsearlylateSlit LampRheumatoid ArthritisHarrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper DIllustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R
  • White Ring around CorneaHyper- CholesterolemiaHarrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper DIllustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R
  • Tumor, MetastasisBlurry Edges ofOptic discAccumulation of FluidHarrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper DIllustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R
  • Wilsons (Metabolism)Kayser-Fleischer Copper RingHarrison’s Principles of Internal Medicine, 2011, Longo D, Fauci A, Kasper DIllustrated Manual of Ophthalmology, MEEI, 2009, Friedman NJ, Kaiser PK, Pineda R
  • Access
  • MonitorFirst Indicator
  • MonitorFirst IndicatorPredictor
  • eyeMITRA.com
  • WidthBranchingFlow speedVascularStrokeHeart AttackMcGeechan K et al., 2009, Ann Intern Med, Meta- Analysis: Retinal Vessel Caliber and Risk for Coronary Heart DiseaseMcGeechan K et al., 2009, Am J Epidemiol, Prediction of incident stroke events based on retinal vessel caliber
  • Direct Access: Vessels, Nerve FLBody changes slowlyCo-located vascular + neurologicalInvoluntary, fine detailEye .. a Predictor?
  • Parkinson’sDiseaseAlzheimer’sDiseaseNerve Fiber LayerNeurologicalBerisha F. et al., 2007, IOVS, Retinal Abnormalities in early Alzheimer’s DiseaseGarcia-Martin E. et al., 2012, Ophthalmology, Ability and reproducibility of OCT to detect RNFL atrophy in Parkinson’s disease
  • Pupil openingEyelidStrabismuse.g. Myasthenia GravisNeuromuscularVaphiades MS et al., 2012, Curr Opin Ophthalmol, Ocular myasthenia gravis
  • InfectionsScleraCollagen Disorders
  • hurricane
  • eyeMITRA.com