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Male infertility

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  • Transcript

    • 1. MALE INFERTILITY sucks to be you
    • 2. DO I SWIM OR NOT?
    • 3. SEMEN ANALYSIS 1) Shape of sperm 2) numbers 3) Volume of semen 4) integrity of sperm 5) shape,size, movement
    • 4. remember infertility not same as impotence
    • 5. many factors contribute to a possible increase prevalence males are not always identified as infertile.
    • 6. In USA 3 million men are infertile ( Goldstein, M ) controlled causes: substances weed booze infection mumps STIs poor cryptorchid testicular late descent STIs circulation
    • 7. Smoking ...........major cause of poor sperm quality alcohol decreases T and sperm function marijuana binds to estrogen receptors in testes and causes “weird” sperm anabolic steroids decreases sperm count chemo. and radiation also high temp decreases production ( tight tidy whites, hot tubs, retained testes) single most common cause: Varicoceles, enlarged testicular veins
    • 8. Varicoceles
    • 9. varicoceles are varicose veins they increase temp and injure sperm health
    • 10. varicocoeles
    • 11. Varicocele is an abnormal enlargement of the vein that is in the scrotum draining the testicles. The testicular blood vessels originate in the abdomen and course down through the inguinal canal as part of the spermatic cord on their way to the testis. Upward flow of blood in the veins is ensured by small one-way valves that prevent backflow. Defective valves, or compression of the vein by a nearby structure, can cause dilatation of the veins near the testis, leading to the formation of a varicocele.
    • 12. these structures appear as a “ Bag of Worms” the varicocele may invove the epididymis or not
    • 13. 40% of infertile men have them 15% of all men have them increase with age large varicoceles decrease sperm numbers and T production
    • 14. the interstitial cells ( leydig cells) make T the sertoli cells make nutritional stores seminiferous tubules grow and develop sperm
    • 15. Treatment for varicoceles: IVF ( culled sperm) injected sperm micro surgery on ducts
    • 16. Azoospermia ( no sperm) 2nd greatest cause of infertility blocked infection chlamydia causes duct poorly at birth toxin working Y radiation SRY steroid unknown injury abuse
    • 17. Estrogen Mimics and Endocrine disruption
    • 18. causes: 1) environmental polution 2) certain dietary components 3) genetic abnormalities
    • 19. these influences cause undescended testes hypospadias decreased sperm count testicular cancer

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