Regulation of female monthly rhythm Dr. Sadaf Mumtaz 08-02-11
Plasma concentration of gonadotropins and ovarian hormones
Synthesis of estrogens and progesterone
Functions of estrogens <ul><li>Uterus and external female sex organs </li></ul><ul><li>Fallopian tubes </li></ul><ul><li>B...
Functions of Progesterone <ul><li>Uterus </li></ul><ul><li>Fallopian tubes </li></ul><ul><li>Breasts </li></ul>
Intermittent, pulsatile secretion of GnRH by hypothalamus stimulates pulsatile release of LH from anterior pituitary gland
Negative feedback effects of estrogens and progesterone in decreasing both LH and FSH secretion
Negative feedback effects of estrogens and progesterone in decreasing both LH and FSH secretion
Anovulatory cycles <ul><li>Preovulatory surge of LH is not of sufficient magnitude, ovulation will not occur </li></ul><ul...
Puberty and Menopause
Female Fertility <ul><li>Blockage of Sperm transport to the Ovum </li></ul><ul><ul><li>Rhythm method </li></ul></ul><ul><u...
Female Sterility <ul><li>Hyposecretion of gonadotrophic hormones </li></ul><ul><ul><li>Markers of anovulation </li></ul></...
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Regulation of female monthly rhythm

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Regulation of female monthly rhythm

  1. 1. Regulation of female monthly rhythm Dr. Sadaf Mumtaz 08-02-11
  2. 2. Plasma concentration of gonadotropins and ovarian hormones
  3. 3. Synthesis of estrogens and progesterone
  4. 4. Functions of estrogens <ul><li>Uterus and external female sex organs </li></ul><ul><li>Fallopian tubes </li></ul><ul><li>Breasts </li></ul><ul><li>Skeleton </li></ul><ul><ul><li>Osteoporosis </li></ul></ul><ul><li>Protein deposition </li></ul><ul><li>Body metabolism and fat deposition </li></ul><ul><li>Hair distribution </li></ul><ul><li>Skin </li></ul><ul><li>Electrolyte Balance </li></ul>
  5. 5. Functions of Progesterone <ul><li>Uterus </li></ul><ul><li>Fallopian tubes </li></ul><ul><li>Breasts </li></ul>
  6. 6. Intermittent, pulsatile secretion of GnRH by hypothalamus stimulates pulsatile release of LH from anterior pituitary gland
  7. 7. Negative feedback effects of estrogens and progesterone in decreasing both LH and FSH secretion
  8. 8. Negative feedback effects of estrogens and progesterone in decreasing both LH and FSH secretion
  9. 9. Anovulatory cycles <ul><li>Preovulatory surge of LH is not of sufficient magnitude, ovulation will not occur </li></ul><ul><ul><li>Failure of development of corpus luteum </li></ul></ul><ul><ul><li>The cycle is shortened by several days but the rhythm continues </li></ul></ul>
  10. 10. Puberty and Menopause
  11. 11. Female Fertility <ul><li>Blockage of Sperm transport to the Ovum </li></ul><ul><ul><li>Rhythm method </li></ul></ul><ul><ul><li>Coitus interruptus </li></ul></ul><ul><ul><li>Chemical contraceptives </li></ul></ul><ul><ul><li>Barrier methods </li></ul></ul><ul><ul><li>Sterilization </li></ul></ul><ul><li>Prevention of Ovulation </li></ul><ul><ul><li>Oral contraceptives or birth control pills </li></ul></ul><ul><ul><li>Long acting subcutaneous implantations </li></ul></ul><ul><li>Blockage of implantation </li></ul><ul><ul><li>IUCD’s </li></ul></ul><ul><ul><li>Morning after pills </li></ul></ul><ul><li>Contraception </li></ul><ul><ul><li>Refers to the process of avoiding pregnancy while engaging in sexual intercourse </li></ul></ul>
  12. 12. Female Sterility <ul><li>Hyposecretion of gonadotrophic hormones </li></ul><ul><ul><li>Markers of anovulation </li></ul></ul><ul><ul><ul><li>Progesterone </li></ul></ul></ul><ul><ul><ul><li>Temperature </li></ul></ul></ul><ul><li>Endometriosis </li></ul><ul><li>Salpingitis </li></ul><ul><li>Secretion of abnormal mucus </li></ul><ul><ul><li>Low grade infection or inflammation </li></ul></ul><ul><ul><li>Abnormal hormonal stimulation of cervix </li></ul></ul>
  13. 13. Thankyou
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