Blood glucose regulation Dr. Sadaf Mumtaz 14/02/11
<ul><li>Insulin is associated with energy abundance </li></ul><ul><li>Unbound form </li></ul>
Liver phosphorylase glucokinase Glycogen synthase Liver cells Phosphorylase & Glucose phosphatase
Glucose transporters ER Ca 2+ IP3 Glut 4 receptor Agonist Ca 2+ Glucose Tyrosine kinase
Fat metabolism Glucose Pyruvate Acetyl CoA Citrate, isocitrate ions Acetyl CoA carboxylase Acetyl CoA Malonyl-CoA Triglyce...
Ketosis
Protein metabolism
Mechanism of insulin secretion Sulphonylurea drugs
Glucagon <ul><li>Glycogenolysis </li></ul><ul><li>Gluconeogenesis </li></ul>
<ul><li>Adrenal diabetes </li></ul><ul><li>Pituitary diabetes </li></ul><ul><li>Gestational diabetes </li></ul>
Thanks Volunteers for OGTT
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Blood glucose regulation

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Blood glucose regulation

  1. 1. Blood glucose regulation Dr. Sadaf Mumtaz 14/02/11
  2. 2. <ul><li>Insulin is associated with energy abundance </li></ul><ul><li>Unbound form </li></ul>
  3. 3. Liver phosphorylase glucokinase Glycogen synthase Liver cells Phosphorylase & Glucose phosphatase
  4. 4. Glucose transporters ER Ca 2+ IP3 Glut 4 receptor Agonist Ca 2+ Glucose Tyrosine kinase
  5. 5. Fat metabolism Glucose Pyruvate Acetyl CoA Citrate, isocitrate ions Acetyl CoA carboxylase Acetyl CoA Malonyl-CoA Triglycerides Lipoprotein lipase Fatty acids Hormone sensitive lipase Α -glycerol phosphate
  6. 6. Ketosis
  7. 7. Protein metabolism
  8. 8. Mechanism of insulin secretion Sulphonylurea drugs
  9. 9. Glucagon <ul><li>Glycogenolysis </li></ul><ul><li>Gluconeogenesis </li></ul>
  10. 10. <ul><li>Adrenal diabetes </li></ul><ul><li>Pituitary diabetes </li></ul><ul><li>Gestational diabetes </li></ul>
  11. 11. Thanks Volunteers for OGTT
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