Swine flu
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  • 1. Swine flu(H1N1)
  • 2. SWINE FLU
  • 3. CONTENT’S  About Swine flu.  Causes of swine flu.  Symptom’s. Treatment. About the drug.  Prevention & precaution’s. Conclusion.
  • 4. SWINE FLU 1) What is swine flu…?  Swine flu is a disease which caused by orthomyxovirus.  Swine flu is an acute and highly spreading by contact respiratory disease.  Swine flu is also called as hog flu (or) pig flu.  Now a days the swine influenza A [H1N1] virus that has infected in human.  Normally this virus is resistant to the antiviral drugs & also resistant to vaccine.
  • 5. 1920 1940 1960 1980 2000 H1N1 H2N2 H3N2 1918: “Spanish Flu” 1957: “Asian Flu” 1968: “Hong Kong Flu” 20-40 million deaths 1-4 million deaths 1-4 million deaths
  • 6. The Influenza Virus
  • 7.  ClassifiCation :  Swine influenza is known to be caused by influenza A subtypes they are… 1) H1N1, 2) H1N2, 3) H3N1, 4) H3N2, 5) H2N3.
  • 8. Reassortment in pigs Reassortment in humans Pandemic Influenza Virus How it is caused and when…? Reassortment in birds
  • 9.  H1N1 is spread primarily through contact with an infected person like the common flu.  Routes of transmission are mainly through coughing or sneezing. Also, the virus can survive on contaminated surfaces for up to 2 hours.
  • 10. What are the Symptoms of Swine Flu …?  aCCording to the CdC, like seasonal flu, symptoms of swine flu infeCtions Can inClude:  Fever.  Cough.  Runny nose or stuffy nose.  Sore throat.  Body aches.  Headache.  Chills.  Vomiting.  Aching muscles.  Mild respiratory.
  • 11. Serious Symptoms of Swine Flu..,  Acute respiratory distress.  Bluish or gray skin color.  Eye infections.  Pneumonia.  Viral pneumonia.  Inflammation of the brain &heart.  Vomiting.
  • 12. TREATMENT  Relenza [Zanamivir], Tami flu [Oseltamivir], amantidine (symmetrel), rimantadine (Flumadine) are currently one of the most powerful drugs against the Swine flu virus. Treatment by 2 types.  Isolation  Anti-viral treatment.
  • 13. Isolation Precautions
  • 14. About the drug…,  GENERIC NAME : zanamivir  BRAND NAME : Relenza  DRUG CLASS AND MECHANISM : Zanamivir is a neuraminidase inhibitor. That prevents the spread of influenza A and B viruses. The viruses responsible for the "flu." Neuraminidase is an enzyme that is required by the influenza viruses to spread from infected cells to healthy cells
  • 15. Zanamivir blocks the action of neuraminidase there by reducing the spread of influenza. Since the spread of the viruses is prevented, The symptoms and duration of infection are reduced.. STORAGE: Store at room temperature, 15-30°C (59-86°F) PREGNANCY:Zanamivir has not been adequately evaluated in pregnant women.
  • 16. SIDE EFFECTS: The most frequent side effects are headaches, nausea, cough, vomiting and dizziness Ear, nose and throat infections may occur.  Patients who have asthma or other breathing problems do not use this drug. DOSING: Zanamivir is administered by oral inhalation.  The recommended dose is two inhalations (5 mg per inhalation) twice daily for five days.
  • 17. • No vaccine available to protect humans from swine flu • Vaccine for human seasonal influenza does not protect against H1N1 swine flu viruses due to antigenic differences, but may provide partial protection against swine H3N2 virus vACCINATION
  • 18. Preventive & Precautions measures of swine flu…?  If hot water is not available, use an alcohol-based hand gel.  Wash your hands frequently with soap & hot running water.  Get a regular seasonal flu vaccination.  Avoiding contact with ill persons.  Staying at home if you are sick, to avoid affecting
  • 19. N-95 Filtering Masks Surgical Masks Personal Protective Equipment (PPE)
  • 20. Preventive-measures
  • 21. Preventive-measures
  • 22. Conclusion Be aWare OF sWine FLu (Pig FLu).......
  • 23. Reference  For the most current information on the H1N1 influenza outbreak, visit http://www.cdc.gov/h1n1flu/  http://www.who.int/csr/disease/swineflu/en/index.html  International Committee on Taxonomy of Viruses. "The Universal Virus Database, version 4: Influenza A". http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/ l  a b c d e f "Swine influenza". The Merck Veterinary Manual. 2008. http://www.merckvetmanual.com/mvm/index.jsp?cfile=html/bc/1 . Retrieved on April 30, 2009.
  • 24.  V Trifonov, H Khiabanian, B Greenbaum, R Rabadan (30 April 2009). " The origin of the recent swine influenza A(H1N1) virus infectin ". Eurosurveillance 4 (17). http://www.eurosurveillance.org/images/dynamic/EE/V14N1 7/art19193.pdf.  Maria Zampaglione (April 29, 2009). "Press Release: A/H1N1 influenza like human illness in Mexico and the USA: OIE statement". World Organisation for Animal Health. http://www.oie.int/eng/press/en_090427.htm. Retrieved on April 29, 2009.  Swine influenza World Health Organization 27 April 2009  "Influenza A(H1N1) frequently asked questions". WHO.int. http://www.who.int/csr/disease/swineflu/faq/en/index.html. Retrieved on 2009-05-07.