Guillain-Barré syndrome is a disorder in which the bodys immune system attacks part of the peripheral nervous system Guillain-Barre syndrome damages parts of nerves. This nerve damage causes tingling, muscle weakness, and paralysis. Guillain-Barre syndrome most often affects the nerves covering (myelin sheath). Such damage is called demyelination, and it causes nerve signals to move more slowly.
Guillain-Barré is a very rare condition that occures in about one person out of 100,00. The syndrome may occur at any age, but is most common in people of both sexes between ages 30 and 50. This syndrome can occur at any age, but is rare in children under age 2.
Guillain-Barre syndrome may occur along with viral infections such as: AIDS Herpes simplex a bacterial infection
Loss of reflexes in the arms and legs Low blood pressure or poor blood pressure control Muscle weakness or loss of muscle function (paralysis) Numbness Sensation changes, including pain and tingling. Tenderness or muscle pain (may be a cramp- like pain) Uncoordinated movement (cannot walk without help)
Blurred vision and double vision Clumsiness and falling Difficulty moving face muscles Muscle contractions Palpitations (sensation of feeling the heart beat)
Breathing temporarily stops Cant take a deep breath Difficulty breathing Difficulty swallowing Drooling Fainting
Complete family history Physical examination Neurological examination Cerebrospinal fluid sample ECG Nerve conduction velocity test Pulmonary function tests Electromyography (EMG) tests the electrical activity in muscles
Electromyography (EMG) is a technique for evaluating and recording the electrical activity produced by skeletal muscles. EMG is performed using an instrument called an electromyograph, to produce a record called an electromyogram. An electromyograph detects the electrical potential generated by muscle cells when these cells are electrically or neurologically activated.
There is no cure for Guillain-Barre syndrome. However, many treatments are available to help reduce symptoms, treat complications, and speed up recovery Antibiotics Analgestics Plasmapheresis High-dose immunoglobulin therapy
Plasmapheresis Plasmapheresis is a blood purification procedure used to treat several autoimmune diseases. It is also known as therapeutic plasma exchange High-dose immunoglobulin therapy a blood product administered intravenously. It contains the pooled, IgG (immunoglobulin (antibody) extracted from the plasma of over one thousand blood donors.
Breathing difficulty (respiratory failure) Deep vein thrombosis (blood clots that form when someone is inactive or confined to bed) Increased risk of infections Low or unstable blood pressure Paralysis Pneumonia Skin damage (ulcers) Sucking food or fluids into the lungs (aspiration)